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    Polyunsaturated compounds, method for preparing same and compositions containing the same
    3.
    发明授权
    Polyunsaturated compounds, method for preparing same and compositions containing the same 失效
    多不饱和化合物，其制备方法和含有它们的组合物

    公开(公告)号：US08420610B2

    公开(公告)日：2013-04-16

    申请号：US12086625

    申请日：2006-12-14

    申请人： Pascal Bordat ,  Roger Tarroux ,  Jean-Hilaire Saurat ,  Olivier Sorg ,  Jean-Louis Brayer ,  Natacha Frison

    发明人： Pascal Bordat ,  Roger Tarroux ,  Jean-Hilaire Saurat ,  Olivier Sorg ,  Jean-Louis Brayer ,  Natacha Frison

    IPC分类号： A01N43/04 ,  A01N37/00 ,  A61K31/70 ,  A61K31/19 ,  C07H15/00 ,  C07C59/00

    CPC分类号： C07D339/04 ,  A61K8/33 ,  A61K8/37 ,  A61K8/4986 ,  A61K8/585 ,  A61K8/602 ,  A61Q19/02 ,  C07B2200/09 ,  C07C403/08 ,  C07C403/10 ,  C07C403/14 ,  C07C403/20 ,  C07C2601/16 ,  C07F7/081 ,  C07F7/0812 ,  C07H15/203

    摘要： The invention concerns novel polyunsaturated compounds of formula (I) wherein: R1 represents a R′1, -A-R′1 group, R′1 being selected from —COOH, —COOR3, —CONH2, —CONHR3, —CONR3 R4, —CHO, —CH2OH, —CH2OR5, and A represents a C2-C16 alkylene, alkenylene or alkynylene; R2 represents: an optionally substituted aryl group or an optionally substituted heteroaryl group; a sugar residue or, a fatty acid residue optionally branched and/or substituted preferably at the chain terminus and particularly by hydroxy, acetoxy radical or by an optionally protected amino radical; a —OC —(CH2)n CO-tocopheryl (alpha, beta or gamma or delta) group, with 2 $m(F) n $m(F) 10; a —R′2—O—R6 group, wherein R′2 is an optionally substituted arylene group or an optionally substituted heteroarylene group, and R6 represents a hydrogen atom, a straight or branched optionally substituted C 1-C 16 alkyl, a straight or branched optionally substituted C2-C16 alkenyl, or a straight or branched C2-C16 alkynyl group, an optionally substituted tocopheryl radical or the like, an amino acid residue, or a sugar residue. The invention also concerns the compositions, in particular cosmetic and/or dermatological compositions containing at least one compound of formula (I) as well as their use as whitening and/or depigmenting agent, and the cosmetic method using said compositions.

    摘要翻译： 本发明涉及式（I）的新型多不饱和化合物，其中：R1表示R'1，-AR'1基团，R'1选自-COOH，-COOR3，-CONH2，-CONHR3，-CONR3R4，-CHO ，-CH 2 OH，-CH 2 OR 5，A表示C 2 -C 16亚烷基，亚烯基或亚炔基; R2表示：任选取代的芳基或任选取代的杂芳基; 糖残基或脂肪酸残基，优选在链末端，特别是通过羟基，乙酰氧基或任选被保护的氨基部分支化和/或取代; a -OC-（CH 2）n CO-生育酚（α，β或γ或δ）组，其中2 $ m（F）n $ m（F）10; -R'2-O-R6基团，其中R'2是任选取代的亚芳基或任选取代的亚杂芳基，R 6表示氢原子，直链或支链任选取代的C 1 -C 16烷基，直链 或支链任选取代的C 2 -C 16烯基，或直链或支链C 2 -C 16炔基，任选取代的生育酚基等，氨基酸残基或糖残基。 本发明还涉及组合物，特别是包含至少一种式（I）化合物的化妆品和/或皮肤病学组合物，以及它们作为增白剂和/或脱色素剂的用途，以及使用所述组合物的美容方法。

    Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same
    4.
    发明申请
    Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same 失效
    新型多不饱和化合物，其制备方法及其组合物

    公开(公告)号：US20100168045A1

    公开(公告)日：2010-07-01

    申请号：US12086625

    申请日：2006-12-14

    申请人： Pascal Bordat ,  Roger Tarroux ,  Jean-Hilaire Saurat ,  Olivier Sorg ,  Jean-Louis Brayer ,  Natacha Frison

    发明人： Pascal Bordat ,  Roger Tarroux ,  Jean-Hilaire Saurat ,  Olivier Sorg ,  Jean-Louis Brayer ,  Natacha Frison

    IPC分类号： A61K8/37 ,  C07H15/207 ,  A61K8/60 ,  C07C69/736 ,  C07C47/277 ,  C07C69/587 ,  C07D339/04 ,  A61K8/49 ,  C07D311/72 ,  A61K8/67 ,  C07C69/738 ,  A61K8/34 ,  A61K8/33 ,  A61Q5/00 ,  A61Q19/02

    CPC分类号： C07D339/04 ,  A61K8/33 ,  A61K8/37 ,  A61K8/4986 ,  A61K8/585 ,  A61K8/602 ,  A61Q19/02 ,  C07B2200/09 ,  C07C403/08 ,  C07C403/10 ,  C07C403/14 ,  C07C403/20 ,  C07C2601/16 ,  C07F7/081 ,  C07F7/0812 ,  C07H15/203

    摘要： The invention concerns novel polyunsaturated compounds of formula (I) wherein: R1 represents a R′1, -A-R′1 group, R′1 being selected from —COOH, —COOR3, —CONH2, —CONHR3, —CONR3, R4, —CHO, —CH2OH, —CH2OR5, and A represents a C2-C16 alkylene, alkenylene or alkynylene; R2 represents: an optionally substituted aryl group or an optionally substituted heteroaryl group; a sugar residue or, a fatty acid residue optionally branched and/or substituted preferably at the chain terminus and particularly by hydroxy, acetoxy radical or by an optionally protected amino radical; a —OC—(CH2)n CO-tocopheryl (alpha, beta or gamma or delta) group, with 2 $m(F) n $m(F) 10; a —R′2—O—R6 group, wherein R′2 is an optionally substituted arylene group or an optionally substituted heteroarylene group, and R6 represents a hydrogen atom, a straight or branched optionally substituted C1-C16 alkyl, a straight or branched optionally substituted C2-C16 alkenyl, or a straight or branched C2-C16 alkynyl group, an optionally substituted tocopheryl radical or the like, an amino acid residue, or a sugar residue. The invention also concerns the compositions, in particular cosmetic and/or dermatological compositions containing at least one compound of formula (I) as well as their use as whitening and/or depigmenting agent, and the cosmetic method using said compositions.

    摘要翻译： 本发明涉及式（I）的新型多不饱和化合物，其中：R1表示R'1，-AR'1基团，R'1选自-COOH，-COOR3，-CONH2，-CONHR3，-CONR3，R4， - CHO，-CH2OH，-CH2OR5和A表示C2-C16亚烷基，亚烯基或亚炔基; R2表示：任选取代的芳基或任选取代的杂芳基; 糖残基或脂肪酸残基，优选在链末端，特别是羟基，乙酰氧基或任选被保护的氨基上任选地支链和/或取代; a -OC-（CH 2）n CO-生育酚（α，β或γ或δ）组，其中2 $ m（F）n $ m（F）10; -R'2-O-R6基团，其中R'2是任选取代的亚芳基或任选取代的亚杂芳基，R 6表示氢原子，直链或支链任选取代的C 1 -C 16烷基，直链或支链 任选取代的C 2 -C 16烯基，或直链或支链C 2 -C 16炔基，任选取代的生育酚基等，氨基酸残基或糖残基。 本发明还涉及组合物，特别是包含至少一种式（I）化合物的化妆品和/或皮肤病学组合物，以及它们作为增白剂和/或脱色素剂的用途，以及使用所述组合物的美容方法。