Well Defined stars with segmented arms
    3.
    发明申请
    Well Defined stars with segmented arms 审中-公开
    定义明星与分段武器

    公开(公告)号:US20110263722A1

    公开(公告)日:2011-10-27

    申请号:US12799412

    申请日:2010-04-23

    IPC分类号: C08F20/06 A61K47/32

    摘要: The present invention relates to the preparation and use of well defined star macromolecules wherein the composition of the arms are selected to induce self assembly when the multi-arm segmented star macromolecules are dispersed in a liquid. The self assembled star macromolecules modify the rheology of the dispersing media. When targeting use in aqueous based systems the inner shell of the star macromolecules comprise non-ionizable monomer units. Compositions comprising the self assemblable star macromolecules are suitable for use as rheology modifiers in a number of applications including cosmetic and personal care compositions.

    摘要翻译: 本发明涉及明确定义的星形大分子的制备和用途,其中当多臂分段的星形大分子分散在液体中时,选择臂的组成以诱导自组装。 自组装的星形大分子改变了分散介质的流变性。 当在含水系统中靶向时,星形大分子的内壳包含不可离子化的单体单元。 包含自组装星形大分子的组合物适用于许多应用中的流变改性剂,包括化妆品和个人护理组合物。

    Multi-Functional Nano-Device
    8.
    发明申请
    Multi-Functional Nano-Device 审中-公开
    多功能纳米器件

    公开(公告)号:US20110286935A1

    公开(公告)日:2011-11-24

    申请号:US13109256

    申请日:2011-05-17

    摘要: A universal drug delivery platform for monoclonal antibody-based therapeutics is described. This universal platform resolves the problems of immunogenic response associated with the present monoclonal antibody based therapeutics by providing a multifunctional nano-device which comprises a well defined core/shell nano-structure that can function as a drug delivery platform linked to a monoclonal antibody through a single linking group.

    摘要翻译: 描述了用于基于单克隆抗体的治疗剂的通用药物递送平台。 该通用平台通过提供多功能纳米装置来解决与本发明的基于单克隆抗体的治疗相关的免疫原性应答的问题,该多功能纳米装置包含明确定义的核/壳纳米结构,其可以作为通过以下方式与单克隆抗体连接的药物递送平台 单链接组。

    ATOM TRANFER DISPERSION POLYMERIZATION
    10.
    发明申请
    ATOM TRANFER DISPERSION POLYMERIZATION 有权
    原子转移分散聚合

    公开(公告)号:US20100273906A1

    公开(公告)日:2010-10-28

    申请号:US12451581

    申请日:2008-05-23

    IPC分类号: C08J9/00 C08F36/20

    摘要: The present disclosure describes a two-step batch dispersion polymerization process for the preparation of substantially uniformed-sized functional (co)polymer particles. The first step of the process includes polymerizing at least one first radically (co)polymerizable monomer by a free radical polymerization process to form a (co)polymer in a stable colloidal dispersion and the second step includes polymerizing the at first radically (co)polymerizable monomer or an additional radically (co)polymerizable monomer in the stable colloidal dispersion by a living/controlled radical (co)polymerization process.

    摘要翻译: 本公开描述了用于制备基本上均匀尺寸的功能(共)聚合物颗粒的两步间歇分散聚合方法。 该方法的第一步包括通过自由基聚合方法聚合至少一种第一自由基(共)可聚合单体,以在稳定的胶态分散体中形成(共)聚合物,第二步包括首先从根本上聚合(共)可聚合 单体或通过活/受控自由基(共)聚合方法在稳定的胶体分散体中的另外的自由基(共)可聚合单体。