公开(公告)号：US5692492A

公开(公告)日：1997-12-02

申请号：US505268

申请日：1995-09-27

Applicant: Pascal Bruna ,  Jacques Buffet

Inventor： Pascal Bruna ,  Jacques Buffet

IPC: A61M15/00 ,  A61M16/00 ,  A61M11/00

CPC classification number: A61M15/009 ,  B65D83/386 ,  A61M2016/0021 ,  A61M2205/215 ,  B65D83/201

Abstract: A hand-held inhalation-actuated spray device including a housing; tank of substance to be sprayed; a dispenser mechanism for dispensing the substance; an inhale duct; a dispenser mechanism urging device for actuating the dispenser mechanism; a locking mechanism fixed on a plate inside the housing, which includes at least one locking latch member for locking or unlocking the action of the urging device; an unlocking mechanism for displacing the latch member towards its released position while suction exists in the inhale duct; the unlocking mechanism including an electrical actuator for actuating the latch member, an electronic control circuit for the electrical actuator, a suction sensor to deliver a suction signal to the electronic control circuit on detecting suction in the inhale duct, the electronic control circuit then causing the electrical actuator to move the latch member into its released position; the device being characterized in that it further includes a position sensor for detecting that the device is in a predetermined proper orientation, in which the position sensor is connected to the electronic control circuit and the electronic control circuit is adapted to trigger actuation of the device only if the position sensor detects the predetermined proper orientation of the device.

Abstract translation: PCT No.PCT / FR94 / 00166 Sec。 371 1995年9月27日第 102（e）1995年9月27日PCT PCT 1994年2月15日PCT公布。 第WO94 / 19040号公报 日期1994年9月1日包括壳体的手持式吸入驱动喷雾装置; 要喷洒的物质罐; 用于分配物质的分配器机构; 吸气管 用于致动分配器机构的分配器机构推动装置; 固定在所述壳体内的板上的锁定机构，其包括用于锁定或解锁所述推动装置的动作的至少一个锁定闩锁构件; 解锁机构，用于在吸入管道中存在抽吸时将闩锁构件移向其释放位置; 所述解锁机构包括用于致动所述闩锁构件的电致动器，用于所述电致动器的电子控制电路;吸入传感器，用于在检测到所述吸入管道中的抽吸时向所述电子控制电路输送抽吸信号， 电动执行器将闩锁构件移动到其释放位置; 该装置的特征在于它还包括位置传感器，用于检测装置处于预定的正确定向，其中位置传感器连接到电子控制电路，并且电子控制电路适于仅触发装置的致动 如果位置传感器检测到设备的预定正确定向。

公开(公告)号：US4921487A

公开(公告)日：1990-05-01

申请号：US247271

申请日：1988-09-21

Applicant: Jacques Buffet ,  Jean-Paul Buffet ,  Jean Piani ,  Francois Paravisini

Inventor： Jacques Buffet ,  Jean-Paul Buffet ,  Jean Piani ,  Francois Paravisini

IPC: A61M5/145

CPC classification number: A61M5/1452 ,  A61M5/1454 ,  Y10S128/12

Abstract: A casing holds a syringe that contains a medicine, such as insulin, which may be driven out of the syringe by a plunger into a catheter attached to a human body. The power for the plunger drive mechanism is provided by a spiral spring mounted in the casing. A clockwork movement, regulated by a step electrical motor, controls the speed of the drive mechanism. A microprocessor controls the speed of the step electrical motor which regulates the clockwork movement. All of the components are contained in a casing which has an opening to allow the position of the plunger in the syringe to be seen from outside the casing.

Abstract translation: 壳体保持包含诸如胰岛素的药物的注射器，其可以通过柱塞从注射器驱动到附接到人体的导管中。 柱塞驱动机构的功率由安装在壳体中的螺旋弹簧提供。 由步进电机调节的发条机构控制驱动机构的速度。 微处理器控制调节发条运动的阶梯电动机的速度。 所有的部件都包含在壳体中，该壳体具有开口，以允许柱塞在注射器中的位置从壳体的外部看到。

公开(公告)号：US4747832A

公开(公告)日：1988-05-31

申请号：US864173

申请日：1986-05-16

Applicant: Jacques Buffet

Inventor： Jacques Buffet

IPC: A61M5/142 ,  A61M5/20

CPC classification number: A61M5/14276 ,  A61M2205/3515 ,  Y10S128/12

Abstract: Disclosed is an implantable device for the injection of fluid into a patient's body. The device includes a non-invasive external part which magnetically cooperates with the implanted portion through a magnetic field. The device is entirely mechanical and is capable of delivering both a continuous dose of fluid as well as instantaneous dose of fluid. The mechanism comprises a fluid reservoir, a catheter, an elastic means, a regulating means, a magnetic drive means, a gear transmission means and a flow adjustment means.

