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公开(公告)号：US20170340576A1
公开(公告)日：2017-11-30
申请号：US15621798
申请日：2017-06-13
Applicant: ROCA MEDICAL LTD.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
CPC classification number: A61K9/7046 , G06F19/326 , G06F19/328 , G06Q30/0635 , G06Q50/22 , G16H40/20 , G16H70/40
Abstract: A method for creating a multi-antigen patch, comprising providing one or more transdermal patch sheets having a plurality of single dose transdermal patches residing thereon, wherein each one of the plurality of single dose transdermal patches includes an antigen at a particular dilution level disposed within a carrier, removing one or more of the plurality of single dose transdermal patches from the one or more transdermal patch sheets, adhering the one or more of the plurality of single dose transdermal patches to a backing, wherein the backing allows for multiple single dose transdermal patches to be adjacently adhered thereon, and covering the plurality of transdermal patches adhered to the backing with a peelable release liner.
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公开(公告)号：US20170039346A1
公开(公告)日：2017-02-09
申请号：US15288352
申请日：2016-10-07
Applicant: ROCA MEDICAL LTD.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
CPC classification number: G06F19/3481 , A61K39/35 , A61K39/36 , A61K2039/54 , G16H20/10 , G16H40/20 , G16H70/40
Abstract: A method for delivering an immunomodulator to a patient includes providing a bottle of concentrated immunomodulator extract; progressively diluting the antigen extract in sterile bottles; selecting a prescribed amount from a desired one of the dilution bottles; providing a viscous encapsulation material that is able to introduce antigens contained therein through the skin of a patient; introducing one or more doses of the selected prescribed amount of diluted immunomodulator into the viscous encapsulation material; disposing a prescribed amount of viscous encapsulation material containing the introduced diluted immunomodulator therein within a container that is able to dispense such viscous encapsulation material containing the introduced diluted immunomodulator; dispensing from the container the amount of viscous encapsulation material containing the diluted immunomodulator in an amount equal to a single dose; and applying the dispensed viscous encapsulation material containing the introduced diluted immunomodulator to the skin by the patient or a medical professional.
Abstract translation: 向患者递送免疫调节剂的方法包括提供一瓶浓缩的免疫调节剂提取物; 逐渐稀释无菌瓶中的抗原提取物; 从期望的一个稀释瓶中选择规定量; 提供能够通过患者皮肤将包含在其中的抗原引入的粘性包封材料; 将一个或多个剂量的选择的规定量的稀释的免疫调节剂引入粘稠的包封材料中; 将含有引入的稀释免疫调节剂的规定量的粘稠包封材料置于容器内，该容器能够分配含有引入的稀释免疫调节剂的这种粘性包封材料; 从容器中分配含有等于单次剂量的稀释免疫调节剂的粘稠包封材料的量; 以及由患者或医疗专业人员将含有引入的稀释免疫调节剂的分散的粘稠包封材料施用于皮肤。
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公开(公告)号：US20170027494A1
公开(公告)日：2017-02-02
申请号：US15222709
申请日：2016-07-28
Applicant: ROCA MEDICAL LTD.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
Abstract: A prick test kit comprises a bottom tray containing a plurality of wells disposed in an array, wherein each of the wells contains a vial of a small amount of a specific well associated antigen, with each well and associated vial having a different antigen disposed therein, each of the vials having a rubber cap disposed thereon that is sterile and able to be pricked by a needle such that the small amount of antigen can be removed therefrom. A penetrating plate is disposed above the wells and having on the lower surface thereof diametrically opposite from the vials in the wells a plurality of piercing needles, one associated with each of the wells and directed downward there to but not touching any of the files. A separating plate is disposed between the bottom tray and the penetrating plate. A sterile covering is provided for containing the entire assembly.
Abstract translation: 刺针测试试剂盒包括底部托盘，其包含以阵列布置的多个孔，其中每个孔包含少量特定孔相关抗原的小瓶，每个孔和相关小瓶具有设置在其中的不同抗原， 每个小瓶具有布置在其上的橡胶帽，其是无菌的并且能够被针刺穿，使得可以从其中去除少量的抗原。 穿孔板设置在孔的上方，并且在其下表面上与孔中的小瓶在径向上相对地具有多个穿刺针，一个与每个孔相关联并且在其下方指向但不接触任何文件。 分离板设置在底部托盘和穿透板之间。 提供无菌覆盖物以容纳整个组件。
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公开(公告)号：US20160368626A1
公开(公告)日：2016-12-22
申请号：US15183719
申请日：2016-06-15
Applicant: ROCA MEDICAL LTD.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
Abstract: A method for delivering allergens to a pharmacist in a pre-diluted kit form, comprising providing a bulk container of base concentrate antigen containing at least one antigen at a predetermined concentrated level, creating a sequential and more diluted sequence of antigens, providing a plurality of end-use sealable containers that can receive a finite end amount of diluted antigens, dispensing from each of sequential bulk containers a finite end amount of diluted antigens into one of the plurality of end-use sealable containers, wherein the end-use seal containers filled from each of the sequential bulk containers comprises a group of end-use sealable containers associated with each of the sequential bulk containers, sealing each of the end-use containers after diluted antigens are disposed therein, and disposing a select number of the sealed end-use sealable containers from each of the groups of end-use sealable containers into a container comprising a kit.
