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1.发明申请Methods and systems for in situ tissue marking and orientation stabilization 审中-公开用于原位组织标记和取向稳定的方法和系统公开(公告)号：US20070198010A1
公开(公告)日：2007-08-23
申请号：US11737382
申请日：2007-04-19
申请人： Roberta LEE , James Vetter , Ary Chernomorsky
发明人： Roberta LEE , James Vetter , Ary Chernomorsky
CPC分类号： A61B10/0266 , A61B18/148 , A61B2018/00333 , A61B2018/00601 , A61B2018/141 , A61B2018/1475 , A61B2090/3908 , A61B2090/3937 , A61B2090/395
摘要： A method of marking an orientation of a cut specimen of tissue prior to excision thereof from a body includes steps of disposing a tissue-marking probe in the body adjacent the cut specimen, the tissue-marking probe including a tissue-marking tool configured to selectively mark the cut specimen. A surface of the cut specimen is then marked with the tissue-marking tool such that the orientation of the cut specimen within the body is discernable after the cut specimen is excised from the body. The tissue-marking tool may be configured to selectively bow out of and back into a window defined near a distal tip of the probe and the marking step may include a step of selectively bowing the tissue-marking tool out of the window and following the surface of the cut specimen while rotating the probe. The tissue-marking tool may include an RF cutting tool and the marking step may include a step of coagulating or cauterizing a selected portion of the surface of the cut specimen with the RF cutting tool. Alternatively, the marking step may include a step of delivering dye onto selected portions of the surface of the cut specimen.
摘要翻译： 在从身体切除之前标记组织切割样本的取向的方法包括以下步骤：将组织标记探针设置在与切割的样本相邻的身体中，组织标记探针包括组织标记工具，其被配置为选择性地 标记切割标本。 然后用组织标记工具标记切割的样品的表面，使得在切割的样品从身体切除之后，切割的样品在体内的取向是可辨别的。 组织标记工具可以被配置为选择性地弯曲到限定在探针的远侧末端附近的窗口中，并且标记步骤可以包括将组织标记工具选择性地弯曲出窗户并且跟随表面的步骤 同时旋转探头。 组织标记工具可以包括RF切割工具，并且标记步骤可以包括用RF切割工具凝固或烧灼切割样品表面的选定部分的步骤。 或者，标记步骤可以包括将染料递送到切割样品的表面的选定部分上的步骤。
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2.发明申请公开(公告)号：US20050027291A1
公开(公告)日：2005-02-03
申请号：US10871790
申请日：2004-06-17
申请人： Roberta Lee , James Vetter , Ary Chernomorsky
发明人： Roberta Lee , James Vetter , Ary Chernomorsky
CPC分类号： A61B10/0266 , A61B18/148 , A61B2018/00333 , A61B2018/00601 , A61B2018/141 , A61B2018/1475 , A61B2090/3908 , A61B2090/3937 , A61B2090/395
摘要： A method of marking an orientation of a cut specimen of tissue prior to excision thereof from a body includes steps of disposing a tissue-marking probe in the body adjacent the cut specimen, the tissue-marking probe including a tissue-marking tool configured to selectively mark the cut specimen. A surface of the cut specimen is then marked with the tissue-marking tool such that the orientation of the cut specimen within the body is discernable after the cut specimen is excised from the body. The tissue-marking tool may be configured to selectively bow out of and back into a window defined near a distal tip of the probe and the marking step may include a step of selectively bowing the tissue-marking tool out of the window and following the surface of the cut specimen while rotating the probe. The tissue-marking tool may include an RF cutting tool and the marking step may include a step of coagulating or cauterizing a selected portion of the surface of the cut specimen with the RF cutting tool. Alternatively, the marking step may include a step of delivering dye onto selected portions of the surface of the cut specimen.
