公开(公告)号：US20210113621A1

公开(公告)日：2021-04-22

申请号：US17132634

申请日：2020-12-23

Applicant: Regenexx, LLC

Inventor： Christopher J. Centeno ,  Neven Steinmetz ,  Ian Stemper ,  Dustin Berger

IPC: A61K35/19 ,  C12N5/078 ,  C12M1/00 ,  A61K45/06 ,  C12N5/00

Abstract: Apparatus, kit and method embodiments are disclosed herein that provide for the production of a modified autologous platelet mixture at a patient bedside for contemporaneous reinjection to the patient using a platelet lysis apparatus. Representative platelet lysis apparatus may include a housing supporting a sample tube and a thermal mass element connected to or near the sample tube. The thermal mass element may be separable from the housing, and/or the sample tube may be separable from the thermal mass element.

公开(公告)号：US11903970B2

公开(公告)日：2024-02-20

申请号：US17132634

申请日：2020-12-23

Applicant: Regenexx, LLC

Inventor： Christopher J. Centeno ,  Neven Steinmetz ,  Ian Stemper ,  Dustin Berger

IPC: C12M1/00 ,  A61K35/19 ,  C12N5/078 ,  A61K45/06 ,  C12N5/00 ,  G01N33/86 ,  C12M1/42

CPC classification number: A61K35/19 ,  A61K45/06 ,  C12M47/06 ,  C12N5/0018 ,  C12N5/0644 ,  C12M35/04 ,  C12N2523/00 ,  G01N33/86

Abstract: Apparatus, kit and method embodiments are disclosed herein that provide for the production of a modified autologous platelet mixture at a patient bedside for contemporaneous reinjection to the patient using a platelet lysis apparatus. Representative platelet lysis apparatus may include a housing supporting a sample tube and a thermal mass element connected to or near the sample tube. The thermal mass element may be separable from the housing, and/or the sample tube may be separable from the thermal mass element.

公开(公告)号：US20190025162A1

公开(公告)日：2019-01-24

申请号：US16137371

申请日：2018-09-20

Applicant: Regenexx, LLC

Inventor： Christopher J. Centeno ,  Brian Leach ,  Ryan Dregalla ,  Patrick Reischling

IPC: G01N1/14 ,  B01D21/26 ,  A61M1/36 ,  A61B5/153 ,  A61B5/15 ,  B01L3/00

Abstract: Apparatus, systems and methods for processing a blood sample. One embodiment includes an isolation container having at least one sidewall defining an interior volume. The interior volume includes a medial reservoir in fluid communication with proximal and distal reservoirs. The diameter of the medial reservoir is less than the diameter of the proximal and distal reservoirs. Therefore, the isolation container has an interior volume which is roughly hour-glass shaped with the medial reservoir being a substantially narrowed portion or channel between two wider portions. The isolation container is configured such that the buffy coat layer of fractionated blood will be located within, or may be manipulated to be with the medial reservoir.

公开(公告)号：US20240245724A1

公开(公告)日：2024-07-25

申请号：US18414832

申请日：2024-01-17

Applicant: Regenexx, LLC

Inventor： Christopher J. Centeno ,  Neven Steinmetz ,  Ian Stemper ,  Dustin Berger

IPC: A61K35/19 ,  A61K45/06 ,  C12M1/00 ,  C12M1/42 ,  C12N5/00 ,  C12N5/078 ,  G01N33/86

CPC classification number: A61K35/19 ,  A61K45/06 ,  C12M47/06 ,  C12N5/0018 ,  C12N5/0644 ,  C12M35/04 ,  C12N2523/00 ,  G01N33/86

Abstract: Apparatus, kit and method embodiments are disclosed herein that provide for the production of a modified autologous platelet mixture at a patient bedside for contemporaneous reinjection to the patient using a platelet lysis apparatus. Representative platelet lysis apparatus may include a housing supporting a sample tube and a thermal mass element connected to or near the sample tube. The thermal mass element may be separable from the housing, and/or the sample tube may be separable from the thermal mass element.