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公开(公告)号：US20060128780A1
公开(公告)日：2006-06-15
申请号：US11346524
申请日：2006-02-02
IPC分类号： A61K31/407 , C07D487/02
CPC分类号： C07D487/04 , C07D209/94
摘要： The present invention is directed to cyclic substituted fused pyrrolocarbazoles and isoindolones. The invention also is directed to methods for making and using the cyclic substituted fused pyrrolocarbazoles and isoindolones.
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公开(公告)号：US07074793B2
公开(公告)日：2006-07-11
申请号：US10755505
申请日：2004-01-12
IPC分类号： A61K31/501 , C07D403/14
CPC分类号： C07D487/04 , C07D209/94
摘要： The present invention is directed to cyclic substituted fused pyrrolocarbazoles and isoindolones. The invention also is directed to methods for making and using the cyclic substituted fused pyrrolocarbazoles and isoindolones.
摘要翻译： 本发明涉及环状取代的稠合吡咯并咔唑和异吲哚酮。 本发明还涉及制备和使用环状取代的稠合吡咯并咔唑和异吲哚酮的方法。
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公开(公告)号：US06841567B1
公开(公告)日：2005-01-11
申请号：US09500849
申请日：2000-02-10
IPC分类号： A61K20060101 , A61K31/40 , A61K31/407 , A61K31/4745 , A61K31/5025 , A61P20060101 , A61P9/10 , A61P11/00 , A61P13/08 , A61P15/00 , A61P17/02 , A61P17/06 , A61P19/02 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/18 , A61P35/00 , A61P37/06 , A61P43/00 , C07D20060101 , C07D487/04 , C07D519/00
CPC分类号： C07D487/04 , C07D209/94
摘要： The present invention is directed to cyclic substituted fused pyrrolocarbazoles and isoindolones. The invention also is directed to methods for making and using the cyclic substituted fused pyrrolocarbazoles and isoindolones.
摘要翻译： 本发明涉及环状取代的稠合吡咯并咔唑和异吲哚酮。 本发明还涉及制备和使用环状取代的稠合吡咯并咔唑和异吲哚酮的方法。
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公开(公告)号：US07288650B2
公开(公告)日：2007-10-30
申请号：US11346524
申请日：2006-02-02
IPC分类号： C07D487/02 , C07D237/00 , A61K31/407
CPC分类号： C07D487/04 , C07D209/94
摘要： The present invention is directed to cyclic substituted fused pyrrolocarbazoles and isoindolones. The invention also is directed to methods for making and using the cyclic substituted fused pyrrolocarbazoles and isoindolones.
摘要翻译： 本发明涉及环状取代的稠合吡咯并咔唑和异吲哚酮。 本发明还涉及制备和使用环状取代的稠合吡咯并咔唑和异吲哚酮的方法。
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公开(公告)号：US06359130B1
公开(公告)日：2002-03-19
申请号：US09572160
申请日：2000-05-17
申请人： Jasbir Singh , Robert L. Hudkins , John P. Mallamo , Theodore L. Underiner , Rabindranath Tripathy
发明人： Jasbir Singh , Robert L. Hudkins , John P. Mallamo , Theodore L. Underiner , Rabindranath Tripathy
IPC分类号： C07D49822
CPC分类号： C07D498/22
摘要： The present invention is directed to novel fused aryl and heteroaryl bridged indenopyrrolocarbazoles which are useful, inter alia, as therapeutic agents. The invention is also directed to methods for making and using the bridged indenopyrrolocarbazoles.
摘要翻译： 本发明涉及新的稠合芳基和杂芳基桥连茚并吡唑并唑，其特别可用作治疗剂。 本发明还涉及制备和使用桥连茚并吡唑并唑的方法。
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公开(公告)号：US06455525B1
公开(公告)日：2002-09-24
申请号：US09702191
申请日：2000-10-31
IPC分类号： A61K3153
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04
摘要： The present invention is directed to novel heterocyclic substituted pyrazolones, including pharmaceutical compositions, diagnostic kits, assay standards or reagents containing the same, and methods of using the same as therapeutics. The invention is also directed to intermediates and processes for making these novel compounds.
