公开(公告)号：US09199009B2

公开(公告)日：2015-12-01

申请号：US13217116

申请日：2011-08-24

申请人： Robert Krensky ,  David G. Matsuura ,  Philip J. Simpson

发明人： Robert Krensky ,  David G. Matsuura ,  Philip J. Simpson

IPC分类号： A61M1/00 ,  A61M1/02 ,  A61M1/36

CPC分类号： A61M1/0001 ,  A61M1/0009 ,  A61M1/0281 ,  A61M1/3627 ,  Y10T137/8593

摘要： A method for recovering blood from a blood-laden surgical sponge for autologous reinfusion, the method comprising the steps of: conveying negative pressure to a housing with the blood-laden surgical sponge; applying a predetermined force to draw the blood from the surgical sponge; and collecting the recovered blood.

摘要翻译： 一种用于从用于自体回输的血液充填的外科海绵中回收血液的方法，所述方法包括以下步骤：用含血的手术海绵将负压输送到外壳; 施加预定的力以从手术海绵中抽取血液; 并收集回收的血液。

公开(公告)号：US08696751B2

公开(公告)日：2014-04-15

申请号：US12787281

申请日：2010-05-25

申请人： John E. Ashley ,  Philip J. Simpson ,  Walter Dean Gillespie ,  Damien J. Shulock ,  Murali Kadaba ,  David G. Matsuura ,  George A. Mansfield, III ,  Thomas Grotz ,  Rudy Pretti

发明人： John E. Ashley ,  Philip J. Simpson ,  Walter Dean Gillespie ,  Damien J. Shulock ,  Murali Kadaba ,  David G. Matsuura ,  George A. Mansfield, III ,  Thomas Grotz ,  Rudy Pretti

IPC分类号： A61F2/44

CPC分类号： A61F2/441 ,  A61F2/30742 ,  A61F2/442 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/30079 ,  A61F2002/3008 ,  A61F2002/30133 ,  A61F2002/30365 ,  A61F2002/30405 ,  A61F2002/30476 ,  A61F2002/30484 ,  A61F2002/30499 ,  A61F2002/30505 ,  A61F2002/30514 ,  A61F2002/30522 ,  A61F2002/30525 ,  A61F2002/3055 ,  A61F2002/30551 ,  A61F2002/30565 ,  A61F2002/30579 ,  A61F2002/30581 ,  A61F2002/30589 ,  A61F2002/30601 ,  A61F2002/30841 ,  A61F2002/482 ,  A61F2002/485 ,  A61F2210/009 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2230/0015 ,  A61F2250/0007 ,  A61F2250/0069 ,  A61F2250/0098 ,  A61F2310/00017 ,  A61F2310/00023

摘要： A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a refracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. The implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system having a plurality of linked locking elements that work in unison to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning.

摘要翻译： 脊柱植入物，其构造成部署在相邻的椎体之间。 植入物具有至少一个具有折射构造的可延伸的支撑元件，以便于植入物的展开和延伸的构造，以便扩大植入物并有效地分散椎间盘空间，稳定运动节段并消除病理脊柱运动。 植入物在其未展开状态下具有小于其通常通过的神经孔的尺寸的最小尺寸，以被部署在椎间空间内。 植入物具有锁定系统，该锁定系统具有多个连接的锁定元件，其一致地工作以将植入物锁定在延伸构造中。 也可以提供骨接合锚，以确保安全的定位。

公开(公告)号：US08435296B2

公开(公告)日：2013-05-07

申请号：US12548260

申请日：2009-08-26

申请人： Murali Kadaba ,  Philip J. Simpson ,  John E. Ashley ,  Walter Dean Gillespie ,  Thomas Grotz ,  George A. Mansfield, III ,  David G. Matsuura ,  Rudy Pretti

发明人： Murali Kadaba ,  Philip J. Simpson ,  John E. Ashley ,  Walter Dean Gillespie ,  Thomas Grotz ,  George A. Mansfield, III ,  David G. Matsuura ,  Rudy Pretti