摘要翻译： 在从身体切除之前标记组织切割样本的取向的方法包括以下步骤：将组织标记探针设置在与切割的样本相邻的身体中，组织标记探针包括组织标记工具，其被配置为选择性地 标记切割标本。 然后用组织标记工具标记切割的样品的表面，使得在切割的样品从身体切除之后，切割的样品在体内的取向是可辨别的。 组织标记工具可以被配置为选择性地弯曲到限定在探针的远侧末端附近的窗口中，并且标记步骤可以包括将组织标记工具选择性地弯曲出窗户并且跟随表面的步骤 同时旋转探头。 组织标记工具可以包括RF切割工具，并且标记步骤可以包括用RF切割工具凝固或烧灼切割样品表面的选定部分的步骤。 或者，标记步骤可以包括将染料递送到切割样品的表面的选定部分上的步骤。
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公开(公告)号：US20050182339A1
公开(公告)日：2005-08-18
申请号：US11045006
申请日：2005-01-26
申请人： Roberta Lee , James Vetter , Ary Chernomorsky
发明人： Roberta Lee , James Vetter , Ary Chernomorsky
IPC分类号： A61B10/02 , A61B8/12 , A61B10/00 , A61B10/04 , A61B17/22 , A61B18/12 , A61B18/14 , A61B19/00 , A61B17/32
CPC分类号： A61B10/0266 , A61B10/0041 , A61B10/02 , A61B10/04 , A61B17/320725 , A61B18/1482 , A61B2018/00011 , A61B2018/00333 , A61B2018/1407 , A61B2018/1475 , A61B2090/3782 , A61B2090/3784 , A61B2218/002
摘要： An excisional biopsy system includes a tubular member that has a proximal end and a distal end in which one or more windows are defined. A first removable probe has a proximal portion that includes a cutting tool extender and a distal portion that includes a cutting tool. The first removable probe may be configured to fit at least partially within the tubular member to enable the cutting tool to selectively bow out of and to retract within one of the windows when the cutting tool extender is activated. A second removable probe has a proximal section that includes a tissue collection device extender and a distal section that includes a tissue collection device. The second removable probe may also be configured to fit at least partially within the tubular member to enable the tissue collection device to extend out of and to retract within one of the windows when the tissue collection device extender is activated. A third removable probe may also be provided. The third removable probe may also be configured to fit at least partially within the tubular member and may include an imaging device, such as an ultrasound transducer, mounted therein. By selectively activating the cutting tool and the tissue collection device while rotating the excisional device, a tissue specimen may be cut from the surrounding tissue and collected for later analysis.
摘要翻译： 切除活检系统包括管状构件，其具有限定一个或多个窗口的近端和远端。 第一可移除探针具有近端部分，其包括切削刀具延伸器和包括切削工具的远端部分。 第一可移除探针可以被配置为至少部分地配合在管状构件内，以使得当切割工具延伸器被激活时，切割工具能够选择性地弯曲在一个窗口内并缩回。 第二可移除探针具有近端部分，其包括组织收集装置延伸器和包括组织收集装置的远端部分。 第二可移除探针也可以被配置为至少部分地配合在管状构件内，以使组织收集装置在组织收集装置延伸器被启动时延伸出窗口内的一个窗口并缩回。 还可以提供第三可移除探针。 第三可移除探针也可以被配置为至少部分地配合在管状构件内，并且可以包括安装在其中的成像装置，例如超声换能器。 通过在旋转切除装置的同时选择性地激活切割工具和组织收集装置，可以从周围组织切割组织标本并收集用于随后的分析。
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公开(公告)号：US20050020899A1
公开(公告)日：2005-01-27
申请号：US10627960
申请日：2003-07-25
CPC分类号： A61M31/005 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3987 , A61K49/04 , A61L31/146 , A61L31/18
摘要： An embodiment of a post-biopsy cavity treatment implant includes a first portion including a first porous matrix defining a first controlled pore architecture or crosslinking density, and a second portion coupled to the first portion. The second portion includes a second porous matrix that defines a second controlled pore architecture or a second crosslinking density that is different from the first controlled pore architecture or the first crosslinking density, causing the second portion to swell in a different manner than the first portion when the implant is placed in an aqueous environment.
摘要翻译： 活检后腔腔治疗植入物的实施方案包括第一部分，其包括限定第一受控孔结构或交联密度的第一多孔基质，以及耦合到第一部分的第二部分。 第二部分包括限定第二受控孔结构的第二多孔基质或不同于第一受控孔结构或第一交联密度的第二交联密度，导致第二部分以与第一部分不同的方式膨胀， 将植入物置于含水环境中。
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公开(公告)号：US20070203513A1
公开(公告)日：2007-08-30
申请号：US11742391
申请日：2007-04-30
IPC分类号： A61B17/32
CPC分类号： A61B10/0266 , A61B2017/00287 , A61B2017/008 , A61B2018/1407
摘要： A method of cutting breast tissue for removal may include a step of providing a tissue cutting device having an elongate cutting element, the cutting element being movable between a bowed position and a retracted position, the cutting element having a radially outer side and a radially inner side. The tissue cutting device may be introduced into a breast and the elongate cutting element may be moved to the bowed position. A power source may be coupled to the elongate cutting element; and the cutting element may be rotated after the moving step so that the cutting element cuts the breast tissue. The radially outer side of the cutting element may have a larger surface area for transmitting energy to cut the tissue than the radially inner side.
