公开(公告)号：US20050148598A1

公开(公告)日：2005-07-07

申请号：US10497731

申请日：2002-12-06

申请人： Paul O'Neill ,  Adrian Higson ,  Sara Taylor ,  Edward Irving

发明人： Paul O'Neill ,  Adrian Higson ,  Sara Taylor ,  Edward Irving

IPC分类号： C07D493/18 ,  C07D519/00 ,  A61K31/496 ,  A61K31/355 ,  C07D493/14

CPC分类号： C07D493/18 ,  C07D519/00

摘要： The present invention relates to compounds of general formula (13), and pharmaceutically acceptable salts thereof, in which: n=an integer of from 1 to 4; A represents a trioxane-containing residue; B represents a group having the general formula: -D-E-F-, in which D is linked to A and represents an atom or group selected from the following (a, b, c, d), E represents a bivalent, optionally substituted organic radical; and F is linked to C and represents a group selected from the following: (e, f, g, h) and C represents a group containing at least two nitrogen atoms, (13).

摘要翻译： 本发明涉及通式（13）的化合物及其药学上可接受的盐，其中：n = 1至4的整数; A表示含三氧杂环己烷的残基; B表示具有以下通式的基团：-D-E-F-，其中D与A连接并且表示选自以下（a，b，c，d）中的原子或基团，E表示二价任选取代的有机基团; 并且F与C连接并且表示选自以下的基团：（e，f，g，h），C表示含有至少两个氮原子的基团，（13）。

公开(公告)号：US20050070595A1

公开(公告)日：2005-03-31

申请号：US10497735

申请日：2002-12-06

申请人： Paul O'Neil ,  Adrian Higson ,  Sara Taylor ,  Edward Irving

发明人： Paul O'Neil ,  Adrian Higson ,  Sara Taylor ,  Edward Irving

IPC分类号： C07D493/18 ,  A61K31/335 ,  A61K33/26 ,  A61K45/00 ,  A61P33/06 ,  A61P35/00 ,  A61P43/00 ,  C07D493/20 ,  C07D493/04

CPC分类号： C07D493/20

摘要： This application relates to compounds of the general formula (11), and pharmaceutically acceptable salts thereof, in which R is selected from the group comprising optionally substituted alkyl, aryl, bisalkyl or bisaryl ester, bisalkyl or bisaryl ether, acetal, ketal, boronate, silyl ether, carbamate, carbonate, sulphate, sulphonate, phosphate and phosphonate, and to processes for their production. The compounds are useful as medicaments, in particular for the treatment of malaria and cancer.

摘要翻译： 本申请涉及通式（11）的化合物及其药学上可接受的盐，其中R选自任选取代的烷基，芳基，双烷基或双芳基醚，双烷基或双芳基醚，缩醛，缩酮，硼酸酯， 甲硅烷基醚，氨基甲酸酯，碳酸盐，硫酸盐，磺酸盐，磷酸盐和膦酸盐，并进行其生产。 这些化合物可用作药物，特别是用于治疗疟疾和癌症。

公开(公告)号：US20110054983A1

公开(公告)日：2011-03-03

申请号：US12644892

申请日：2009-12-22

申请人： Andreas J. Hunn ,  Nicolas Tabbal ,  Sara Taylor ,  John Brady

发明人： Andreas J. Hunn ,  Nicolas Tabbal ,  Sara Taylor ,  John Brady

IPC分类号： G06Q10/00 ,  G06Q30/00 ,  G06Q50/00

CPC分类号： G06Q30/02 ,  G06F16/313 ,  G06Q10/063 ,  G06Q10/10 ,  G06Q30/0244 ,  G06Q30/0254

摘要： A method of selecting a website for delivery of targeted content to an audience member computer based on attitude values associated with audience members who participate in a computer implemented survey is disclosed. The survey response information, as well as website visitation information, and demographic information associated with the audience members may be collected and stored in a central database. An attitude value may be determined from the survey response information and/or the other information for the audience members. The attitude value may indicate the audience member's view about an issue, topic, product, service or the like. The attitude value in conjunction with other website visitation information may be used to select a website for delivery of the targeted content to the audience members.

