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公开(公告)号：US3821268A
公开(公告)日：1974-06-28
申请号：US15236671
申请日：1971-06-11
Applicant: RORER INC WILLIAM H
IPC: A61K31/19 , A61K31/21 , A61K31/26 , A61K31/27 , C07C57/58 , C07C57/62 , C07C205/56 , C07C205/59 , C07C205/61 , C07C229/34 , C07C233/47 , C07C255/57 , C07C313/30 , C07C317/44 , C07C327/32 , C07C381/02 , C07D277/34 , C07D277/54 , C07C153/07
CPC classification number: C07C57/62 , A61K31/19 , A61K31/21 , A61K31/26 , A61K31/27 , C07C57/58 , C07C205/56 , C07C205/59 , C07C205/61 , C07C229/34 , C07C233/47 , C07C255/57 , C07C313/30 , C07C317/44 , C07C327/32 , C07C381/02 , C07C2601/14 , C07D277/34 , C07D277/54
Abstract: Novel Alpha -mercapto-p-biphenylylacetic acids and their derivatives have been prepared. Compounds of this invention possess useful anti-inflammatory, analgesic and antipyretic properties.
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公开(公告)号：US3767656A
公开(公告)日：1973-10-23
申请号：US3767656D
申请日：1971-10-14
Applicant: RORER INC WILLIAM H
IPC: C07D251/18 , C07D55/20
CPC classification number: C07D251/18 , Y10S514/926 , Y10S514/927
Abstract: NOVEL 4-ANILINO-2-AMINO-1,3,5-TRIAZINES, PROCESSES FOR PREPARING THE SAME AND THEIR METHOD OF TREATMENT OF HYPERTENSION AS MEDICINAL AGENTS ARE DESCRIBED. THE COMPOUNDS OF THIS INVENTION POSSESS UTILITY AS DIURETICS AND TREATMENT OF HYPERTENSION AND RELATED PATHOLOGICAL DISORDERS. THEY ARE ALSO USEFUL IN THE TREATING OF HYPERACIDITY AND ULCERATION.
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公开(公告)号：US3829467A
公开(公告)日：1974-08-13
申请号：US26874572
申请日：1972-07-03
Applicant: RORER INC WILLIAM H
IPC: C07C57/62 , C07C59/88 , C07C59/90 , C07C309/24 , C07C323/56 , C07C323/62 , C07C327/32 , C07C329/16 , C07C331/14 , C07C335/32 , C07C381/04 , C07C63/50
CPC classification number: C07C323/56 , C07C57/62 , C07C59/88 , C07C59/90 , C07C309/24 , C07C323/62 , C07C327/32 , C07C329/16 , C07C331/14 , C07C335/32 , C07C381/04 , C07C2602/28 , Y10S514/916
Abstract: NOVEL TETRAHYDRONAPHTHYLALKANOIC ACIDS AND THEIR DERIVATIVES SUCH AS ALPHA, 4-DICHLORO-5,6,7,8-TETRAHYDRO-2NAPTHYLACETIC ACID AND ITS DIETHYLAMMONIUM SALT, USEFUL FOR THE TREATMENT OF INFLAMMATION AND ASSOCIATED PAIN AND FEVER, ARE DESCRIBED.
