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公开(公告)号：US20230272098A1
公开(公告)日：2023-08-31
申请号：US18316811
申请日：2023-05-12
发明人： Laurens KRUIDENIER , Mahyar SABRIPOUR , Jeffry D. Watkins , Cindy T. DICKERSON , Rafael ROJAS , Matthew REISSMAN , Patricia MCNEELEY , Janine BILSBOROUGH , Dermot P. MCGOVERN , Dalin LI
IPC分类号： C07K16/28 , C12Q1/6883 , C12Q1/6851 , A61P1/04
CPC分类号： C07K16/2875 , C12Q1/6883 , C12Q1/6851 , A61P1/04 , C12Q2600/156 , C12Q2600/106 , C07K2317/52 , C07K2317/565 , C07K2317/24 , C07K2317/92 , C07K2317/76
摘要： Provided are methods, systems, and kits for selecting a subject for treatment with an inhibitor of Tumor necrosis factor-like cytokine 1A (TL1A) activity or expression based on a presence of one or more genotypes associated with a positive therapeutic response to the inhibitor of TL1A. Also provided are methods, systems and kits for detecting the one or more genotypes described herein.
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公开(公告)号：US20220259320A1
公开(公告)日：2022-08-18
申请号：US17682922
申请日：2022-02-28
发明人： Jeffry D. Watkins , Cindy T. Dickerson , Rafael Rojas , Matthew Reissman , Patricia McNeeley , Janine Bilsborough , Bradley Henkle , Stephan R. Targan
摘要： Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).
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公开(公告)号：US11999789B2
公开(公告)日：2024-06-04
申请号：US17682922
申请日：2022-02-28
发明人： Jeffry D. Watkins , Cindy T. Dickerson , Rafael Rojas , Matthew Reissman , Patricia McNeeley , Janine Bilsborough , Bradley Henkle , Stephan R. Targan
IPC分类号： C07K16/24 , A61P1/04 , C07K16/28 , A61K39/395 , C07K14/52 , C07K14/525
CPC分类号： C07K16/2875 , A61P1/04 , C07K16/241 , C07K2317/21 , C07K2317/24 , C07K2317/40 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/76
摘要： Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).
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公开(公告)号：US20230192835A1
公开(公告)日：2023-06-22
申请号：US17931049
申请日：2022-09-09
发明人： Jeffry D. Watkins , Cindy T. Dickerson , J. Monty Watkins , Patricia McNeeley , Janine Bilsborough , Bradley Henkle , Stephan R. Targan
CPC分类号： C07K16/24 , A61P1/04 , C07K16/241 , C07K16/28 , A61P1/00 , A61K9/0019 , C07K16/2875 , C12N15/09 , C12N15/63 , C12N5/10 , A61K39/3955
摘要： Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).
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公开(公告)号：US20240327532A1
公开(公告)日：2024-10-03
申请号：US18645261
申请日：2024-04-24
发明人： Jeffry D. Watkins , Cindy T. Dickerson , Rafael Rojas , Matthew Reissman , Patricia McNeeley , Janine Bilsborough , Bradley Henkle , Stephan R. Targan
CPC分类号： C07K16/2875 , A61P1/04 , C07K16/241 , C07K2317/21 , C07K2317/24 , C07K2317/40 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/76
摘要： Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).
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公开(公告)号：US11440954B2
公开(公告)日：2022-09-13
申请号：US16863971
申请日：2020-04-30
发明人： Jeffry D. Watkins , Cindy T. Dickerson , J. Monty Watkins , Patricia McNeeley , Janine Bilsborough , Bradley Henkle , Stephan R. Targan
IPC分类号： C07K16/24 , C07K16/28 , C12N5/10 , C12N15/09 , C12N15/63 , A61P1/04 , A61P1/00 , A61K9/00 , C07K14/525 , C07K14/715 , A61K39/395 , A61K39/00
摘要： Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).
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公开(公告)号：US11292848B2
公开(公告)日：2022-04-05
申请号：US17110004
申请日：2020-12-02
发明人： Jeffry D. Watkins , Cindy T. Dickerson , Rafael Rojas , Matthew Reissman , Patricia McNeeley , Janine Bilsborough , Bradley Henkle , Stephan R. Targan
IPC分类号： C07K16/24 , C07K16/28 , A61P1/04 , C07K14/52 , C07K14/525 , A61K39/395
摘要： Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).
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公开(公告)号：US20200255510A1
公开(公告)日：2020-08-13
申请号：US16863971
申请日：2020-04-30
摘要： Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).
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公开(公告)号：US20210122828A1
公开(公告)日：2021-04-29
申请号：US17110004
申请日：2020-12-02
摘要： Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).
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公开(公告)号：US10689439B2
公开(公告)日：2020-06-23
申请号：US16694814
申请日：2019-11-25
IPC分类号： C07K16/24 , C07K16/28 , A61K39/395 , A61P1/04 , C07K14/525 , C07K14/715 , A61K39/00
摘要： Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).
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