公开(公告)号：US20070167971A1

公开(公告)日：2007-07-19

申请号：US11654409

申请日：2007-01-17

申请人： Raymond Huey ,  Jeffrey Horn ,  Denny Lo

发明人： Raymond Huey ,  Jeffrey Horn ,  Denny Lo

IPC分类号： A61M29/00

CPC分类号： A61M25/10 ,  A61M25/0074 ,  A61M25/0082 ,  A61M25/1011 ,  A61M25/1027 ,  A61M2025/0057 ,  A61M2025/105 ,  A61M2025/1088

摘要： A device for promoting the clotting of blood in body cavities includes a flexible body portion; an expandable member located on the flexible body portion; and a blood clotting material attached to the expandable member. When used, insertion of at least a portion of the blood clotting material into the body cavity causes at least a portion of the blood clotting material to contact blood emanating from a bleed site. Methods of providing therapies to tube-shaped organs include the steps of providing suitable devices having expansion capabilities, positioning the devices at the appropriate bleed sites, and expanding the devices to cause blood clotting materials to contact the bleed sites. Materials that may be used as the blood clotting material include zeolites, molecular sieve materials, diatomaceous earth, clay, silica-based materials, oxidized cellulose, carboxymethyl cellulose, bioactive glass, biological hemostats, chitosan, and combinations of the foregoing.

摘要翻译： 用于促进体腔内的血液凝结的装置包括柔性体部分; 位于所述柔性主体部分上的可扩张构件; 以及附着在可扩张构件上的血液凝固材料。 当使用时，将至少一部分血液凝固材料插入体腔使至少一部分血液凝固材料接触从出血部位发出的血液。 向管状器官提供疗法的方法包括提供具有扩张能力的合适装置，将装置定位在适当的血液部位，以及扩张装置以使血液凝固材料接触出血部位的步骤。 可用作血液凝固材料的材料包括沸石，分子筛材料，硅藻土，粘土，二氧化硅基材料，氧化纤维素，羧甲基纤维素，生物活性玻璃，生物止血剂，壳聚糖以及上述组合。

公开(公告)号：US20070134293A1

公开(公告)日：2007-06-14

申请号：US11634673

申请日：2006-12-05

申请人： Raymond Huey ,  Jeffrey Horn ,  Denny Lo

发明人： Raymond Huey ,  Jeffrey Horn ,  Denny Lo

IPC分类号： A61F2/00

CPC分类号： A61L15/18 ,  A61L15/42

摘要： An apparatus for promoting the clotting of blood comprises a receptacle, at least a portion of which is defined by a mesh having openings therein, and particles of clay retained in the receptacle. In similar apparatuses, bioactive glass or chitosan is retained in the receptacle. An apparatus also comprises a receptacle defined by a mesh having openings therein, and first and second blood clotting materials enclosed in the mesh. In a method of dressing a bleeding wound, a first blood clotting material in particle form is provided and retained in a mesh structure, and a second blood clotting material is provided and incorporated into a material of the mesh structure. The mesh structure is placed on a bleeding wound such that the second blood clotting material contacts wounded tissue of the bleeding wound.

摘要翻译： 用于促进血液凝结的装置包括容器，其容器的至少一部分由其中具有开口的网和保留在容器中的粘土颗粒限定。 在类似的装置中，生物活性玻璃或壳聚糖保留在容器中。 装置还包括由其中具有开口的网状物限定的容器，以及封闭在网中的第一和第二血液凝固材料。 在敷料出血伤口的方法中，提供颗粒形式的第一血液凝固材料并保留在网状结构中，并且提供第二种凝血材料并将其并入网状结构的材料中。 将网状结构放置在流血的伤口上，使得第二血液凝固材料接触出血伤口的伤口组织。

公开(公告)号：US07604819B2

公开(公告)日：2009-10-20

申请号：US11715057

申请日：2007-03-06

申请人： Raymond Huey ,  Denny Lo ,  Daniel J. Burns

发明人： Raymond Huey ,  Denny Lo ,  Daniel J. Burns

IPC分类号： A61L15/14 ,  A61K9/14 ,  A61F13/00 ,  A61F13/37 ,  A61L15/16 ,  A61L15/18

CPC分类号： A61L15/44 ,  A61F13/00012 ,  A61F13/00063 ,  A61L15/18 ,  A61L15/28 ,  A61L15/425 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2400/04 ,  A61L2400/16

摘要： A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

摘要翻译： 用于促进血液凝结的止血装置包括纱布基底，布置在纱布基底上的粘土材料，以及布置在纱布基底上以粘合粘土材料的多元醇，例如甘油等。 当该装置用于治疗流血的伤口时，至少一部分粘土材料与从伤口发出的血液接触以引起凝血。 可以应用于流血伤口以促进血液凝结的绷带包括安装在其上的柔性基底和纱布基底。 纱布基材包括粘土材料和多元醇。 止血海绵还包括纱布基底和止血材料和多元醇在基底的第一表面上的分散体。

