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公开(公告)号：US4532930A
公开(公告)日：1985-08-06
申请号：US483806
申请日：1983-04-11
申请人： Peter A. Crosby , Christopher N. Daly , David K. Money , James F. Patrick , Peter M. Seligman , Janusz A. Kuzma
发明人： Peter A. Crosby , Christopher N. Daly , David K. Money , James F. Patrick , Peter M. Seligman , Janusz A. Kuzma
CPC分类号： A61N1/36185 , A61N1/36032
摘要： A cochlear implant system includes an electrode array (1) comprising multiple platinum ring electrodes in a silastic carrier to be implanted in the cochlea of the ear. A receiver-stimulator (3) containing a semiconductor integrated circuit and other components is implanted in the patient adjacent the ear to receive data information and power through tuned coil (5) using an inductive link (6) from a patient-wearable external speech processor (7) including an integrated circuit and various components which is configured or mapped to emit data signals from an EPROM programmed to suit each patient electrical stimulation perceptions through testing of the patient and his implanted stimulator/electrode using a diagnostic and programming unit (12) connected to the processor by an interface unit (10). The system allows use of various speech processing strategies including dominant spectral peak and amplitude and compression of voice pitch so as to include voiced sounds, unvoiced glottal sounds and prosodic information. Biphastic pulses are supplied to various combinations of electrodes by a switch controlled current sink in various modes of operation. In-place testing of the implant is also provided. Various safety features are incorporated to insure that harmful impulses are not imposed on the patient.Transmission of data is by a series of discrete data bursts which represent the chosen electrode(s), the electrode mode configuration, the stimulating current, and amplitude determined by the duration of the amplitude burst.
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公开(公告)号：US4522209A
公开(公告)日：1985-06-11
申请号：US483862
申请日：1983-04-11
CPC分类号： A61F2/0095 , A61N1/37 , A61N2001/37294
摘要： A test system for a sealed, sterile package containing a cochlear prosthesis electrode. A light-emitting diode has its two leads in contact with at least two different conducting bands on the electrode. The prosthesis, which is externally-powered, is operated so as to supply a stimulus current between the two bands. If the light-emitting diode is illuminated, proper operation of the prosthesis can be verified without unsealing the package.
摘要翻译： 一种用于密封的无菌包装的测试系统，其包含耳蜗假体电极。 发光二极管的两个引线与电极上的至少两个不同的导电带接触。 外部供电的假体被操作以便在两个带之间提供刺激电流。 如果发光二极管被照亮，则可以在不打开封装的情况下验证假体的适当操作。
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公开(公告)号：US4533988A
公开(公告)日：1985-08-06
申请号：US252313
申请日：1981-04-09
CPC分类号： H02M7/217 , H02M2007/2195 , Y02B70/1408 , Y10S128/903
摘要： There is disclosed a bridge circuit which finds particularly advantageous use in medical prostheses which can be programmed externally and which can transmit telemetry signals. The entire circuit is implemented on a single CMOS integrated circuit. Depending upon the values of two control bits, the bridge circuit functions to derive a powering potential from an externally transmitted signal, with or without regulation. Externally transmitted programming signals are detectable, and telemetry signals can be transmitted from the chip as well. There is no active switching of bridge devices during power rectification mode, and instead they are biased on continuously. This allows the rectifier to operate at carrier frequencies as high as several megahertz. All of this is achieved by using conventional CMOS processing techniques, without requiring any extra diffusion steps.
摘要翻译： 公开了一种桥接电路，其在医疗假体中具有特别有利的用途，其可以在外部编程并且可以传输遥测信号。 整个电路在单个CMOS集成电路上实现。 根据两个控制位的值，桥接电路用于从外部传输的信号导出有或没有调节的供电电位。 外部传输的编程信号是可检测的，并且遥测信号也可以从芯片传输。 在电源整流模式下，桥式器件没有主动切换，而是连续偏置。 这允许整流器在高达几兆赫兹的载波频率下工作。 所有这些都通过使用常规CMOS处理技术来实现，而不需要任何额外的扩散步骤。
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公开(公告)号：US4453162A
公开(公告)日：1984-06-05
申请号：US376276
申请日：1982-05-10
CPC分类号： A61N1/37211 , A61N1/37 , H04B1/44 , Y10S128/903
摘要： A transmitter for a medical prosthesis which is highly efficient, and also permits rapid starting and stopping so that the same coil can be used for both transmission and reception without undue delays between the two modes of operation. During transmission, a tuned circuit, consisting of the coil and a capacitor, is pumped at a frequency equal to the resonant frequency. Transmission is concluded when almost all of the energy in the tuned circuit is in the form of a voltage across the capacitor and when the current through the inductor is approximately zero. This allows the inductor to be used immediately for reception. At the start of the next transmission cycle, the voltage which is maintained across the capacitor is used to initially energize the tuned circuit.
