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    ANTIMICROBIAL PROTEIN
    7.
    发明申请
    ANTIMICROBIAL PROTEIN 有权
    抗微生物蛋白

    公开(公告)号：US20160052978A1

    公开(公告)日：2016-02-25

    申请号：US13879151

    申请日：2011-10-12

    申请人： Alexandra Carreira ,  Ricardo Manuel De Seixas Boavida Ferreira ,  Sara Alexandra Valadas Da Silva Monteiro

    发明人： Alexandra Carreira ,  Ricardo Manuel De Seixas Boavida Ferreira ,  Sara Alexandra Valadas Da Silva Monteiro

    IPC分类号： C07K14/415 ,  A01N47/40 ,  A23L3/3463 ,  A61K38/16

    摘要： The inventors provide a composition comprising an antimicrobial polypeptide comprising Blad or an active variant thereof for use in a method of treatment of the human or animal body by therapy or prophylaxis, such as for use in a method of treating or preventing an infection in or on a subject by a microorganism. Also provided is the use of a composition comprising an antimicrobial polypeptide comprising Blad or an active variant thereof to kill, or inhibit the growth of, a microorganism that is pathogenic to a human or an animal at a site that is not on or in the human or animal body.

    摘要翻译： 发明人提供了包含包含Blad或其活性变体的抗微生物多肽的组合物，其用于通过治疗或预防治疗人或动物体的方法，例如用于治疗或预防感染的方法 微生物的受试者。 还提供了包含包含Blad或其活性变体的抗微生物多肽的组合物在不在人或在人体中的位点上杀死或抑制对人或动物致病的微生物的生长的用途 或动物体。

    Use of chelating agent and peptide antimicrobial compounds
    8.
    发明授权
    Use of chelating agent and peptide antimicrobial compounds 有权

    公开(公告)号：US10265376B2

    公开(公告)日：2019-04-23

    申请号：US13879169

    申请日：2011-10-12

    申请人： Alexandra Manuela Lourenço Carreira ,  Ricardo Manuel De Seixas Boavida Ferreira ,  Sara Alexandra Valadas Da Silva Monteiro

    发明人： Alexandra Manuela Lourenço Carreira ,  Ricardo Manuel De Seixas Boavida Ferreira ,  Sara Alexandra Valadas Da Silva Monteiro

    IPC分类号： A61K38/16 ,  A01N65/20 ,  A01N37/44

    摘要： The inventors provide the use of a chelating agent and an antimicrobial agent that is effective against a plant pathogenic microorganism to inhibit the growth of and/or kill a plant pathogenic microorganism on a plant; the use of a chelating agent to increase the activity of an antimicrobial that is effective against a plant pathogenic microorganism; a method of inhibiting the growth of and/or killing a plant pathogenic microorganism comprising administering to a plant in need thereof a chelating agent and an antimicrobial agent that is effective against a plant pathogenic microorganism; and a method of increasing the activity of an antimicrobial that is effective against a plant pathogenic microorganism comprising using said antimicrobial with a chelating agent. Also provided is a composition comprising a chelating agent and an antimicrobial agent that is effective against a plant pathogenic microorganism, use of said composition to inhibit the growth of and/or kill a plant pathogenic microorganism on a plant, and a method of inhibiting the growth of and/or killing a plant pathogenic microorganism comprising administering to a plant in need thereof said composition. Further provided is the use of a composition comprising an antimicrobial polypeptide comprising Blad or an active variant thereof to kill, or inhibit the growth of a plant pathogenic bacterium on a plant, and a method of killing, or inhibiting the growth of a plant pathogenic bacterium on a plant, said method comprising administering to said plant a composition comprising an effective amount of an antimicrobial polypeptide comprising Blad or an active variant thereof.

    USE OF CHELATING AGENT AND PEPTIDE ANTIMICROBIAL COMPOUNDS
    10.
    发明申请
    USE OF CHELATING AGENT AND PEPTIDE ANTIMICROBIAL COMPOUNDS 审中-公开
    使用螯合剂和肽类抗微生物化合物

    公开(公告)号：US20130288954A1

    公开(公告)日：2013-10-31

    申请号：US13879169

    申请日：2011-10-12

    申请人： Alexandra Manuela Lourenço Carreira ,  Ricardo Manuel De Seixas Boavida Ferreira ,  Sara Alexandra Valadas Da Silva Monteiro

    发明人： Alexandra Manuela Lourenço Carreira ,  Ricardo Manuel De Seixas Boavida Ferreira ,  Sara Alexandra Valadas Da Silva Monteiro

    IPC分类号： A61K38/16

    CPC分类号： A61K38/16 ,  A01N37/44 ,  A01N65/20 ,  A01N2300/00 ,  A01N65/00

    摘要： The inventors provide the use of a chelating agent and an antimicrobial agent that is effective against a plant pathogenic microorganism to inhibit the growth of and/or kill a plant pathogenic microorganism on a plant; the use of a chelating agent to increase the activity of an antimicrobial that is effective against a plant pathogenic microorganism; a method of inhibiting the growth of and/or killing a plant pathogenic microorganism comprising administering to a plant in need thereof a chelating agent and an antimicrobial agent that is effective against a plant pathogenic microorganism; and a method of increasing the activity of an antimicrobial that is effective against a plant pathogenic microorganism comprising using said antimicrobial with a chelating agent. Also provided is a composition comprising a chelating agent and an antimicrobial agent that is effective against a plant pathogenic microorganism, use of said composition to inhibit the a growth of and/or kill a plant pathogenic microorganism on a plant, and a method of inhibiting the growth of and/or killing a plant pathogenic microorganism comprising administering to a plant in need thereof said composition. Further provided is the use of a composition comprising an antimicrobial polypeptide comprising Blad or an active variant thereof to kill, or inhibit the growth of a plant pathogenic bacterium on a plant, and a method of killing, or inhibiting the growth of a plant pathogenic bacterium on a plant, said method comprising administering to said plant a composition comprising an effective amount of an antimicrobial polypeptide comprising Blad or an active variant thereof.

    摘要翻译： 发明人提供了对植物病原微生物有效抑制植物上植物病原微生物生长和/或杀死植物病原微生物的螯合剂和抗微生物剂的用途; 使用螯合剂来增加对植物病原微生物有效的抗微生物剂的活性; 抑制植物病原微生物生长和/或杀死植物病原微生物的方法，包括向有需要的植物施用有效对植物病原微生物的螯合剂和抗微生物剂; 以及增加对植物病原微生物有效的抗微生物活性的方法，其包括用螯合剂使用所述抗微生物剂。 还提供了一种组合物，其包含对植物病原微生物有效的螯合剂和抗微生物剂，所述组合物用于抑制植物上植物病原微生物生长和/或杀死植物病原微生物的方法，以及抑制植物病原微生物的方法 生长和/或杀死植物致病微生物，其包括向有需要的植物施用所述组合物。 还提供了包含包含Blad或其活性变体的抗微生物多肽的组合物在植物上杀死或抑制植物致病菌生长的组合物的使用，以及杀死或抑制植物致病菌生长的方法 所述方法包括向所述植物施用包含有效量的包含Blad或其活性变体的抗微生物多肽的组合物。