摘要翻译： 公开了一种基于与参与计算机实施的调查的观众成员相关联的态度值来选择用于向观众成员计算机传送目标内容的网站的方法。 调查回复信息以及网站访问信息和与受众成员相关联的人口统计信息可以被收集并存储在中央数据库中。 姿态值可以根据调查响应信息和/或观众成员的其他信息来确定。 态度值可以指示观众成员关于问题，主题，产品，服务等的观点。 与其他网站访问信息一起使用的态度价值可以用于选择一个网站来向观众提供有针对性的内容。

公开(公告)号：US10475047B2

公开(公告)日：2019-11-12

申请号：US12644892

申请日：2009-12-22

申请人： Andreas J. Hunn ,  Nicolas Tabbal ,  Sara Taylor ,  John Brady

发明人： Andreas J. Hunn ,  Nicolas Tabbal ,  Sara Taylor ,  John Brady

IPC分类号： G06Q30/02 ,  G06F16/31 ,  G06Q10/06 ,  G06Q10/10

摘要： A method of selecting a website for delivery of targeted content to an audience member computer based on attitude values associated with audience members who participate in a computer implemented survey is disclosed. The survey response information, as well as website visitation information, and demographic information associated with the audience members may be collected and stored in a central database. An attitude value may be determined from the survey response information and/or the other information for the audience members. The attitude value may indicate the audience member's view about an issue, topic, product, service or the like. The attitude value in conjunction with other website visitation information may be used to select a website for delivery of the targeted content to the audience members.

公开(公告)号：US20120192214A1

公开(公告)日：2012-07-26

申请号：US13365020

申请日：2012-02-02

申请人： Andreas Hunn ,  Nicolas Tabbal ,  Sara Taylor ,  John Brady

发明人： Andreas Hunn ,  Nicolas Tabbal ,  Sara Taylor ,  John Brady

IPC分类号： H04N21/258

CPC分类号： G06Q30/02 ,  G06Q30/0271 ,  H04N21/23424 ,  H04N21/252 ,  H04N21/258 ,  H04N21/25883 ,  H04N21/25891 ,  H04N21/4755 ,  H04N21/6582 ,  H04N21/812

摘要： A method of selecting a television channel or program for delivery of targeted content to an audience member television display based on attitude values associated with audience members who participate in a computer implemented survey is disclosed. The survey response information, as well as television viewing information, and demographic information associated with the audience members may be collected and stored in a central database. An attitude value may be determined from the survey response information and/or the other information for the audience members. The attitude value may indicate the audience member's view about an issue, topic, product, service or the like. The attitude value in conjunction with other television viewing information may be used to select a television channel or program for delivery of the targeted content to the audience members.

摘要翻译： 公开了一种基于与参与计算机实施的调查的观众成员相关联的态度值来选择用于将目标内容传送到观众成员电视显示器的电视频道或节目的方法。 调查响应信息以及电视观看信息以及与观众相关联的人口信息可以被收集并存储在中央数据库中。 姿态值可以根据调查响应信息和/或观众成员的其他信息来确定。 态度值可以指示观众成员关于问题，主题，产品，服务等的观点。 结合其他电视观看信息的姿态值可以用于选择用于将目标内容传送给观众的电视频道或节目。

公开(公告)号：US20110119278A1

公开(公告)日：2011-05-19

申请号：US12942469

申请日：2010-11-09

申请人： Andreas J. Hunn ,  Nicolas Tabbal ,  Sara Taylor ,  John Brady

发明人： Andreas J. Hunn ,  Nicolas Tabbal ,  Sara Taylor ,  John Brady

IPC分类号： G06F17/30

CPC分类号： G06Q30/02 ,  G06Q30/0251

摘要： A method of selecting a website for delivery of targeted content to an audience member computer based on attitude values associated with audience members who participate in a computer implemented survey is disclosed. The survey response information, as well as website visitation information, and demographic information associated with the audience members may be collected and stored in a central database. An attitude value may be determined from the survey response information and/or the other information for the audience members. The attitude value may indicate the audience member's view about an issue, topic, product, service or the like. The attitude value in conjunction with other website visitation information may be used to select a website for delivery of the targeted content to the audience members.

摘要翻译： 公开了一种基于与参与计算机实施的调查的观众成员相关联的态度值来选择用于向观众成员计算机传送目标内容的网站的方法。 调查回复信息以及网站访问信息和与受众成员相关联的人口统计信息可以被收集并存储在中央数据库中。 姿态值可以根据调查响应信息和/或观众成员的其他信息来确定。 态度值可以指示观众成员关于问题，主题，产品，服务等的观点。 与其他网站访问信息一起使用的态度价值可以用于选择一个网站来向观众提供有针对性的内容。