公开(公告)号：US09902691B2

公开(公告)日：2018-02-27

申请号：US15030563

申请日：2014-10-28

Applicant: Pfizer Inc.

Inventor： Robert Wayne Dugger ,  Leo Joseph Letendre ,  Vimalkumar Babubhai Patel ,  Amarnauth Shastrie Prashad ,  Chunchun Zhang

IPC: C07C323/48 ,  C07C319/20 ,  C07C319/28 ,  C07C319/06 ,  C07C323/60 ,  C07D207/46 ,  C07H1/06 ,  C07H15/26 ,  A61K47/68

CPC classification number: C07C323/48 ,  A61K47/6809 ,  C07C319/06 ,  C07C319/20 ,  C07C319/28 ,  C07C323/60 ,  C07D207/46 ,  C07H1/06 ,  C07H15/26

Abstract: The present invention relates to intermediates of Formula I and to methods of synthesizing and purifying calicheamicin derivatives.

公开(公告)号：US20160251389A1

公开(公告)日：2016-09-01

申请号：US15030563

申请日：2014-10-28

Applicant: Pfizer Inc.

Inventor： Robert Wayne Dugger ,  Leo Joseph Letendre ,  Vimalkumar Babubhai Patel ,  Amarnauth Shastrie Prashad ,  Chunchun Zhang

IPC: C07H15/26 ,  C07C319/06 ,  C07C319/20 ,  A61K47/48 ,  C07H1/06 ,  C07C323/60 ,  C07D207/46

CPC classification number: C07C323/48 ,  A61K47/6809 ,  C07C319/06 ,  C07C319/20 ,  C07C319/28 ,  C07C323/60 ,  C07D207/46 ,  C07H1/06 ,  C07H15/26

Abstract: The present invention relates to intermediates of Formula I and to methods of synthesizing and purifying calicheamicin derivatives.

Abstract translation: 本发明涉及式I的中间体以及合成和提纯加利车霉素衍生物的方法。

公开(公告)号：US10508081B2

公开(公告)日：2019-12-17

申请号：US15870014

申请日：2018-01-12

Applicant: PFIZER INC.

Inventor： Robert Wayne Dugger ,  Leo Joseph Letendre ,  Vimalkumar Babubhai Patel ,  Amarnauth Shastrie Prashad ,  Chunchun Zhang

IPC: C07C323/48 ,  C07C319/20 ,  C07C323/60 ,  C07C319/28 ,  A61K47/68 ,  C07C319/06 ,  C07D207/46 ,  C07H1/06 ,  C07H15/26

Abstract: The present invention relates to intermediates of Formula I and to methods of synthesizing and purifying calicheamicin derivatives.

公开(公告)号：US20180134656A1

公开(公告)日：2018-05-17

申请号：US15870014

申请日：2018-01-12

Applicant: PFIZER INC.

Inventor： Robert Wayne Dugger ,  Leo Joseph Letendre ,  Vimalkumar Babubhai Patel ,  Amarnauth Shastrie Prashad ,  Chunchun Zhang

IPC: C07C323/48 ,  C07C323/60 ,  C07C319/20 ,  C07D207/46 ,  C07C319/28 ,  C07C319/06 ,  C07H1/06 ,  C07H15/26

Abstract: The present invention relates to intermediates of Formula I and to methods of synthesizing and purifying calicheamicin derivatives.