PHAGE DISPLAYED CELL BINDING PEPTIDES
    1.
    发明申请
    PHAGE DISPLAYED CELL BINDING PEPTIDES 有权
    PHAGE显示细胞结合肽

    公开(公告)号:US20100137225A1

    公开(公告)日:2010-06-03

    申请号:US12701397

    申请日:2010-02-05

    IPC分类号: A61K38/08 C07K1/107 A61P43/00

    摘要: This disclosure provides the construction, expression, and selection of the mutated genes that encode novel Trp cage polypeptides with desirable binding properties, as well as the novel Trp cage polypeptides themselves. The substances or targets bound by these novel Trp cage polypeptides may be but need not be proteins or polypeptides. Targets may include other biological or synthetic macromolecules as well as other organic and inorganic substances. Further, targets may also include a single or multiple cell or tissue types. The present invention achieves genetic variants of Trp cage-encoding nucleic acids through controlled random mutagenesis of the nucleic acids yielding a mixture of Trp cage polypeptides that are capable of binding targets.

    摘要翻译: 本公开提供编码具有所需结合特性的新型Trp笼多肽的突变基因的构建,表达和选择,以及新型Trp笼多肽本身。 由这些新型Trp笼多肽结合的物质或靶标可能不一定是蛋白质或多肽。 目标可以包括其他生物或合成大分子以及其它有机和无机物质。 此外,靶也可以包括单个或多个细胞或组织类型。 本发明通过控制随机诱变获得Trp笼编码核酸的遗传变体,产生能够结合靶标的Trp笼多肽的混合物。

    Phage displayed cell binding peptides
    2.
    发明授权
    Phage displayed cell binding peptides 有权
    噬菌体展示细胞结合肽

    公开(公告)号:US07772189B2

    公开(公告)日:2010-08-10

    申请号:US12701397

    申请日:2010-02-05

    IPC分类号: A61K38/00 C07K7/06

    摘要: This disclosure provides the construction, expression, and selection of the mutated genes that encode novel Trp cage polypeptides with desirable binding properties, as well as the novel Trp cage polypeptides themselves. The substances or targets bound by these novel Trp cage polypeptides may be but need not be proteins or polypeptides. Targets may include other biological or synthetic macromolecules as well as other organic and inorganic substances. Further, targets may also include a single or multiple cell or tissue types. The present invention achieves genetic variants of Trp cage-encoding nucleic acids through controlled random mutagenesis of the nucleic acids yielding a mixture of Trp cage polypeptides that are capable of binding targets.

    摘要翻译: 本公开提供编码具有所需结合特性的新型Trp笼多肽的突变基因的构建,表达和选择,以及新型Trp笼多肽本身。 由这些新型Trp笼多肽结合的物质或靶标可能不一定是蛋白质或多肽。 目标可以包括其他生物或合成大分子以及其它有机和无机物质。 此外,靶还可以包括单个或多个细胞或组织类型。 本发明通过控制随机诱变获得Trp笼编码核酸的遗传变体,产生能够结合靶标的Trp笼多肽的混合物。

    Phage displayed cell binding peptides
    4.
    发明授权
    Phage displayed cell binding peptides 失效
    噬菌体展示细胞结合肽

    公开(公告)号:US07704953B2

    公开(公告)日:2010-04-27

    申请号:US11627863

    申请日:2007-01-26

    IPC分类号: A61K38/00

    摘要: The present disclosure relates to the construction, expression, and selection of genes that encode novel Trp cage polypeptides with desirable cell and/or tissue binding properties, as well as the novel Trp cage polypeptides themselves. A polypeptide of this disclosure may contain all or part of amino acid sequence AAADX1YX2QWLX3X4X5GPX6SGRPPPX7 (SEQ ID NO: 4), wherein Xn represents an amino acid found in position n, the polypeptide comprising a tryptophan cage (Trp cage).

