公开(公告)号：US5043250A

公开(公告)日：1991-08-27

申请号：US554239

申请日：1990-07-17

申请人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Jr., Raymond W. Ryan

发明人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Jr., Raymond W. Ryan

IPC分类号： G03F7/038

CPC分类号： G03F7/038

摘要： Radiation-sensitive compositions which are especially useful in the production of negative-working lithographic printing plates comprise a photocrosslinkable polymer containing the photosensitive group ##STR1## as an integral part of the polymer backbone and, in an amount sufficient to improve the properties of the composition, a poly(N-acyl-alkleneimine). The poly(N-acyl-alkyleneimine) improves the properties of the radiation-sensitive composition in regard to such factors as shelf life, image contrast, developability and reduction in mottle and thereby provides a superior lithographic printing plate.

摘要翻译： 特别可用于制备负性平版印刷版的辐射敏感组合物包含含有作为聚合物主链的组成部分的光敏基团“IMAGE”的光可交联聚合物，其用量足以改善组合物的性质 ，聚（N-酰基 - 亚烯亚胺）。 关于诸如保质期，图像对比度，显影性和斑点减少等因素，聚（N-酰基 - 亚烷基亚胺）改善了辐射敏感性组合物的性质，从而提供了优越的平版印刷版。

公开(公告)号：US5061601A

公开(公告)日：1991-10-29

申请号：US554232

申请日：1990-07-17

申请人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Raymond W. Ryan, Jr.

发明人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Raymond W. Ryan, Jr.

IPC分类号： C08L67/06 ,  G03F7/038

CPC分类号： G03F7/0384 ,  C08L67/06

摘要： Radiation-sensitive compositions which are especially useful in the production of negative-working lithographic printing plates comprise a photocrosslinkable polymer containing the photosensitive group ##STR1## as an integral part of the polymer backbone and, in an amount sufficient to improve the properties of the composition, a polymer of vinyl pyrrolidone. The polymer of vinyl pyrrolidone improves the properties of the radiation-sensitive composition in regard to such factors as shelf life, image contrast, and developability and thereby provides a superior lithographic printing plate.

摘要翻译： 特别可用于制备负性平版印刷版的辐射敏感组合物包含含有作为聚合物主链的组成部分的光敏基团“IMAGE”的光可交联聚合物，其用量足以改善组合物的性质 ，乙烯基吡咯烷酮的聚合物。 关于诸如保质期，图像对比度和显影性的因素，乙烯基吡咯烷酮的聚合物改善了辐射敏感组合物的性能，从而提供了优异的平版印刷版。

公开(公告)号：US5045432A

公开(公告)日：1991-09-03

申请号：US554229

申请日：1990-07-17

申请人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Raymond W. Ryan, Jr.

发明人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Raymond W. Ryan, Jr.

IPC分类号： G03F7/038

CPC分类号： G03F7/038

摘要： Radiation-sensitive compositions which are especially useful in the production of negative-working lithographic printing plates comprise a photocrosslinkable polymer containing the photosensitive group ##STR1## as an integral part of the polymer backbone and, in an amount sufficient to improve the properties of the composition, both a poly(N-acyl-alkyleneimine) and an unsaturated polyester such as a polyester derived from fumaric acid and a 4,4'-isopropylidenediphenol. The combination of a poly(N-acylalkyleneimine) and an unsaturated polyester improves the properties of the radiation-sensitive composition in regard to such factors as shelf life, image contrast, developability, ink receptivity and reduction in mottle and thereby provides a superior lithographic printing plate.

摘要翻译： 特别可用于制备负性平版印刷版的辐射敏感组合物包含含有作为聚合物主链的组成部分的光敏基团“IMAGE”的光可交联聚合物，其用量足以改善组合物的性质 ，聚（N-酰基 - 亚烷基亚胺）和不饱和聚酯如衍生自富马酸的聚酯和4,4'-异丙基二苯酚。 关于聚（N-酰基亚烷基亚胺）和不饱和聚酯的组合改善了辐射敏感组合物在保质期，图像对比度，显影性，油墨接受性和斑点的还原等因素方面的性能，从而提供优异的平版印刷 盘子。

公开(公告)号：US5061600A

公开(公告)日：1991-10-29

申请号：US554230

申请日：1990-07-17

申请人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Raymond W. Ryan, Jr.