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公开(公告)号：US3825553A
公开(公告)日：1974-07-23
申请号：US23370572
申请日：1972-03-10
Applicant: RORER INC WILLIAM H
IPC: A61K31/19 , A61K31/21 , A61K31/26 , A61K31/27 , C07C57/58 , C07C57/62 , C07C205/56 , C07C205/59 , C07C205/61 , C07C229/34 , C07C233/47 , C07C255/57 , C07C313/30 , C07C317/44 , C07C323/56 , C07C327/32 , C07C381/02 , C07D277/34 , C07D277/40 , C07D277/54 , C07D91/16
CPC classification number: C07C57/58 , A61K31/19 , A61K31/21 , A61K31/26 , A61K31/27 , C07C57/62 , C07C205/56 , C07C205/59 , C07C205/61 , C07C229/34 , C07C233/47 , C07C255/57 , C07C313/30 , C07C317/44 , C07C323/56 , C07C327/32 , C07C381/02 , C07C2601/14 , C07D277/34 , C07D277/54 , Y10S514/825
Abstract: CERTAIN SUBSTITUTED A-HAOL AND A-MERCAPTOPHENYLACETIC ACIDS AND SUBSTITUTED PHENYLACETIC ACIDS HAVING IN A-POSITION A SULFUR-CONTAINING GROUP, A CYANO GROUP, OR AN AMINO GROUP, THEIR SUBSTANTIALLY NON-TOXIC ESTERS, SALTS, AND ACID AMIDES AS WELL AS 5-PHENYL SUBSTITUTED 2-IMINO4-OXOTHIAZOLIDINES AND 5 - PHENYL SUBSTITUTED 2,4-DIOXOTHIAZOLIDINES HAVE A HIGH ANTI-INFLAMMATORY, ANALGESIC, AND ANTIPYRETIC ACTIVITY, LOW TOXICITY, AND/OR A FAVORABLE THERAPEUTIC INDEX WITH MINOR OR NO SIDE-EFFECTS. PREFERRED COMPOUNDS OF THIS INVENTION ARE A,M-DICHLORO-P-CYCLOHEXYLPHENYLACETIC ACIDS AND ITS ESTERS AND SALTS.
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5.发明授权Phosphonium compounds for treating gastrointestinal hyperacidity and ulceration 失效用于治疗胃肠功能不全和尿酸的磷化合物
公开(公告)号：US3810979A
公开(公告)日：1974-05-14
申请号：US32817673
申请日：1973-01-31
Applicant: RORER INC WILLIAM H
CPC classification number: C07F9/5456 , C07F9/50
Abstract: ARALKYL PHOSPHONIUM SALTS OF THIS INVENTION POSSESS USEFUL GASTIC ANTI-SECRETORY, SPASMOLYTIC AND ANTIULCEROGENIC PROPERTIES. A METHOD OF TREATING GASTROINTESTINAL HYPERACIDITY AND ULCERATION HAS ALSO BEEN DISCLOSED.
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Patent Agency Ranking
公开(公告)号：US3733416A
公开(公告)日：1973-05-15
申请号：US3733416D
申请日：1971-06-23
Applicant: RORER INC WILLIAM H
Inventor： DIAMOND J
IPC: A61K31/185 , C07C59/56 , A61K27/00
CPC classification number: A61K31/185 , C07C59/56
Abstract: A NOVEL METHOD OF REDUCING INFLAMMATION, PAIN AND FEVER IN MAMMALS BY THE ADMINISTERING OF P-CYCLOALKYLPHENYLGLYCOLIC ACID AND THEIR DERIVATIVES IS DISCLOSED.
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公开(公告)号：US3825597A
公开(公告)日：1974-07-23
申请号：US31814872
申请日：1972-12-26
Applicant: RORER INC WILLIAM H
Inventor： DIAMOND J
IPC: A61K31/155 , C07C335/32 , C07D295/215 , C07C123/00
CPC classification number: C07D295/215 , A61K31/155 , C07C335/32 , C07C2601/14 , Y10S514/927
Abstract: NOVEL THIOPSEUDOURONIUM COMPOUNDS HAVE BEEN PREPARED. COMPOUNDS OF THIS INVENTION POSSESS USEFUL GASTRIC ANTI-SECRETORY, SPASMOLYTIC AND ANTI-ULCEROGENIC PROPERTIES. A METHOD OF TREATING GASTROINTESTINAL HYPERACIDITY AND ULCERATION HAS ALSO BEEN DISCLOSED.
