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    Polypeptide analogs of apolipoprotein E, diagnostic systems and methods using the analogs
    3.
    发明授权
    Polypeptide analogs of apolipoprotein E, diagnostic systems and methods using the analogs 失效
    载脂蛋白E的多肽类似物，诊断系统和使用类似物的方法

    公开(公告)号：US5473039A

    公开(公告)日：1995-12-05

    申请号：US805193

    申请日：1991-12-09

    申请人： Cheryl A. Dyer ,  Linda K. Curtiss ,  Richard Smith

    发明人： Cheryl A. Dyer ,  Linda K. Curtiss ,  Richard Smith

    IPC分类号： A61K38/00 ,  C07K14/775 ,  C07K16/18 ,  C07K7/00 ,  C07K7/06 ,  C07K7/08

    CPC分类号： C07K16/18 ,  C07K14/775 ,  A61K38/00

    摘要： The present invention contemplates a multimeric polypeptide capable of mimicking the ability of apo E to induce differentiated cellular function. The repeating unit of the polypeptide has an amino acid residue sequence corresponding to that represented by the formula LRXLRKRLLX. Also contemplated is a method for treating hypercholesterolemia in a patient, which method comprises administering to the patient an LDL plasma concentration-reducing amount of the polypeptide. Described as well, is the use of the polypeptide in preparing diagnostic antibodies, and their use in diagnostic systems and methods for detecting apo E antigens in vascular body fluids.

    摘要翻译： 本发明考虑了能够模拟载脂蛋白E诱导分化的细胞功能的能力的多聚体多肽。 多肽的重复单元具有与由式LRXLRKRLLX表示的氨基酸残基相对应的氨基酸残基。 还考虑了用于治疗患者的高胆固醇血症的方法，该方法包括向患者施用LDL血浆浓度降低量的多肽。 还描述了多肽在制备诊断抗体中的用途，以及它们在用于检测血管体液中的载脂蛋白E抗原的诊断系统和方法中的用途。

    Polypeptide analogs of apolipoprotein E
    4.
    发明授权
    Polypeptide analogs of apolipoprotein E 失效
    载脂蛋白E的多肽类似物

    公开(公告)号：US5182364A

    公开(公告)日：1993-01-26

    申请号：US485158

    申请日：1990-02-26

    申请人： Cheryl A. Dyer ,  Linda K. Curtiss ,  Richard Smith

    发明人： Cheryl A. Dyer ,  Linda K. Curtiss ,  Richard Smith

    IPC分类号： A61K38/00 ,  C07K14/775 ,  C07K16/18

    CPC分类号： C07K14/775 ,  C07K16/18 ,  A61K38/00

    摘要： The present invention contemplates a method for treating hypercholesterolemia in a patient, which method comprises administering to the patient an LDL plasma concentration-reducing amount of a multimeric polypeptide capable of binding the LDL receptor. THe repeating unit of the polypeptide has an amino acid residue sequence corresponding to that represented by the formula LRKLRKRLLRDADDL.

    摘要翻译： 本发明涉及用于治疗患者的高胆固醇血症的方法，该方法包括向患者施用LDL血浆浓度降低量的能够结合LDL受体的多聚体多肽。 所述多肽的重复单元具有对应于由式LRKLRKRLLRDADDL表示的氨基酸残基序列。

    Bearing Grease
    8.
    发明申请
    Bearing Grease 审中-公开
    轴承润滑脂

    公开(公告)号：US20150377294A1

    公开(公告)日：2015-12-31

    申请号：US14675898

    申请日：2015-04-01

    申请人： Richard Smith ,  Asley Crowther ,  Jesse Harries Graeter ,  Scott Macindoe ,  Michael Ulfert Hornemann

    发明人： Richard Smith ,  Asley Crowther ,  Jesse Harries Graeter ,  Scott Macindoe ,  Michael Ulfert Hornemann

    IPC分类号： F16C33/66 ,  B08B3/10 ,  B01D35/02 ,  B08B3/02

    CPC分类号： F16C33/6622 ,  B01D35/02 ,  B08B3/02 ,  B08B3/10 ,  B08B9/00 ,  F03D80/50 ,  F03D80/55 ,  F03D80/70 ,  F16C2360/31

    摘要： A method is disclosed for replacing grease in a main bearing of a wind turbine, the main bearing located in a housing and the housing having least one cover plate. the bearing cover plate is removed from the housing, grease is manually removed from the main bearing, and a flushing cover is installed on the housing in place of the bearing cover plate. The flushing cover has at least two parts, the parts fitting around the main shaft, and each part having a seal so that when its attached to the bearing housing, the flushing cover forms a seal with the main shaft. The flushing cover has holes allowing access to the main bearing, and a solvent or oil is sprayed via one of the holes onto the main bearing to remove grease, the remaining holes being sealed by a removable plug. Solvent or oil is pumped out of the housing via a port at the bottom of the housing or flushing cover. The process is repeated for each hole, and the flushing cover removed, the main bearing packed with grease, and the bearing cover plate re-affixed. The spraying step involves pumping solvent or oil from a reservoir to the spray nozzle, and the step of pumping solvent or oil out of the bearing housing involves pumping solvent or oil to the reservoir via a return hose. This means that the solvent or oil is recycled during the replacing of the grease. An apparatus for flushing grease from a main bearing of a wind turbine is also described.

