Abstract:
Novel process for the preparation of steroids of the pregnane series from certain estrane derivatives which pregnanes are intermediates for cortisone derivatives.
Abstract:
WHEREIN R is alkyl of one to four carbon atoms and R'' is selected from the group consisting of hydrogen, acyl of an organic carboxylic acid of one to 18 carbon atoms and an organic ether radical, a novel process for preparing the corresponding Delta 4,9,11-gonatrienes and novel intermediates produced by the said processes.
A novel process for the preparation of 7 Alpha -methyl- Delta 4,9-gonadienes of the formula
Abstract:
Novel 7 Alpha -methyl- Delta 4,11-gonadiene of the formula
WHEREIN R is alkyl of one to four carbon atoms and R'' is selected from the group consisting of hydrogen, acyl of an organic carboxylic acid of one to 18 carbon atoms and an organic ether radical which have anabolic and androgenic activities and their preparation.
WHEREIN R IS ALKYL OF 1 TO 4 CARBON ATOMS, R1 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND SATURATED AND UNSATURATED HYDROCARBON WHICH MAY BE SUBSTITUTED AND X IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, ACYL OF AN ORGANIC CARBOXYLIC ACID OF 1 TO 18 CARBON ATOMS, ACYL OF A SUBSTITUTED CARBONIC ACID OF 1 TO 18 CARBON ATOMS AND ALIPHATIC, 5 TO 6 MEMBER CYCLIC AND HETEROCYCLIC HYDROCARBONS WHICH MAY BE SUBSTITUTED AND TO NOVEL PROCESSES FOR THEIR PREPARATION. THE INVENTION ALSO RELATES TO NOVEL ANABOLIC AND/OR ANDROGENIC COMPOSITIONS HAVING REDUCED OR NO ESTROGENIC ACTIVITY.
Abstract:
The preparation of 7 Alpha -methyl- Delta 4,9,11-estratrienes of the formula
WHEREIN R1 is selected from the group consisting of hydrogen and an acyl radical of an organic carboxylic acid of one to 18 carbon atoms and Y is selected from the group consisting of unsaturated aliphatic and halogenated unsaturated aliphatic radicals of two to four carbon atoms.
Abstract:
WHEREIN R IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, AN ACYL RADICAL OF AN ORGANIC CARBOXYLIC ACID OF 1 TO 18 CARBON ATOMS AND CERTAIN ALKYL COMPOUNDS AND TO NOVEL INTERMEDIATES PRODUCED THEREIN AND NOVEL PRODUCTS PRODUCED THEREBY WHICH HAVE ANABOLIC AND ANDROGENIC ACTIVITY. 2-(O=),17-(R-O-)-A-NOR-ESTRA-3(5),9,11-TRIENE
A PROCESS FOR THE PREPARATION OF A-NOR STEROIDS OF THE FORMULA