IPC分类号： A61F2/44

CPC分类号： A61F2/44 ,  A61F2/30742 ,  A61F2/442 ,  A61F2/4455 ,  A61F2002/30079 ,  A61F2002/3008 ,  A61F2002/30133 ,  A61F2002/30365 ,  A61F2002/30405 ,  A61F2002/30476 ,  A61F2002/30484 ,  A61F2002/30499 ,  A61F2002/30505 ,  A61F2002/30514 ,  A61F2002/30522 ,  A61F2002/30525 ,  A61F2002/3055 ,  A61F2002/30579 ,  A61F2002/30581 ,  A61F2002/30589 ,  A61F2002/30601 ,  A61F2002/30841 ,  A61F2002/482 ,  A61F2002/485 ,  A61F2210/009 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2230/0015 ,  A61F2250/0007 ,  A61F2250/0069 ,  A61F2250/0098 ,  A61F2310/00017 ,  A61F2310/00023

摘要： A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning.

公开(公告)号：US08192495B2

公开(公告)日：2012-06-05

申请号：US12384622

申请日：2009-04-07

申请人： Philip J. Simpson ,  David G. Matsuura ,  Walter Dean Gillespie ,  George A. Mansfield, III ,  John E. Ashley

发明人： Philip J. Simpson ,  David G. Matsuura ,  Walter Dean Gillespie ,  George A. Mansfield, III ,  John E. Ashley

IPC分类号： A61F2/44

CPC分类号： A61F2/44 ,  A61F2/30742 ,  A61F2/442 ,  A61F2/4455 ,  A61F2002/30079 ,  A61F2002/3008 ,  A61F2002/30133 ,  A61F2002/30365 ,  A61F2002/30405 ,  A61F2002/30476 ,  A61F2002/30484 ,  A61F2002/30499 ,  A61F2002/30505 ,  A61F2002/30514 ,  A61F2002/30522 ,  A61F2002/30525 ,  A61F2002/3055 ,  A61F2002/30579 ,  A61F2002/30581 ,  A61F2002/30589 ,  A61F2002/30601 ,  A61F2002/30841 ,  A61F2002/482 ,  A61F2002/485 ,  A61F2210/009 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2230/0015 ,  A61F2250/0007 ,  A61F2250/0069 ,  A61F2250/0098 ,  A61F2310/00017 ,  A61F2310/00023

摘要： A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration.

摘要翻译： 脊柱植入物，其构造成部署在相邻的椎体之间。 植入物具有至少一个具有缩回构型的可延伸的支撑元件，以便于植入物的展开和延伸构造，以便扩大植入物并有效地分散椎间盘空间，稳定运动节段并消除病理脊柱运动。 角度畸形也可以被修正，自然曲率恢复。 优选地，植入物在其未展开状态下具有小于其通常通过以在椎间空间内展开的神经孔的尺寸的最小尺寸。 植入物设置有锁定系统，优选地具有多个锁定元件以将植入物锁定在延伸构造中。

公开(公告)号：US06402839B1

公开(公告)日：2002-06-11

申请号：US09294529

申请日：1999-04-19

申请人： Daniel L. Meier ,  Gregory T. Neugebauer ,  Edward V. Macuga ,  Robert P. Stoehr ,  Philip J. Simpson ,  Jalal Salami

发明人： Daniel L. Meier ,  Gregory T. Neugebauer ,  Edward V. Macuga ,  Robert P. Stoehr ,  Philip J. Simpson ,  Jalal Salami

IPC分类号： C30B1534

CPC分类号： C30B15/26 ,  C30B15/007 ,  C30B15/22 ,  C30B15/305 ,  Y10S117/903 ,  Y10T117/1032

摘要： A process for dendritic web growth is described. The process includes providing a melt, growing a dendritic web crystal from the melt, replenishing the melt during the step of growing the dendritic web crystal, and applying a magnetic field to the melt during the step of growing the dendritic web crystal. An apparatus for stabilizing dendritic web growth is also described. The apparatus includes a crucible including a feed compartment for receiving pellets to facilitate melt replenishment and a growth compartment designed to hold a melt for dendritic web growth. The apparatus further includes a magnetic field generator configured to provide a magnetic field during dendritic web growth.

