公开(公告)号：US5916264A

公开(公告)日：1999-06-29

申请号：US48358

申请日：1998-03-26

Applicant: Randolf Von Oepen ,  Nikolaus Reifart

Inventor： Randolf Von Oepen ,  Nikolaus Reifart

IPC: A61F2/00 ,  A61F2/07 ,  A61F2/852 ,  A61F2/89 ,  A61F2/90 ,  A61F2/91 ,  A61L27/00 ,  A61F2/06

CPC classification number: A61F2/07 ,  A61F2/852 ,  A61F2/89 ,  A61F2/90 ,  A61F2/91 ,  A61F2002/075 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2250/0007 ,  A61F2250/0063

Abstract: A stent graft has two coaxially arranged, radially expandable stents, and a flexible, stretchable material layer arranged between the stents. Both stents are directly connected with one another in their end regions and the material layer is formed as a fabric band wound around an inner stent.

Abstract translation: 支架移植物具有两个同轴布置的可径向扩张的支架和布置在支架之间的柔性的可拉伸材料层。 两个支架在其端部区域中彼此直接连接，并且材料层形成为缠绕在内支架上的织物带。

公开(公告)号：US08663311B2

公开(公告)日：2014-03-04

申请号：US11317495

申请日：2005-12-22

Applicant: Petrus Antonius Besselink ,  Travis Yribarren ,  Randolf Von Oepen

Inventor： Petrus Antonius Besselink ,  Travis Yribarren ,  Randolf Von Oepen

IPC: A61F2/06

CPC classification number: A61B17/11 ,  A61F2/0009 ,  A61F2/064 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/30062 ,  A61F2002/828 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0013 ,  B23K2103/42 ,  B23K2103/50 ,  B33Y80/00

Abstract: Expandable biodegradable devices formed of bistable and multistable unit cells for use in devices, such as stents and graft systems, are provided, in which the device has two or more stable configurations, including a contracted configuration and an expanded configuration, the contracted stable configuration having a smaller diameter than the expanded configuration.

Abstract translation: 提供了用于诸如支架和移植物系统的装置中的双稳态和多单元电池形成的可膨胀的可生物降解的装置，其中装置具有两个或多个稳定的构造，包括收缩构型和扩张构型，收缩的稳定构型具有 直径比扩张结构小。

公开(公告)号：US08530783B2

公开(公告)日：2013-09-10

申请号：US12699262

申请日：2010-02-03

Applicant: Rodney C. Ow ,  William E. Webler ,  Randolf Von Oepen

Inventor： Rodney C. Ow ,  William E. Webler ,  Randolf Von Oepen

IPC: B23K26/14

CPC classification number: B23K26/38

Abstract: A laser cutting system including a chamber configured to provide a controlled environment while the laser is being used to cut a pattern into a material to reduce or eliminate heat and oxygen related changes to the mechanical characteristics of the material. A system for providing a gas to the controlled environment within the chamber, as well as a means for exhausting gas and cutting debris from the chamber is also described. A cutting mandrel that provides for flow of a shielding gas and also provides a means for dispersing a laser beam before it can produce unwanted damage to a section of tubing is also described.

Abstract translation: 一种激光切割系统，包括被配置为在激光被用于将图案切割成材料以便减少或消除与材料的机械特性相关的热和氧相关变化时提供受控环境的腔室。 还描述了一种用于向室内的受控环境提供气体的系统，以及用于从气室排出气体和切割碎屑的装置。 还描述了提供保护气体流动的切割心轴，并且还提供了用于在激光束可以对管道的一部分产生不希望的损坏之前分散激光束的装置。

公开(公告)号：US20120239139A1

公开(公告)日：2012-09-20

申请号：US13481129

申请日：2012-05-25

Applicant: Stephan Wnendt ,  Randolf Von Oepen ,  Bernd Kuttler ,  Gerhard Lang ,  Guenter Lorenz ,  Axel Grandt

Inventor： Stephan Wnendt ,  Randolf Von Oepen ,  Bernd Kuttler ,  Gerhard Lang ,  Guenter Lorenz ,  Axel Grandt

IPC: A61F2/82 ,  B05D3/10

CPC classification number: A61L31/16 ,  A61L2300/416 ,  A61L2300/606

Abstract: Implants and methods of making same are provided for treatment or prophylaxis of coronary or peripheral vascular constrictions or vascular occlusions, and particularly, stenoses or restenoses, that comprise FK506 in chemically covalently bound, non-covalently bound or physically immobilized form.

