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1.发明授权Use of PDE 4-specific inhibitors to reduce the severity of a bacterial infection after a respiratory viral infection 失效使用PDE4特异性抑制剂降低呼吸道病毒感染后细菌感染的严重性公开(公告)号：US06436971B2
公开(公告)日：2002-08-20
申请号：US09779401
申请日：2001-02-08
申请人： Peter L. DeMarsh , Susan B. Dillon , Gary Woodnutt
发明人： Peter L. DeMarsh , Susan B. Dillon , Gary Woodnutt
IPC分类号： A01N4340
CPC分类号： A61K31/277 , A61K31/00
摘要： This invention relates to a method for the prophylaxis of or reducing the severity of post-viral bacterial infection by administering a PDE 4-specific inhibitor prior to or during the course of a viral infection or thereafter during the course of the bacterial infection.
摘要翻译： 本发明涉及通过在病毒感染之前或期间或在细菌感染过程之前施用PDE4特异性抑制剂来预防或降低病毒后细菌感染的严重性的方法。
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2.发明授权Apparatus for and a method of severing multiple casing strings using explosives 失效用于使用爆炸物切断多个套管柱的装置和方法
公开(公告)号：US5467824A
公开(公告)日：1995-11-21
申请号：US352910
申请日：1994-12-09
IPC分类号： E21B29/02
CPC分类号： E21B29/02
摘要： A method of and apparatus for severing multiple concentric casing strings in an abandoned oil or gas well allowing the upper portion of the casing strings to be removed comprising positioning a container holding a sealed cylinder full of air at atmospheric pressure that is surrounded by a high velocity explosive in the casing at the location of the desired cut. Igniting the explosive at one end of the container so that the mixture detonates producing a shock wave and gas bubbles that travel downwardly progressively, collapsing the sealed cylinder and increasing the pressure of the air in the cylinder until the cylinder fails whereby pressurized air forced from the cylinder causes the shock wave and gas bubbles from the TNT, RDX, and aluminum mixture to move laterally and sever the casing strings.
摘要翻译： 一种用于在废弃的油或气井中切断多个同心套管柱的方法和装置，其允许去除套管柱的上部，包括定位容纳保持密封的气瓶的容器，该容器在大气压力下被高速包围 在所需切割位置的套管中爆炸。 在容器的一端点燃爆炸物，使得混合物引爆产生冲击波和逐渐向下运动的气泡，使密封的圆柱体折叠并增加气缸中的空气的压力，直到气缸失效，从而迫使压缩空气从 气缸导致来自TNT，RDX和铝混合物的冲击波和气泡横向移动并切断套管柱。
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公开(公告)号：US5479961A
公开(公告)日：1996-01-02
申请号：US352895
申请日：1994-12-09
CPC分类号： F16L13/143 , F16L13/147 , F16L55/11 , F28F11/02 , Y10T29/4994
摘要： A plug for sealing the open end of a tube located in an opening in a tube sheet of a heat exchanger is described along with a method of installing the plug. The plug is comprised of a generally cylindrical metallic body of ductile material that is inserted into the open end of the tube at the tube sheet. The body carries one or more resilient seal rings and has a longitudinally extending blind central opening in the body. A body of pressure transmitting material, such as polyethylene is located in the body and an explosive charge is located in a longitudinally extending central opening in the body of pressure transmitting material. The explosive charge, when detonated, expands the metallic body of the plug and the resilient seal ring into sealing engagement with the tube. A method of plugging a leaky metal tube in a heat exchanger tube bundle and tube sheet structure where the tubes extend through the tube sheet by inserting a metallic plug having an explosive charge inside the plug and a resilient seal on the outside of the plug into the tube and detonating the explosive charge.
摘要翻译： 描述了一种用于密封位于热交换器的管板中的开口中的管的开口端的塞子以及安装插头的方法。 塞子由延伸材料的大致圆柱形的金属体构成，其插入管板的开口端。 身体携带一个或多个弹性密封环，并且在身体中具有纵向延伸的盲中心开口。 诸如聚乙烯的压力传递材料的主体位于主体中，并且爆炸装料位于压力传递材料主体的纵向延伸的中心开口中。 爆炸装置在引爆时，使塞子的金属体和弹性密封环与管道密封接合。 一种将泄漏的金属管堵塞在热交换器管束和管板结构中的方法，其中管子通过插入插塞内具有爆炸物的金属塞和插塞外部的弹性密封件延伸穿过管板 并引爆炸药。
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公开(公告)号：US4654496A
公开(公告)日：1987-03-31
申请号：US598661
申请日：1984-04-11
CPC分类号： B23K35/0216 , B23K9/013
摘要： An improved system for underwater oxy-arc cutting of a work piece, and a unique cutting rod used in such cutting work. This rod has an outer ferrous metal tube which contains a metal liner, which liner may in turn be comprised of a plurality of metal wires spaced in a circular pattern along the inner circumference of the tube. Oxygen is passed through a central passageway within the tube near but less than at sonic flows to avoid arc bounce. DC current (200-400 amperes) flows between the rod and work piece to form an arc consuming the rod at a rate between about 0.09-0.20 inches per second. The cross-sectional areas of the tube and the wires are about equal and the central passageway is less than one-half of either the tube or wires in cross-sectional areas. The rod is made (non-thermic) by sealing the tube about the wires or by use of aluminum or copper wires. Optimized parameters in underwater cutting of the work piece is applied, i.e. cutting rate, oxygen consumption, current magnitude and rod consumption. To minimize the consumption of the cutting rod, a non-thermic rod is used so that, upon arc interruption either no burning or slow burning ensues, even with continued oxygen flow.
摘要翻译： 一种用于工件的水下氧弧切割的改进系统，以及用于这种切割工作中的独特切割杆。 该杆具有含有金属衬垫的外部黑色金属管，该衬里可以依次沿着管的内圆周以圆形图案间隔开的多个金属线组成。 氧气穿过管内的中心通道，但低于声流，以避免电弧反弹。 直流电流（200-400安培）在杆和工件之间流动以形成以约0.09-0.20英寸/秒的速率消耗棒的电弧。 管和电线的横截面面积大致相等，中心通道小于横截面积的管或电线的二分之一。 杆通过围绕导线密封管或通过使用铝或铜线制成（非热）。 应用工件水下切割中的优化参数，即切割速率，耗氧量，电流量级和棒消耗。 为了最小化切割杆的消耗，使用非热棒，使得在电弧中断时，即使持续的氧气流也不会发生燃烧或缓慢燃烧。
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