    摘要翻译: 本公开涉及编码具有期望的细胞和/或组织结合特性的新型Trp笼多肽的基因的构建,表达和选择,以及新型Trp笼多肽本身。 本公开的多肽可以包含氨基酸序列AAADX1YX2QWLX3X4X5GPX6SGRPPPX7(SEQ ID NO:4)的全部或部分,其中Xn表示位置n中发现的氨基酸,所述多肽包含色氨酸笼(Trp笼)。

    Luminous Water Wall Display
    7.
    发明申请
    Luminous Water Wall Display 有权
    发光水墙显示

    公开(公告)号:US20140240958A1

    公开(公告)日:2014-08-28

    申请号:US14167982

    申请日:2014-01-29

    IPC分类号: F21S10/00

    摘要: A water display is described having a lighting array emanating light that travels through a wall. Water flows down the wall to vary the appearance of the light that shines through the wall. The flow of water and particular lights being turned on and off may be controlled. Dramatic visual effects are provided including the appearance of moving art.

    摘要翻译: 描述了一种水显示器,其具有发出穿过壁的光的照明阵列。 水流向墙壁,以改变通过墙壁照射的光线的外观。 可以控制水的流动和特定的灯被打开和关闭。 提供戏剧性的视觉效果,包括移动艺术的外观。

    Water Shooter Device and Associated Visual Water Effects
    8.
    发明申请
    Water Shooter Device and Associated Visual Water Effects 审中-公开
    水射击装置和相关的视觉水影响

    公开(公告)号:US20140203101A1

    公开(公告)日:2014-07-24

    申请号:US14134983

    申请日:2013-12-19

    IPC分类号: B05B17/08

    摘要: A device to shoot water into the air for a water display is described. The configuration of the shooter allows a stream of water to be shot out that contains reduced or no air exiting the device with the water, which provides a non-frothy appearance. The device may control the velocity of the water being shot by the device so that unique visual effects may be achieved, including an effect where a volume of water is suspended in the air.

    摘要翻译: 描述了将水喷入空气中以进行水显示的装置。 射击者的配置允许喷射水流,其中包含减少的或没有空气与水一起离开设备,这提供了不起泡的外观。 该装置可以控制由装置射出的水的速度,使得可以实现独特的视觉效果,包括一定量的水悬浮在空气中的效果。

    Image projection on dynamic water mist screen
    9.
    发明授权
    Image projection on dynamic water mist screen 有权
    动态水雾屏幕上的图像投影

    公开(公告)号:US08511828B2

    公开(公告)日:2013-08-20

    申请号:US13172713

    申请日:2011-06-29

    IPC分类号: G03B21/53 G03B21/14

    摘要: A multimedia presentation system a projector to project images toward an audience. A plurality of nozzles are partially submerged in a body of water at locations between the projector and the audience. The plurality of nozzles are located at different distances from the projector. Each of the plurality of nozzles is arranged to produce a fan like water mist onto which the projector projects images. A controller is coupled to the projector and the plurality of nozzles. The controller causes the projector to project images and at least one of the plurality of nozzles to produce a water mist in a synchronized sequence such that the images appear at different distances from the projector at different times. The controller may further control the orientation of each nozzle to vary the distance by inclining the plane of the water mist relative to the surface of the body of water.

    摘要翻译: 一种多媒体演示系统,用于向观众投影图像的投影仪。 在投影机和观众之间的位置处,多个喷嘴部分地浸没在水体中。 多个喷嘴位于与投影仪不同的距离处。 多个喷嘴中的每一个布置成产生投影仪投影图像的风扇,如水雾。 控制器耦合到投影仪和多个喷嘴。 控制器使得投影仪投影图像和多个喷嘴中的至少一个以产生同步顺序的水雾,使得图像在不同时间出现在与投影仪不同的距离处。 控制器可以通过使水雾的平面相对于水体的表面倾斜来进一步控制每个喷嘴的取向以改变距离。