Abstract translation: 公开了一种用于将流体注入患者体内的可植入装置。 该装置包括通过磁场与注入部分磁性配合的非侵入式外部部件。 该装置是完全机械的，并且能够输送连续剂量的流体以及瞬时剂量的流体。 该机构包括流体储存器，导管，弹性装置，调节装置，磁驱动装置，齿轮传动装置和流量调节装置。

公开(公告)号：US4574814A

公开(公告)日：1986-03-11

申请号：US396397

申请日：1982-07-08

Applicant: Jacques Buffet

Inventor： Jacques Buffet

IPC: A61N1/05 ,  A61N1/368

CPC classification number: A61N1/368 ,  A61N1/056

Abstract: A probe is provided for a pacemaker which is associated by one of its end portions with the pacemaker and by its opposite end portion with the auricle and the ventricle of the heart. It comprises two conductors which form a one-piece assembly and which are associated with each other by means allowing them to slide axially with respect to each other, namely two tubes or sleeves fitting one into the other and movable with respect to each other. An annular space is provided between said tubes.

Abstract translation: 提供了一种用于起搏器的探针，该起搏器由其起始器之一的一个端部与其起始器的相对端部与耳廓和心脏的心室相关联。 它包括形成一体式组件的两个导体，它们通过允许它们相对于彼此轴向滑动的方式彼此相关联，即两个管或套管彼此相配合并可相对移动。 在所述管之间设置环形空间。

公开(公告)号：US4846180A

公开(公告)日：1989-07-11

申请号：US107480

申请日：1987-10-13

Applicant: Jacques Buffet

Inventor： Jacques Buffet

IPC: A61N1/372

CPC classification number: A61N1/37252 ,  A61N1/37258

Abstract: A method and apparatus for adjusting an implantable heart stimulator (1) in dependence on the effort exerted by the patient wearing the stimulator, using an external control programmer (2) associated in operation with the stimulator (1), a number of typical operating programs p.sub.i of the stimulator (1) being previously defined, each corresponding to a type of effort by the patient and characterized by specific values v of at least one operating parameter p of the stimulator (1), and the stimulator (1) is externally actuated, via the control programmer (2), so as to select the desired operating program p.sub.i, the result of the selection being that the stimulator (1) then operates in accordance with the selected operating program, so that the patient can automatically choose an operating program p.sub.i for the stimulator (1) in dependence on an effort to be made. The typical operating programs p.sub.i and consequently the specific values V of the parameters p, i.e., the maximum stimulation frequency F and the time D necessary for reaching the frequency F, are stored in the memory of a microprocessor (3) found in the stimulator (1).

Abstract translation: 一种用于根据由佩戴刺激器的患者施加的努力，使用与刺激器（1）相关联的外部控制编程器（2）来调整可植入心脏刺激器（1）的方法和装置，许多典型的操作程序 刺激器（1）的pi预先定义，每个对应于患者的努力类型，并且由刺激器（1）的至少一个操作参数p的特定值v表征，并且刺激器（1）被外部致动 通过控制编程器（2），以便选择所需的操作程序pi，所述选择的结果是所述刺激器（1）根据所选择的操作程序进行操作，使得患者能够自动选择操作 刺激者（1）的程序pi依赖于努力。 典型的操作程序pi以及因此参数p的特定值V即达到频率F所需的最大刺激频率F和时间D被存储在在刺激器中找到的微处理器（3）的存储器中 1）。

公开(公告)号：US4313441A

公开(公告)日：1982-02-02

申请号：US30816

申请日：1979-04-17

Applicant: Jacques Buffet

Inventor： Jacques Buffet

IPC: A61N1/372 ,  A61N1/36

CPC classification number: A61N1/37252 ,  A61N1/37247

Abstract: A process of regulating by an extra-corporeal control unit an implanted cardiac stimulator comprising a pulse generator and a pair of electrodes, comprises controlling the stimulator so that it functions at a fixed rhythm independent of normal cardiac rhythm and detecting by the extra-corporeal unit successive pulses emitted by the stimulator. After each of selected stimulator pulses detected, and during the whole period between successive stimulator pulses, a train of successive control pulses is transmitted by the control unit and is received by the stimulator as binary information "1". On the contrary, no train of successive control pulses is transmitted during the whole period between other successive stimulator pulses and this is received as binary information "0". The binary information thus received is used to regulate the operation of the stimulator. The extra-corporeal unit displays the pulses emitted by the stimulator to verify that the regulator is effective.