摘要翻译： 本发明涉及新颖的杂环取代的吡唑啉酮，包括药物组合物，诊断试剂盒，测定标准品或含有它们的试剂，以及使用它们作为治疗剂的方法。 本发明还涉及制备这些新化合物的中间体和方法。
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公开(公告)号：US6127401A
公开(公告)日：2000-10-03
申请号：US325140
申请日：1999-06-03
申请人： Jasbir Singh , Robert L. Hudkins , John P. Mallamo , Theodore L. Underiner , Rabindranath Tripathy
发明人： Jasbir Singh , Robert L. Hudkins , John P. Mallamo , Theodore L. Underiner , Rabindranath Tripathy
IPC分类号： A61K31/55 , A61K31/553 , A61P9/00 , A61P9/10 , A61P11/00 , A61P13/08 , A61P15/00 , A61P17/02 , A61P17/06 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07D498/22
CPC分类号： C07D498/22
摘要： The present invention is directed to novel fused aryl and heteroaryl bridged indenopyrrolocarbazoles which are useful, inter alia, as therapeutic agents. The invention is also directed to methods for making and using the bridged indenopyrrolocarbazoles.
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公开(公告)号：US06831075B2
公开(公告)日：2004-12-14
申请号：US10225670
申请日：2002-08-22
IPC分类号： A61K3133
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04
摘要： The present invention is directed to novel heterocyclic substituted pyrazolones, including pharmaceutical compositions, diagnostic kits, assay standards or reagents containing the same, and methods of using the same as therapeutics. The invention is also directed to intermediates and processes for making these novel compounds.
摘要翻译： 本发明涉及新颖的杂环取代的吡唑啉酮，包括药物组合物，诊断试剂盒，测定标准品或含有它们的试剂，以及使用它们作为治疗剂的方法。 本发明还涉及制备这些新化合物的中间体和方法。
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公开(公告)号：US12102223B2
公开(公告)日：2024-10-01
申请号：US17609850
申请日：2020-05-08
申请人： Jasbir Singh
发明人： Jasbir Singh
IPC分类号： A47B46/00
CPC分类号： A47B46/00
摘要： A cabinet and an access mechanism for the cabinet is disclosed. The cabinet may comprise of a door to access the interior. The door and the adjacent coplanar may be mounted movable jointed combination of first type of frames and second type of frames with telescopic slides and/or guide roller assemblies disposed between to impart the freedom of motion in the desired direction upon a suitable actuation. The first type of frames have been provided with an ability to pivot. The pivots being vertical axillar elements. The arrangement of the two types of frames with pivoted vertical axis provides a plurality of assemblies or shelves mounted on respective door and coplanar portion. The shelves are displaced angularly and laterally owing to the actuating mechanism of the door. The assemblies or shelves are interconnected using coupling elements, horizontal arms and a multiplicity of pivot points arranged at pre-determined distances.
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10.发明授权Biaryl substituted heterocycle inhibitors of LTA4H for treating inflammation 失效用于治疗炎症的LTA4H的二芳基取代的杂环抑制剂公开(公告)号：US08598359B2
公开(公告)日：2013-12-03
申请号：US12136874
申请日：2008-06-11
申请人： Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
发明人： Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
IPC分类号： C07D211/20 , A61K31/445
CPC分类号： C07D403/12 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/26 , C07D207/263 , C07D207/46 , C07D211/22 , C07D241/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D413/06 , C07D413/12 , C07D417/12
摘要： The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ: An example is
摘要翻译： 本发明涉及可用于治疗和预防和预防炎性疾病和病症的LTA4H（白三烯A4水解酶）的联芳基取代的杂环抑制剂的化学属。 化合物具有通式Psi：一个例子
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