公开(公告)号：US20090186071A1

公开(公告)日：2009-07-23

申请号：US12417802

申请日：2009-04-03

申请人： Raymond Huey ,  Denny Lo ,  Daniel J. Burns

发明人： Raymond Huey ,  Denny Lo ,  Daniel J. Burns

IPC分类号： A61K9/70 ,  A61K33/34 ,  A61K33/38 ,  A61P17/02

CPC分类号： A61F13/534 ,  A61L15/18 ,  A61L15/44 ,  A61L2300/102 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/41 ,  A61L2300/418 ,  A61L2400/04

摘要： A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

摘要翻译： 用于促进血液凝结的装置包括颗粒形式的粘土材料和用于容纳粘土材料的容器。 容器的至少一部分由网格限定。 另一种装置包括纱布基底和布置在纱布基底上的粘土材料。 另一种装置是包括基底，安装在基底上的网和保留在网中的粘土材料颗粒的绷带。 止血海绵包括基材，设置在基材的第一表面上的止血材料和设置在基材的第二表面上的脱模剂。 脱模剂设置在基材的卷绕接触表面上。 当治疗出血的伤口时，止血海绵的施用使至少一部分止血材料通过脱模剂和通过基底与血液接触。

公开(公告)号：US20080097271A1

公开(公告)日：2008-04-24

申请号：US11584079

申请日：2006-10-20

申请人： Denny Lo ,  Raymond Huey

发明人： Denny Lo ,  Raymond Huey

IPC分类号： A61F13/40

CPC分类号： A61F13/00034 ,  A61F2013/00463 ,  A61F2013/00472 ,  A61F2013/00548 ,  A61F2013/00561 ,  A61F2013/00902 ,  A61F2013/0091 ,  A61L15/18 ,  A61L2400/04

摘要： A hemostatic agent applicable to a bleeding wound to promote the clotting of blood comprises a first component and a second component, both components being in particle form and commingled with each other, and both components having hemostatic properties. A device incorporating such an agent comprises a receptacle for retaining the agent in particulate form therein. At least a portion of the receptacle is defined by a mesh having openings therein through which the blood may flow to come into contact with the particles of the hemostatic agent. A pad for controlling the flow of blood from a bleeding wound comprises a mesh structure and the hemostatic agent retained therein. A bandage applicable to a bleeding wound is defined by a substrate, a mesh mounted on the substrate, and the hemostatic agent retained in the mesh.

摘要翻译： 适用于出血伤口以促进血液凝结的止血剂包括第一组分和第二组分，两种组分均为颗粒形式并且彼此混合，并且两种组分均具有止血性质。 包含这种试剂的装置包括用于将试剂保持在其中的颗粒形式的容器。 容器的至少一部分由其中具有开口的网眼限定，血液可以通过该网孔流动以与止血剂的颗粒接触。 用于控制来自出血性伤口的血液流动的垫包括网状结构，并且止血剂保留在其中。 适用于出血性伤口的绷带由基材，安装在基底上的网和保留在网中的止血剂限定。

公开(公告)号：US20070276345A1

公开(公告)日：2007-11-29

申请号：US11715057

申请日：2007-03-06

申请人： Raymond Huey ,  Denny Lo ,  Daniel J. Burns

发明人： Raymond Huey ,  Denny Lo ,  Daniel J. Burns

IPC分类号： A61M35/00

CPC分类号： A61L15/44 ,  A61F13/00012 ,  A61F13/00063 ,  A61L15/18 ,  A61L15/28 ,  A61L15/425 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2400/04 ,  A61L2400/16

摘要： A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

摘要翻译： 用于促进血液凝结的止血装置包括纱布基底，布置在纱布基底上的粘土材料，以及设置在纱布基底上以粘合粘土材料的多元醇，例如甘油等。 当该装置用于治疗流血的伤口时，至少一部分粘土材料与从伤口发出的血液接触以引起凝血。 可以应用于流血伤口以促进血液凝结的绷带包括安装在其上的柔性基底和纱布基底。 纱布基材包括粘土材料和多元醇。 止血海绵还包括纱布基底和止血材料和多元醇在基底的第一表面上的分散体。

公开(公告)号：US20070275073A1

公开(公告)日：2007-11-29

申请号：US11590427

申请日：2006-10-30

申请人： Raymond Huey ,  Denny Lo ,  Daniel J. Burns

发明人： Raymond Huey ,  Denny Lo ,  Daniel J. Burns

IPC分类号： A61K9/14

CPC分类号： A61F13/534 ,  A61L15/18 ,  A61L15/44 ,  A61L2300/102 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/41 ,  A61L2300/418 ,  A61L2400/04