摘要翻译： 用于医疗假体的发射器是高效的，并且还允许快速启动和停止，使得相同的线圈可以用于发送和接收，而不会在两种操作模式之间出现不适当的延迟。 在传输期间，由线圈和电容器组成的调谐电路以等于谐振频率的频率被泵浦。 当调谐电路中的几乎所有的能量都是电容器两端的电压，并且当通过电感器的电流大约为零时，传输结束。 这允许电感器立即用于接收。 在下一个传输周期开始时，使用保持在电容器两端的电压来初始激励调谐电路。
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公开(公告)号：US4337776A
公开(公告)日：1982-07-06
申请号：US182820
申请日：1980-08-29
CPC分类号： A61N1/3706 , A61N2001/083
摘要： A pacer which facilitates the measurements of both electrode impedance and stimulation threshold. When activated by an external magnet, a sequence of reducing-amplitude stimulating pulses is generated, with successive pulses in the sequence being separated by full-amplitude pulses. This pulse alternation scheme allows long test sequences, and therefore measurements with greater resolution, because full-amplitude pacing pulses are always present (even though at a slightly reduced rate). The reduction in amplitude of successive pulses is determined by the electrode impedance rather than being predetermined, and thus the examination of a skin potential recording allows electrode impedance to be determined along with the capture threshold.
摘要翻译： 一种便于测量电极阻抗和刺激阈值的起搏器。 当由外部磁体激活时，产生减小幅度刺激脉冲序列，序列中的连续脉冲被全幅脉冲分开。 这种脉冲交替方案允许长的测试序列，因此具有更高分辨率的测量，因为全幅度起搏脉冲总是存在（即使以稍微降低的速率）。 连续脉冲的振幅的减小由电极阻抗而不是预先确定，因此对皮肤电位记录的检查允许电极阻抗与捕获阈值一起确定。
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公开(公告)号：US4408608A
公开(公告)日：1983-10-11
申请号：US252319
申请日：1981-04-09
IPC分类号： H04R25/04 , A61F2/00 , A61F2/18 , A61F11/00 , A61F11/04 , A61N1/36 , A61N1/372 , H02J17/00 , H04R25/00 , A61N1/30
CPC分类号： A61N1/372 , A61N1/36032
摘要： There is disclosed an implantable tissue-stimulating prosthesis, such as a cochlear prosthesis, which can not only be implemented in single-chip form, but which also permits great flexibility in stimulation strategy and data transmission format. Only sixteen electrodes are required for stimulating fifteen different sites. Each site is stimulated by a biphasic pulse under control of two adjacent electrodes whose polarities are reversed in the middle of the site stimulation cycle. Although the transmission scheme requires a pulse-width modulation format, the precise form of the format can be varied in order to accommodate widely different stimulation strategies. For example, only a single site may be stimulated during each transmission frame or multiple sites may be stimulated during the same frame. Although only one site can be stimulated at any instant of time, the system cycling is so fast that "simultaneous" site stimulations are perceived. The system is designed for minimum power usage, and its operation is fail-safe in that no site may be stimulated for longer than a pre-set time interval.
摘要翻译： 公开了一种植入式组织刺激假体，例如耳蜗假体，其不仅可以以单芯片形式实现，而且还可以在刺激策略和数据传输格式中具有很大的灵活性。 只需十六个电极刺激十五个不同的地点。 在两个相邻电极的控制下，每个位点受到两相脉冲的刺激，其极性在位点刺激周期的中间反转。 虽然传输方案需要脉冲宽度调制格式，但格式的精确形式可以变化，以适应广泛不同的刺激策略。 例如，在每个传输帧期间可以仅刺激单个站点，或者可以在同一帧期间刺激多个站点。 虽然在任何时间只能刺激一个站点，但是系统循环是如此之快，以至于可以感知到“同步”站点刺激。 该系统设计用于最小功率使用，并且其操作是故障安全的，因为不会刺激长时间超过预设时间间隔。
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公开(公告)号：US4466440A
公开(公告)日：1984-08-21
申请号：US320338
申请日：1981-11-12
CPC分类号： A61N1/365 , H04B14/062
摘要： There is disclosed a heart pacer in which the sensed signal is processed in the time domain rather than the frequency domain. A delta modulator operates directly on the sensed electrogram signal, without any intervening filtering, to derive a sequence of bits whose states represent increments or decrements in the sensed signal amplitude. Decisions as to cardiac activity are based on the sequence of bit values thus generated. The particular delta modulator disclosed is highly advantageous in that it allows highly accurate tracking and representation of the sensed signal.
