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    Medical Device Location Systems, Devices and Methods
    1.
    发明申请
    Medical Device Location Systems, Devices and Methods 有权

    公开(公告)号：US20120130228A1

    公开(公告)日：2012-05-24

    申请号：US12949663

    申请日：2010-11-18

    申请人： Robert D. Zellers ,  Peter E. Nelson ,  Charles W. Henry

    发明人： Robert D. Zellers ,  Peter E. Nelson ,  Charles W. Henry

    IPC分类号： A61B5/05

    CPC分类号： A61B5/062

    摘要： Methods, devices and systems for one or both of two- or three-dimensional location of the disposition of a sensor coil in a subject including: an array of electromagnetic drive coil sets, each set having two or three dimensionally oriented drive coils; a sensor coil being electromagnetically communicative with the array of electromagnetic drive coil sets; and, a system controller communicative with and adapted to energize one or more of the electromagnetic coils in the array of electromagnetic drive coil sets, the energizing of the one or more of the electromagnetic coils including one or more of energizing the coils singly, or in pairs of x-y and y-z or x-z coils, or in triplets of x-y-z coils while measuring the response of the sensor coil; whereby the system uses the measurements of the responses of the sensor coil to calculate the location and orientation of the sensor coil relative to said drive coil sets.

    Medical device location systems, devices and methods
    2.
    发明授权
    Medical device location systems, devices and methods 有权
    医疗设备定位系统，设备和方法

    公开(公告)号：US08391956B2

    公开(公告)日：2013-03-05

    申请号：US12949663

    申请日：2010-11-18

    申请人： Robert D. Zellers ,  Peter E. Nelson ,  Charles W. Henry

    发明人： Robert D. Zellers ,  Peter E. Nelson ,  Charles W. Henry

    IPC分类号： A61B5/05

    CPC分类号： A61B5/062

    摘要： Methods, devices and systems for one or both of two- or three-dimensional location of the disposition of a sensor coil in a subject including: an array of electromagnetic drive coil sets, each set having two or three dimensionally oriented drive coils; a sensor coil being electromagnetically communicative with the array of electromagnetic drive coil sets; and, a system controller communicative with and adapted to energize one or more of the electromagnetic coils in the array of electromagnetic drive coil sets, the energizing of the one or more of the electromagnetic coils including one or more of energizing the coils singly, or in pairs of x-y and y-z or x-z coils, or in triplets of x-y-z coils while measuring the response of the sensor coil; whereby the system uses the measurements of the responses of the sensor coil to calculate the location and orientation of the sensor coil relative to said drive coil sets.

    摘要翻译： 传感器线圈在被摄体中的二维或三维位置的一个或两个位置的方法，装置和系统，包括：电磁驱动线圈组阵列，每组具有二维或三维定向的驱动线圈; 传感器线圈与电磁驱动线圈组阵列电磁连接; 以及与电磁驱动线圈组阵列中的一个或多个电磁线圈通电且适于对电磁驱动线圈组的电磁线圈通电的系统控制器，一个或多个电磁线圈的激励包括单独激励线圈中的一个或多个，或者 一对xy和yz或xz线圈，或在xyz线圈的三元组中，同时测量传感器线圈的响应; 由此系统使用传感器线圈的响应的测量来计算传感器线圈相对于所述驱动线圈组的位置和取向。

    Medical Device Location Systems, Devices and Methods
    3.
    发明申请
    Medical Device Location Systems, Devices and Methods 有权
    医疗器械定位系统，设备和方法

    公开(公告)号：US20120130229A1

    公开(公告)日：2012-05-24

    申请号：US12949671

    申请日：2010-11-18

    申请人： Robert D. Zellers ,  Peter E. Nelson ,  Charles W. Henry

    发明人： Robert D. Zellers ,  Peter E. Nelson ,  Charles W. Henry

    IPC分类号： A61B5/05

    CPC分类号： A61B5/062

    摘要： Methods, devices and systems for one or both of two- or three-dimensional location of the disposition of a sensor coil in a subject including: an array of electromagnetic drive coil sets, each set having two or three dimensionally oriented drive coils; a sensor coil being electromagnetically communicative with the array of electromagnetic drive coil sets; and, a system controller communicative with and adapted to energize one or more of the electromagnetic coils in the array of electromagnetic drive coil sets, the energizing of the one or more of the electromagnetic coils including one or more of energizing the coils singly, or in pairs of x-y and y-z or x-z coils, or in triplets of x-y-z coils while measuring the response of the sensor coil; whereby the system uses the measurements of the responses of the sensor coil to calculate the location and orientation of the sensor coil relative to said drive coil sets.

