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1.发明申请Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents 失效二萜类化合物，其组合物及其作为抗癌剂或抗真菌剂的用途公开(公告)号：US20050070540A1
公开(公告)日：2005-03-31
申请号：US10725629
申请日：2003-12-01
申请人： Pierre Beauparlant , Giorgio Attardo , Zhiying Zhang , Angela Stafford , Rosa Ubillas , James McAlpine , Jean-Francois Lavallee , Samuel Fortin , Sasmita Tripathy
发明人： Pierre Beauparlant , Giorgio Attardo , Zhiying Zhang , Angela Stafford , Rosa Ubillas , James McAlpine , Jean-Francois Lavallee , Samuel Fortin , Sasmita Tripathy
IPC分类号： A61P35/00 , C07C45/29 , C07C49/755 , C07C69/00 , A61K31/53 , A61K31/473 , A61K31/498 , A61K31/519
CPC分类号： C07C69/757 , C07C45/292 , C07C49/755 , C07C2603/26
摘要： The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.
摘要翻译： 本发明涉及二萜化合物，包含有效量的二萜化合物的组合物和可用于治疗或预防癌症或肿瘤性疾病的方法，其包括施用有效量的二萜化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，或用于诱导癌症或肿瘤细胞中的凋亡。 本发明的化合物，组合物和方法还可用于治疗或预防真菌感染。 本发明的化合物，组合物和方法也可用于抑制真菌的生长。
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2.发明授权Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents 失效二萜类化合物，其组合物及其作为抗癌剂或抗真菌剂的用途公开(公告)号：US07217844B2
公开(公告)日：2007-05-15
申请号：US10725629
申请日：2003-12-01
申请人： Pierre Beauparlant , Giorgio Attardo , Zhiying Zhang , Angela M. Stafford , Rosa Ubillas , James B. McAlpine , Jean-Francois Lavallee , Samuel Fortin , Sasmita Tripathy
发明人： Pierre Beauparlant , Giorgio Attardo , Zhiying Zhang , Angela M. Stafford , Rosa Ubillas , James B. McAlpine , Jean-Francois Lavallee , Samuel Fortin , Sasmita Tripathy
IPC分类号： C07C43/162 , C07C43/164 , C07C43/166 , C07C49/225 , C07D237/36 , C07D239/70 , A61K31/53 , A61K31/519 , A61K31/498 , A61K31/473 , A61P35/00
CPC分类号： C07C69/757 , C07C45/292 , C07C49/755 , C07C2603/26
摘要： The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.
摘要翻译： 本发明涉及二萜化合物，包含有效量的二萜化合物的组合物和可用于治疗或预防癌症或肿瘤性疾病的方法，其包括施用有效量的二萜化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，或用于诱导癌症或肿瘤细胞中的凋亡。 本发明的化合物，组合物和方法还可用于治疗或预防真菌感染。 本发明的化合物，组合物和方法也可用于抑制真菌的生长。
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3.发明授权公开(公告)号：US07230139B2
公开(公告)日：2007-06-12
申请号：US10865262
申请日：2004-06-10
申请人： Jean-Francois Lavallee , Terrence W. Doyle , Elise Rioux , Laurent Belec , Daniel Rabouin , Xavier Billot , Samuel Fortin
发明人： Jean-Francois Lavallee , Terrence W. Doyle , Elise Rioux , Laurent Belec , Daniel Rabouin , Xavier Billot , Samuel Fortin
IPC分类号： C07C43/162 , C07C43/164 , C07C43/166 , C07C49/225 , C07D237/36 , C07D239/70 , A61K31/085 , A61K31/121 , A61K31/502 , A61K31/517 , A61P35/00
CPC分类号： C07C45/292 , C07C49/755 , C07C69/757 , C07C323/59 , C07C2603/26 , C07F9/117
摘要： The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.
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公开(公告)号：US08329747B2
公开(公告)日：2012-12-11
申请号：US12535048
申请日：2009-08-04
申请人： Samuel Fortin
发明人： Samuel Fortin
IPC分类号： A61K31/22
CPC分类号： C07F9/65742 , C07C69/587 , C07C219/08 , C07C233/20 , C07D317/24 , C07D327/10 , C07F9/091
摘要： There are provided various polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds can be useful as cancer chemopreventive agents, cancer treating agent, inhibiting tumor growth or cell proliferation, reducing tumor growth or as radioenhencers for radiotherapy of cancer.
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公开(公告)号：US08198324B2
公开(公告)日：2012-06-12
申请号：US12536519
申请日：2009-08-06
申请人： Samuel Fortin
发明人： Samuel Fortin
CPC分类号： A61K31/232 , A61K9/127 , A61K31/047 , A61K31/12 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/23 , A61K36/02 , A61K36/282 , A61K36/30 , A61K36/48 , A61K36/52 , A61K36/55 , A61K36/9066 , A61K47/14 , Y02A50/463 , A61K2300/00
摘要： There are provided various compounds and compositions comprising polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds and compositions can be useful as cancer chemopreventive agents. They can also be useful for enhancing solubility of various active agents and enhancing their bioavailability.
