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公开(公告)号：US20080213264A1
公开(公告)日：2008-09-04
申请号：US11929668
申请日：2007-10-30
Applicant: Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
Inventor： Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
IPC: A61K39/00
CPC classification number: C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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公开(公告)号：US06555115B1
公开(公告)日：2003-04-29
申请号：US09410568
申请日：1999-10-01
Applicant: Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky , Shyian Jen , Erika Jean Stromberg
Inventor： Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky , Shyian Jen , Erika Jean Stromberg
IPC: A61K39118
CPC classification number: C07K14/295 , A61K39/00 , A61K2039/51 , C07K2319/00
Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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3.发明授权公开(公告)号：US07462357B2
公开(公告)日：2008-12-09
申请号：US10872155
申请日：2004-06-18
Applicant: Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
Inventor： Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
IPC: A61K39/00 , A61K39/38 , A61K39/02 , A61K39/118 , A61K38/00 , C07K1/00 , C07K14/00 , C07K17/00 , A01N37/18
CPC classification number: C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
Abstract translation: 公开了用于诊断和治疗衣原体感染的化合物和方法。 提供的化合物包括含有衣原体抗原的至少一个抗原部分的多肽和编码这些多肽的DNA序列。 还提供了包含此类多肽或DNA序列的药物组合物和疫苗以及针对这些多肽的抗体。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的衣原体感染。
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4.发明授权公开(公告)号：US06375955B1
公开(公告)日：2002-04-23
申请号：US09022765
申请日：1998-02-12
Applicant: Steven G. Reed , Antonio Campos-Neto , John R. Webb , Davin C. Dillon , Yasir A. W. Skeiky , Ajay Bhatia , Peter Probst
Inventor： Steven G. Reed , Antonio Campos-Neto , John R. Webb , Davin C. Dillon , Yasir A. W. Skeiky , Ajay Bhatia , Peter Probst
IPC: A61K39008
CPC classification number: C07K14/44 , A61K38/00 , A61K39/00 , A61K2039/51 , Y02A50/41
Abstract: Compositions and methods for preventing, treating and detecting leishmaniasis and stimulating immune responses in patients are disclosed. The compounds provided include polypeptides that contain at least an immunogenic portion of one or more Leishmania antigens, or a variant thereof. Vaccines and pharmaceutical compositions comprising such polypeptides, or DNA molecules encoding such polypeptides, are also provided and may be used, for example, for the prevention and therapy of leishmaniasis, as well as for the detection of Leishmania infection.
Abstract translation: 公开了用于预防，治疗和检测利什曼病并刺激患者免疫应答的组合物和方法。 提供的化合物包括含有至少一种或多种利什曼原虫抗原的免疫原性部分或其变体的多肽。 还提供包含这些多肽的疫苗和药物组合物，或编码这些多肽的DNA分子，并且可以用于例如预防和治疗利什曼病以及利什曼原虫感染的检测。
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5.发明授权Compounds and methods for the treatment and diagnosis of chlamydial infection 失效用于治疗和诊断衣原体感染的化合物和方法
公开(公告)号：US6166177A
公开(公告)日：2000-12-26
申请号：US208277
申请日：1998-12-08
Applicant: Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky
Inventor： Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky
CPC classification number: C07K14/295 , A61K39/00 , A61K2039/51 , C07K2319/00 , Y10S530/82 , Y10S530/825
Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydial antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
Abstract translation: 公开了用于诊断和治疗衣原体感染的化合物和方法。 提供的化合物包括含有衣原体抗原的至少一个抗原部分的多肽和编码这些多肽的DNA序列。 还提供了包含此类多肽或DNA序列的药物组合物和疫苗以及针对这些多肽的抗体。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的衣原体感染。
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Patent Agency Ranking
公开(公告)号：US20090035296A1
公开(公告)日：2009-02-05
申请号：US11929672
申请日：2007-10-30
Applicant: Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
Inventor： Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
IPC: A61K39/395 , C07H21/04 , C07K14/435 , C07K16/00 , C12N15/63 , A61P31/04 , A61K35/12 , C12N5/00 , G01N33/53 , C12N5/08
CPC classification number: C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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公开(公告)号：US20080181918A1
公开(公告)日：2008-07-31
申请号：US11929620
申请日：2007-10-30
Applicant: Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
Inventor： Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
CPC classification number: C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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公开(公告)号：US06432916B1
公开(公告)日：2002-08-13
申请号：US09556877
申请日：2000-04-19
Applicant: Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky , Steven P. Fling
Inventor： Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky , Steven P. Fling
IPC: A61K3800
CPC classification number: C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/51 , C07K2319/00 , Y10S435/975
Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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9.发明授权公开(公告)号：US08052975B2
公开(公告)日：2011-11-08
申请号：US11929665
申请日：2007-10-30
Applicant: Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
Inventor： Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
IPC: A61K39/00 , A61K39/38 , A61K39/02 , A61K39/118 , A61K45/00 , A61K38/00 , C07K14/00 , C07K16/00 , C07K17/00 , C07K2/00 , C07K4/00 , C07K5/00 , C07K7/00 , C07K1/00
CPC classification number: C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
Abstract translation: 公开了用于诊断和治疗衣原体感染的化合物和方法。 提供的化合物包括含有衣原体抗原的至少一个抗原部分的多肽和编码这些多肽的DNA序列。 还提供了包含此类多肽或DNA序列的药物组合物和疫苗以及针对这些多肽的抗体。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的衣原体感染。
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公开(公告)号：US06447779B1
公开(公告)日：2002-09-10
申请号：US09288594
申请日：1999-04-08
Applicant: Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky , Steven P. Fling
Inventor： Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky , Steven P. Fling
IPC: A61K3902
CPC classification number: C07K14/295 , A61K39/00 , A61K2039/51 , C07K2319/00
Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
Abstract translation: 公开了用于诊断和治疗衣原体感染的化合物和方法。 提供的化合物包括含有衣原体抗原的至少一个抗原部分的多肽和编码这些多肽的DNA序列。 还提供了包含此类多肽或DNA序列的药物组合物和疫苗以及针对这些多肽的抗体。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的衣原体感染。
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