Abstract translation: 提供了植入物及其制备方法，用于治疗或预防化学共价结合，非共价结合或物理固定化形式的冠状或外周血管收缩或血管闭塞，特别是狭窄或再狭窄，其包含FK506。

公开(公告)号：US20120209317A1

公开(公告)日：2012-08-16

申请号：US13028041

申请日：2011-02-15

Applicant: Randolf Von Oepen

Inventor： Randolf Von Oepen

IPC: A61B17/03

CPC classification number: A61B17/0057 ,  A61B17/0644 ,  A61B17/068 ,  A61B46/10 ,  A61B2017/00398 ,  A61B2017/00668

Abstract: A power driven vessel closure device is configured for closing a hole in a wall of a body lumen. The vessel closure device can include a power operated drive system and a closure element delivery system. The closure element delivery system can be removably, operably, couplable with the power operated drive system. That is, the closure element system can be directly or indirectly attached to and removed from the power operated drive system, or components thereof. The operation of the power operated drive system can operate the closure element delivery system so as to move the closure element within the vessel closure device and deploy the closure element to close the hole.

Abstract translation: 动力驱动的容器封闭装置构造成用于封闭体腔的壁中的孔。 容器封闭装置可以包括动力驱动的驱动系统和闭合元件输送系统。 闭合元件输送系统可以与动力驱动的驱动系统可拆卸地，可操作地连接。 也就是说，闭合元件系统可以直接或间接附接到动力驱动系统或其部件上并从其移除。 动力驱动驱动系统的操作可以操作闭合元件输送系统，以便将封闭元件移动到容器封闭装置内并展开封闭元件以封闭孔。

公开(公告)号：US08226603B2

公开(公告)日：2012-07-24

申请号：US12237998

申请日：2008-09-25

Applicant: Randolf Von Oepen ,  John Stankus ,  Barbara Stamberg ,  Travis R. Yribarren ,  Richard R. Newhauser

Inventor： Randolf Von Oepen ,  John Stankus ,  Barbara Stamberg ,  Travis R. Yribarren ,  Richard R. Newhauser

IPC: A61M31/00 ,  A61M37/00

CPC classification number: A61M25/10 ,  A61F2/958 ,  A61F2002/9583 ,  A61L29/085 ,  A61M25/1027 ,  A61M25/1029 ,  A61M25/1038 ,  A61M2025/1004 ,  A61M2025/1031 ,  A61M2025/105 ,  A61M2025/1075 ,  A61M2025/1086 ,  A61M2025/1088 ,  Y10T29/49826

Abstract: The present invention generally relates to an intraluminal catheter device for use in angioplasty and delivery of a therapeutic agent. Particularly, the present invention is directed to a catheter having an expandable member having a therapeutic agent disposed thereon and a fibrous matrix covering for delivering a therapeutic agent and methods of using the same.

Abstract translation: 本发明一般涉及用于血管成形术和治疗剂递送的管腔内导管装置。 特别地，本发明涉及具有设置在其上的治疗剂的可膨胀构件的导管和用于递送治疗剂的纤维基质覆盖物及其使用方法。

公开(公告)号：US20120123525A1

公开(公告)日：2012-05-17

申请号：US13298070

申请日：2011-11-16

Applicant: Pamela A. Kramer-Brown ,  Austin M. Leach ,  Randolf Von Oepen

Inventor： Pamela A. Kramer-Brown ,  Austin M. Leach ,  Randolf Von Oepen

IPC: A61F2/82

CPC classification number: A61L31/022 ,  A61L31/18

Abstract: Embodiments are directed to radiopaque implantable structures (e.g., stents) formed of cobalt-based alloys that comprise cobalt, chromium and one or more platinum group metals, refractory metals, or combinations thereof. Platinum group metals include platinum, palladium, ruthenium, rhodium, osmium, and iridium. Here, the term “refractory metals” include zirconium, niobium, rhodium, molybdenum, hafnium, tantalum, tungsten, rhenium, as well as the precious metals silver and gold. In one embodiment, the one or more included platinum group or refractory metals substitute for nickel, such that the alloy is substantially nickel free. The stents exhibit improved radiopacity as compared to similar alloys including greater amounts of nickel.

Abstract translation: 实施例涉及由包含钴，铬和一种或多种铂族金属，难熔金属或其组合的钴基合金形成的不透射线的可植入结构（例如，支架）。 铂族金属包括铂，钯，钌，铑，锇和铱。 这里，术语“难熔金属”包括锆，铌，铑，钼，铪，钽，钨，铼以及贵金属银和金。 在一个实施方案中，一种或多种包括的铂族或难熔金属代替镍，使得该合金基本上不含镍。 与包括更大量的镍的类似合金相比，支架表现出改善的射线不透性。

公开(公告)号：US08167929B2

公开(公告)日：2012-05-01

申请号：US11683995

申请日：2007-03-08

Applicant: Randolf Von Oepen ,  Thomas Michael Rieth ,  Lorcan James Coffey ,  Richard Roy Newhauser ,  Travis Richard Yribarren

Inventor： Randolf Von Oepen ,  Thomas Michael Rieth ,  Lorcan James Coffey ,  Richard Roy Newhauser ,  Travis Richard Yribarren