摘要： A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

摘要翻译： 用于促进血液凝结的装置包括颗粒形式的粘土材料和用于容纳粘土材料的容器。 容器的至少一部分由网格限定。 另一种装置包括纱布基底和布置在纱布基底上的粘土材料。 另一种装置是包括基底，安装在基底上的网和保留在网中的粘土材料颗粒的绷带。 止血海绵包括基材，设置在基材的第一表面上的止血材料和设置在基材的第二表面上的脱模剂。 脱模剂设置在基材的卷绕接触表面上。 当治疗出血的伤口时，止血海绵的施用使至少一部分止血材料通过脱模剂和通过基底与血液接触。

公开(公告)号：US08343537B2

公开(公告)日：2013-01-01

申请号：US13363270

申请日：2012-01-31

申请人： Raymond J. Huey ,  Denny Lo ,  Daniel J. Burns ,  Giacomo Basadonna ,  Francis X. Hursey

发明人： Raymond J. Huey ,  Denny Lo ,  Daniel J. Burns ,  Giacomo Basadonna ,  Francis X. Hursey

IPC分类号： A61L15/14 ,  A61L15/16 ,  A61L15/18 ,  A61K9/14 ,  A61F13/00

CPC分类号： A61L15/44 ,  A61F13/00012 ,  A61F13/00063 ,  A61L15/18 ,  A61L15/28 ,  A61L15/425 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2400/04 ,  A61L2400/16

摘要： A hemostatic device for promoting the dotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

摘要翻译： 用于促进血液点滴的止血装置包括纱布基材，布置在纱布基材上的粘土材料，以及布置在纱布基材上以粘合粘土材料的多元醇如甘油等。 当该装置用于治疗流血的伤口时，至少一部分粘土材料与从伤口发出的血液接触以引起凝血。 可以应用于流血伤口以促进血液凝结的绷带包括安装在其上的柔性基底和纱布基底。 纱布基材包括粘土材料和多元醇。 止血海绵还包括纱布基底和止血材料和多元醇在基底的第一表面上的分散体。

公开(公告)号：US20110268784A1

公开(公告)日：2011-11-03

申请号：US13115699

申请日：2011-05-25

申请人： Raymond J. Huey ,  Denny Lo ,  Daniel J. Burns ,  Giacomo Basadonna ,  Francis X. Hursey

发明人： Raymond J. Huey ,  Denny Lo ,  Daniel J. Burns ,  Giacomo Basadonna ,  Francis X. Hursey

IPC分类号： A61K9/70 ,  A61K33/38 ,  A61P31/10 ,  A61P7/04 ,  A61P29/00 ,  A61P31/00 ,  A61K33/06 ,  A61K33/34

CPC分类号： A61F13/534 ,  A61L15/18 ,  A61L15/44 ,  A61L2300/102 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/41 ,  A61L2300/418 ,  A61L2400/04

摘要： A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

摘要翻译： 用于促进血液凝结的装置包括颗粒形式的粘土材料和用于容纳粘土材料的容器。 容器的至少一部分由网格限定。 另一种装置包括纱布基底和布置在纱布基底上的粘土材料。 另一种装置是包括基底，安装在基底上的网和保留在网中的粘土材料颗粒的绷带。 止血海绵包括基材，设置在基材的第一表面上的止血材料和设置在基材的第二表面上的脱模剂。 脱模剂设置在基材的卷绕接触表面上。 当治疗出血的伤口时，止血海绵的施用使至少一部分止血材料通过脱模剂和通过基底与血液接触。

公开(公告)号：US07968114B2

公开(公告)日：2011-06-28

申请号：US11590427

申请日：2006-10-30

申请人： Raymond J. Huey ,  Denny Lo ,  Daniel J. Burns ,  Giacomo Basadonna ,  Francis X. Hursey

发明人： Raymond J. Huey ,  Denny Lo ,  Daniel J. Burns ,  Giacomo Basadonna ,  Francis X. Hursey

IPC分类号： A61L15/14 ,  A61L15/16 ,  A61L15/18 ,  A61K9/14 ,  A61F13/00 ,  A61F13/37

CPC分类号： A61F13/534 ,  A61L15/18 ,  A61L15/44 ,  A61L2300/102 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/41 ,  A61L2300/418 ,  A61L2400/04

摘要： A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

摘要翻译： 用于促进血液凝结的装置包括颗粒形式的粘土材料和用于容纳粘土材料的容器。 容器的至少一部分由网格限定。 另一种装置包括纱布基底和布置在纱布基底上的粘土材料。 另一种装置是包括基底，安装在基底上的网和保留在网中的粘土材料颗粒的绷带。 止血海绵包括基材，设置在基材的第一表面上的止血材料和设置在基材的第二表面上的脱模剂。 脱模剂设置在基材的卷绕接触表面上。 当治疗出血的伤口时，止血海绵的施用使至少一部分止血材料通过脱模剂和通过基底与血液接触。