Minimal surface area contact device for holding plaque to blood vessel wall

    公开(公告)号:US10188533B2

    公开(公告)日:2019-01-29

    申请号:US12790819

    申请日:2010-05-29

    摘要: A tack device for holding plaque against blood vessel walls in treating atherosclerotic occlusive disease is formed as a thin, annular band of durable, flexible material having a plurality of focal elevating elements on its outer annular periphery for holding loose plaque under a spring or other expansion force against a blood vessel wall. The focal elevating elements are designed to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the intraluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.

    DEVICE AND METHOD FOR TACKING PLAQUE TO A BLOOD VESSEL WALL
    2.
    发明申请
    DEVICE AND METHOD FOR TACKING PLAQUE TO A BLOOD VESSEL WALL 有权
    用于将血液束压到血管壁的装置和方法

    公开(公告)号:US20120083872A1

    公开(公告)日:2012-04-05

    申请号:US13246776

    申请日:2011-09-27

    IPC分类号: A61F2/82

    摘要: A tack device for holding plaque against blood vessel walls in treating atherosclerotic occlusive disease can be formed as a thin, annular band of durable, flexible material. The tack device may also have a plurality of barbs or anchoring points on its outer annular periphery. The annular band can have a length in the axial direction of the blood vessel walls that is about equal to or less than its diameter as installed in the blood vessel. A preferred method is to perform angioplasty with a drug eluting balloon as a first step, and if there is any dissection to the blood vessel caused by the balloon angioplasty, one or more tack devices may be installed to tack down the dissected area of the blood vessel surface, in order to avoid the need to install a stent and thereby maintain a ‘stent-free’ environment.

    摘要翻译: 用于在治疗动脉粥样硬化闭塞性疾病中用于保持血管壁的斑块的粘合装置可以形成为耐用的柔性材料的薄的环形带。 定位装置还可以在其外环形周边上具有多个倒钩或锚定点。 环形带可以在血管壁的轴向上具有大约等于或小于安装在血管中的直径的长度。 优选的方法是用药物洗脱球囊进行血管成形术作为第一步骤,并且如果由球囊血管成形术引起的对血管的任何解剖,可以安装一个或多个定位装置以粘住血液的解剖区域 容器表面,以避免需要安装支架,从而维持“无支架”环境。

    Device and method for tacking plaque to a blood vessel wall
    4.
    发明授权
    Device and method for tacking plaque to a blood vessel wall 有权
    将斑块固定在血管壁上的装置和方法

    公开(公告)号:US08128677B2

    公开(公告)日:2012-03-06

    申请号:US12483193

    申请日:2009-06-11

    IPC分类号: A61F2/06

    摘要: A tack device for holding plaque against blood vessel walls in treating atherosclerotic occlusive disease is formed as a thin, annular band of durable, flexible material having a plurality of barbs or anchoring points on its outer annular periphery. The annular band has a length in the axial direction of the blood vessel walls that is about equal to or less than its diameter as installed in the blood vessel. In a preferred embodiment, the tack device is formed as a compressible metallic mesh band having outer barbs on outer sides of the mesh structure. Another embodiment may have a plurality of compressible mesh bands may be formed spaced apart coaxially from each other and connected by longitudinally extending bridge members. A preferred method is to perform angioplasty with a drug eluting balloon as a first step, and if there is any dissection to the blood vessel caused by the balloon angioplasty, one or more tack devices may be installed to tack down the dissected area of the blood vessel surface, in order to avoid the need to install a stent and thereby maintain a ‘stent-free’ environment.

    摘要翻译: 形成用于在治疗动脉粥样硬化性闭塞性疾病中用于保持针对血管壁的斑块的粘合装置作为耐用的柔性材料的薄的环形带,其在其外环形周边上具有多个倒钩或锚定点。 环形带在血管壁的轴向方向上的长度大约等于或小于安装在血管中的直径。 在一个优选实施例中,定位装置形成为在网状结构的外侧上具有外倒钩的可压缩金属网带。 另一实施例可以具有多个可压缩的网带可以彼此同轴地形成并且通​​过纵向延伸的桥构件连接。 优选的方法是用药物洗脱球囊进行血管成形术作为第一步骤,并且如果由球囊血管成形术引起的对血管的任何解剖,可以安装一个或多个定位装置以粘住血液的解剖区域 容器表面,以避免需要安装支架,从而维持“无支架”环境。

    Device and method for opening blood vessels by pre-angioplasty serration and dilatation of atherosclerotic plaque
    6.
    发明授权
    Device and method for opening blood vessels by pre-angioplasty serration and dilatation of atherosclerotic plaque 有权
    通过前血管成形术锯齿开放血管和动脉粥样硬化斑块扩张的装置和方法

