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公开(公告)号：US06752964B1
公开(公告)日：2004-06-22
申请号：US09338339
申请日：1999-06-22
IPC分类号： G01N2700
CPC分类号： G01N27/126 , G01N33/0031
摘要： This invention relates to a novel class of vapor sensors with tunable properties. More particularly, this invention relates to vapor sensors modified by the addition of a compatible small molecule of low volatility, i.e., a plasticizer. In certain aspects, the invention relates to a sensor for detecting an analyte in a fluid comprising: an organic polymer; a plasticizer combined with the organic polymer; and detector operatively associated with the organic polymer.
摘要翻译： 本发明涉及具有可调谐性质的新型蒸气传感器。 更具体地说，本发明涉及通过加入低挥发性的相容小分子即增塑剂来改进的蒸气传感器。 在某些方面，本发明涉及一种用于检测流体中分析物的传感器，包括：有机聚合物; 增塑剂与有机聚合物结合; 和可操作地与有机聚合物相关的检测器。
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2.发明授权公开(公告)号：US06610367B2
公开(公告)日：2003-08-26
申请号：US09910242
申请日：2001-07-20
IPC分类号： B05D102
CPC分类号： G01N33/0031 , G01N15/0826 , G01N27/126 , G01N29/022 , G01N29/449 , G01N2291/0217 , G01N2291/0256 , G01N2291/02863 , G01N2291/0423 , G01N2291/0426
摘要： Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient.
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3.发明授权公开(公告)号：US06387329B1
公开(公告)日：2002-05-14
申请号：US09442074
申请日：1999-11-16
IPC分类号： G01N2700
CPC分类号： G01N33/0031 , G01N15/0826 , G01N27/126 , G01N29/022 , G01N29/449 , G01N2291/0217 , G01N2291/0256 , G01N2291/02863 , G01N2291/0423 , G01N2291/0426
摘要： Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient.
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4.发明授权公开(公告)号：US06759010B2
公开(公告)日：2004-07-06
申请号：US09910243
申请日：2001-07-20
IPC分类号： G01N2702
CPC分类号： G01N33/0031 , G01N15/0826 , G01N27/126 , G01N29/022 , G01N29/449 , G01N2291/0217 , G01N2291/0256 , G01N2291/02863 , G01N2291/0423 , G01N2291/0426
摘要： Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient.
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5.发明授权公开(公告)号：US07144553B2
公开(公告)日：2006-12-05
申请号：US10651917
申请日：2003-08-29
IPC分类号： G01N27/02
CPC分类号： G01N33/0031 , G01N15/0826 , G01N27/126 , G01N29/022 , G01N29/449 , G01N2291/0217 , G01N2291/0256 , G01N2291/02863 , G01N2291/0423 , G01N2291/0426
摘要： Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient.
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公开(公告)号：US06890715B1
公开(公告)日：2005-05-10
申请号：US09642115
申请日：2000-08-18
CPC分类号： G01N27/126 , G01N33/0031
摘要： The present invention provides a class of sensors prepared from at least a first material having a positive temperature coefficient of resistance and a second non-conductive or insulating material compositionally different than the first material that show an increase sensitivity detection limit for polar and non-polar analytes. The sensors have applications in the detection of analytes in the environment, associated with diseases and microorganisms.
摘要翻译： 本发明提供了一种由至少具有正电阻温度系数的第一材料制成的传感器，以及与第一材料成分不同的第二非导电或绝缘材料，其显示极性和非极性的灵敏度检测极限的增加 分析物。 这些传感器可用于检测与疾病和微生物相关的环境中的分析物。
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公开(公告)号：US07550310B2
公开(公告)日：2009-06-23
申请号：US11439136
申请日：2006-05-24
申请人： Rodney M. Goodman , Nathan S. Lewis , Robert H. Grubbs , Jeffery Dickson , Vincent F. Koosh , Richard S. Payne
发明人： Rodney M. Goodman , Nathan S. Lewis , Robert H. Grubbs , Jeffery Dickson , Vincent F. Koosh , Richard S. Payne
IPC分类号： H01L21/00 , H01L21/4763
CPC分类号： G01N27/128 , G01N27/126 , G01N27/221 , G01N33/0031
摘要： Techniques are used to detect and identify analytes. Techniques are used to fabricate and manufacture sensors to detect analytes. An analyte (810) is sensed by sensors (820) that output electrical signals in response to the analyte. The electrical signals may be preprocessed (830) by filtering and amplification. In one embodiment, a plurality of sensors are formed on a single integrated circuit. The sensors may have diverse compositions.