IPC: A61F2/06 ,  A61F2/82

CPC classification number: A61F2/954 ,  A61F2/91 ,  A61F2/958 ,  A61F2002/821 ,  A61F2250/0098 ,  A61M25/1002

Abstract: A stent delivery catheter system for accurately positioning a stent in a bifurcated vessel is disclosed. The system includes a catheter having a terminal portion and distal tip that is placed in a main branch of the vessel proximate the bifurcation. A fixed guidewire is attached to distal tip. A port is defined in the terminal portion of the catheter. The port is aligned with an ostium of a side branch of the bifurcated vessel to allow the passage of a stent delivery device, such as a balloon catheter having a stent crimped thereon, into the side branch. Radiopaque bands are positioned on opposite ends of the port. A positioning balloon is included on a surface of the catheter opposite the port and is selectively inflatable to position the radiopaque bands adjacent the side branch ostium. The radiopaque bands are referenced to place the stent proximate the side branch ostium.

Abstract translation: 公开了一种用于将支架精确定位在分叉血管中的支架输送导管系统。 该系统包括具有末端部分和远侧末端的导管，其被放置在靠近分叉处的血管的主分支中。 固定的导丝连接到远端。 端口被限定在导管的末端部分。 端口与分叉血管的侧分支的口对准，以允许支架输送装置（例如具有卷曲在其上的支架的球囊导管）通入侧支。 无线电波段位于端口的相对端。 定位球囊包括在导管的与端口相对的表面上，并且选择性地可充气以将不透射线的带定位在侧分支口附近。 参考不透射线带将支架置于侧分支口附近。

公开(公告)号：US20110208292A1

公开(公告)日：2011-08-25

申请号：US12708666

申请日：2010-02-19

Applicant: Randolf Von Oepen ,  Travis R. Yribarren

Inventor： Randolf Von Oepen ,  Travis R. Yribarren

IPC: A61F2/84

CPC classification number: A61F2/97 ,  A61F2002/9665

Abstract: A sheath assembly is provided for protecting a stent mounted on a catheter. An inner tubular member is positioned over the stent without longitudinal movement of the inner tubular member along the stent surface thereby eliminating the possibility of scraping or scratching a drug coating or polymer coating on the stent surface. An outer tubular member slides over the inner tubular member to firmly compress it onto the stent for further protection. In use, the outer tubular member is removed from over the inner tubular member so that the inner tubular member can open similar to a clamshell opening radially outwardly away from the stent without longitudinal movement along the stent surface.

Abstract translation: 提供护套组件用于保护安装在导管上的支架。 内部管状构件被定位在支架上方，而不沿着支架表面的内部管状构件的纵向运动，从而消除刮擦或刮擦支架表面上的药物涂层或聚合物涂层的可能性。 外部管状构件在内部管状构件上滑动以将其牢固地压缩到支架上用于进一步保护。 在使用中，外部管状构件从内部管状构件上方移除，使得内部管状构件可以类似于离开支架径向向外的蛤壳式开口而不沿着支架表面纵向移动而打开。

公开(公告)号：US07993303B2

公开(公告)日：2011-08-09

申请号：US11738384

申请日：2007-04-20

Applicant: Randolf Von Oepen ,  Ian J. Clark ,  Lorcan Coffey ,  Thomas Rieth ,  Richard Newhauser ,  Travis Yribarren ,  Marc Gianotti ,  Bernhard Uihlein

Inventor： Randolf Von Oepen ,  Ian J. Clark ,  Lorcan Coffey ,  Thomas Rieth ,  Richard Newhauser ,  Travis Yribarren ,  Marc Gianotti ,  Bernhard Uihlein

IPC: A61M29/00

CPC classification number: A61M25/0054 ,  A61M25/0053 ,  A61M2025/0006 ,  A61M2025/0025 ,  A61M2025/0063

Abstract: A support catheter that can puncture a heart septum with a guidewire without buckling and that can access difficult to reach arteries such as carotid or renal arteries from the aorta under difficult circumstances is provided. The support catheter comprises a catheter body having a proximal end, a distal end, and an interior wall surface defining a first lumen extending from the proximal end toward the distal end. A second lumen is disposed between the interior wall surface and an outer surface of the catheter body. A plurality of stiffening members is disposed around the second lumen, the plurality of stiffening members being engageable to selectively stiffen the catheter body. In another configuration, the catheter further comprises a second plurality of stiffening members disposed between the first lumen and the second lumen.

Abstract translation: 提供了一种支撑导管，其可以用导线刺穿心脏隔膜而没有屈曲，并且可以在困难的情况下进入难以到达主动脉的颈动脉或肾动脉的动脉。 支撑导管包括具有近端，远端和限定从近端朝向远端延伸的第一内腔的内壁表面的导管主体。 第二管腔设置在内壁表面和导管主体的外表面之间。 多个加强构件设置在第二内腔周围，多个加强构件可接合以选择性地加强导管主体。 在另一种构造中，导管还包括设置在第一腔和第二腔之间的第二多个加强构件。