发明人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Raymond W. Ryan, Jr.

IPC分类号： G03F7/038

CPC分类号： G03F7/0384

摘要： Radiation-sensitive compositions which are especially useful in the production of negative-working lithographic printing plates comprise a photocrosslinkable polymer containing the photosensitive group ##STR1## as an integral part of the polymer backbone and, in an amount sufficient to improve the properties of the composition, both a polymer of vinyl pyrrolidone and an unsaturated polyester such as a polyester derived from fumaric acid and a 4,4'-isopropylidine-diphenol. The combination of a polymer of vinyl pyrrolidone and an unsaturated polyester improves the properties of the radiation-sensitive composition in regard to such factors as shelf life, image contrast, developability and ink receptivity and thereby provides a superior lithographic printing plate.

摘要翻译： 特别可用于制备负性平版印刷版的辐射敏感组合物包含含有作为聚合物主链的组成部分的光敏基团“IMAGE”的光可交联聚合物，其用量足以改善组合物的性质 ，乙烯基吡咯烷酮和不饱和聚酯的聚合物，例如衍生自富马酸的聚酯和4,4'-异丙基 - 二酚。 关于乙烯基吡咯烷酮和不饱和聚酯的聚合物的组合改善了辐射敏感组合物在保质期，图像对比度，显影性和油墨接收性等因素方面的性能，从而提供了优越的平版印刷版。

公开(公告)号：US5053315A

公开(公告)日：1991-10-01

申请号：US554231

申请日：1990-07-17

申请人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Raymond W. Ryan, Jr.

发明人： Paul R. West ,  James E. Mitchell ,  Gary R. Miller ,  Paul R. Josephson, Jr. ,  Raymond W. Ryan, Jr.

IPC分类号： G03F7/038

CPC分类号： G03F7/038

摘要： Radiation-sensitive compositions which are especially useful in the production of negative-working lithographic printing plates comprise a photocrosslinkable polymer containing the photosensitive group ##STR1## as an integral part of the polymer backbone and, in an amount sufficient to improve the properties of the composition, an unsaturated polyester such as a polyester derived from fumaric acid and a 4,4'-isopropylidenediphenol. The unsaturated polyester additive improves the properties of the radiation-sensitive composition in regard to processing characteristics and ink receptivity and thereby provides a superior lithographic printing plate.

摘要翻译： 特别可用于制备负性平版印刷版的辐射敏感组合物包含含有作为聚合物主链的组成部分的光敏基团“IMAGE”的光可交联聚合物，其用量足以改善组合物的性质 ，不饱和聚酯如来自富马酸的聚酯和4,4'-异丙基二苯酚。 不饱和聚酯添加剂改善了辐射敏感组合物在加工特性和油墨接受性方面的性能，从而提供了优越的平版印刷版。

公开(公告)号：US5141842A

公开(公告)日：1992-08-25

申请号：US676131

申请日：1991-03-27

申请人： James E. Mitchell ,  Paul R. West ,  Paul R. Josephson, Jr.

发明人： James E. Mitchell ,  Paul R. West ,  Paul R. Josephson, Jr.

IPC分类号： C07D213/89 ,  C07D215/60 ,  C07D219/02 ,  G03F7/038

CPC分类号： C07D213/89 ,  C07D215/60 ,  C07D219/02 ,  G03F7/0384

摘要： Radiation-sensitive compositions which are especially useful in the production of negative-working lithographic printing plates comprise a photocrosslinkable polymer, containing the photosensitive group ##STR1## as an integral part of the polymer backbone, and a print-out composition which produces an optical density difference upon exposure to activating radiation and thereby enables the exposed image on the printing plate to be seen before the plate is processed. The print-out composition comprises a leuco form of a dye having one or more removable hydrogen atoms, the removal of which forms a compound colored differently from the leuco form; a photooxidant which has a photoscissionable nitrogen-oxygen bond, the photooxidant serving to convert the leuco dye to the differently colored form when the composition is exposed to activating radiation; and a heteroaromatic amine N-oxide which functions to improve the photo-efficiency of the print-out composition and thereby increase the print-out density.

