公开(公告)号：US20110202119A1

公开(公告)日：2011-08-18

申请号：US13121862

申请日：2009-09-30

申请人： Quan Ni ,  Mark Christopherson ,  Timothy Herbert ,  John Rondoni

发明人： Quan Ni ,  Mark Christopherson ,  Timothy Herbert ,  John Rondoni

IPC分类号： A61N1/00

CPC分类号： A61N1/3601 ,  A61B5/4818 ,  A61F2/848 ,  A61F2/86 ,  A61N1/37205

摘要： A system and method for treating sleep apnea includes inserting an implantable pulse generator subcutaneously within a body of a patient and connecting a lead to the pulse generator. The lead is inserted within the vasculature and advanced transvenously through the vasculature until a stimulation portion of the lead becomes positioned in close proximity to the hypoglossal nerve. A nerve-stimulation signal is applied to the hypoglossal nerve via the stimulation portion of the lead.

摘要翻译： 用于治疗睡眠呼吸暂停的系统和方法包括将植入式脉冲发生器皮下投入患者体内，并将引线连接到脉冲发生器。 铅被插入脉管系统中，并且通过脉管系统递送，直到引线的刺激部分定位在舌下神经附近。 神经刺激信号通过铅的刺激部分施加到舌下神经。

公开(公告)号：US20110152706A1

公开(公告)日：2011-06-23

申请号：US12992511

申请日：2009-05-15

申请人： Mark Christopherson ,  Timothy Herbert ,  Quan Ni

发明人： Mark Christopherson ,  Timothy Herbert ,  Quan Ni

IPC分类号： A61B5/08

CPC分类号： A61B5/03 ,  A61B5/01 ,  A61B5/4818 ,  A61N1/3601 ,  A61N1/36514 ,  A61N1/36521

摘要： A method and system for sensing respiration in the treatment of sleep apnea is disclosed.

摘要翻译： 公开了一种在睡眠呼吸暂停治疗中感测呼吸的方法和系统。

公开(公告)号：US20050209653A1

公开(公告)日：2005-09-22

申请号：US10801230

申请日：2004-03-16

申请人： Timothy Herbert ,  Warren Starkebaum

发明人： Timothy Herbert ,  Warren Starkebaum

IPC分类号： A61B5/0408 ,  A61N1/05 ,  A61N1/18 ,  A61N1/36 ,  A61N1/372 ,  A61N1/375

CPC分类号： A61N1/36007 ,  A61N1/0517 ,  A61N1/372 ,  A61N1/37205 ,  A61N1/3756 ,  Y02A90/26

摘要： An intra-luminal device for gastrointestinal electrical stimulation is self-powered and self-contained within a capsule-like housing, and is capable of non-surgical implantation within the patient. The device includes an implantable pulse generator and one or more electrodes mounted within a common device housing. The device housing is capable of endoscopic introduction to a desired location within the gastrointestinal tract, such as the stomach, via the esophagus. The device may be appropriate for short-term, mid-term or trial stimulation applications.

摘要翻译： 用于胃肠电刺激的腔内装置是自动供电的并且自包含在胶囊状壳体内，并且能够在患者体内非手术植入。 该装置包括可植入脉冲发生器和安装在公共装置外壳内的一个或多个电极。 装置外壳能够通过食道内窥镜引入胃肠道内的所需位置，例如胃。 该装置可适用于短期，中期或试验刺激应用。

公开(公告)号：US20070255336A1

公开(公告)日：2007-11-01

申请号：US11414515

申请日：2006-04-28

申请人： Timothy Herbert ,  Warren Starkebaum

发明人： Timothy Herbert ,  Warren Starkebaum

IPC分类号： A61N1/00

CPC分类号： A61N1/36007 ,  A61F5/0026 ,  A61F5/0059 ,  A61F2005/002 ,  A61N1/00 ,  A61N1/36082

摘要： This disclosure describes an implantable medical device that delivers electrical stimulation to a patient in combination with limiting ingestion of food by the patient to treat obesity. The device includes a gastric constriction device, such as a hydraulic or electro-mechanical gastric band, having a plurality of electrodes integrally formed thereon. One or more of the electrodes, i.e., an electrode combination, are selected to deliver electrical stimulation energy, e.g., in the form of stimulation pulses, to the patient. The electrode combination may deliver pulses in accordance with various modes, e.g., continuously, in a series of bursts, or a combination of both. When more than one electrode combination is selected, each electrode combination may deliver pulses in accordance with a different set of stimulation parameters. The electrode combinations may deliver pulses at the same time or on a time-interleaved basis.

