摘要:
The present invention relates to compounds of Formula (I): wherein R3-R8, X, and Y are as described herein, processes for preparing the compounds, pharmaceutical compositions comprising the compounds, and use of the compounds and compositions in the prophylaxis or treatment of a GHSR receptor-related disorder. Examples of such disorders are obesity and related disorders such as diabetes type II, dyslipidemia and the metabolic syndrome Prader-Willi syndrome, cardiovascular diseases such as atherosclerotic vascular disease, angina pectoris, myocardial infarction and stroke, acromegaly and cancer, in particular breast, lung, prostate, thyroid and endocrine pituary carcinomas.
摘要:
Compounds of Formula (I): wherein X, Y, Z, and R1 are as described herein, processes for preparing the compounds, pharmaceutical compositions comprising the compounds, and use of the compounds and compositions in the prophylaxis or treatment of a 5-HT2A receptor-related disorder.
摘要:
Compounds of Formula (I): wherein R and R′ are described herein, as are processes for preparing the compounds, pharmaceutical compositions comprising the compounds, and use of the compounds and compositions in the prophylaxis or treatment of a 5-HT2A receptor-related disorder.
摘要:
A fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing red light at approximately 635 nm, and at approximately 40,000 Lux, measurable at the array. The method includes reducing the lipid content of subcutaneous adipocytes using the optical emitting device, by delivering red light at approximately 313.6 Lux at a wavelength of approximately 635 nm for between 1 and 8 minutes, resulting in a total delivery of 2.88 Joules to the subcutaneous adipocytes of the target area of the recipient.
摘要:
A fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing red light at approximately 635 nm, and at approximately 40,000 Lux, measurable at the array. The method includes reducing the lipid content of subcutaneous adipocytes using the optical emitting device, by delivering red light at approximately 313.6 Lux at a wavelength of approximately 635 nm for between 1 and 8 minutes, resulting in a total delivery of 2.88 Joules to the subcutaneous adipocytes of the target area of the recipient.
摘要:
Multi-function, adjustable seats and methods and systems for their manufacture and utilization are disclosed. Such seats are especially, although not exclusively, designed for use in commercial aircraft in response to consumer requests for enhanced comfort during long-haul flights. In addition to providing rocking motion, the seats have bottoms whose lengths are adjustable and provide stowable tables adapted not only to permit vertical adjustment, but also to tilt out of a horizontal plane and latch in an as-tilted position to function as a rest for a book, magazine, computer, or other object. Digital control technology, including a touch screen or similar device, may be employed to actuate features of the disclosed seats.
摘要:
A fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing red light at approximately 635 nm, and at approximately 40,000 Lux, measurable at the array. The method includes reducing the lipid content of subcutaneous adipocytes using the optical emitting device, by delivering red light at approximately 313.6 Lux at a wavelength of approximately 635 nm for between 1 and 8 minutes, resulting in a total delivery of 2.88 Joules to the subcutaneous adipocytes of the target area of the recipient.
摘要:
A system, apparatus, and method for managing recyclable materials are disclosed. In one embodiment, an apparatus is described, the apparatus comprising an inlet port for receiving the recyclable materials, a tube connected to the inlet port, an outlet port as part of the tube for expelling the recyclable materials, a screw blade mounted inside the tube and the inlet port along a tube longitudinal axis for moving the recyclable materials through the inlet port, the tube, and the outlet port, a motor coupled to the screw blade for rotating the screw blade, thereby moving the recyclable materials through the apparatus, and a receptacle installed onto the outlet port for receiving the recyclable materials.
摘要:
A cellulite and fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing green light at approximately 529.6 nm, and at approximately 48,860 Lux, measurable at the array.
摘要:
A cellulite and fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing green light at approximately 529.6 nm, and at approximately 48,860 Lux, measurable at the array.