摘要翻译： 特别可用于制备负性平版印刷版的辐射敏感性组合物包括含有作为聚合物主链的组成部分的光敏基团“IMA”的光可交联聚合物，以及产生光密度的印刷组合物 在曝光到激活辐射之后的差异，从而使得在板被处理之前可以看到在印版上的曝光图像。 印刷组合物包含具有一个或多个可移除氢原子的染料的无色形式，其去除形成与无色形式不同的化合物; 具有可分离的氮 - 氧键的光氧化剂，当组合物暴露于活化辐射时，该光氧化剂用于将无色染料转化为不同颜色的形式; 以及用于提高印刷组合物的光效率并因此增加印刷出密度的功能的杂芳族胺N-氧化物。

公开(公告)号：US5141839A

公开(公告)日：1992-08-25

申请号：US676130

申请日：1991-03-27

申请人： James E. Mitchell ,  Paul R. West ,  Paul R. Josephson, Jr.

发明人： James E. Mitchell ,  Paul R. West ,  Paul R. Josephson, Jr.

IPC分类号： G03F7/004 ,  G03F7/027 ,  G03F7/031 ,  G03F7/105

CPC分类号： G03F7/105

摘要： Negative-working lithographic printing plates comprise a radiation-sensitive composition having incorporated therein a photocrosslinkable polymer, containing the photosensitive group ##STR1## as an integral part of the polymer backbone, and a print-out composition which produces an optical density difference upon exposure to activating radiation and thereby enables the exposed image on the printing plate to be seen before the plate is processed. The print-out composition comprises a leuco form of a dye having one or more removable hydrogen atoms, the removal of which forms a compound colored differently from the leuco form; a photooxidant which has a photoscissionable nitrogen-oxygen bond, the photooxidant serving to convert the leuco dye to the differently colored form when the composition is exposed to activating radiation; and a heteroaromatic amine N-oxide which functions to improve the photo-efficiency of the print-out composition and thereby increase the print-out density.

摘要翻译： 负性平版印刷版包括其中掺入光可交联聚合物的辐射敏感组合物，其含有作为聚合物主链的整体部分的光敏基团“IMAGE”;以及一种在暴露于 激活辐射，从而使得在板被处理之前能够看到印版上的曝光图像。 印刷组合物包含具有一个或多个可移除氢原子的染料的无色形式，其去除形成与无色形式不同的化合物; 具有可分离的氮 - 氧键的光氧化剂，当组合物暴露于活化辐射时，该光氧化剂用于将无色染料转化为不同颜色的形式; 以及用于提高印刷组合物的光效率并因此增加印刷出密度的功能的杂芳族胺N-氧化物。

公开(公告)号：US20120070563A1

公开(公告)日：2012-03-22

申请号：US12884596

申请日：2010-09-17

申请人： James E. Mitchell ,  William Heaton ,  Dishuan Chu ,  Terry Morgan ,  Justin Peterson ,  Joseph Traina

发明人： James E. Mitchell ,  William Heaton ,  Dishuan Chu ,  Terry Morgan ,  Justin Peterson ,  Joseph Traina

IPC分类号： B05D3/02 ,  B05D3/10

CPC分类号： A61L31/16 ,  A61F2240/001 ,  A61F2250/0068 ,  A61L2300/416

摘要： Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.