摘要翻译： 本公开描述了一种可植入医疗装置，其将电刺激递送给患者，并结合限制患者摄取食物以治疗肥胖。 该装置包括胃收缩装置，例如液压或机电胃束带，其上形成有多个电极。 选择一个或多个电极，即电极组合，以将刺激能量（例如以刺激脉冲的形式）传递给患者。 电极组合可以根据各种模式（例如，连续地，一系列的脉冲串）或两者的组合来递送脉冲。 当选择多于一个电极组合时，每个电极组合可以根据不同的一组刺激参数递送脉冲。 电极组合可以在时间或时间交替的基础上递送脉冲。

公开(公告)号：US20070255335A1

公开(公告)日：2007-11-01

申请号：US11414502

申请日：2006-04-28

申请人： Timothy Herbert ,  Warren Starkebaum

发明人： Timothy Herbert ,  Warren Starkebaum

IPC分类号： A61N1/00

CPC分类号： A61N1/36007 ,  A61N1/05

摘要： This disclosure describes an implantable medical device that delivers electrical stimulation to a patient in combination with restriction ingestion of food by the patient to treaty obesity. The implantable medical device includes a gastric constriction device, such as a hydraulic or mechanical gastric band having a plurality of electrodes integrally formed thereon. A controller includes a control unit to control the degree of gastric constriction of the gastric constriction device and a pulse generator to control delivery of electrical stimulation to the patient. The control unit and pulse generator are enclosed within a housing implanted within the patient. By enclosing the control unit and pulse generator within a common housing, the trauma experienced by the patient during the implantation procedure may be substantially reduced. Additionally, the cost of the controller may be less than the cost of purchasing a control unit and a pulse generator separately.

摘要翻译： 本公开描述了一种可植入医疗装置，其将患者的电刺激与患者的食物的限制摄取结合到条约肥胖。 可植入医疗装置包括胃收缩装置，例如具有一体形成在其上的多个电极的液压或机械胃束带。 控制器包括控制单元，用于控制胃收缩装置的胃收缩程度和脉冲发生器，以控制对患者的电刺激递送。 控制单元和脉冲发生器被封装在植入患者体内的壳体内。 通过将控制单元和脉冲发生器包围在公共壳体内，患者在植入手术过程中经历的创伤可能会大大降低。 此外，控制器的成本可能小于单独购买控制单元和脉冲发生器的成本。

公开(公告)号：US20060265021A1

公开(公告)日：2006-11-23

申请号：US11379911

申请日：2006-04-24

申请人： Timothy Herbert ,  Warren Starkebaum

发明人： Timothy Herbert ,  Warren Starkebaum

IPC分类号： A61N1/36

CPC分类号： A61N1/36007 ,  A61N1/0517 ,  A61N1/372 ,  A61N1/37205 ,  A61N1/3756 ,  Y02A90/26

摘要： An intra-luminal device for gastrointestinal electrical stimulation is self-powered and self-contained within a capsule-like housing, and is capable of non-surgical implantation within the patient. The device includes an implantable pulse generator and one or more electrodes mounted within a common device housing. The device housing is capable of endoscopic introduction to a desired location within the gastrointestinal tract, such as the stomach, via the esophagus. The device may be appropriate for short-term, mid-term or trial stimulation applications.

摘要翻译： 用于胃肠电刺激的腔内装置是自动供电的并且自包含在胶囊状壳体内，并且能够在患者体内非手术植入。 该装置包括可植入脉冲发生器和安装在公共装置外壳内的一个或多个电极。 装置外壳能够通过食道内窥镜引入胃肠道内的所需位置，例如胃。 该装置可适用于短期，中期或试验刺激应用。

公开(公告)号：US5906210A

公开(公告)日：1999-05-25

申请号：US873700

申请日：1997-06-12

申请人： Timothy Herbert

发明人： Timothy Herbert

IPC分类号： A61B17/15 ,  A61B17/16 ,  A61B17/88 ,  A61F2/00 ,  A61F2/42 ,  A61F2/46 ,  A61B19/00 ,  A61B17/00

CPC分类号： A61B17/1686 ,  A61B17/15 ,  A61B17/1659 ,  A61B17/88 ,  A61F2/4261 ,  A61F2/4684 ,  A61F2002/4269 ,  A61F2310/00179

摘要： A method for restoration of stability and painfree rotation of the distal radio-ulna joint is based on raising the capsulo-retinacular flap by dissection off the dorsal part of the triangular fibro-cartilage complex distally and off the neck of the ulna proximally. After resection of the ulna head and reaming the distal end of the ulna to an appropriate depth and inserting the prosthesis into a suitable position the dorsal aspect of the triangular fibro-cartilage complex is reattached to the underside of the flap. Finally, the flap is reattached to the sigmoid notch of the radius and the wound is closed. By this way, painfree forearm rotation is restored and at the same time any length discrepancy is corrected.

摘要翻译： 用于恢复远端放射性尺骨关节的稳定性和无疼痛旋转的方法是基于通过从近端的三角形纤维 - 软骨复合体的背部和远端的尺骨的颈部解剖来提高囊 - 视网膜瓣。 在切除尺骨头后，将尺骨的远端延伸到适当的深度并将假体插入合适的位置，将三角形纤维软骨复合体的背侧重新连接到瓣的下侧。 最后，将瓣片重新连接到半径的乙状切口，伤口闭合。 通过这种方式，恢复无痛的前臂旋转，同时校正任何长度差异。