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6.发明授权Method for treating an inflammatory disease with compositions comprising polyunsaturated fatty acid monoglycerides, derivatives thereof and uses thereof 有权用多不饱和脂肪酸单甘油酯，其衍生物和其用途的组合物治疗炎性疾病的方法公开(公告)号：US09101563B2
公开(公告)日：2015-08-11
申请号：US13459640
申请日：2012-04-30
申请人： Samuel Fortin
发明人： Samuel Fortin
IPC分类号： A61K31/20 , A61K31/047 , A61K31/12 , A61K31/122 , A61K36/02 , A61K36/282 , A61K36/30 , A61K36/48 , A61K36/52 , A61K36/55 , A61K36/9066 , A61K47/14 , A61K31/23 , A61K31/202 , A61K9/127
CPC分类号： A61K31/232 , A61K9/127 , A61K31/047 , A61K31/12 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/23 , A61K36/02 , A61K36/282 , A61K36/30 , A61K36/48 , A61K36/52 , A61K36/55 , A61K36/9066 , A61K47/14 , Y02A50/463 , A61K2300/00
摘要： There are provided various compounds and compositions comprising polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds and compositions can be useful as cancer chemopreventive agents. They can also be useful for enhancing solubility of various active agents and enhancing their bioavailability.
摘要翻译： 提供了包含多不饱和脂肪酸单甘油酯及其衍生物的各种化合物和组合物。 这些化合物和组合物可用作癌症化学预防剂。 它们也可用于增强各种活性剂的溶解度并提高其生物利用度。
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7.发明授权公开(公告)号：US08119690B2
公开(公告)日：2012-02-21
申请号：US12534439
申请日：2009-08-03
申请人： Samuel Fortin
发明人： Samuel Fortin
CPC分类号： C07F9/65742 , C07C69/587 , C07C219/08 , C07C233/20 , C07D317/24 , C07D327/10 , C07F9/091
摘要： There are provided various polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds can be useful as cancer chemopreventive agents, cancer treating agent, inhibiting tumor growth or cell proliferation, reducing tumor growth or as radioenhencers for radiotherapy of cancer.
摘要翻译： 提供了各种多不饱和脂肪酸单甘油酯及其衍生物。 这些化合物可用作癌症化学预防剂，癌症治疗剂，抑制肿瘤生长或细胞增殖，减少肿瘤生长或作为癌症放射治疗剂的放射线剂。
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8.发明授权Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof 有权包含多不饱和脂肪酸单甘油酯或其衍生物的组合物及其用途公开(公告)号：US08222295B2
公开(公告)日：2012-07-17
申请号：US12535990
申请日：2009-08-05
申请人： Samuel Fortin
发明人： Samuel Fortin
CPC分类号： A61K31/232 , A61K9/127 , A61K31/047 , A61K31/12 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/23 , A61K36/02 , A61K36/282 , A61K36/30 , A61K36/48 , A61K36/52 , A61K36/55 , A61K36/9066 , A61K47/14 , Y02A50/463 , A61K2300/00
摘要： There are provided various compounds and compositions comprising polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds and compositions can be useful as cancer chemopreventive agents. They can also be useful for enhancing solubility of various active agents and enhancing their bioavailability.
摘要翻译： 提供了包含多不饱和脂肪酸单甘油酯及其衍生物的各种化合物和组合物。 这些化合物和组合物可用作癌症化学预防剂。 它们也可用于增强各种活性剂的溶解度并提高其生物利用度。
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9.发明授权Compositions comprising polyunsaturated fatty acid monoglycerides, derivatives thereof and uses thereof 有权包含多不饱和脂肪酸单甘油酯的组合物，其衍生物及其用途公开(公告)号：US08722737B2
公开(公告)日：2014-05-13
申请号：US13459651
申请日：2012-04-30
申请人： Samuel Fortin
发明人： Samuel Fortin
IPC分类号： A61K31/22 , A61K31/20 , A61K31/045
CPC分类号： A61K31/232 , A61K9/127 , A61K31/047 , A61K31/12 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/23 , A61K36/02 , A61K36/282 , A61K36/30 , A61K36/48 , A61K36/52 , A61K36/55 , A61K36/9066 , A61K47/14 , Y02A50/463 , A61K2300/00
摘要： There are provided various compounds and compositions comprising polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds and compositions can be useful as cancer chemopreventive agents. They can also be useful for enhancing solubility of various active agents and enhancing their bioavailability.
摘要翻译： 提供了包含多不饱和脂肪酸单甘油酯及其衍生物的各种化合物和组合物。 这些化合物和组合物可用作癌症化学预防剂。 它们也可用于增强各种活性剂的溶解度并提高其生物利用度。
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