公开(公告)号：US08959798B2

公开(公告)日：2015-02-24

申请号：US13530689

申请日：2012-06-22

申请人： Patrick Pfister

发明人： Patrick Pfister

IPC分类号： A43B13/18 ,  A43B13/12 ,  A43B7/22 ,  A43B13/14 ,  A43B21/26 ,  B29D35/14

CPC分类号： A43B13/12 ,  A43B7/223 ,  A43B13/125 ,  A43B13/127 ,  A43B13/146 ,  A43B21/26 ,  B29D35/142

摘要： A midsole element to be mounted to the lower surface of an insole of a shoe as a heel, wherein the midsole element has a upper surface adapted to be mounted on the lower surface of the insole and a lower surface, wherein the midsole element comprises a core and a resilient compression element being softer than the core. The midsole element allows a pivoting movement of the upper surface of the midsole element against the lower surface of the midsole element in, at least, an essentially transverse direction to the longitudinal axis of the midsole element in a mounted state, wherein the core has a form of a rounded cone or sphere within the resilient compression element. The midsole element can also be mounted to the lower surface of a shoe under the forefoot portion, wherein the core has the form of a round ridge.

摘要翻译： 一种中底元件，其被安装到鞋的鞋垫的下表面作为鞋跟，其中中底元件具有适于安装在鞋内底的下表面上的上表面和下表面，其中中底元件包括 芯部和弹性压缩元件比芯部软。 中底部元件允许在安装状态下，中底部元件的上表面在中底部元件的下表面中至少基本上横向于中底元件的纵向轴线的方向上的枢转运动，其中，芯具有 弹性压缩元件内的圆锥体或球体的形式。 中底部元件也可以安装在鞋前面脚下部的下表面上，其中，该芯具有圆形脊的形式。

公开(公告)号：US20090307925A1

公开(公告)日：2009-12-17

申请号：US12482800

申请日：2009-06-11

申请人： Patrick Pfister

发明人： Patrick Pfister

IPC分类号： A43B13/18 ,  A43B13/12 ,  A43B13/38 ,  A43B23/00

CPC分类号： A43B13/12 ,  A43B7/223 ,  A43B13/125 ,  A43B13/145 ,  A43B13/146 ,  A43B21/26

摘要： A shoe comprises a sole and an insole. The sole comprises an upper surface being in contact with the lower surface of the insole. Said upper surface of the sole comprises at least two depressions being complementary with embossments provided on the lower surface of the insole, allowing a pivoting movement of the front and/or back portion of the insole against the lower outsole surface of the shoe in, at least, an essentially transverse direction to the longitudinal axis of the shoe, when the foot wearing the shoe is pivoted against ground. To support this movement the insole is more rigid than the outsole and is attached to the outsole.

摘要翻译： 鞋包括鞋底和鞋垫。 鞋底包括与鞋内底的下表面接触的上表面。 鞋底的所述上表面包括与设置在鞋垫的下表面上的压花互补的至少两个凹部，允许内底的前部和/或后部部分相对于鞋的下外底表面枢转运动， 至少，当穿着鞋的脚摆靠在地面上时，基本上横向于鞋的纵向轴线。 为了支持这种运动，鞋垫比外底更刚硬，并且附着在外底上。

公开(公告)号：US09914760B2

公开(公告)日：2018-03-13

申请号：US14318641

申请日：2014-06-28

申请人： Patrick Pfister ,  Matthew E. Rogers ,  Khalid Jerod Parris

发明人： Patrick Pfister ,  Matthew E. Rogers ,  Khalid Jerod Parris

IPC分类号： C12Q1/68 ,  C07K14/705 ,  G01N33/50

CPC分类号： C07K14/705 ,  C12Q1/6809 ,  C12Q2600/136 ,  G01N33/5058 ,  G01N2333/705 ,  G01N2500/04 ,  G01N2570/00

摘要： Provided here are new methods to identify specific families of mammalian odorant receptors for odorants or aroma, particularly indole and skatole malodors and their use in assays that may be used to discover compounds that modulate (blocking, enhancing, masking or mimicking compounds) their activity. Orphan mouse odorant receptors are identified from olfactory sensory neurons that respond to target compounds. The resulting receptors as well as their human counterparts can be screened in assays against test compounds to confirm their identity as odorant or aroma receptors, particularly malodor receptors and subsequently discover for example modulators that inhibit the perception of the malodor in humans.

公开(公告)号：US20120297641A1

公开(公告)日：2012-11-29

申请号：US13530689

申请日：2012-06-22

申请人： Patrick Pfister

发明人： Patrick Pfister

IPC分类号： A43B13/38

CPC分类号： A43B13/12 ,  A43B7/223 ,  A43B13/125 ,  A43B13/127 ,  A43B13/146 ,  A43B21/26 ,  B29D35/142

摘要： A midsole element to be mounted to the lower surface of an insole of a shoe as a heel, wherein the midsole element has a upper surface adapted to be mounted on the lower surface of the insole and a lower surface, wherein the midsole element comprises a core and a resilient compression element being softer than the core. The midsole element allows a pivoting movement of the upper surface of the midsole element against the lower surface of the midsole element in, at least, an essentially transverse direction to the longitudinal axis of the midsole element in a mounted state, wherein the core has a form of a rounded cone or sphere within the resilient compression element. The midsole element can also be mounted to the lower surface of a shoe under the forefoot portion, wherein the core has the form of a round ridge.

摘要翻译： 一种中底元件，其被安装到鞋的鞋垫的下表面作为鞋跟，其中中底元件具有适于安装在鞋内底的下表面上的上表面和下表面，其中中底元件包括 芯部和弹性压缩元件比芯部软。 中底部元件允许在安装状态下，中底部元件的上表面在中底部元件的下表面中至少基本上横向于中底元件的纵向轴线的方向上的枢转运动，其中，芯具有 弹性压缩元件内的圆锥体或球体的形式。 中底部元件也可以安装在鞋前面脚下部的下表面上，其中，该芯具有圆形脊的形式。

公开(公告)号：US08266825B2

公开(公告)日：2012-09-18

申请号：US12482800

申请日：2009-06-11

申请人： Patrick Pfister

发明人： Patrick Pfister

IPC分类号： A43B13/18

CPC分类号： A43B13/12 ,  A43B7/223 ,  A43B13/125 ,  A43B13/145 ,  A43B13/146 ,  A43B21/26

摘要： A shoe having an outsole and an insole. The outsole has an upper surface in contact with the lower surface of the insole. The upper surface of the outsole has at least two depressions being complementary with embossments provided on the lower surface of the insole, allowing a pivoting movement of the front and/or back portion of the insole against the lower outsole surface of the shoe in, at least, an essentially transverse direction to the longitudinal axis of the shoe, when the foot wearing the shoe is pivoted against the ground. To support this movement the insole is more rigid than the outsole and is attached to the outsole.

摘要翻译： 具有外底和鞋垫的鞋。 外底具有与鞋内底的下表面接触的上表面。 外底的上表面具有至少两个凹陷，其与设置在鞋垫的下表面上的压花互补，允许内底的前部和/或后部部分相对于鞋的下外底表面枢转运动， 至少，当穿着鞋的脚摆靠在地面上时，基本上横向于鞋的纵向轴线。 为了支持这种运动，鞋垫比外底更刚硬，并且附着在外底上。