    摘要翻译： 传感器线圈在被摄体中的二维或三维位置的一个或两个位置的方法，装置和系统，包括：电磁驱动线圈组阵列，每组具有二维或三维定向的驱动线圈; 传感器线圈与电磁驱动线圈组阵列电磁连接; 以及与电磁驱动线圈组阵列中的一个或多个电磁线圈通电且适于对电磁驱动线圈组的电磁线圈通电的系统控制器，一个或多个电磁线圈的激励包括单独激励线圈中的一个或多个，或者 一对xy和yz或xz线圈，或在xyz线圈的三元组中，同时测量传感器线圈的响应; 由此系统使用传感器线圈的响应的测量来计算传感器线圈相对于所述驱动线圈组的位置和取向。

    Medical device location systems, devices and methods
    4.
    发明授权
    Medical device location systems, devices and methods 有权

    公开(公告)号：US08380289B2

    公开(公告)日：2013-02-19

    申请号：US12949671

    申请日：2010-11-18

    申请人： Robert D. Zellers ,  Peter E. Nelson ,  Charles W. Henry

    发明人： Robert D. Zellers ,  Peter E. Nelson ,  Charles W. Henry

    IPC分类号： A61B5/05

    CPC分类号： A61B5/062

    摘要： Methods, devices and systems for one or both of two- or three-dimensional location of the disposition of a sensor coil in a subject including: an array of electromagnetic drive coil sets, each set having two or three dimensionally oriented drive coils; a sensor coil being electromagnetically communicative with the array of electromagnetic drive coil sets; and, a system controller communicative with and adapted to energize one or more of the electromagnetic coils in the array of electromagnetic drive coil sets, the energizing of the one or more of the electromagnetic coils including one or more of energizing the coils singly, or in pairs of x-y and y-z or x-z coils, or in triplets of x-y-z coils while measuring the response of the sensor coil; whereby the system uses the measurements of the responses of the sensor coil to calculate the location and orientation of the sensor coil relative to said drive coil sets.

    Noninvasive optical sensor for measuring near infrared light absorbing analytes
    6.
    发明授权
    Noninvasive optical sensor for measuring near infrared light absorbing analytes 失效
    用于测量近红外光吸收分析物的无创光学传感器

    公开(公告)号：US06802812B1

    公开(公告)日：2004-10-12

    申请号：US09917414

    申请日：2001-07-27

    申请人： Stephen D. Walker ,  John E. Repine ,  Charles W. Henry ,  Harry L. Valenta, Jr. ,  Peter E. Nelson ,  R. Dale Zellers

    发明人： Stephen D. Walker ,  John E. Repine ,  Charles W. Henry ,  Harry L. Valenta, Jr. ,  Peter E. Nelson ,  R. Dale Zellers

    IPC分类号： A61B500

    CPC分类号： A61B5/412 ,  A61B5/02028 ,  A61B5/0261 ,  A61B5/14553 ,  A61B5/413 ,  A61B5/7275 ,  A61B2562/028

    摘要： An optical sensor includes an optical source capable of being positioned on a tissue and emitting near infrared light into the tissue at a plurality of selected wavelengths, and a photodetector capable of detecting reflected light from the tissue. The photodetector being positioned on the tissue removed from the optical source but sufficiently close in proximity to the optical source to contact the same general tissue. The optical sensor further includes an oscillator coupled to the optical source and capable of activating the optical source to emit the near infrared light, and a modulator coupled to the oscillator and capable of controlling radio frequency modulation of the optical source to emit a radio frequency component that is used to measure the optical path length and absorbance of an analyte of interest within the tissue.

    摘要翻译： 光学传感器包括能够定位在组织上并以多个选定波长将近红外光发射到组织中的光源，以及能够检测来自组织的反射光的光电检测器。 光电检测器定位在从光源移除的组织上，但是在光源附近充分接近以接触相同的一般组织。 光学传感器还包括耦合到光源并且能够激活光源以发射近红外光的振荡器，以及耦合到振荡器并且能够控制光源的射频调制以发射射频分量的振荡器 其用于测量组织内感兴趣的分析物的光程长度和吸光度。

    LACTATE CONCENTRATION MEASUREMENT DEVICE
    8.
    发明申请
    LACTATE CONCENTRATION MEASUREMENT DEVICE 审中-公开
    LACTATE浓度测量装置

    公开(公告)号：US20090047177A1

    公开(公告)日：2009-02-19

    申请号：US11840528

    申请日：2007-08-17

    申请人： Stephen D. Walker ,  Devon J. Dallmann ,  Charles W. Henry ,  Peter E. Nelson ,  R. Dale Zellers ,  John E. Repine

    发明人： Stephen D. Walker ,  Devon J. Dallmann ,  Charles W. Henry ,  Peter E. Nelson ,  R. Dale Zellers ,  John E. Repine

