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1.发明申请In vivo site-sepecific incorporation of N-acetyl-galactosamine amino acids in eubacteria 审中-公开N-乙酰基半乳糖胺氨基酸在真细菌中的体内位点 - 特异性掺入公开(公告)号：US20080241903A1
公开(公告)日：2008-10-02
申请号：US12082214
申请日：2008-04-08
申请人： Peter G. Schultz , Sarah R. Hanson , Ran Xu , Zhiwen Zhang , Chi-Huey Wong
发明人： Peter G. Schultz , Sarah R. Hanson , Ran Xu , Zhiwen Zhang , Chi-Huey Wong
CPC分类号： C12P21/005 , C12N9/93 , C12N15/67
摘要： Methods and compositions for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid having a N-acetylgalactosamine moiety into a protein; optionally, the N-acetylgalactosamine-containing unnatural amino acid can be further modified with additional sugars.
摘要翻译： 提供了体外和体内制备糖蛋白的方法和组合物。 一种方法包括将具有N-乙酰半乳糖胺部分的非天然氨基酸掺入蛋白质中; 任选地，含N-乙酰半乳糖胺的非天然氨基酸可以进一步用另外的糖进行改性。
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2.发明授权In vivo site-specific incorporation of N-acetyl-galactosamine amino acids in eubacteria 失效N-乙酰半乳糖胺氨基酸在真细菌中的体内位点特异性掺入公开(公告)号：US07378263B2
公开(公告)日：2008-05-27
申请号：US11255601
申请日：2005-10-20
申请人： Peter G. Schultz , Sarah R. Hanson , Ran Xu , Zhiwen Zhang , Chi-Heuy Wong
发明人： Peter G. Schultz , Sarah R. Hanson , Ran Xu , Zhiwen Zhang , Chi-Heuy Wong
CPC分类号： C12P21/005 , C12N9/93 , C12N15/67
摘要： Methods and compositions for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid having a N-acetylgalactosamine moiety into a protein; optionally, the N-acetylgalactosamine-containing unnatural amino acid can be further modified with additional sugars.
摘要翻译： 提供了体外和体内制备糖蛋白的方法和组合物。 一种方法包括将具有N-乙酰半乳糖胺部分的非天然氨基酸掺入蛋白质中; 任选地，含N-乙酰半乳糖胺的非天然氨基酸可以进一步用另外的糖进行改性。
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3.发明申请In vivo site-specific incorporation of N-acetyl-galactosamine amino acids in eubacteria 失效N-乙酰半乳糖胺氨基酸在真细菌中的体内位点特异性掺入公开(公告)号：US20060110796A1
公开(公告)日：2006-05-25
申请号：US11255601
申请日：2005-10-20
申请人： Peter Schultz , Sarah Hanson , Ran Xu , Zhiwen Zhang , Chi-Huey Wong
发明人： Peter Schultz , Sarah Hanson , Ran Xu , Zhiwen Zhang , Chi-Huey Wong
CPC分类号： C12P21/005 , C12N9/93 , C12N15/67
摘要： Methods and compositions for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid having a N-acetylgalactosamine moiety into a protein; optionally, the N-acetylgalactosamine-containing unnatural amino acid can be further modified with additional sugars.
摘要翻译： 提供了体外和体内制备糖蛋白的方法和组合物。 一种方法包括将具有N-乙酰半乳糖胺部分的非天然氨基酸掺入蛋白质中; 任选地，含N-乙酰半乳糖胺的非天然氨基酸可以进一步用另外的糖进行改性。
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4.发明申请In Vivo Site-Specific Incorporation of N-Acetyl-Galactosamine Amino Acids in Eubacteria 审中-公开体内位点特异性引入N-乙酰基半乳糖胺氨基酸在细菌中公开(公告)号：US20080064059A1
公开(公告)日：2008-03-13
申请号：US11664898
申请日：2005-10-20
申请人： Peter Schultz , Sarah Hanson , Ran Xu , Zhiwen Zhang , Chi-Huey Wong
发明人： Peter Schultz , Sarah Hanson , Ran Xu , Zhiwen Zhang , Chi-Huey Wong
CPC分类号： C12P21/005 , C12N9/93 , C12N15/67
摘要： Methods and compositions for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid having a N-acetylgalactosamine moiety into a protein; optionally, the N-acetylgalactosamine-containing unnatural amino acid can be further modified with additional sugars.
摘要翻译： 提供了体外和体内制备糖蛋白的方法和组合物。 一种方法包括将具有N-乙酰半乳糖胺部分的非天然氨基酸掺入蛋白质中; 任选地，含N-乙酰半乳糖胺的非天然氨基酸可以进一步用另外的糖进行改性。
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