摘要翻译： 公开的方法和装置用于将治疗物质或药物装载在具有沿其长度的多个侧开口的中空丝的内腔空间内，所述多个侧开口形成具有多个侧药物输送开口的中空药物洗脱支架。 在中空支架的内腔空间内装载药物包括药物填充步骤，其中药物与溶剂或分散介质混合。 可以在反向填充过程和/或正向填充过程中用药物溶液或悬浮液填充管腔空间。 在药物填充步骤之后，进行溶剂或分散介质提取步骤，以从内腔空间中提取溶剂或分散介质，使得只有药物保留在中空支架内。 可以对中空支架的外表面执行支架清洁步骤。

公开(公告)号：US20120070562A1

公开(公告)日：2012-03-22

申请号：US12884578

申请日：2010-09-17

申请人： Salvador Avelar ,  James E. Mitchell

发明人： Salvador Avelar ,  James E. Mitchell

IPC分类号： B05D3/00

CPC分类号： A61L31/16 ,  A61F2/86 ,  A61F2240/001 ,  A61F2250/0068 ,  A61L31/14 ,  A61L2300/416 ,  A61L2300/802

摘要： Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.

摘要翻译： 公开的方法和装置用于将治疗物质或药物装载在具有沿其长度的多个侧开口的中空丝的内腔空间内，所述多个侧开口形成具有多个侧药物输送开口的中空药物洗脱支架。 在中空支架的内腔空间内装载药物包括药物填充步骤，其中药物与溶剂或分散介质混合。 可以在反向填充过程和/或正向填充过程中用药物溶液或悬浮液填充管腔空间。 在药物填充步骤之后，进行溶剂或分散介质提取步骤，以从内腔空间中提取溶剂或分散介质，使得只有药物保留在中空支架内。 可以对中空支架的外表面执行支架清洁步骤。

公开(公告)号：US08027756B2

公开(公告)日：2011-09-27

申请号：US11608064

申请日：2006-12-07

申请人： Robert B. Davis ,  Daniel J. Boorman ,  L. Kirk Gagnon ,  William L. Goodman ,  Alan R. Jacobsen ,  William A. Miller ,  James E. Mitchell ,  Victor A. Riley ,  William F. Royce ,  William D. Tafs

发明人： Robert B. Davis ,  Daniel J. Boorman ,  L. Kirk Gagnon ,  William L. Goodman ,  Alan R. Jacobsen ,  William A. Miller ,  James E. Mitchell ,  Victor A. Riley ,  William F. Royce ,  William D. Tafs

IPC分类号： G05D1/06

CPC分类号： G01C23/00 ,  G01C21/00 ,  G01C23/005 ,  G08G5/0021 ,  G08G5/025

摘要： Systems, computer program products, and methods for displaying navigation performance based flight path deviation information during the final approach segment to a runway and during landing of non-precision flight modes are provided. Improved graphical depictions of navigation performance based flight path deviation information provide pilots and flight crew members with clear, concise displays of the dynamic relationship between ANP and RNP, mode and aspect of flight and related procedures, intersecting flight paths, and current actual flight path deviation from a predefined flight path during the final approach segment to a runway and during landing. For example, an enhanced IAN display may include NPS-type deviation scales to show RNP/ANP relationships and predetermined RNP markers to alert the pilots and flight crew members that the FMC has transitioned from an NPS display for RNAV (LNAV/VNAV) flight procedures to an enhanced IAN display for a non-precision (non-xLS) approach and/or landing.

摘要翻译： 提供了系统，计算机程序产品以及在最终进场段到跑道和非精确飞行模式着陆期间显示导航性能的飞行路径偏差信息的方法。 基于导航性能的飞行路径偏差信息的改进图形描述为飞行员和飞行机组成员提供了ANP和RNP之间的动态关系，飞行模式和方面以及相关程序，相交飞行路径以及当前实际飞行路径偏差的清晰简明的显示 在最终进场段期间从预定义的飞行路径到跑道和着陆期间。 例如，增强的IAN显示器可以包括NPS型偏差标度以显示RNP / ANP关系和预定的RNP标记，以警告飞行员和飞行机组成员FMC已经从用于RNAV（LNAV / VNAV）飞行程序的NPS显示器转换 到非精确（非xLS）方法和/或着陆的增强型IAN显示。