    IPC分类号： G01N21/00 ,  G01N33/48

    CPC分类号： G01N21/314 ,  G01N21/35 ,  G01N2021/3166

    摘要： A lactate concentration measurement apparatus comprising a housing enclosing a sample chamber configured for holding a body fluid sample and measurement photo-optics that generate light and monitor light intensity along a plurality of optical paths in the sample chamber. The apparatus further comprises a plurality of optical filters aligned in respective optical paths of the optical path plurality comprising at least a first optical filter with light absorption by lactate and water and a second optical filter with light absorption to water alone. A logic determines lactate concentration based on a ratio of intensities detected at a first detector in an optical path intersected by the first optical filter and detected at a second detector in an optical path intersected by the second optical filter.

    摘要翻译： 一种乳酸盐浓度测量装置，包括：壳体，其包围被构造成用于保持体液样本的样本室，以及测量光学光学器件，其产生光并沿着样本室中的多个光路监测光强度。 该装置还包括多个光学滤光器，该多个光学滤光器在光路的各个光路中排列成多个，至少包括具有乳酸和水的光吸收的第一滤光器以及仅对水单独吸收光的第二滤光器。 逻辑根据在与第一滤光器相交的光路中的第一检测器检测到的强度的比值确定乳酸浓度，并且在与第二滤光器相交的光路中的第二检测器处检测。

    Analyte Concentration Measurement Device
    9.
    发明申请
    Analyte Concentration Measurement Device 审中-公开
    分析物浓度测定装置

    公开(公告)号：US20090018416A1

    公开(公告)日：2009-01-15

    申请号：US11777940

    申请日：2007-07-13

    申请人： Stephen D. Walker ,  Devon J. Dallmann ,  Charles W. Henry ,  Peter E. Nelson ,  R. Dale Zellers ,  John E. Repine

    发明人： Stephen D. Walker ,  Devon J. Dallmann ,  Charles W. Henry ,  Peter E. Nelson ,  R. Dale Zellers ,  John E. Repine

    IPC分类号： A61B5/00

    CPC分类号： G01N21/314 ,  A61B5/14532 ,  G01N21/35

    摘要： A method for measuring concentration of an analyte in body fluid comprises acquiring a body fluid sample, emitting light into the body fluid sample, and detecting emitted light intensity on a plurality of optical paths through the body fluid sample. A plurality of optical filters are arranged in respective optical paths of the optical path plurality comprising at least a first optical filter with light absorption by an analyte and water and a second optical filter with light absorption to water alone. Light intensity passed through the first optical filter and passed through the second optical filter is measured and analyte concentration is determined based on a ratio of intensities detected at a detector in an optical path intersected by the first optical filter and detected at a detector in an optical path intersected by the second optical filter.

    摘要翻译： 用于测量体液中分析物浓度的方法包括获取体液样品，将光发射到体液样品中，以及检测通过体液样品的多条光路上的发射光强度。 多个光学滤光器被布置在包括至少一个具有被分析物和水的光吸收的第一滤光器的光路的多个光路中，以及仅对水单独吸收光的第二滤光器。 测量通过第一滤光器并通过第二滤光器的光强度，并且基于在由第一滤光器相交的光路中的检测器处检测到的强度的比率确定分析物浓度，并在光学检测器中检测 路径与第二光学滤波器相交。

    VCSEL Tissue Spectrometer
    10.
    发明申请
    VCSEL Tissue Spectrometer 审中-公开
    VCSEL组织光谱仪

    公开(公告)号：US20080004513A1

    公开(公告)日：2008-01-03

    申请号：US11428217

    申请日：2006-06-30

    申请人： Stephen D. Walker ,  Peter E. Nelson ,  R. Dale Zellers ,  Charles W. Henry ,  John E. Repine

    发明人： Stephen D. Walker ,  Peter E. Nelson ,  R. Dale Zellers ,  Charles W. Henry ,  John E. Repine

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14532 ,  A61B5/1455 ,  A61B5/412 ,  A61B2562/0233 ,  A61B2562/043

    摘要： In a tissue sensor, a plurality of emitters are configured to emit narrowband light into biological tissue at a plurality of selected wavelengths including one or more wavelengths indicative of a profile for one or more selected analytes and a reference wavelength at which absorbance for the selected analyte is negligible. The sensor further comprises a photo detector configured to detect light at wavelengths that emerge from the biological tissue.

    摘要翻译： 在组织传感器中，多个发射器被配置为以多个选定的波长将窄带光发射到生物组织中，所述多个选定波长包括一个或多个波长，其指示一个或多个所选分析物的分布，以及所选分析物的吸光度 是微不足道的 传感器还包括被配置为检测从生物组织出现的波长处的光的光检测器。