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公开(公告)号：US09861475B2
公开(公告)日：2018-01-09
申请号：US12462956
申请日：2009-08-12
CPC分类号： A61F2/2418 , A61B2017/00243 , A61F2/2445 , A61F2/2454 , A61F2/2466 , A61F2220/0016
摘要： Devices, systems, and methods employ an implant that is sized and configured to attach to the annulus of a dysfunctional heart valve annulus. In use, the implant extends across the major axis of the annulus above and/or along the valve annulus. The implant reshapes the major axis dimension and/or other surrounding anatomic structures. The implant restores to the heart valve annulus and leaflets a more functional anatomic shape and tension. The more functional anatomic shape and tension are conducive to coaptation of the leaflets during systole, which, in turn, reduces regurgitation. The implant improves function to the valve, without surgically cinching, resecting, and/or fixing in position large portions of a dilated annulus, or without the surgical fixation of ring-like structures.
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2.发明授权公开(公告)号：US08142494B2
公开(公告)日：2012-03-27
申请号：US12386821
申请日：2009-04-23
IPC分类号： A61F2/24
CPC分类号： A61F2/2454
摘要： Devices, systems and methods retain a native heart valve leaflet to prevent retrograde flow. The devices, systems, and methods employ an implant that, in use, rests adjacent a valve annulus and includes a retaining structure that is sized and shaped to overlay at least a portion of one or more native valve leaflets. The retaining structure retains the leaflet or leaflets it overlays, to resist leaflet eversion and/or prolapse. In this way, the implant prevents or reduces regurgitation. The implant does not interfere significantly with the opening of and blood flow through the leaflets during periods of antegrade flow.
摘要翻译： 装置，系统和方法保留天然心脏瓣膜瓣以防止逆行流动。 装置，系统和方法采用植入物，其在使用中邻近瓣膜环并且包括保持结构，该保持结构的尺寸和形状可覆盖一个或多个天然瓣膜的至少一部分。 保留结构保留了覆盖的小叶或传单，以抵抗小叶外翻和/或脱垂。 以这种方式，植入物防止或减少反流。 植入物在顺行流动期间不会明显干扰通过传单的血液流通。
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公开(公告)号：US07691144B2
公开(公告)日：2010-04-06
申请号：US11089940
申请日：2005-03-25
IPC分类号： A61F2/24
CPC分类号： A61F2/2487 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61B2017/00876 , A61B2017/0417 , A61B2017/0453 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61F2/2445 , A61F2/2451 , A61F2/2454 , A61F2/2466 , A61F2210/009 , A61F2230/0093 , A61F2250/0012
摘要： Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.
摘要翻译： 植入物或植入物和方法的系统在左心房内或横过左心房施加选定的力向量或力向量的选择组合，这允许二尖瓣小叶更好地适应。 植入物和植入物和方法的植入物或系统使得可以快速部署，容易的血管内递送和完全的房内可检索性。 植入物或植入物和方法的植入物或系统也利用强荧光检查标志。 植入物和植入物和植入物的系统利用可调植入物和固定长度植入物。 植入物和植入物的方式的植入物或系统还可以利用桥接止动件来固定植入物，并且植入方法使用各种工具。
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公开(公告)号：US20090306622A1
公开(公告)日：2009-12-10
申请号：US12462956
申请日：2009-08-12
CPC分类号： A61F2/2418 , A61B2017/00243 , A61F2/2445 , A61F2/2454 , A61F2/2466 , A61F2220/0016
摘要： Devices, systems, and methods employ an implant that is sized and configured to attach to the annulus of a dysfunctional heart valve annulus. In use, the implant extends across the major axis of the annulus above and/or along the valve annulus. The implant reshapes the major axis dimension and/or other surrounding anatomic structures. The implant restores to the heart valve annulus and leaflets a more functional anatomic shape and tension. The more functional anatomic shape and tension are conducive to coaptation of the leaflets during systole, which, in turn, reduces regurgitation. The implant improves function to the valve, without surgically cinching, resecting, and/or fixing in position large portions of a dilated annulus, or without the surgical fixation of ring-like structures.
摘要翻译： 装置，系统和方法采用尺寸和构造成附着到功能障碍性心脏瓣膜环的环的植入物。 在使用中，植入物跨过瓣膜环上方和/或沿着瓣膜环的环的长轴延伸。 植入物重塑长轴尺寸和/或其他周围的解剖结构。 植入物恢复到心脏瓣膜环，并具有更多功能的解剖形状和张力。 更多功能的解剖形状和张力有利于收缩期间传单的接合，这反过来又降低了反流。 植入物可以改善瓣膜的功能，而无需外科手术收紧，切除和/或固定在扩张的环的大部分位置，或无环状结构的手术固定。
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5.发明申请公开(公告)号：US20120185040A1
公开(公告)日：2012-07-19
申请号：US13431430
申请日：2012-03-27
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2418 , A61F2/2454
摘要： Devices, systems and methods retain a native heart valve leaflet to prevent retrograde flow. The devices, systems, and methods employ an implant that, in use, rests adjacent a valve annulus and includes a retaining structure that is sized and shaped to overlay at least a portion of one or more native valve leaflets. The retaining structure retains the leaflet or leaflets it overlays, to resist leaflet eversion and/or prolapse. In this way, the implant prevents or reduces regurgitation. The implant does not interfere significantly with the opening of and blood flow through the leaflets during periods of antegrade flow.
