公开(公告)号：US11147837B2

公开(公告)日：2021-10-19

申请号：US15256086

申请日：2016-09-02

申请人： Regents of the University of Minnesota ,  Intima Bioscience, Inc. ,  The United States of America, as represented by the Secretary, Department of Health and Human Services

发明人： Branden Moriarity ,  Beau Webber ,  Modassir Choudhry ,  R. Scott McIvor ,  David Largaespada ,  Steven A. Rosenberg ,  Douglas C. Palmer ,  Nicholas P. Restifo

IPC分类号： A61K35/17 ,  C07K14/715 ,  C12N15/113 ,  C07K14/47 ,  C07K14/725 ,  C12N5/0783 ,  C07K14/705 ,  C12N15/90 ,  C12N9/22 ,  C12N9/96 ,  C12N15/87

摘要： Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.

公开(公告)号：US20200306309A1

公开(公告)日：2020-10-01

申请号：US16900363

申请日：2020-06-12

申请人： Regents of the University of Minnesota ,  Intima Bioscience, Inc. ,  The U.S.A. as Represented by the Secretary, Department of Health and Human Services

发明人： Branden Moriarity ,  Beau Webber ,  David Largaespada ,  Modassir Choudhry ,  Steven A. Rosenberg

IPC分类号： A61K35/17 ,  C07K14/715 ,  C12N15/113 ,  C07K14/47 ,  C07K14/725 ,  C12N5/0783 ,  C07K14/705 ,  C12N15/90 ,  C12N9/22 ,  C12N9/96

摘要： Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.

公开(公告)号：US20170067021A1

公开(公告)日：2017-03-09

申请号：US15256086

申请日：2016-09-02

申请人： Regents of the University of Minnesota ,  Intima Bioscience, Inc.

发明人： Branden Moriarity ,  Beau Webber ,  Modassir Choudhry ,  R. Scott McIvor ,  David Largaespada

IPC分类号： C12N5/0783 ,  C07K14/725 ,  A61K35/17 ,  C07K14/705

CPC分类号： A61K35/17 ,  C07K14/4718 ,  C07K14/70503 ,  C07K14/7051 ,  C07K14/70521 ,  C07K14/7158 ,  C12N5/0636 ,  C12N9/22 ,  C12N9/96 ,  C12N15/113 ,  C12N15/87 ,  C12N15/907 ,  C12N2310/20 ,  C12N2510/00 ,  C12N2800/80 ,  Y02A50/463

摘要： Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.

摘要翻译： 公开了用于治疗癌症的转基因组合物，例如非病毒载体和T细胞。 还公开了制备和使用转基因组合物治疗癌症的方法。

公开(公告)号：US11925664B2

公开(公告)日：2024-03-12

申请号：US16900368

申请日：2020-06-12

申请人： Regents of the University of Minnesota ,  Intima Bioscience, Inc. ,  The U.S.A., as Represented by the Secretary, Department of Health and Human Services

发明人： Branden Moriarity ,  Beau Webber ,  David Largaespada ,  Modassir Choudhry ,  Steven A. Rosenberg

IPC分类号： A61K48/00 ,  A61K35/17 ,  C07K14/47 ,  C07K14/705 ,  C07K14/715 ,  C07K14/725 ,  C12N5/0783 ,  C12N9/22 ,  C12N9/96 ,  C12N15/07 ,  C12N15/113 ,  C12N15/90 ,  C12N15/87

CPC分类号： A61K35/17 ,  C07K14/4718 ,  C07K14/70503 ,  C07K14/7051 ,  C07K14/7158 ,  C12N5/0636 ,  C12N9/22 ,  C12N9/96 ,  C12N15/113 ,  C12N15/907 ,  C12N15/87 ,  C12N2310/20 ,  C12N2510/00

摘要： Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.

公开(公告)号：US20220125843A1

公开(公告)日：2022-04-28

申请号：US17478615

申请日：2021-09-17

申请人： Regents of the University of Minnesota ,  Intima Bioscience, Inc. ,  The United States of America, as represented by the Secretary, Department of Health and Human Servic

发明人： Branden Moriarity ,  Beau Webber ,  Modassir Choudhry ,  R. Scott McIvor ,  David Largaespada ,  Steven A. Rosenberg ,  Douglas C. Palmer ,  Nicholas P. Restifo

IPC分类号： A61K35/17 ,  C07K14/47 ,  C12N9/22 ,  C12N9/96 ,  C07K14/725 ,  C12N15/90 ,  C07K14/715 ,  C12N15/113 ,  C07K14/705 ,  C12N5/0783 ,  C12N15/87

摘要： Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.

公开(公告)号：US11583556B2

公开(公告)日：2023-02-21

申请号：US17003081

申请日：2020-08-26

申请人： Regents of the University of Minnesota ,  Intima Bioscience, Inc. ,  The U.S.A., as represented by the Secretary, Department of Health and Human Services

发明人： Branden Moriarity ,  Beau Webber ,  Modassir Choudhry ,  R. Scott McIvor ,  David Largaespada ,  Steven A. Rosenberg ,  Douglas C. Palmer ,  Nicholas P. Restifo

IPC分类号： C12N5/00 ,  A61K35/17 ,  C07K14/715 ,  C12N15/113 ,  C07K14/47 ,  C07K14/725 ,  C12N5/0783 ,  C07K14/705 ,  C12N15/90 ,  C12N9/22 ,  C12N9/96 ,  C12N15/87

摘要： Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.