-
公开(公告)号：US20200219590A1
公开(公告)日：2020-07-09
申请号：US16686028
申请日：2019-11-15
Applicant: Quantum-Si Incorporated
Inventor： Brian Reed , Jeremy Lackey , Thomas Christian , Roger Nani , David Dodd , Kathren Croce , Alexander Goryaynov , Jonathan M. Rothberg
IPC: G16B50/30 , G16B25/10 , G16B40/00 , C12Q1/6806
Abstract: Aspects of the application provide methods of identifying and sequencing proteins, polypeptides, and amino acids, and compositions useful for the same. In some aspects, the application provides methods of obtaining data during a degradation process of a polypeptide, and outputting a sequence representative of the polypeptide. In some aspects, the application provides amino acid recognition molecules comprising a shielding element that enhances photostability in polypeptide sequencing reactions.
-
公开(公告)号：US20200209253A1
公开(公告)日：2020-07-02
申请号：US16708956
申请日：2019-12-10
Applicant: Quantum-Si Incorporated
Inventor： Brian Reed , Jeremy Lackey , Thomas Christian , Roger Nani , David Dodd , Kathren Croce , Alexander Goryaynov , Jonathan M. Rothberg
Abstract: Aspects of the application provide methods of identifying and sequencing proteins, polypeptides, and amino acids, and compositions useful for the same. In some aspects, the application provides methods of obtaining data during a degradation process of a polypeptide, and outputting a sequence representative of the polypeptide. In some aspects, the application provides amino acid recognition molecules comprising a shielding element that enhances photostability in polypeptide sequencing reactions.
-
公开(公告)号：US20210354133A1
公开(公告)日：2021-11-18
申请号：US17236804
申请日：2021-04-21
Applicant: Quantum-Si Incorporated
Inventor： Jonathan M. Rothberg , John H. Leamon , Jonathan C. Schultz , Michele Millham , Caixia Lv , Haidong Huang , Roger Nani , Omer Ad , Brian Reed , Matthew Dyer , Robert E. Boer
IPC: B01L3/00 , C12Q1/6806
Abstract: Methods and devices for preparing target molecules (e.g., target nucleic acids or target proteins) from a biological sample are provided herein. In some embodiments, methods and devices involve sample lysis, sample fragmentation, enrichment of target molecule(s), and/or functionalization of target molecule(s).
-
公开(公告)号：US20200209257A1
公开(公告)日：2020-07-02
申请号：US16709077
申请日：2019-12-10
Applicant: Quantum-Si Incorporated
Inventor： Brian Reed , Jeremy Lackey , Thomas Christian , Roger Nani , David Dodd , Kathren Croce , Alexander Goryaynov , Jonathan M. Rothberg
Abstract: Aspects of the application provide methods of identifying and sequencing proteins, polypeptides, and amino acids, and compositions useful for the same. In some aspects, the application provides methods of obtaining data during a degradation process of a polypeptide, and outputting a sequence representative of the polypeptide. In some aspects, the application provides amino acid recognition molecules comprising a shielding element that enhances photostability in polypeptide sequencing reactions.
-
公开(公告)号：US20200209256A1
公开(公告)日：2020-07-02
申请号：US16709052
申请日：2019-12-10
Applicant: Quantum-Si Incorporated
Inventor： Brian Reed , Jeremy Lackey , Thomas Christian , Roger Nani , David Dodd , Kathren Croce , Alexander Goryaynov , Jonathan M. Rothberg
Abstract: Aspects of the application provide methods of identifying and sequencing proteins, polypeptides, and amino acids, and compositions useful for the same. In some aspects, the application provides methods of obtaining data during a degradation process of a polypeptide, and outputting a sequence representative of the polypeptide. In some aspects, the application provides amino acid recognition molecules comprising a shielding element that enhances photostability in polypeptide sequencing reactions.
-
Patent Agency Ranking
公开(公告)号：US20230391799A1
公开(公告)日：2023-12-07
申请号：US18142378
申请日：2023-05-02
Applicant: Quantum-Si Incorporated
Inventor： Roger Nani , Haidong Huang
IPC: C07F5/02
CPC classification number: C07F5/022
Abstract: Aspects of the application provide compounds of formula (I):
or a salt thereof, which may be useful as chromophores and/or fluorophores for labeling highly water-soluble biomolecules (e.g., proteins, polypeptides, nucleotides, or oligonucleotides).-
公开(公告)号：US11358981B2
公开(公告)日：2022-06-14
申请号：US17153490
申请日：2021-01-20
Applicant: Quantum-Si Incorporated
Inventor： Haidong Huang , Roger Nani , Omer Ad , Robert E. Boer
IPC: C07K1/107 , C07K1/12 , C07K14/195
Abstract: The present disclosure relates to compounds and methods for selective C-terminal functionalization of peptides. In certain embodiments, the compounds have improved water-solubility, and are suitable for use in connection with peptide sequencing methodologies.
-
公开(公告)号：US20210354134A1
公开(公告)日：2021-11-18
申请号：US17236858
申请日：2021-04-21
Applicant: Quantum-Si Incorporated
Inventor： Jonathan M. Rothberg , John H. Leamon , Jonathan C. Schultz , Michele Millham , Caixia Lv , Haidong Huang , Roger Nani , Omer Ad , Brian Reed , Matthew Dyer , Robert E. Boer
IPC: B01L3/00 , C12Q1/6806
Abstract: Methods and devices for preparing target molecules (e.g., target nucleic acids or target proteins) from a biological sample are provided herein. In some embodiments, methods and devices involve sample lysis, sample fragmentation, enrichment of target molecule(s), and/or functionalization of target molecule(s).
-
公开(公告)号：US20200209254A1
公开(公告)日：2020-07-02
申请号：US16708989
申请日：2019-12-10
Applicant: Quantum-Si Incorporated
Inventor： Brian Reed , Jeremy Lackey , Thomas Christian , Roger Nani , David Dodd , Kathren Croce , Alexander Goryaynov , Jonathan M. Rothberg
IPC: G01N33/68
Abstract: Aspects of the application provide methods of identifying and sequencing proteins, polypeptides, and amino acids, and compositions useful for the same. In some aspects, the application provides methods of obtaining data during a degradation process of a polypeptide, and outputting a sequence representative of the polypeptide. In some aspects, the application provides amino acid recognition molecules comprising a shielding element that enhances photostability in polypeptide sequencing reactions.
-
公开(公告)号：US20200209249A1
公开(公告)日：2020-07-02
申请号：US16709103
申请日：2019-12-10
Applicant: Quantum-Si Incorporated
Inventor： Brian Reed , Jeremy Lackey , Thomas Christian , Roger Nani , David Dodd , Kathren Croce , Alexander Goryaynov , Jonathan M. Rothberg
Abstract: Aspects of the application provide methods of identifying and sequencing proteins, polypeptides, and amino acids, and compositions useful for the same. In some aspects, the application provides methods of obtaining data during a degradation process of a polypeptide, and outputting a sequence representative of the polypeptide. In some aspects, the application provides amino acid recognition molecules comprising a shielding element that enhances photostability in polypeptide sequencing reactions.
-
-
-
-
-
-
-
-
-
Search Results
16
records
(took 0.015 seconds)