    公开(公告)号:US08323243B2

    公开(公告)日:2012-12-04

    申请号:US12408035

    申请日:2009-03-20

    IPC分类号: A61M29/00 A61M31/00 A61M37/00

    摘要: An intravascular device can comprise a carrier and an expansion apparatus. The device can be used for intravascular treatment of atherosclerotic plaque. The carrier can be reversibly expandable and collapsible within a vessel and can have ribbon strips extending between opposite ends in a longitudinal direction of the carrier. The ribbon strips can each be formed with a plurality of elongated protrusions thereon. The expansion apparatus can be used to actuate the ribbon strips each with the plurality elongated protrusions to pierce a luminal surface of the plaque with lines or patterns of microperforations which act as serrations for forming cleavage lines or planes in the plaque.

    摘要翻译: 血管内装置可以包括载体和膨胀装置。 该装置可用于动脉粥样硬化斑块的血管内治疗。 载体可以在容器内可逆地膨胀和折叠,并且可以具有在载体的纵向方向上在相对端之间延伸的带条。 带条可以在其上形成有多个细长突起。 膨胀装置可以用于致动具有多个细长突起的带状带,以利用用于在斑块中形成切割线或平面的锯齿线或微孔的线或图案刺穿斑块的管腔表面。

    Intravascular device
    8.
    发明授权
    Intravascular device 有权
    血管内装置

    公开(公告)号:US09480826B2

    公开(公告)日:2016-11-01

    申请号:US12562511

    申请日:2009-09-18

    摘要: A device and method for intravascular treatment of atherosclerotic plaque prior to balloon angioplasty. An intravascular device can comprise a carrier configured for expansion within a vessel. The carrier can have a s plurality of ribbon strips extending longitudinally between a first end and a second end. An open slot can be positioned between adjacent ribbon strips. A plurality of spikes can be positioned on each of the ribbon strips. The spikes can act as serrations for forming cleavage lines or planes in plaque in the vessel. The spikes may also be used to transport medication into the plaque. The plaque preparation treatment can enables subsequent angioplasty to be performed at low balloon pressures, can reduces dissections, and avoids injury to the arterial wall.

    摘要翻译: 球囊血管成形术前血管内治疗动脉粥样硬化斑块的装置和方法。 血管内装置可以包括构造用于在血管内扩张的载体。 载体可以具有在第一端和第二端之间纵向延伸的多条带条。 一个开放的槽可以位于相邻的带状条之间。 多个尖钉可以位于每个带条上。 尖峰可以作为在血管中的斑块中形成切割线或平面的锯齿。 尖峰也可用于将药物输送到斑块中。 斑块制备处理可使随后的血管成形术能够在低气囊压力下进行,可以减少解剖,并避免对动脉壁的损伤。

    STENT DEVICE HAVING FOCAL ELEVATING ELEMENTS FOR MINIMAL SURFACE AREA CONTACT WITH LUMEN WALLS
    9.
    发明申请
    STENT DEVICE HAVING FOCAL ELEVATING ELEMENTS FOR MINIMAL SURFACE AREA CONTACT WITH LUMEN WALLS 审中-公开
    具有最小表面积的焦点元素的连接装置与LUMEN WALLS接触

    公开(公告)号:US20110230954A1

    公开(公告)日:2011-09-22

    申请号:US13118388

    申请日:2011-05-28

    IPC分类号: A61F2/82

    摘要: An improved stent device has a body structure in tubular form sized to an organ lumen in which it is to be used and made of a wire mesh or cage structure of interwoven or interdigitated strut sections, and a plurality of focal elevating elements of relatively small point-like size or vector-like edge in an array over outer surfaces of the wire mesh or strut sections of the stent body structure. The focal elevating elements elevate the wire mesh or strut sections away from and minimize surface area contact with the organ lumen walls. They also reduce contact pressure in regions neighboring the focal elevating elements in order to minimize trauma due to contact or movement against the organ lumen walls. A preferred use for the stent device is in a blood vessel lumen, particularly to retain plaque dissection after balloon angioplasty.

    摘要翻译: 改进的支架装置具有管状形状的体结构,其尺寸适于器官内腔,其中其将被使用并由具有相互交叉或交叉的支柱部分的丝网或笼结构构成,并且具有相对小点的多个焦点升高元件 在支架主体结构的丝网或支柱部分的外表面上的阵列中的类似尺寸或矢状样边缘。 焦点升高元件将丝网或支柱部分提升远离并使与器官管腔壁的表面区域接触最小化。 它们还降低与焦点升高元件相邻的区域中的接触压力,以便最小化由于与器官腔壁的接触或运动引起的创伤。 用于支架装置的优选用途是在血管内腔中,特别是在球囊血管成形术后保留斑块解剖。