摘要翻译： 描述了树枝状网生长的方法。 该方法包括提供熔体，从熔体中生长树枝状网状晶体，在生长树枝状晶体晶体的步骤期间补充熔体，以及在生长树枝状晶体晶体的步骤期间向熔体施加磁场。 还描述了用于稳定树枝状网生长的装置。 该装置包括坩埚，其包括用于接收颗粒以促进熔体补充的进料室和设计成保持用于树枝状网幅生长的熔体的生长室。 该装置还包括磁场发生器，其被配置为在树突纤维网生长期间提供磁场。

公开(公告)号：US6149607A

公开(公告)日：2000-11-21

申请号：US128882

申请日：1998-08-04

申请人： Philip J. Simpson ,  David G. Matsuura ,  John Kilcoyne

发明人： Philip J. Simpson ,  David G. Matsuura ,  John Kilcoyne

IPC分类号： A61B10/00 ,  A61B10/06 ,  A61B17/28 ,  A61B17/32

CPC分类号： A61B10/06 ,  A61B2017/2926 ,  A61B2017/2933 ,  A61B2017/2939 ,  A61B2017/294 ,  A61B2017/320064

摘要： A biopsy device for acquiring more than one tissue sample comprises an elongated, flexible actuator shaft which is slidable within an outer sleeve. A jaw portion is coupled to the actuator shaft and the outer sleeve in such a manner as to open when the shaft is moved in a first direction relative to the sleeve and close when the shaft is moved in a second direction relative to the sleeve.

摘要翻译： 用于采集多于一个组织样本的活检装置包括可在外套筒内滑动的细长的柔性致动器轴。 当轴沿相对于套筒的第一方向移动并且当轴相对于套筒沿第二方向移动时，钳口部分以这样的方式联接到致动器轴和外套筒，以便打开。

公开(公告)号：US08636689B2

公开(公告)日：2014-01-28

申请号：US12669255

申请日：2008-07-16

申请人： Reynaldo B. Halili, Jr. ,  Victor Wei-Chung Chang ,  Phillip A. Estepa ,  Tyler J. Holschlag ,  Philip J. Simpson ,  David G. Matsuura

发明人： Reynaldo B. Halili, Jr. ,  Victor Wei-Chung Chang ,  Phillip A. Estepa ,  Tyler J. Holschlag ,  Philip J. Simpson ,  David G. Matsuura

IPC分类号： A61M37/00

CPC分类号： A61M5/24 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2075 ,  A61J1/2096 ,  A61M5/2448 ,  A61M2206/16

摘要： Pen injection devices (10) and methods of using a pen injection device are disclosed. Pen injection devices include a sterile dual transfer spike assembly (150) including a dual transfer spike defining a fluidic pathway; a first cartridge assembly (12) including a first cartridge (20) containing a first substance; a second cartridge assembly (14) including a second cartridge (30) containing a second substance; a plunger rod (50) translatable in a first direction; and a biasing mechanism (60) configured to bias the plunger rod in a second direction opposite the first direction. Methods of using a pen injection device having a first container, a second container, a plunger rod, and a biasing mechanism include activating the pen injection device, thereby creating a fluidic pathway between the first container and the second container; and translating the plunger rod at least once, thereby transferring a first substance from one container to the other container to mix with a second substance.

摘要翻译： 公开了笔注射装置（10）和使用笔式注射装置的方法。 笔注射装置包括无菌双转移钉组件（150），其包括限定流体通路的双转移尖峰; 第一盒组件（12），包括容纳第一物质的第一盒（20）; 第二盒组件（14），包括容纳第二物质的第二盒（30）; 可在第一方向上平移的柱塞杆（50） 以及偏置机构（60），其构造成沿与第一方向相反的第二方向偏压柱塞杆。 使用具有第一容器，第二容器，柱塞杆和偏置机构的笔式注射装置的方法包括启动笔式注射装置，从而在第一容器和第二容器之间形成流体通路; 并且将所述柱塞杆翻转至少一次，从而将第一物质从一个容器转移到另一容器以与第二物质混合。

公开(公告)号：US08512394B2

公开(公告)日：2013-08-20

申请号：US12843838

申请日：2010-07-26

申请人： Eric V. Schmid ,  Andrew Morris ,  John Nguyen ,  Robert F. Eisele ,  Steven C. Howard ,  Orlando M. Padilla ,  Philip J. Simpson

发明人： Eric V. Schmid ,  Andrew Morris ,  John Nguyen ,  Robert F. Eisele ,  Steven C. Howard ,  Orlando M. Padilla ,  Philip J. Simpson