Abstract translation: 由体外控制单元调节包括脉冲发生器和一对电极的植入式心脏刺激器的过程包括控制刺激器，使得其以独立于正常心律的固定节律起作用并且由体外单位检测 由刺激器发射的连续脉冲。 在检测到所选择的刺激器脉冲中的每一个之后，并且在连续的刺激器脉冲之间的整个周期期间，连续的控制脉冲串被控制单元发送，并被刺激器作为二进制信息“1”接收。 相反，在其他连续的刺激器脉冲之间的整个时间段内不传送连续的控制脉冲序列，并且作为二进制信息“0”被接收。 这样接收的二进制信息用于调节刺激器的操作。 超外部单元显示刺激器发出的脉冲，以验证调节器是否有效。

公开(公告)号：US4522208A

公开(公告)日：1985-06-11

申请号：US583578

申请日：1984-02-24

Applicant: Jacques Buffet

Inventor： Jacques Buffet

IPC: A61N1/37 ,  A61N1/372 ,  A61N1/36

CPC classification number: A61N1/3706 ,  A61N1/37252

Abstract: In order to determine parameter values of an implanted programmable pacemaker, each parameter value is assigned a time .DELTA.T which is a fraction of the pacing period T in the magnetic mode. In a pair of successive pacing intervals with the combined duration of 2T, one interval is shortened and the other lengthened by the amount .DELTA.T. With the pacemaker in the magnetic mode, the parameter value is identified by observing the position of the middle pulse in the double interval 2T.

Abstract translation: 为了确定植入的可编程起搏器的参数值，每个参数值被分配一个时间DELTA T，该时间是磁模式中起搏周期T的一小部分。 在组合持续时间为2T的一对连续的起搏间隔中，一个间隔被缩短，另一个间隔延长了DELTA T。起搏器在磁模式下，通过观察中间脉冲的位置来识别参数值 双重间隔2T。

公开(公告)号：US4471783A

公开(公告)日：1984-09-18

申请号：US361804

申请日：1982-03-25

Applicant: Jacques Buffet

Inventor： Jacques Buffet

IPC: A61N1/36 ,  A61N1/378 ,  H01M2/10 ,  H01M6/14 ,  A61N1/00

CPC classification number: H01M6/14 ,  A61N1/378 ,  H01M2/10

Abstract: This cardiac stimulator comprises a sealed metal case (2), means for generating electric direct current which are electrically connected to at least one electronic circuit (13) adapted to deliver heart-stimulating pulses, the current generating means, comprising an anode (3), a cathode (4) and an electrolyte, being disposed directly in the case (2). The electronic circuit (13) is enclosed in a sealed cell (12) provided with an output terminal (14) for electrically connecting an electrode (14') and another terminal (15) for electrically connecting one of the anode and cathode poles (3, 4). This stimulator has a low weight and reduced over-all dimensions.

Abstract translation: 该心脏刺激器包括密封的金属外壳（2），用于产生电连接到适于递送心脏刺激脉冲的至少一个电子电路（13）的电气直流电的装置，所述电流产生装置包括阳极（3） ，阴极（4）和电解质，直接设置在壳体（2）中。 电子电路（13）被封装在具有用于电连接电极（14'）和另一端子（15）的输出端子（14）的密封电池（12）中，用于将阳极和阴极（3）中的一个电连接 ，4）。 该刺激器具有较低的重量和减少的所有尺寸。

公开(公告)号：US4418695A

公开(公告)日：1983-12-06

申请号：US235553

申请日：1981-02-18

Applicant: Jacques Buffet

Inventor： Jacques Buffet

IPC: A61N1/365 ,  A61N1/37 ,  A61N1/36

CPC classification number: A61N1/37 ,  A61N1/365

Abstract: An implantable cardiac stimulator having terminals for connections with a cardiac probe comprises an amplifier for receiving and amplifying a signal received from the probe, a band pass filter for filtering the output of the amplifier and a level detector which responds to a predetermined level of the amplified and filtered signal. A logic module comprising a clock, a microprocessor and a memory is connected with the level detector and with a magnetically operable control switch which can be actuated by a permanent magnet outside the body. The stimulator automatically performs the normal therapeutic function of palliating the patients cardiac insufficiencies and also provides means for monitoring operation of the stimulator and the condition and degree of dependency of the patient on the stimulator.

Abstract translation: 具有用于与心脏探针连接的终端的可植入心脏刺激器包括用于接收和放大从探针接收的信号的放大器，用于对放大器的输出进行滤波的带通滤波器以及响应预定电平的放大器的电平检测器 和滤波信号。 包括时钟，微处理器和存储器的逻辑模块与电平检测器连接，并具有可由身体外部的永磁体驱动的可磁化操作的控制开关。 刺激器自动执行缓解患者心脏功能不全的正常治疗功能，并且还提供用于监测刺激器的操作以及患者对刺激器的依赖性的状况和程度的手段。