Abstract translation: 一种以预先稀释的试剂盒形式向药剂师递送过敏原的方法，包括以预定的浓度水平提供含有至少一种抗原的碱性浓缩物抗原的散装容器，产生顺序和更加稀释的抗原序列，提供多种 最终使用的可密封的容器可以接收有限量的稀释的抗原，从每个顺序散装容器中分配有限量的稀释的抗原到多个最终使用的可密封容器之一，其中填充的最终用途密封容器 从每个顺序的散装容器中包括一组与每个顺序散装容器相关联的最终使用的可密封容器，在将稀释的抗原置于其中之后密封每个最终用途容器，并且设置一定数量的密封的末端 - 使用来自各组最终使用可密封容器的可密封容器进入包括试剂盒的容器中。
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公开(公告)号：US20160367437A1
公开(公告)日：2016-12-22
申请号：US15222790
申请日：2016-07-28
Applicant: ROCA MEDICAL LTD.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
CPC classification number: A61K39/35 , A61K2039/545
Abstract: A therapeutic treatment kit includes a container for holding a plurality of compartmentalized therapeutic dispensers. Each of the the therapeutic dispensers includes a plurality of vials of antigens, and a plurality of containers of supplements disposed in compartments, each of the compartments labeled with the name of the supplement. A compartment is also provided for containing applicators or the antigens, such that an individual can extract the antigen from the vial in a single dose; and para instructions associated with a therapeutic program for utilizing the vials of antigens and the supplements in accordance with a therapeutic program that is predefined. The construction of the kit, including the dosages of the antigen, the types of antigens and the supplements all associated with a particular therapeutic program.
Abstract translation: 治疗处理套件包括容纳多个分隔的治疗分配器的容器。 每个治疗分配器包括多个小瓶的抗原，以及多个放置在隔室中的补充容器，每个隔室用补充物的名称标记。 还提供用于容纳施用器或抗原的隔室，使得个体可以以单剂量从小瓶中提取抗原; 和与用于根据预定义的治疗程序利用抗原小瓶和补充剂的治疗程序相关联的对照说明。 试剂盒的构建，包括抗原的剂量，抗原类型和与特定治疗程序相关的补充剂。
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Patent Agency Ranking
公开(公告)号：US20220218819A1
公开(公告)日：2022-07-14
申请号：US17689710
申请日：2022-03-08
Applicant: ROCA Medical, Ltd.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
Abstract: A method for delivering allergens to a pharmacist in a pre-diluted kit form, comprising providing a bulk container of base concentrate antigen containing at least one antigen at a predetermined concentrated level, creating a sequential and more diluted sequence of antigens, providing a plurality of end-use sealable containers that can receive a finite end amount of diluted antigens, dispensing from each of sequential bulk containers a finite end amount of diluted antigens into one of the plurality of end-use sealable containers, wherein the end-use seal containers filled from each of the sequential bulk containers comprises a group of end-use sealable containers associated with each of the sequential bulk containers, sealing each of the end-use containers after diluted antigens are disposed therein, and disposing a select number of the sealed end-use sealable containers from each of the groups of end-use sealable containers into a container comprising a kit.
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公开(公告)号：US20170224267A1
公开(公告)日：2017-08-10
申请号：US15428045
申请日：2017-02-08
Applicant: ROCA MEDICAL LTD.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
Abstract: A method for producing prick test single use sterile vials for use in a prick test is provided. The method comprises providing at least one allergen source including therewithin allergen extract, providing a plurality of single dose vials, connecting a tube to the at least one allergen source, connecting a metering device to the tube, drawing by the tube an amount of the allergen extract from one of the at least one allergen source, receiving the amount of allergen extract at the metering device, and dispensing by the metering device a volume of allergen extract into one of the plurality of single dose vials.
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8.发明申请公开(公告)号：US20170024526A1
公开(公告)日：2017-01-26
申请号：US15171920
申请日：2016-06-02
Applicant: ROCA MEDICAL LTD.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
IPC: G06F19/00
CPC classification number: G06F19/328 , G06F19/326 , G06Q30/0635 , G06Q50/22
Abstract: The present disclosure provides a method for adjudicating reimbursement for allergens between a pharmacist and a reimbursing entity including obtaining at a central control center National Drug Codes (NDC's) for a plurality of allergens, determining by the central control center an Average Wholesale Price (AWP) for each of the allergens associated with each of the NDC's, accessing a third-party database accessible by a pharmacist and determining if any of the NDC's in the central control database are contained within the third-party database, and creating an adjudicating database at the central control center having defined benefits associated with reimbursable entities for each of the NDC's stored in the third-party database and in the central control database, wherein a pharmacist can access this information by accessing a particular NDC in the third-party database to obtain information and enter a claim.
