公开(公告)号：US20240326012A1

公开(公告)日：2024-10-03

申请号：US18623906

申请日：2024-04-01

Applicant: Pierce Biotechnology, Inc.

Inventor： Ramesh Ganapathy ,  Christopher Etienne ,  Deven Etnyre ,  Ashok Salunkhe ,  Atul Deshpande

IPC: B01J20/24 ,  B01D15/34 ,  B01J20/30 ,  C07K1/14

CPC classification number: B01J20/24 ,  B01D15/34 ,  B01J20/3042 ,  C07K1/14

Abstract: The present specification relates to compositions, devices, apparatus, methods, kits and systems for sample preparation (e.g., separation, reduction or removal of small molecules from biomolecules in a sample). Exemplary small molecules that can be separated, reduced or removed have a molecular weight range of

公开(公告)号：US20240091742A1

公开(公告)日：2024-03-21

申请号：US18229553

申请日：2023-08-02

Applicant: Pierce Biotechnology Inc.

Inventor： Ramesh Ganapathy ,  Brendon Wang ,  Ashok Salunkhe ,  Deven Etnyre ,  Barbara Kaboord

IPC: B01J20/288 ,  C07K16/06 ,  B01D15/34 ,  B01D15/38 ,  B01J20/24 ,  B01J20/26 ,  B01J20/30 ,  B01J20/32

CPC classification number: B01J20/288 ,  C07K16/065 ,  B01D15/34 ,  B01D15/3847 ,  B01J20/24 ,  B01J20/267 ,  B01J20/3085 ,  B01J20/3212 ,  B01J20/3293 ,  B01J20/3219 ,  B01J20/3282 ,  B01J20/3248 ,  B01J2220/54

Abstract: Disclosed herein are embodiments of matrixes made of a porous size exclusion support and a cationic moiety for separating one or more small molecules from one or more large molecules in a sample using differences in one or more properties such as the size of the molecules, charge of the molecules, the isoelectric point (pI) of the molecules, and/or any combination of these properties including methods, systems, and kit embodiments. Also disclosed herein are embodiments of a method of making the matrixes and using the matrixes for separating small molecules from one or more large molecules in a sample.

公开(公告)号：US11975306B2

公开(公告)日：2024-05-07

申请号：US17016140

申请日：2020-09-09

Applicant: PIERCE BIOTECHNOLOGY, INC.

Inventor： Ramesh Ganapathy ,  Christopher Etienne ,  Deven Etnyre ,  Ashok Salunkhe ,  Atul Deshpande

IPC: B01J20/24 ,  B01D15/34 ,  B01J20/30 ,  C07K1/14

CPC classification number: B01J20/24 ,  B01D15/34 ,  B01J20/3042 ,  C07K1/14

Abstract: The present specification relates to compositions, devices, apparatus, methods, kits and systems for sample preparation (e.g., separation, reduction or removal of small molecules from biomolecules in a sample). Exemplary small molecules that can be separated, reduced or removed have a molecular weight range of