公开(公告)号：US20230277595A1

公开(公告)日：2023-09-07

申请号：US18016978

申请日：2022-02-09

Applicant: ROHTO PHARMACEUTICAL CO., LTD. ,  OSAKA UNIVERSITY

Inventor： Shunbun KITA ,  Emi HORITANI ,  Norikazu MAEDA ,  Iichiro SHIMOMURA ,  Hiroyuki NISHIDA

IPC: A61K35/28 ,  A61P3/10

CPC classification number: A61K35/28 ,  A61P3/10

Abstract: The present invention aims to provide a prophylactic and/or therapeutic agent for diabetes that is highly effective on diabetes developed as a side effect from immune checkpoint inhibitors and has a certain effect on many patients. The present invention is a therapeutic agent for diabetes comprising mesenchymal stem cells. The prophylactic and/or therapeutic agents for diabetes of the present invention are suitably used particularly for diabetes caused by immune checkpoint inhibitors and diabetes caused by anti-PD-1 antibody or anti-PD-L1 antibody.

公开(公告)号：US20170035939A1

公开(公告)日：2017-02-09

申请号：US15291408

申请日：2016-10-12

Applicant: CELLSEED INC. ,  OSAKA UNIVERSITY

Inventor： Yukiko IMANISHI ,  Yoshiki SAWA ,  Iichiro SHIMOMURA ,  Norikazu MAEDA ,  Shigeru MIYAGAWA ,  Hideaki SAKAI

IPC: A61L27/38 ,  C12N5/077 ,  A61L27/36

CPC classification number: A61L27/3804 ,  A61K35/35 ,  A61L27/3683 ,  A61L27/3691 ,  A61L27/3695 ,  A61L27/3839 ,  A61L27/3891 ,  A61L2300/64 ,  A61L2430/20 ,  C12N5/0653 ,  C12N2500/38 ,  C12N2501/33 ,  C12N2501/39 ,  C12N2539/10

Abstract: The present invention aims to provide an artificial tissue that can efficiently reproduce myocardial tissue function and that can be used in an actual implantation and produced by culturing. The present invention relates to a graft material for treating myocardial disease, the graft material including a cell sheet containing adipocytes.

Abstract translation: 本发明的目的在于提供能够有效地再现心肌组织功能的人造组织，其可以用于实际植入中并通过培养产生。 本发明涉及用于治疗心肌疾病的移植材料，该移植材料包括含有脂肪细胞的细胞片。