摘要翻译： 装置，系统和方法保留天然心脏瓣膜瓣以防止逆行流动。 装置，系统和方法采用植入物，其在使用中邻近瓣膜环并且包括保持结构，该保持结构的尺寸和形状可覆盖一个或多个天然瓣膜的至少一部分。 保留结构保留了覆盖的小叶或传单，以抵抗小叶外翻和/或脱垂。 以这种方式，植入物防止或减少反流。 植入物在顺行流动期间不会明显干扰通过传单的血液流通。
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6.发明申请Devices, systems, and methods for reshaping a heart valve annulus, including the use of an adjustable bridge implant system 审中-公开用于重塑心脏瓣膜环的装置，系统和方法，包括使用可调节桥接植入系统公开(公告)号：US20090326648A1
公开(公告)日：2009-12-31
申请号：US12584272
申请日：2009-09-02
申请人： Timothy R. Machold , David J. Scott , David A. Rahdert , David Rainone Tholfsen , Robert T. Chang , John A. Macoviak
发明人： Timothy R. Machold , David J. Scott , David A. Rahdert , David Rainone Tholfsen , Robert T. Chang , John A. Macoviak
IPC分类号： A61F2/24
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0485 , A61B17/0487 , A61B17/3478 , A61B2017/00243 , A61B2017/00252 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61B2017/00876 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0451 , A61B2017/0453 , A61B2017/0454 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0496 , A61B2017/06176 , A61F2/2445 , A61F2/2451 , A61F2/2466 , A61F2/2487 , A61F2210/009 , A61F2250/0012
摘要： Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial adjustability and retrievability years after implant. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize an adjustable bridge stop to secure the implant, and the methods of implantation employ various tools.
摘要翻译： 植入物或植入物和方法的系统在左心房内或横过左心房施加选定的力向量或力向量的选择组合，这允许二尖瓣小叶更好地适应。 植入物和植入物和方法的植入物或系统使得植入后几年可以快速部署，容易的血管内递送和完全的心房内可调节性和可追溯性。 植入物或植入物和方法的植入物或系统也利用强荧光检查标志。 植入物和植入物和植入物的系统利用可调植入物和固定长度植入物。 植入物和植入物和方法的植入物或系统还可以利用可调节的桥接止挡来固定植入物，并且植入方法使用各种工具。
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7.发明授权Devices, systems, and methods for supplementing, repairing, or replacing a native heart valve leaflet 有权用于补充，修复或更换天然心脏瓣膜小叶的装置，系统和方法公开(公告)号：US07381220B2
公开(公告)日：2008-06-03
申请号：US10676815
申请日：2003-10-01
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2418 , A61F2/2454
摘要： Devices, systems and methods supplement, repair, or replace a native heart valve. The devices, systems, and methods employ an implant that, in use, extends adjacent a valve annulus. The implant includes a mobile neoleaflet element that occupies the space of at least a portion of one native valve leaflet. The implant mimics the one-way valve function of a native leaflet, to resist or prevent retrograde flow. The implant restores normal coaptation of the leaflets to resist retrograde flow, thereby resisting eversion and/or prolapse, which, in turn, reduces regurgitation.
摘要翻译： 装置，系统和方法补充，修理或更换原生心脏瓣膜。 装置，系统和方法采用在使用中邻近瓣膜环延伸的植入物。 植入物包括占据一个天然瓣膜小叶的至少一部分的空间的移动的新叶元件。 植入物模拟天然小叶的单向瓣膜功能，以抵抗或防止逆行流动。 植入物恢复小叶的正常接合以抵抗逆行流动，从而抵抗外翻和/或脱垂，这进而降低反流。
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公开(公告)号：US07291168B2
公开(公告)日：2007-11-06
申请号：US10695433
申请日：2003-10-28
IPC分类号： A61F2/06
CPC分类号： A61F2/2412 , A61B17/22012 , A61B18/1492 , A61B90/00 , A61B90/50 , A61B2017/00243 , A61B2017/00247 , A61B2017/22097 , A61B2017/320052 , A61B2018/00392 , A61F2/2445 , A61F2/2454 , A61F2/2466 , Y10S623/904
摘要： The present invention is a group of medical devices designed to improve heart valve function. The medical devices may be used individually, or in combination to supplement damaged valves, replace damaged valves, or improve damaged valves function. The medical devices include leaflet retainers, a neo-annulus, neo-leaflet, and a framework. In addition, the present invention is novel methods for surgically treating heart valves.
摘要翻译： 本发明是设计用于改善心脏瓣膜功能的一组医疗装置。 医疗设备可以单独使用，也可以组合使用以补充损坏的阀门，更换损坏的阀门，或改善损坏的阀门功能。 医疗装置包括小叶保持器，新环，新小叶和框架。 此外，本发明是用于手术治疗心脏瓣膜的新颖方法。
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9.发明授权公开(公告)号：US08956407B2
公开(公告)日：2015-02-17
申请号：US10894433
申请日：2004-07-19
CPC分类号： A61F2/2442 , A61B17/0469 , A61B2017/00876 , A61F2/2445 , A61F2/2451 , A61F2/2466 , A61F2/2487 , A61F2210/009 , A61F2250/0012 , A61F2250/0098 , Y10S623/904
摘要： Implants or systems of implants apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants also make use of strong fluoroscopic landmarks.
摘要翻译： 植入物或植入物系统在左心房内或穿过左心房施加选定的力矢量或力矢量的选择组合，这允许二尖瓣小叶更好地适应。 植入物或植入物系统使得可以快速部署，容易的血管内递送和完全的心房内可追溯性。 植入物或植入物系统还利用强荧光镜的地标。
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10.发明授权公开(公告)号：US08163013B2
公开(公告)日：2012-04-24
申请号：US12924219
申请日：2010-09-23
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61B2017/0417 , A61B2017/0453 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61F2/2445 , A61F2/2451 , A61F2/2487
摘要： Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.
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