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    AFM-COUPLED MICROSCALE RADIOFREQUENCY PROBE FOR MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY
    1.
    发明申请
    AFM-COUPLED MICROSCALE RADIOFREQUENCY PROBE FOR MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY 有权
    用于磁共振成像和光谱的AFM耦合微结构无线电探头

    公开(公告)号：US20140237690A1

    公开(公告)日：2014-08-21

    申请号：US14351055

    申请日：2012-10-10

    申请人： PURDUE RESEARCH FOUNDATION

    发明人： Corey P. Neu ,  Babak Ziaie ,  Teimour Maleki-Jafarabadi ,  Charilaos Mousoulis

    IPC分类号： G01R33/48 ,  G01Q70/16 ,  G01Q30/02

    CPC分类号： G01R33/4808 ,  G01N24/08 ,  G01Q20/04 ,  G01Q30/02 ,  G01Q60/08 ,  G01Q60/52 ,  G01Q70/16 ,  G01R33/341 ,  G01R33/46

    摘要： The present disclosure is discloses the development of a new device, system, and method that combines advantages of magnetic resonance and atomic force microscopy technologies, and the utility of the new device, system, and method for a wide range of biomedical and clinical researchers. According to one aspect of the present disclosure, a device for micro-scale spectroscopy is disclosed. The micro-scale spectroscopy device includes a beam having a distal end, a proximal end, a top surface and a bottom surface, where the beam is attached to an anchor at the proximal end and further includes a tip extending substantially perpendicular from the bottom surface at or near the distal end, and a coil having at least one turn mounted to the top surface of the beam at or near the distal end opposite the tip, where the coil is capable of both transmitting and sensing electromagnetic radiation.

    摘要翻译： 本公开公开了一种结合磁共振和原子力显微技术的优点的新器件，系统和方法的开发，以及用于广泛的生物医学和临床研究人员的新器件，系统和方法的实用性。 根据本公开的一个方面，公开了一种用于微尺度光谱的装置。 微型光谱装置包括具有远端，近端，顶表面和底表面的光束，其中光束附接到近端处的锚固件，并且还包括从底表面基本垂直延伸的尖端 在远端处或附近，以及具有至少一个匝的线圈，其安装到梁的顶表面处，或者与尖端相对的远端附近，其中线圈能够传输和感测电磁辐射。

    AFM-coupled microscale radiofrequency probe for magnetic resonance imaging and spectroscopy
    2.
    发明授权
    AFM-coupled microscale radiofrequency probe for magnetic resonance imaging and spectroscopy 有权
    用于磁共振成像和光谱的AFM耦合微型射频探头

    公开(公告)号：US08884608B2

    公开(公告)日：2014-11-11

    申请号：US14351055

    申请日：2012-10-10

    申请人： Purdue Research Foundation

    发明人： Corey P. Neu ,  Babak Ziaie ,  Teimour Maleki-Jafarabadi ,  Charilaos Mousoulis

    IPC分类号： G01R33/12 ,  G01R33/20 ,  G01N24/08 ,  G01Q70/16 ,  G01Q30/02 ,  G01R33/48

    CPC分类号： G01R33/4808 ,  G01N24/08 ,  G01Q20/04 ,  G01Q30/02 ,  G01Q60/08 ,  G01Q60/52 ,  G01Q70/16 ,  G01R33/341 ,  G01R33/46

    摘要： The present disclosure is discloses the development of a new device, system, and method that combines advantages of magnetic resonance and atomic force microscopy technologies, and the utility of the new device, system, and method for a wide range of biomedical and clinical researchers. According to one aspect of the present disclosure, a device for micro-scale spectroscopy is disclosed. The micro-scale spectroscopy device includes a beam having a distal end, a proximal end, a top surface and a bottom surface, where the beam is attached to an anchor at the proximal end and further includes a tip extending substantially perpendicular from the bottom surface at or near the distal end, and a coil having at least one turn mounted to the top surface of the beam at or near the distal end opposite the tip, where the coil is capable of both transmitting and sensing electromagnetic radiation.

    摘要翻译： 本公开公开了一种结合磁共振和原子力显微技术的优点的新器件，系统和方法的开发，以及用于广泛的生物医学和临床研究者的新器件，系统和方法的实用性。 根据本公开的一个方面，公开了一种用于微尺度光谱的装置。 微型光谱装置包括具有远端，近端，顶表面和底表面的光束，其中光束附接到近端处的锚固件，并且还包括从底表面基本垂直延伸的尖端 在远端处或附近，以及具有至少一个匝的线圈，其安装到梁的顶表面处，或者与尖端相对的远端附近，其中线圈能够传输和感测电磁辐射。

    PLATFORM FOR OXYGEN GENERATION AND DELIVERY
    4.
    发明申请
    PLATFORM FOR OXYGEN GENERATION AND DELIVERY 审中-公开
    用于氧气生成和交付的平台

    公开(公告)号：US20150202399A1

    公开(公告)日：2015-07-23

    申请号：US14602203

    申请日：2015-01-21

    申请人： PURDUE RESEARCH FOUNDATION

    发明人： Babak Ziaie ,  Manuel Ochoa ,  Charilaos Mousoulis

    IPC分类号： A61M16/10 ,  A61M16/06 ,  A61M16/08 ,  A61M35/00

    CPC分类号： A61M16/101 ,  A61M13/003 ,  A61M16/0672 ,  A61M16/0875 ,  A61M35/00 ,  A61M2202/0208 ,  A61M2209/088

    摘要： A platform for oxygen generation and delivery is disclosed. The platform includes a hydrophobic substrate with at least one hydrophilic region permeable to gas flow formed thereon having an oxygen generating compound embedded in the at least one hydrophilic region. The platform further includes a microfluidic network with an inlet and an outlet bonded to the hydrophobic substrate with at least one fluid exchange region fluidly coupled to the inlet and the outlet and substantially matching the least one hydrophilic region. The microfluidic network is configured to receive an oxygen rich fluid at the inlet, communicate the oxygen rich fluid to the at least one fluid exchange region to mix with the oxygen generating compound, causing a chemical reaction resulting in formation of oxygen and a chemical byproduct, and communicate the chemical byproduct to the outlet, where the oxygen is permeated out of the at least one hydrophilic region.

    摘要翻译： 公开了一种氧气生成和输送的平台。 该平台包括具有至少一个亲水区域的疏水基底，该亲水区域可形成于其上形成有气体流的亲水区域，其具有嵌入至少一个亲水区域中的产氧化合物。 所述平台还包括具有入口和出口的微流体网络，所述入口和出口与所述疏水性基底结合，所述至少一个流体交换区域与所述入口和所述出口流体耦合，并基本匹配所述至少一个亲水区域。 微流体网络被配置为在入口处接收富氧流体，将富氧流体连通到至少一个流体交换区域以与产生氧的化合物混合，引起导致形成氧的化学反应和化学副产物， 并将化学副产物传递到出口，其中氧气渗透到至少一个亲水区域中。