摘要翻译： 公开了一种心脏起搏器，其中感测信号在时域而不是频域中被处理。 增量调制器直接对所感测的电描记图信号进行操作，而无需任何中间滤波，以导出其状态表示感测信号幅度中的增量或减量的位序列。 关于心脏活动的决定基于如此产生的位值的序列。 公开的特定增量调制器是非常有利的，因为它允许高精度地跟踪和表示所感测的信号。
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公开(公告)号：US4408604A
公开(公告)日：1983-10-11
申请号：US251708
申请日：1981-04-06
申请人： Michael S. Hirshorn , Michael Skalsky , Petrus A. van Berkum , Loraine K. Holley , David K. Money
发明人： Michael S. Hirshorn , Michael Skalsky , Petrus A. van Berkum , Loraine K. Holley , David K. Money
CPC分类号： A61N1/0565
摘要： A porous cardiac pacemaker electrode comprising a concavo-convex electrode cap having a plurality of apertures therethrough and an electrode shaft having a supporting edge formed thereon to which the concave surface of the electrode cap is joined. The porous cardiac pacemaker electrode is produced by deforming a platinum plate into a concavo-convex shaped cap member, forming a plurality of selectively spaced apertures through the electrode cap member to make the electrode cap substantially porous, forming an electrode shaft having a supporting edge, and joining the supporting edge of the electrode shaft to the concave surface of the electrode cap member.
摘要翻译： 一种多孔心脏起搏器电极，包括具有穿过其中的多个孔的凹凸电极帽和形成有所述电极帽的凹面的所述支撑边缘的电极轴。 多孔心脏起搏器电极通过将铂板变形成凹凸形的帽构件而制成，通过电极帽构件形成多个选择性间隔的孔，以使电极帽基本上是多孔的，形成具有支撑边缘的电极轴， 并且将电极轴的支撑边缘连接到电极帽构件的凹面。
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公开(公告)号：US4414979A
公开(公告)日：1983-11-15
申请号：US237089
申请日：1981-02-23
摘要： There is disclosed an implantable bone growth stimulator whose direct-current output can be monitored. Rather than to interrogate the device, e.g., by using a control magnet as in the heart pacer art, the device continuously transmits pulses of electromagnetic energy at a rate proportional to the current being delivered. The continuous transmission expends no more than about five percent of the total power. Instead of using an electrode lead as an antenna for radiating the pulses, a separate coil inside the device is utilized so that the therapeutic current itself is in no way affected by the pulse transmission. Effective transmission is achieved despite the fact that the device is hermetically sealed in a titanium case. Also included is an electronic switch for drastically limiting power drawn from the battery until implantation takes place, in order to provide an extended shelf life.
摘要翻译： 公开了可以监测其直流输出的可植入骨生长刺激器。 而不是如在心脏起搏器技术中使用控制磁体来询问装置，装置以与正被传递的电流成比例的速率连续传输电磁能量的脉冲。 连续传输不超过总功率的百分之五。 代替使用电极引线作为用于辐射脉冲的天线，利用器件内部的单独的线圈，使得治疗电流本身不受脉冲传输的影响。 尽管器件被气密地密封在钛壳中，但实现有效的传输。 还包括一种电子开关，用于大大限制从电池抽取的电力，直到植入发生，以提供延长的保质期。
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公开(公告)号：US4399818A
公开(公告)日：1983-08-23
申请号：US251192
申请日：1981-04-06
申请人： David K. Money
发明人： David K. Money
CPC分类号： A61N1/365 , A61N1/3716
摘要： There is disclosed a direct-coupled output stage which is especially advantageous for use in an implantable heart pacer. In order to provide for charge balancing at the electrode/electrolyte interfaces, the electrodes are shorted to each other after a pacing pulse is generated. Not only is the use of a bulky coupling capacitor avoided, but the stored charge dissipates in a much shorter time, thereby minimizing the "blind" interval in the sensing cycle.
摘要翻译： 公开了一种直接耦合输出级，其特别有利于在可植入的心脏起搏器中使用。 为了在电极/电解质界面处提供电荷平衡，在产生起搏脉冲之后，电极彼此短路。 避免使用庞大的耦合电容器，但是存储的电荷在更短的时间内消耗，从而最小化感测周期中的“盲”间隔。
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