摘要翻译： 切割乳房组织以便去除的方法可以包括提供具有细长切割元件的组织切割装置的步骤，所述切割元件可在弓形位置和缩回位置之间移动，所述切割元件具有径向外侧和径向内部 侧。 组织切割装置可以被引入到乳房中，并且细长切割元件可以移动到弓形位置。 电源可以耦合到细长切割元件; 并且切割元件可以在移动步骤之后旋转，使得切割元件切割乳房组织。 切割元件的径向外侧可以具有比径向内侧更大的用于传递切割组织的能量的表面积。
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公开(公告)号：US20070135711A1
公开(公告)日：2007-06-14
申请号：US11673510
申请日：2007-02-09
申请人： Ary Chernomorsky , Sean Daniel , James Vetter
发明人： Ary Chernomorsky , Sean Daniel , James Vetter
IPC分类号： A61B6/00
CPC分类号： A61B90/39 , A61B2090/3908 , A61B2090/3925
摘要： A method of marking a cavity in a breast for subsequent visualization may include steps of providing a device having a delivery opening, a first marker and a second marker, the first and second markers being movable through the delivery opening, the first marker being configured to be visualized by ultrasound and the second marker configured to be radiopaque, the first and second markers being free to move relative to one another; introducing the device into a breast so that the delivery opening is positioned in a cavity formed in the breast; and moving the first marker and the second marker through the delivery opening and into the cavity in the breast, the first and second markers being free to move relative to one another when delivered into the cavity so that the first and second markers may take a number of different positions relative to one another when positioned within the cavity.
摘要翻译： 一种在乳房中标记腔体以便随后可视化的方法可以包括提供具有输送开口，第一标记和第二标记的装置的步骤，第一和第二标记可移动穿过输送开口，第一标记被配置为 通过超声可视化，第二标记被配置为不透射线，第一和第二标记物可相对于彼此自由移动; 将装置引入乳房，使得输送口位于形成在乳房中的空腔中; 以及通过所述输送开口移动所述第一标记和所述第二标记并进入所述乳房中的空腔中，所述第一标记和所述第二标记在递送到所述空腔中时相对于彼此自由移动，使得所述第一标记和所述第二标记可以取数 当位于空腔内时相对于彼此的不同位置。
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公开(公告)号：US20060229650A1
公开(公告)日：2006-10-12
申请号：US11391791
申请日：2006-03-28
IPC分类号： A61B17/32
CPC分类号： A61B10/0266 , A61B2017/00287 , A61B2017/008 , A61B2018/1407
摘要： Devices and methods for cutting and collecting a specimen from a mass of tissue. The device may include an integrated cut and collect assembly. The integrated cut and collect assembly includes a cutting portion and a collection portion that includes a flexible membrane. The collection portion of the assembly is attached to the cutting portion thereof. The cutting portion is configured to cut the specimen from the mass of tissue and the collection portion is configured to collect the cut specimen and to encapsulate and isolate the cut specimen within the membrane to enable its safe retraction from the mass of tissue.
摘要翻译： 从大量组织切割和收集标本的装置和方法。 该装置可以包括集成的切割和收集组件。 集成的切割和收集组件包括切割部分和包括柔性膜的收集部分。 组件的收集部分附接到其切割部分。 切割部分被构造成从组织块切割样本，并且收集部分被配置为收集切割的样本并且将切割的样本包封并分离在膜内以使其能够从组织块的安全回缩。
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公开(公告)号：US20070208273A1
公开(公告)日：2007-09-06
申请号：US11742374
申请日：2007-04-30
IPC分类号： A61B10/02
CPC分类号： A61B10/0266 , A61B2017/00287 , A61B2017/008 , A61B2018/1407
摘要： A device for removing breast tissue may include a shaft and a cutting element mounted to the shaft. The cutting element may be movable between a bowed position and a straightened position. The cutting element may bow outward away from the shaft when in the bowed position. The cutting element may have an elongate cutting side which cuts tissue when the shaft is rotated. The cutting element may have a length that is at least 25 times larger than a width of the cutting element.
摘要翻译： 用于去除乳房组织的装置可以包括轴和安装到轴上的切割元件。 切割元件可以在弯曲位置和矫直位置之间移动。 当处于弯曲位置时，切割元件可能向外向外偏离轴。 切割元件可以具有细长的切割侧，其在轴旋转时切割组织。 切割元件可以具有比切割元件的宽度大至少25倍的长度。
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公开(公告)号：US20060224084A1
公开(公告)日：2006-10-05
申请号：US11099985
申请日：2005-04-05
CPC分类号： A61B10/0233 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/32053 , A61B90/39 , A61B2017/32004 , A61B2017/320064 , A61B2090/3908 , A61B2090/3925 , A61B2090/3933 , A61B2090/395 , A61B2090/3987
摘要： The present invention is directed to tissue removal devices and methods. A tubular element having an open distal end is advanced into tissue so that tissue enters the tubular element. The tissue which entered the tubular element is cut to separate the tissue from the surrounding tissue. The tissue is then transported proximally by the cutting element or a separate transport element.
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公开(公告)号：US20050019262A1
公开(公告)日：2005-01-27
申请号：US10688289
申请日：2003-10-16
CPC分类号： A61L31/146 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/04 , A61L31/18
摘要： A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
摘要翻译： 活检后腔治疗植入物包括不透射线元件，芯部分和壳部分。 芯部分耦合到不透射线的元件，并且包括限定第一受控孔结构的第一多孔基体。 壳部分耦合到芯部分并且包括限定与第一受控孔结构不同的第二受控孔结构的第二多孔基质。
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