IPC分类号： A61F2/82

CPC分类号： A61F2/92 ,  A61F2/01 ,  A61F2/07 ,  A61F2/856 ,  A61F2/958 ,  A61F2002/075

摘要： An intraluminal, balloon expandable stent for implantation in a body lumen is disclosed. The present invention provides a lumen support stent with an unobstructed through-lumen for use in a blood vessel. A constraining mechanism is provided for securely maintaining the stent in the collapsed condition during delivery. The stent is preferably formed with a series of interconnected slide and lock mechanisms for permitting movement from a collapsed condition to an expanded condition and inhibiting radial recoil from the expanded condition. The stent may be formed from a shape memory alloy for providing crush-recovery after deployment.

摘要翻译： 公开了一种用于植入体腔的管腔内球囊扩张支架。 本发明提供一种具有用于血管的通畅通管的管腔支架。 提供约束机构用于在输送期间将支架牢固地保持在折叠状态。 支架优选地形成有一系列互连的滑动和锁定机构，用于允许从折叠状态移动到扩张状态，并且抑制从膨胀状态的径向反冲。 支架可以由形状记忆合金形成，用于在展开后提供压碎恢复。

公开(公告)号：US08292944B2

公开(公告)日：2012-10-23

申请号：US11016269

申请日：2004-12-17

申请人： Eric V. Schmid ,  John D. Nguyen ,  Steven C. Howard ,  Orlando M. Padilla ,  Andrew Morris ,  Robert F. Eisele ,  Joseph Anthony DiPari ,  David G. Matsuura ,  Philip J. Simpson ,  Walter D. Gillespie ,  Daniel Moore ,  Thomas R. Jackson ,  Joan Zeltinger ,  Keith Allen Esser ,  Donald K. Brandom

发明人： Eric V. Schmid ,  John D. Nguyen ,  Steven C. Howard ,  Orlando M. Padilla ,  Andrew Morris ,  Robert F. Eisele ,  Joseph Anthony DiPari ,  David G. Matsuura ,  Philip J. Simpson ,  Walter D. Gillespie ,  Daniel Moore ,  Thomas R. Jackson ,  Joan Zeltinger ,  Keith Allen Esser ,  Donald K. Brandom

IPC分类号： A61F2/82

CPC分类号： A61F2/82 ,  A61F2/92 ,  A61F2/93 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0058 ,  B33Y80/00

摘要： The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.

公开(公告)号：US20120215200A1

公开(公告)日：2012-08-23

申请号：US13499251

申请日：2010-10-06

申请人： David G. Matsuura ,  Philip J. Simpson ,  Helen Anderson

发明人： David G. Matsuura ,  Philip J. Simpson ,  Helen Anderson

IPC分类号： A61M5/315 ,  A61M5/145

CPC分类号： A61M5/14216 ,  A61M5/1422 ,  A61M5/16809 ,  A61M5/3129 ,  A61M5/31511 ,  A61M2005/31598

摘要： A precision syringe (10) can comprise an annular fluid pathway (16) and annular plunger (12) sealing received within the annular fluid pathway. Various precision pumps (50, 200, 300, 400, 500, 600, 700, 800, 900, 1000, 1100, 1200, 1300, 1400, 1500, 1600, 1700) are configured for discrete displacement of precise volumes of fluid. The precision pumps can operate by reciprocating movement to expand and contract a cavity (204, 304, 404, 504, 604, 704, 804, 904, 1040, 1104, 1204, 1304, 1404, 1504, 1604, 1704). Fluid can be introduced by movement along an axis or rotation about an axis of one or members forming, in whole or in part, the cavity. Associated methods are also disclosed.

摘要翻译： 精密注射器（10）可以包括环形流体通道（16）和密封在环形流体通路内的环形柱塞（12）。 各种精密泵（50,200,300,400,500,600,700,800,900,1000,1100,1200,1300,1400,1500,1600,1700）被配置用于精确体积的流体的离散位移。 精密泵可以通过往复运动来操作，以膨胀和收缩空腔（204,304,404,504,604,704,804,904,1040,1104,1404,1404,1404,1504,1404,1404）。 流体可以通过沿着轴线的运动或围绕一个或多个部件的轴线的旋转而被引入，整体或部分地形成空腔。 还公开了相关方法。