公开(公告)号：US06209538B1

公开(公告)日：2001-04-03

申请号：US09042656

申请日：1998-03-17

申请人： Robert A. Casper ,  Frank A. Leith ,  David L. Gardner ,  John M. Snow ,  Zachary W. Lyon ,  David S. Farrar

发明人： Robert A. Casper ,  Frank A. Leith ,  David L. Gardner ,  John M. Snow ,  Zachary W. Lyon ,  David S. Farrar

IPC分类号： A61M1600

CPC分类号： A61M15/0028 ,  A61M11/001 ,  A61M11/002 ,  A61M15/003 ,  A61M15/0033 ,  A61M15/0065 ,  A61M15/0091 ,  A61M15/0093 ,  A61M2202/064

摘要： An inhalation-activated inhalator having a primary inhalation passage and a secondary inhalation passage disposed in communication with the primary inhalation passage and a source of medicament. The primary inhalation passage has airflow inhibiting mechanism connected to a blocking plate positioned to selectively block fluid flow in the secondary inhalation passage. As the user's inhalation reaches a defined rate, the flow inhibiting mechanism restricts flow through the primary inhalation passage and moves the blocking plate to enable airflow through the secondary passage. Thus, as the user achieves a desired inhalation rate, the medicament is provided through the secondary inhalation passage, thereby optimizing the delivery of medicament to the lungs.

摘要翻译： 具有主要吸入通道和与主要吸入通道连通的辅助吸入通道和药物源的吸入激活吸入器。 主要吸入通道具有连接到阻挡板的气流抑制机构，该阻挡板定位成选择性地阻挡二次吸入通道中的流体流动。 当用户的吸入达到限定的速度时，流动抑制机构限制通过主要吸入通道的流动并移动阻挡板以使气流能够通过次级通道。 因此，当使用者达到期望的吸入速率时，通过二次吸入通道提供药物，从而优化药物向肺的递送。

公开(公告)号：US06561186B2

公开(公告)日：2003-05-13

申请号：US09995923

申请日：2001-11-27

申请人： Robert A. Casper ,  Frank A. Leith ,  David L. Gardner ,  John M. Snow ,  Zachary W. Lyon ,  David S. Farrar

发明人： Robert A. Casper ,  Frank A. Leith ,  David L. Gardner ,  John M. Snow ,  Zachary W. Lyon ,  David S. Farrar

IPC分类号： A61M1500

CPC分类号： A61M15/0028 ,  A61M11/001 ,  A61M11/002 ,  A61M15/003 ,  A61M15/0033 ,  A61M15/0065 ,  A61M15/0091 ,  A61M15/0093 ,  A61M2202/064

摘要： An inhalation-activated inhalator having a primary inhalation passage and a secondary inhalation passage disposed in communication with the primary inhalation passage and a source of medicament. The primary inhalation passage has airflow inhibiting mechanism connected to a blocking plate positioned to selectively block fluid flow in the secondary inhalation passage. As the user's inhalation reaches a defined rate, the flow inhibiting mechanism restricts flow through the primary inhalation passage and moves the blocking plate to enable airflow through the secondary passage. Thus, as the user achieves a desired inhalation rate, the medicament is provided through the secondary inhalation passage, thereby optimizing the delivery of medicament to the lungs.

公开(公告)号：US06550477B1

公开(公告)日：2003-04-22

申请号：US09492714

申请日：2000-01-27

申请人： Robert A. Casper ,  Frank A. Leith ,  David L. Gardner ,  John M. Snow ,  Zachary W. Lyon ,  David S. Farrar

发明人： Robert A. Casper ,  Frank A. Leith ,  David L. Gardner ,  John M. Snow ,  Zachary W. Lyon ,  David S. Farrar

IPC分类号： A61M1600

CPC分类号： A61M15/0028 ,  A61M11/001 ,  A61M11/002 ,  A61M15/003 ,  A61M15/0033 ,  A61M15/0065 ,  A61M15/0091 ,  A61M15/0093 ,  A61M2202/064

摘要： An inhalation-activated inhalator having a primary inhalation passage and a secondary inhalation passage disposed in communication with the primary inhalation passage and a source of medicament. The primary inhalation passage has airflow inhibiting mechanism connected to a blocking plate positioned to selectively block fluid flow in the secondary inhalation passage. As the user's inhalation reaches a defined rate, the flow inhibiting mechanism restricts flow through the primary inhalation passage and moves the blocking plate to enable airflow through the secondary passage. Thus, as the user achieves a desired inhalation rate, the medicament is provided through the secondary inhalation passage, thereby optimizing the delivery of medicament to the lungs.

公开(公告)号：US5577837A

公开(公告)日：1996-11-26

申请号：US445013

申请日：1995-05-19

申请人： Paul M. Martin ,  Gregory J. Graham ,  David S. Farrar ,  Stephen R. Faigley

发明人： Paul M. Martin ,  Gregory J. Graham ,  David S. Farrar ,  Stephen R. Faigley

IPC分类号： B01F11/00 ,  C12M1/00 ,  C12M1/02 ,  B01F15/06

CPC分类号： C12M41/14 ,  B01F11/0068 ,  C12M27/16 ,  C12M29/04 ,  C12M41/48

摘要： A console shaker which includes a shaker device mounted within a temperature and lighting controlled chamber and an air jacket which completely surrounds the chamber and also provides substantially laminar, HEPA-filtered air flow through the chamber in one direction. A refrigeration device and a heating device either cool or heat the air before it flows through the HEPA filter. The HEPA filter is mounted at the end of the chamber which defines an air inlet to the work chamber and an outlet is disposed at the opposite end of the chamber. The outlet end of the chamber receives air from both within the workspace of the chamber as well as from the front and rear air spaces of the air jacket. A microprocessor based control system provides an interface between the user and the various components for establishing the conditions within the chamber, such as shaker speed, temperature, time and lighting to be controlled by the user. To allow quick setting of the overall conditions or control parameters, the microprocessor based system allows one of a plurality of preset programs to be chosen by the user to set shaker speed, chamber temperature and time.

摘要翻译： 一种控制台振动器，其包括安装在温度和照明控制室内的振动器装置和完全围绕所述腔室的空气夹套，并且还在一个方向上提供通过所述腔室的基本上层状的经过HEPA过滤的气流。 一种制冷装置和一种加热装置可以在空气流过HEPA过滤器之前冷却或加热空气。 HEPA过滤器安装在室的端部，其限定了到工作室的空气入口，并且出口设置在室的相对端。 室的出口端在室的工作空间内以及从空气套的前后空气空间接收空气。 基于微处理器的控制系统提供用户和各种组件之间的接口，用于建立室内的状态，例如振动器速度，温度，时间和由用户控制的照明。 为了允许快速设置总体条件或控制参数，基于微处理器的系统允许用户选择多个预设程序中的一个来设定振动器速度，室温度和时间。