Abstract translation: 本公开提供了一种用于裁定药剂师和报销实体之间的过敏原报销的方法，包括在中央控制中心获得多个过敏原的国家药物规范（NDC），由中央控制中心确定平均批发价格（AWP） 对于与每个NDC相关联的每个过敏原，访问由药剂师可访问的第三方数据库，并确定中央控制数据库中的任何NDC是否包含在第三方数据库内，以及在第三方数据库中创建一个裁决数据库 中央控制中心具有与存储在第三方数据库和中央控制数据库中的每个NDC的可偿还实体相关联的益处，其中药剂师可以通过访问第三方数据库中的特定NDC来访问该信息以获得信息 并输入索赔。
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9.发明申请METHOD FOR REPURPOSING NDC CODES IN A PHARMACEUTICAL DATABASE FOR VENOM DERIVED ALLERGENS INVOLVED IN VENOM IMMUNOTHERAPY 审中-公开用于在VENOM免疫组织中参与的VENOM衍生过敏体的药物数据库中的NDC代码的方法公开(公告)号：US20160371445A1
公开(公告)日：2016-12-22
申请号：US15235067
申请日：2016-08-11
Applicant: ROCA MEDICAL LTD.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
IPC: G06F19/00
CPC classification number: G06F19/328
Abstract: A method for adjudicating reimbursement for venom derived allergens between a pharmacist and a reimbursing entity comprises obtaining National Drug Codes (NDC's) for a plurality of venom derived allergens, storing in a central control database the obtained NDC's in association with an associated AWP and associated information for the venom derived allergen, which associated information includes translation information to allow practitioners to determine from a desired diluted level and number of doses of a desired NDC carrying venom derived antigen and a known dilution procedure how to translate back to the amount of base concentration of the NDC carrying venom derived antigen used to create the desired diluted level and number of doses, and determining if any of the NDC's in the central control database are contained within the third-party database and, if not, transferring the associated NDC's not in the third-party database to the third-party database.
Abstract translation: 一种用于裁定药剂师和报销实体之间的毒液衍生的过敏原报销的方法包括获得多种毒素衍生的变应原的国家药物代码（NDC），在中央控制数据库中存储获得的NDC与相关联的AWP和相关信息 对于毒液衍生的变应原，其相关信息包括翻译信息，以允许从业者从期望的稀释水平和携带毒液衍生的抗原的所需NDC的剂量数目和已知的稀释程序确定如何翻译为基础浓度 用于产生所需稀释水平和剂量数量的NDC携带毒液衍生的抗原，以及确定中央控制数据库中的任何NDC是否包含在第三方数据库内，如果不是，则将相关NDC不在 第三方数据库到第三方数据库。
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10.发明申请PREDICTIVE TRACKING SYSTEM FOR USE DATA IN THE ANTIGEN SUPPLY CHAIN TO DEFINE MANUFACTURING REQUIRED LEVELS 审中-公开用于在抗供体链中使用数据的预测跟踪系统，以确定制造所需水平公开(公告)号：US20160364738A1
公开(公告)日：2016-12-15
申请号：US15183715
申请日：2016-06-15
Applicant: ROCA MEDICAL LTD.
Inventor： JAMES STRADER , JOVAN HUTTON PULITZER
CPC classification number: G06Q30/0202 , G06N3/08
Abstract: A method for predicting demand for allergens for a given calendar time span utilizes a non-linear network having a set of inputs corresponding to inputs associated with economic and demand data with respect to use of allergens over a first defined time span of the calendar year from a first predetermined calendar day to a second predetermined calendar day. A predictive output is provided for yielding a prediction of economic and demand data over a second defined time span of the calendar year. The second defined time span of the calendar year is later than the first defined time span of the calendar year. The input actual data is through the trained representation to provide a prediction on the output thereof of the nonlinear network of the economic and demand data for the second defined time span of the calendar year.
Abstract translation: 用于预测给定日历时间跨度的过敏原需求的方法利用非线性网络，该非线性网络具有对应于经济和需求数据相关输入的一组输入，该输入相对于在日历年的第一规定的时间跨度使用过敏原 第一预定日历日到第二预定日历日。 提供了预测输出，用于在历年的第二个定义的时间跨度内产生经济和需求数据的预测。 日历年的第二个定义的时间间隔晚于日历年的第一个定义的时间跨度。 输入的实际数据是通过经过训练的表示，以便为日历年的第二定义时间跨度的经济和需求数据的非线性网络的输出提供预测。
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