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    Guanidino compounds
    4.
    发明授权
    Guanidino compounds 失效
    胍基化合物

    公开(公告)号：US07456183B2

    公开(公告)日：2008-11-25

    申请号：US10474331

    申请日：2002-04-08

    申请人： Daniel Chu ,  Rustum Boyce ,  David Duhl ,  Bryan Chang

    发明人： Daniel Chu ,  Rustum Boyce ,  David Duhl ,  Bryan Chang

    IPC分类号： A61K31/47 ,  A61K31/425 ,  A61K31/415 ,  A61K31/40 ,  A61P7/00 ,  C07D209/02 ,  C07D209/44 ,  C07D209/46 ,  C07D209/48 ,  C07D217/22 ,  C07D235/24 ,  C07D235/28 ,  C07D277/62 ,  C07D403/02

    CPC分类号： C07D209/46 ,  C07D209/48 ,  C07D217/24 ,  C07D235/08 ,  C07D235/10

    摘要： Compounds having the general structure I are provided. X and Y are independently selected from the group consisting of CH2, N, NR9, C═O, C═S, S═O, SO2, S, O, (CR6R7)n, C(═O)—(CR6R7)n, and C(═S)—(CR6R7)n, where n is 1, 2, or 3. W is selected from the group consisting of (formula I) and L is selected from the group consisting of N, O, S═O, SO2, C(O), NC(O), NC(S), OC(O), OC(S), C(NR10), C(NOR10), and a covalent bond. Z1, Z2, and Z3 are independently selected from the group consisting of substituted carbon and nitrogen. Compounds of formula I are agonists of the melanocortin-4 receptor (“MC-4r2) and therefore may have useful properties for controlling diseases related to MC-4r action in humans, such as obesity and type II diabetes.

    摘要翻译： 提供具有一般结构I的化合物。 X和Y独立地选自CH 2，N，NR 9，CO，CS，SO，SO 2，S ，（O） - （CR 6），（O） - （CR 6） C（-S） - （CR 6 R 7）N ，和C（-S） - （CR 6） 其中n为1,2或3.W选自（式I），L选自N，O，SO，SO 2， C（O），NC（O），NC（S），OC（O），OC（S），C（NR 10） ，和共价键。 Z 1，Z 2，Z 3和Z 3独立地选自取代的碳和氮。 式I化合物是黑皮质素-4受体（“MC-4r2”）的激动剂，因此可能具有控制人类MC-4r作用相关疾病如肥胖和II型糖尿病的有用性质。

    SOG dispensing system and its controlling sequences
    8.
    发明授权
    SOG dispensing system and its controlling sequences 有权
    SOG分配系统及其控制顺序

    公开(公告)号：US06245148B1

    公开(公告)日：2001-06-12

    申请号：US09300432

    申请日：1999-04-28

    申请人： Mike Liang ,  Peter Baw ,  John Chiu ,  Bryan Chang

    发明人： Mike Liang ,  Peter Baw ,  John Chiu ,  Bryan Chang

    IPC分类号： B05C1110

    CPC分类号： H01L21/6715 ,  B05C11/08

    摘要： The present invention relates to a SOG (Spin-On-Glass) dispensing system and its controlling sequences and, more particularly, to a SOG dispensing system allowing for continuous production and its controlling sequences According to the present invention, a buffer tank, whose wall is set a plurality of level sensors at different level heights, is connected between a source tank with a SOG bottle inside and a coating unit of prior art and then SOG is supplied for a time interval from the source tank into the buffer tank by control signals from these level sensors. Besides, the buffer tank is surrounded with a cooling unit to provide a low temperature enviroment allowing for prolonging life time of SOG and preventing organic solvent inside SOG from evaporating and then crystallizing to form contamination particles at wall of the SOG dispensing system. Thus, the resultant SOG dispensing system, according to the present invention, can resolve a shortcoming of discontinuous production of prior art due to a need for changing the SOG bottle, as well as another shortcoming of residue of the SOG bottle, thereby considerably raising operating efficient of the dispensing system by reducing its idle time and lowering fabrication cost by saving a SOG waste.

    摘要翻译： 本发明涉及一种SOG（旋转玻璃）分配系统及其控制顺序，更具体地涉及允许连续生产的SOG分配系统及其控制顺序。根据本发明，一种缓冲罐，其壁 设置多个不同高度的液位传感器，连接在内部具有SOG瓶的源罐和现有技术的涂层单元之间，然后通过控制信号从源箱向缓冲罐供给SOG一段时间间隔 从这些液位传感器。 此外，缓冲罐被冷却单元包围，以提供低温环境，允许延长SOG的寿命并防止SOG内的有机溶剂蒸发，然后结晶以在SOG分配系统的壁处形成污染颗粒。 因此，根据本发明的所得SOG分配系统可以解决由于需要改变SOG瓶而导致的现有技术的不连续生产的缺点，以及SOG瓶的残留物的另一缺点，从而大大提高了操作 通过减少其空闲时间并降低制造成本，通过节省SOG废物来实现分配系统的高效性。