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公开(公告)号：US10857327B2
公开(公告)日：2020-12-08
申请号：US15235632
申请日：2016-08-12
IPC分类号： A61M25/00 , A61B90/11 , A61L31/02 , A61L31/06 , A61L31/10 , A61M5/142 , A61M25/02 , A61M25/06 , A61M25/09
摘要： A catheter assembly for insertion into the brain. The assembly comprises a first length of tubing made of a first material. A second material surrounds the first length of tubing, the second material being more flexible than the first material and having a hardness of less than 50 Rockwell E. The second material provides damping to the first length of tubing.
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公开(公告)号：US10086187B2
公开(公告)日：2018-10-02
申请号：US14374362
申请日：2013-02-07
摘要： Percutaneous access apparatus is described that includes a percutaneous fluid access device having an extracorporeal portion, one or more ports accessible from the extracorporeal portion and a septum for sealing each port. A connector device having one or more hollow needles is attachable to the percutaneous fluid access device. The apparatus also includes an attachment mechanism for attaching the connector device to the extracorporeal portion and an actuation mechanism that, after the connector device has been attached to the extracorporeal portion, can be used to drive the one or more hollow needles through the septum to establish fluid communication between the one or more hollow needles and the one or more ports. The apparatus may be used for neurosurgery applications.
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公开(公告)号：US20150040995A1
公开(公告)日：2015-02-12
申请号：US14374317
申请日：2013-02-07
IPC分类号： A61M39/10
CPC分类号： A61M39/1011 , A61M39/0247 , A61M2039/025 , A61M2039/1072 , A61M2210/0693 , Y10T137/1692
摘要： A medical fluid connector is described that includes a first fluid connector portion that can be connected to a second fluid connector portion. The first fluid connector portion includes a first locking member, a lumen and a septum for sealing the lumen. The second fluid connector portion includes a second locking member, a lumen and a hollow needle that is retained in and protrudes from the aperture at the end of the lumen. The variation in cross-sectional area of the fluid path through the fluid connector portion is less than 1 mm2 to reduce mixing effects. The use of such a connector for neurosurgical purposes is described.
摘要翻译： 描述了一种医疗流体连接器，其包括可连接到第二流体连接器部分的第一流体连接器部分。 第一流体连接器部分包括第一锁定构件，内腔和用于密封内腔的隔膜。 第二流体连接器部分包括第二锁定构件，内腔和中空针，其保持在腔的端部处并且从腔的端部突出。 通过流体连接器部分的流体路径的横截面积的变化小于1mm 2以减少混合效果。 描述了用于神经外科用途的这种连接器的使用。
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公开(公告)号：US10751520B2
公开(公告)日：2020-08-25
申请号：US14581549
申请日：2014-12-23
IPC分类号： A61M39/02
摘要： Apparatus for delivering therapeutic agents to the central nervous system of a subject is described. The apparatus includes at least one intracranial catheter and a percutaneous access device. The percutaneous access device includes a body having at least one extracorporeal surface and at least one subcutaneous surface, the body defining at least one port for connection to an implanted intracranial catheter. The port is accessible from the extracorporeal surface of the device, but is provided with a seal such as a rubber bung between the lumen of the port and the extracorporeal surface. The percutaneous access device may have more than two ports and/or a flange. A method of implanting the percutaneous access device is also described.
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公开(公告)号：US09132265B2
公开(公告)日：2015-09-15
申请号：US14262159
申请日：2014-04-25
CPC分类号： A61M39/0208 , A61M5/14 , A61M5/1408 , A61M5/142 , A61M5/14244 , A61M39/0247 , A61M39/10 , A61M2039/0205 , A61M2039/0229 , A61M2039/0232 , A61M2039/025 , A61M2039/1066 , A61M2205/04 , A61M2210/0693
摘要： A method for delivering fluid to a brain of a subject using a modular fluid delivery apparatus is described. The method comprises taking a subject having a first part of the modular fluid delivery apparatus subcutaneously implanted therein, the first part of the modular fluid delivery apparatus comprising a first end having a first fluid connector portion attached thereto and a second end being connected to one or more catheters implanted within the brain of the subject. The method also comprises taking a second part of the modular fluid delivery apparatus, the second part comprising a third end comprising a second fluid connector portion. The method further comprises making an incision in the subject to gain access to the first fluid connector portion of the first part of the modular fluid delivery apparatus, and connecting the first fluid connector portion to the second fluid connector portion.