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8.发明授权Compositionally different polymer-based sensor elements and method for preparing same 失效组成不同的基于聚合物的传感器元件及其制备方法公开(公告)号：US06290911B1
公开(公告)日：2001-09-18
申请号：US09106791
申请日：1998-06-29
IPC分类号： G01N2702
CPC分类号： G01N27/126 , B01J19/0046 , B01J2219/00351 , B01J2219/00524 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00637 , B01J2219/00659 , B01J2219/00707 , B01J2219/00722 , C40B40/14 , C40B60/14 , G01N21/77 , G01N33/0031 , G01N2021/773 , Y10T436/2575
摘要： The present invention provides a combinatorial approach for preparing arrays of chemically sensitive polymer-based sensors which are capable of detecting the presence of a chemical analyte in a fluid in contact therewith. The described methods and devices comprise combining varying ratios of at least first and second organic materials which, when combined, form a polymer or polymer blend that is capable of absorbing a chemical analyte, thereby providing a detectable response. The detectable response of the sensors prepared by this method is not linearly related to the mole fraction of at least one of the polymer-based components of the sensors, thereby making arrays of these sensors useful for a variety of sensing tasks.
摘要翻译： 本发明提供了一种用于制备化学敏感聚合物基传感器阵列的组合方法，其能够检测与其接触的流体中化学分析物的存在。 所描述的方法和装置包括组合至少第一和第二有机材料的变化比例，其在组合时形成能够吸收化学分析物的聚合物或聚合物共混物，由此提供可检测的响应。 通过该方法制备的传感器的可检测响应与传感器的至少一种基于聚合物的组分的摩尔分数没有线性关系，从而使得这些传感器的阵列可用于各种感测任务。
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公开(公告)号：US06495892B2
公开(公告)日：2002-12-17
申请号：US09276988
申请日：1999-03-26
申请人： Rodney M. Goodman , Nathan S. Lewis , Robert H. Grubbs , Jeffery Dickson , Vincent Koosh , Richard S. Payne
发明人： Rodney M. Goodman , Nathan S. Lewis , Robert H. Grubbs , Jeffery Dickson , Vincent Koosh , Richard S. Payne
IPC分类号： H01L2714
CPC分类号： G01N33/0031 , H01L2924/0002 , H01L2924/00
摘要： Techniques are used to detect and identify analytes. Techniques are used to fabricate and manufacture sensors to detect analytes. An analyte (810) is sensed by sensors (820) that output electrical signals in response to the analyte. The electrical signals may be preprocessed (830) by filtering and amplification. In one embodiment, a plurality of sensors are formed on a single integrated circuit. The sensors may have diverse compositions.
摘要翻译： 技术用于检测和识别分析物。 技术用于制造和制造传感器以检测分析物。 通过传感器（820）感测分析物（810），其响应于分析物输出电信号。 电信号可以通过滤波和放大进行预处理（830）。 在一个实施例中，多个传感器形成在单个集成电路上。 传感器可以具有不同的组成。
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10.发明授权Compositionally different polymer-based sensor elements and methods for preparing same 失效组分不同的基于聚合物的传感器元件及其制备方法公开(公告)号：US07175885B2
公开(公告)日：2007-02-13
申请号：US09770089
申请日：2001-01-24
IPC分类号： B05D1/02
CPC分类号： G01N27/126 , B01J19/0046 , B01J2219/00351 , B01J2219/00524 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00637 , B01J2219/00659 , B01J2219/00707 , B01J2219/00722 , C40B40/14 , C40B60/14 , G01N21/77 , G01N33/0031 , G01N2021/773 , Y10T436/2575
摘要： The present invention provides a combinatorial approach for preparing arrays of chemically sensitive polymer-based sensors which are capable of detecting the presence of a chemical analyte in a fluid in contact therewith. The described methods and devices comprise combining varying ratios of at least first and second organic materials which, when combined, form a polymer or polymer blend that is capable of absorbing a chemical analyte, thereby providing a detectable response. The detectable response of the sensors prepared by this method is not linearly related to the mole fraction of at least one of the polymer-based components of the sensors, thereby making arrays of these sensors useful for a variety of sensing tasks.
摘要翻译： 本发明提供了一种用于制备化学敏感聚合物基传感器阵列的组合方法，其能够检测与其接触的流体中化学分析物的存在。 所描述的方法和装置包括组合至少第一和第二有机材料的变化比例，其在组合时形成能够吸收化学分析物的聚合物或聚合物共混物，由此提供可检测的响应。 通过该方法制备的传感器的可检测响应与传感器的至少一种基于聚合物的组分的摩尔分数没有线性关系，从而使得这些传感器的阵列可用于各种感测任务。
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