    摘要翻译： 公开了一种用于更换风力涡轮机的主轴承中的润滑脂的方法，位于壳体中的主轴承和具有至少一个盖板的壳体。 将轴承盖板从壳体中取出，从主轴承上手动取出润滑脂，并且将外壳上的冲洗盖安装在轴承盖板上。 冲洗盖具有至少两个部件，部件围绕主轴安装，每个部件具有密封件，使得当其附接到轴承壳体时，冲洗盖与主轴形成密封。 冲洗盖具有允许进入主轴承的孔，并且通过一个孔将溶剂或油喷射到主轴承上以除去油脂，剩余的孔被可移除的塞子密封。 溶剂或油通过外壳或冲洗盖底部的端口从外壳中抽出。 每个孔重复该过程，拆下冲洗盖，装有油脂的主轴承和轴承盖板重新固定。 喷射步骤包括将溶剂或油从储存器泵送到喷嘴，并且将溶剂或油抽出轴承壳体的步骤包括通过返回软管将溶剂或油泵送到储存器。 这意味着溶剂或油在更换润滑脂期间被循环使用。 还描述了用于从风力涡轮机的主轴承冲洗润滑脂的装置。

    Burner for a gas turbine and method for feeding a gaseous fuel in a burner
    9.
    发明授权
    Burner for a gas turbine and method for feeding a gaseous fuel in a burner 有权
    用于燃气轮机的燃烧器和用于在燃烧器中供给气态燃料的方法

    公开(公告)号：US08522527B2

    公开(公告)日：2013-09-03

    申请号：US12690283

    申请日：2010-01-20

    申请人： Adnan Eroglu ,  Douglas Anthony Pennell ,  Johannes Buss ,  Richard Smith

    发明人： Adnan Eroglu ,  Douglas Anthony Pennell ,  Johannes Buss ,  Richard Smith

    IPC分类号： F02K3/10 ,  F02C1/06 ,  F02C1/00 ,  F02C7/22

    CPC分类号： F23R3/286 ,  F23R3/34 ,  F23R2900/03341

    摘要： A burner (1) for a gas turbine includes a duct (2) enclosing a plurality of vortex generators (3) and, downstream of them, a lance (5) provided with nozzles (6) for injecting a gaseous fuel. The burner (1) also includes a mixer (7) for diluting and mixing the gaseous fuel with air to form a mixture. The mixer (7) is connected to the nozzles (6) for feeding them with the mixture. A method includes feeding the gaseous fuel in the burner (1).

    摘要翻译： 一种用于燃气轮机的燃烧器（1）包括封闭多个涡流发生器（3）的管道（2），并且在其下游设置有喷枪（5），喷枪（6）用于喷射气态燃料。 燃烧器（1）还包括用于将气体燃料稀释和混合以形成混合物的混合器（7）。 混合器（7）连接到喷嘴（6），用于将它们供给到混合物中。 一种方法包括将燃料（1）中的气态燃料进料。

    Systems and methods for tracking and authenticating goods
    10.
    发明申请
    Systems and methods for tracking and authenticating goods 有权
    跟踪和认证货物的系统和方法

    公开(公告)号：US20130022238A1

    公开(公告)日：2013-01-24

    申请号：US13507320

    申请日：2012-06-21

    申请人： Stephen M. Wood ,  Richard Smith ,  David Bear ,  George Kechter ,  Conor O'Neill

    发明人： Stephen M. Wood ,  Richard Smith ,  David Bear ,  George Kechter ,  Conor O'Neill

    IPC分类号： G06K9/78 ,  G06K19/06

    CPC分类号： G06K19/06056 ,  G06K5/00 ,  G06K9/00577 ,  G06K19/06 ,  G06Q30/0185 ,  G07D7/2033

    摘要： Systems and methods for identifying, tracking, tracing and determining the authenticity of a good include an imaging system, a database, and an authentication center. The imaging system is configured to capture an image of a unique signature associated with a good. The unique signature can be, for example, a random structure or pattern unique to the particular good. The imaging system is configured to process the image to identify at least one metric that distinguishes the unique signature from unique signatures of other goods. The database is configured to receive information related to the good and its unique signature from the imaging system, and to store the information therein. The authentication center is configured to analyze the field image with respect to the information stored in the database to determine whether the unique signature in the field image is a match to the captured image stored in the database.

    摘要翻译： 用于识别，跟踪，跟踪和确定商品的真实性的系统和方法包括成像系统，数据库和认证中心。 成像系统被配置为捕获与商品相关联的唯一签名的图像。 独特的签名可以是例如特定商品独特的随机结构或图案。 成像系统被配置为处理图像以识别将唯一签名与其他商品的唯一签名区分开的至少一个度量。 数据库被配置为从成像系统接收与该品牌及其唯一签名相关的信息，并且将该信息存储在其中。 认证中心被配置为相对于存储在数据库中的信息来分析场图像，以确定场图像中的唯一签名是否与存储在数据库中的捕获图像相匹配。