摘要翻译： 描述了使用模块化流体输送装置将流体输送到对象的脑部的方法。 该方法包括将具有其中的模块化流体输送装置的第一部分的受试者皮下植入其中，模块化流体输送装置的第一部分包括具有连接到其上的第一流体连接器部分的第一端部， 更多的导管植入受试者的脑部。 该方法还包括取出模块化流体输送装置的第二部分，第二部分包括包括第二流体连接器部分的第三端。 该方法还包括在受试者中进行切口以进入模块化流体输送装置的第一部分的第一流体连接器部分，并将第一流体连接器部分连接到第二流体连接器部分。
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公开(公告)号：US20150018799A1
公开(公告)日：2015-01-15
申请号：US14374383
申请日：2013-02-07
CPC分类号： A61J1/20 , A61J1/1475 , A61J1/1481 , A61M5/002 , A61M5/142 , A61M25/0017 , A61M39/0247 , A61M39/04 , A61M39/08 , A61M39/10 , A61M39/1011 , A61M39/105 , A61M39/14 , A61M2039/0081 , A61M2039/009 , A61M2039/0205 , A61M2039/025 , A61M2039/0261 , A61M2039/0264 , A61M2039/027 , A61M2039/0276 , A61M2039/0282 , A61M2039/0288 , A61M2039/042 , A61M2039/1033 , A61M2039/1044 , A61M2210/0693
摘要： Fluid storage apparatus for medical use is described that includes a length of tubing having a first end and a second end. A first sealable connector portion is provided at the first end and a second sealable connector portion is provided at the second end. The volume of fluid that can be stored within the apparatus is known and an infusate or therapeutic agent is contained within the apparatus. In this manner, a known volume of therapeutic agent can be infused to a patient. The use in neurosurgical applications is described.
摘要翻译： 描述了用于医疗用途的流体存储装置，其包括具有第一端和第二端的一段管道。 第一可密封连接器部分设置在第一端，并且第二可密封连接器部分设置在第二端。 可以存储在装置内的流体的体积是已知的，并且灌注或治疗剂包含在装置内。 以这种方式，已知体积的治疗剂可以输注给患者。 描述神经外科应用中的用途。
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公开(公告)号：US10518075B2
公开(公告)日：2019-12-31
申请号：US14827720
申请日：2015-08-17
摘要： A method for delivering fluid to a brain of a subject is disclosed. This method includes the steps of: making one or more incisions in a subject; implanting one or more catheters in the brain of the subject; subcutaneously implanting a first part of a modular fluid delivery apparatus in the subject, the first part of the modular fluid delivery apparatus comprising a first length of tubing having a first end and a second end, the first end having a first fluid connector portion attached thereto and the second end being connected to the one or more catheters; and closing the one or more incisions such that the first part of the modular fluid delivery apparatus and the one or more catheters are entirely subcutaneously implanted within the subject.
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公开(公告)号：US20140371679A1
公开(公告)日：2014-12-18
申请号：US14374362
申请日：2013-02-07
CPC分类号： A61M39/0247 , A61B17/3403 , A61M39/04 , A61M39/10 , A61M39/1011 , A61M39/105 , A61M2039/0081 , A61M2039/009 , A61M2039/0205 , A61M2039/025 , A61M2039/0261 , A61M2039/0264 , A61M2039/027 , A61M2039/0276 , A61M2039/0282 , A61M2039/0288 , A61M2039/042 , A61M2039/1033 , A61M2039/1044 , A61M2210/0693
摘要： Percutaneous access apparatus is described that includes a percutaneous fluid access device having an extracorporeal portion, one or more ports accessible from the extracorporeal portion and a septum for sealing each port. A connector device having one or more hollow needles is attachable to the percutaneous fluid access device. The apparatus also includes an attachment mechanism for attaching the connector device to the extracorporeal portion and an actuation mechanism that, after the connector device has been attached to the extracorporeal portion, can be used to drive the one or more hollow needles through the septum to establish fluid communication between the one or more hollow needles and the one or more ports. The apparatus may be used for neurosurgery applications.
摘要翻译： 描述了包括具有体外部分的经皮流体通道装置，从体外部分可接近的一个或多个端口和用于密封每个端口的隔膜的经皮进入装置。 具有一个或多个中空针的连接器装置可附接到经皮流体接近装置。 该装置还包括用于将连接器装置附接到体外部分的附接机构和在连接器装置已经附接到体外部分之后的致动机构，其可以用于通过隔膜驱动一个或多个中空针，以建立 一个或多个中空针与一个或多个端口之间的流体连通。 该装置可用于神经外科应用。
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