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公开(公告)号：US10646241B2
公开(公告)日：2020-05-12
申请号：US15886130
申请日：2018-02-01
发明人： Francis M. Creighton , Michael E. Sabo , Gerard Epplin , Christopher Null , James Christopher Wachtman
IPC分类号： A61B17/22 , H01F7/02 , A61M37/00 , A61K41/00 , A61B17/3207 , B82Y5/00 , A61B17/00 , A61B17/32
摘要： Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one embodiment, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Magnetic nanoparticles are provided having a non-specialized chemical coating facilitating association with a chemical composition by a user before infusion. Systems are provided for delivering a consistent infusion mass of magnetic nanoparticles to a patient.
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2.发明申请公开(公告)号：US20150230810A1
公开(公告)日：2015-08-20
申请号：US14400999
申请日：2013-05-13
发明人： Francis M. Creighton , Michael Sabo , Christopher Null , Gerard Epplin , James Christopher Wachtman
CPC分类号： A61B17/22 , A61B17/22004 , A61B17/22012 , A61B17/32002 , A61B17/3207 , A61B2017/00345 , A61B2017/00876 , A61B2017/22084 , A61B2017/320004 , A61K41/0028 , A61M37/00 , A61M2037/0007 , B82Y5/00 , H01F7/0226 , H01F7/0273 , Y10S977/811 , Y10S977/905 , Y10S977/909
摘要： Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one embodiment, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Magnetic nanoparticles are provided having a non-specialized chemical coating facilitating association with a chemical composition by a user before infusion. Systems are provided for delivering a consistent infusion mass of magnetic nanoparticles to a patient.
摘要翻译： 一些实施例提供了一种用于使用远程放置的产生磁场的定子在脉管系统中外部操纵磁性纳米颗粒的系统。 在一个实施例中，系统和方法涉及使用基于永磁体或电磁场产生定子源的流体介质中的磁性纳米颗粒的控制。 这种系统可用于增加治疗剂在诸如人类循环系统的流体培养基中的扩散，其可导致循环系统中的流体障碍（例如血管闭塞）的实质性清除，导致血流量增加。 提供了具有非专门化学涂层的磁性纳米颗粒，其在输注之前促使使用者与化学成分相关联。 提供系统用于将一致的输注质量的磁性纳米颗粒递送给患者。
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公开(公告)号：US20180221041A1
公开(公告)日：2018-08-09
申请号：US15886130
申请日：2018-02-01
发明人： Francis M. Creighton , Michael E. Sabo , Gerard Epplin , Christopher Null , James Christopher Wachtman
CPC分类号： A61B17/22012 , A61B17/22 , A61B17/22004 , A61B17/32002 , A61B17/3207 , A61B2017/00345 , A61B2017/00876 , A61B2017/22084 , A61B2017/320004 , A61K41/0028 , A61M37/00 , A61M2037/0007 , B82Y5/00 , H01F7/0226 , H01F7/0273 , Y10S977/811 , Y10S977/905 , Y10S977/909
摘要： Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one embodiment, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Magnetic nanoparticles are provided having a non-specialized chemical coating facilitating association with a chemical composition by a user before infusion. Systems are provided for delivering a consistent infusion mass of magnetic nanoparticles to a patient.
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公开(公告)号：US09883878B2
公开(公告)日：2018-02-06
申请号：US14400999
申请日：2013-05-13
发明人： Francis M. Creighton , Michael Sabo , Christopher Null , Gerard Epplin , James Christopher Wachtman
CPC分类号： A61B17/22 , A61B17/22004 , A61B17/22012 , A61B17/32002 , A61B17/3207 , A61B2017/00345 , A61B2017/00876 , A61B2017/22084 , A61B2017/320004 , A61K41/0028 , A61M37/00 , A61M2037/0007 , B82Y5/00 , H01F7/0226 , H01F7/0273 , Y10S977/811 , Y10S977/905 , Y10S977/909
摘要： Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one embodiment, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Magnetic nanoparticles are provided having a non-specialized chemical coating facilitating association with a chemical composition by a user before infusion. Systems are provided for delivering a consistent infusion mass of magnetic nanoparticles to a patient.
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