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公开(公告)号：US3825587A
公开(公告)日：1974-07-23
申请号：US23370472
申请日：1972-03-10
Applicant: RORER INC WILLIAM H
IPC: A61K31/19 , A61K31/21 , A61K31/26 , A61K31/27 , C07C57/58 , C07C57/62 , C07C205/56 , C07C205/61 , C07C229/34 , C07C233/47 , C07C255/57 , C07C313/30 , C07C317/44 , C07C323/56 , C07C327/32 , C07C381/02 , C07D277/34 , C07D277/54 , C07C63/00
CPC classification number: C07C255/57 , A61K31/19 , A61K31/21 , A61K31/26 , A61K31/27 , C07C57/58 , C07C57/62 , C07C205/56 , C07C205/61 , C07C229/34 , C07C233/47 , C07C313/30 , C07C317/44 , C07C323/56 , C07C327/32 , C07C381/02 , C07C2601/14 , C07D277/34 , C07D277/54
Abstract: ALPHA,ALPHA - DI - (M-CHLORO - P - CYCLOHEXYLPHENYL)ALPHA,ALPHA''-DITHIODIACETIC ACID AND ITS DIETHYLAMMONIUM SALT ARE DISCLOSED AND HAVE A HIGH ANTI-INFLAMMATORY, ANALGESIC, AND ANTIPYRETIC ACTIVITY, LOW TOXICITY, AND/OR A FAVORABLE THERAPEUTIC INDEX WITH MINOR OR NO SIDE-EFFECTS.
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公开(公告)号：US3758469A
公开(公告)日：1973-09-11
申请号：US3758469D
申请日：1971-10-14
Applicant: RORER INC WILLIAM H
Inventor： DIAMOND J
IPC: A61K31/53 , C07D251/18 , C07D55/20
CPC classification number: C07D251/18 , A61K31/53 , Y10S514/926 , Y10S514/927
Abstract: NOVEL 2-AMINO-4-AMILLINO-6-SUBSTITUTED 1,3,5-TRIAZINES, PROCESSES FOR PREPARING THE SAME AND THEIR METHOD OF TREATMENT OF HYPERTENSION AS MEDICINAL AGENT ARE DESCRIBED. THE COMPOUNDS OF THIS INVENTION ARE USEFUL IN THE TREATMENT OF GASTROINTESTINAL HYPERACIDITY AND ULCERATION. THESE COMPOUNDS ALSO HAVE UTILITY AS ANTIHYPERTENSIVE AGENTS.
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公开(公告)号：US3852323A
公开(公告)日：1974-12-03
申请号：US15238771
申请日：1971-06-11
Applicant: RORER INC WILLIAM H
IPC: A61K31/19 , A61K31/21 , A61K31/26 , A61K31/27 , C07C57/58 , C07C57/62 , C07C205/56 , C07C205/59 , C07C205/61 , C07C229/34 , C07C233/47 , C07C255/57 , C07C313/30 , C07C317/44 , C07C323/56 , C07C327/32 , C07C381/02 , C07D277/34 , C07D277/54 , C07C63/54 , C07C65/14 , C07C121/64
CPC classification number: C07C255/57 , A61K31/19 , A61K31/21 , A61K31/26 , A61K31/27 , C07C57/58 , C07C57/62 , C07C205/56 , C07C205/59 , C07C205/61 , C07C229/34 , C07C233/47 , C07C313/30 , C07C317/44 , C07C323/56 , C07C327/32 , C07C381/02 , C07C2601/14 , C07D277/34 , C07D277/54
Abstract: Novel Alpha -halo-p-cycloalkylphenylacetic acids and their derivatives have been prepared. Compounds of this invention possess useful anti-inflammatory, analgestic and antipyretic antipyretic properties.
Abstract translation: 已经制备了新的α-卤代 - 对环烷基苯基乙酸及其衍生物。 本发明的化合物具有有用的抗炎，止痛和解热解热特性。
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