-
公开(公告)号：US10550200B2
公开(公告)日：2020-02-04
申请号：US15239556
申请日：2016-08-17
Applicant: Pfizer Inc.
Inventor： Debra Pittman , James R. Apgar , Zong Sean Juo , Macy Jin , Mark Stahl , Gregory J. Carven , Matthew Holsti , Susan Benard , Sunita R. Hett , Reema Jasuja
IPC: C07K16/38 , A61K38/48 , A61K39/395 , A61K39/00
Abstract: The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful for treating bleeding disorders and shortening clotting time.
-
公开(公告)号：US20230416405A1
公开(公告)日：2023-12-28
申请号：US18182619
申请日：2023-03-13
Applicant: Pfizer Inc.
Inventor： Debra Pittman , James R. Apgar , Zong Sean Juo , Macy Jin , Mark Stahl , Gregory J. Carven , Matthew Holsti , Susan Benard , Sunita R. Hett , Reema Jasuja
IPC: C07K16/38 , A61K39/00 , A61K38/48 , A61K39/395
CPC classification number: C07K16/38 , A61K39/0011 , A61K38/4846 , A61K39/3955 , C12Y304/21021 , A61K2039/505 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/76 , C07K2317/92 , C07K2317/21 , A61K2039/5158 , A61K2039/55522 , C07K2317/565 , C07K2317/622
Abstract: The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful for treating bleeding disorders and shortening clotting time.
-
公开(公告)号：US20210196823A1
公开(公告)日：2021-07-01
申请号：US17250083
申请日：2019-06-06
Applicant: Pfizer Inc.
Inventor： Alexander Hal Drakesmith , João André Traila Arezes , Simon John Draper , Kirsty Anne McHugh , Fredrik Karpe , Nathan Denton , Orla Cunningham , Niall John Foy , Reema Jasuja
IPC: A61K39/395 , C07K16/26 , C07K16/24 , A61K45/06 , A61K31/426 , A61K31/522 , A61K31/366 , A61K31/4985 , A61K38/28 , A61P1/16 , A61P3/04 , A61P3/10
Abstract: The present invention further relates to methods for treating a disease of iron metabolism and disease of fat or carbohydrate metabolism using a BMP agonist or antagonist
-
公开(公告)号：US11634504B2
公开(公告)日：2023-04-25
申请号：US17102883
申请日：2020-11-24
Applicant: Pfizer Inc.
Inventor： Debra Pittman , James R. Apgar , Zong Sean Juo , Macy Jin , Mark Stahl , Gregory J. Carven , Matthew Holsti , Susan Benard , Sunita R. Hett , Reema Jasuja
IPC: C07K16/38 , A61K39/00 , A61K38/48 , A61K39/395
Abstract: The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful for treating bleeding disorders and shortening clotting time.
-
Patent Agency Ranking
公开(公告)号：US20170073428A1
公开(公告)日：2017-03-16
申请号：US15239556
申请日：2016-08-17
Applicant: Pfizer Inc.
Inventor： Debra Pittman , James R. Apgar , Zong Sean Juo , Macy Jin , Mark Stahl , Gregory J. Carven , Matthew Holsti , Susan Benard , Sunita R. Hett , Reema Jasuja
IPC: C07K16/38 , A61K38/48 , A61K39/395
Abstract: The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful for treating bleeding disorders and shortening clotting time.
Abstract translation: 本发明涉及特异性结合TFPI并抑制其活性的抗体及其抗原结合片段。 这样的抗体和片段可用于治疗出血性疾病和缩短凝血时间。
-
公开(公告)号：US12168698B2
公开(公告)日：2024-12-17
申请号：US18182619
申请日：2023-03-13
Applicant: Pfizer Inc.
Inventor： Debra Pittman , James R. Apgar , Zong Sean Juo , Macy Jin , Mark Stahl , Gregory J. Carven , Matthew Holsti , Susan Benard , Sunita R. Hett , Reema Jasuja
IPC: C07K16/38 , A61K38/48 , A61K39/00 , A61K39/395
Abstract: The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful for treating bleeding disorders and shortening clotting time.
-
公开(公告)号：US20210101998A1
公开(公告)日：2021-04-08
申请号：US17102883
申请日：2020-11-24
Applicant: Pfizer Inc.
Inventor： Debra Pittman , James R. Apgar , Zong Sean Juo , Macy Jin , Mark Stahl , Gregory J. Carven , Matthew Holsti , Susan Benard , Sunita R. Hett , Reema Jasuja
IPC: C07K16/38 , A61K39/00 , A61K39/395 , A61K38/48
Abstract: The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful for treating bleeding disorders and shortening clotting time.
-
公开(公告)号：US20190231856A1
公开(公告)日：2019-08-01
申请号：US16157194
申请日：2018-10-11
Applicant: PFIZER INC.
Inventor： Steven Arkin , Marcus Carr , Joachim Fruebis , Sunita Hett , Reema Jasuja , Debra Pittman
IPC: A61K38/48
CPC classification number: A61K38/4846 , C12Y304/21006
Abstract: The disclosure provides compositions and methods for treating or preventing intracerebral hemorrhage (ICH) in a subject by administering a variant of FXa.
-
公开(公告)号：US20160375109A1
公开(公告)日：2016-12-29
申请号：US15112088
申请日：2015-01-15
Applicant: PFIZER INC.
Inventor： Steven Arkin , Marcus Carr , Joachim Fruebis , Sunita Hett , Reema Jasuja , Debra Pittman
IPC: A61K38/48
CPC classification number: A61K38/4846 , C12Y304/21006
Abstract: The disclosure provides compositions and methods for treating or preventing intracerebral hemorrhage (ICH) in a subject by administering a variant of FXa.
Abstract translation: 本公开提供了通过施用FXa的变体来治疗或预防受试者脑内出血（ICH）的组合物和方法。
-
-
-
-
-
-
-
-
Search Results
9
records
(took 0.014 seconds)
