Beta-carbolines as growth hormone secretagogue receptor (GHSR) antagonists
    1.
    发明申请
    Beta-carbolines as growth hormone secretagogue receptor (GHSR) antagonists 审中-公开
    β-咔啉作为生长激素促分泌素受体(GHSR)拮抗剂

    公开(公告)号:US20050288316A1

    公开(公告)日:2005-12-29

    申请号:US10995067

    申请日:2004-11-22

    CPC分类号: C07D471/20 C07D491/20

    摘要: The present invention relates to compounds of Formula (I): wherein R3-R8, X, and Y are as described herein, processes for preparing the compounds, pharmaceutical compositions comprising the compounds, and use of the compounds and compositions in the prophylaxis or treatment of a GHSR receptor-related disorder. Examples of such disorders are obesity and related disorders such as diabetes type II, dyslipidemia and the metabolic syndrome Prader-Willi syndrome, cardiovascular diseases such as atherosclerotic vascular disease, angina pectoris, myocardial infarction and stroke, acromegaly and cancer, in particular breast, lung, prostate, thyroid and endocrine pituary carcinomas.

    摘要翻译: 本发明涉及式(I)的化合物:其中R 3,R 8,X和Y如本文所述,制备化合物的方法,药物组合物 包括化合物,以及化合物和组合物在预防或治疗GHSR受体相关病症中的用途。 这种障碍的例子是肥胖症和相关疾病,例如II型糖尿病,血脂异常和代谢综合征Prader-Willi综合征,心血管疾病如动脉粥样硬化性血管疾病,心绞痛,心肌梗塞和中风,肢端肥大症和癌症,特别是乳腺,肺 ,前列腺,甲状腺和内分泌胰腺癌。

    Fat reducing device and method utilizing optical emitters
    4.
    发明授权
    Fat reducing device and method utilizing optical emitters 有权
    减脂装置和利用光发射器的方法

    公开(公告)号:US09498641B2

    公开(公告)日:2016-11-22

    申请号:US13782377

    申请日:2013-03-01

    申请人: Terry Ward

    发明人: Terry Ward

    IPC分类号: A61N5/06 A61B18/00

    摘要: A fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing red light at approximately 635 nm, and at approximately 40,000 Lux, measurable at the array. The method includes reducing the lipid content of subcutaneous adipocytes using the optical emitting device, by delivering red light at approximately 313.6 Lux at a wavelength of approximately 635 nm for between 1 and 8 minutes, resulting in a total delivery of 2.88 Joules to the subcutaneous adipocytes of the target area of the recipient.

    摘要翻译: 利用光发射器的减脂装置和方法包括:容纳多个光发射器的阵列,其定位成产生指向接收器的光输出;以及控制器,用于指示阵列的操作。 由多个LED累积产生大约635nm的红光和大约40,000Lux的光输出是可以在阵列测量的。 该方法包括使用光学发射装置降低皮下脂肪细胞的脂质含量,通过在约635nm的波长处输送约313.6Lux的红光1至8分钟,导致向皮下脂肪细胞总共递送2.88焦耳 的接收者的目标区域。

    FAT REDUCING DEVICE AND METHOD UTILIZING OPTICAL EMITTERS
    5.
    发明申请
    FAT REDUCING DEVICE AND METHOD UTILIZING OPTICAL EMITTERS 有权
    FAT减少装置和利用光学发射体的方法

    公开(公告)号:US20170042616A1

    公开(公告)日:2017-02-16

    申请号:US15337833

    申请日:2016-10-28

    申请人: Terry Ward

    发明人: Terry Ward

    IPC分类号: A61B18/18 A61B18/00

    摘要: A fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing red light at approximately 635 nm, and at approximately 40,000 Lux, measurable at the array. The method includes reducing the lipid content of subcutaneous adipocytes using the optical emitting device, by delivering red light at approximately 313.6 Lux at a wavelength of approximately 635 nm for between 1 and 8 minutes, resulting in a total delivery of 2.88 Joules to the subcutaneous adipocytes of the target area of the recipient.

    摘要翻译: 利用光发射器的减脂装置和方法包括:容纳多个光发射器的阵列,其定位成产生指向接收器的光输出;以及控制器,用于指示阵列的操作。 由多个LED累积产生大约635nm的红光和大约40,000Lux的光输出是可以在阵列测量的。 该方法包括使用光学发射装置降低皮下脂肪细胞的脂质含量,通过在约635nm的波长处输送约313.6Lux的红光1至8分钟,导致向皮下脂肪细胞总共递送2.88焦耳 的接收者的目标区域。

    Fat reducing device and method utilizing optical emitters

    公开(公告)号:US09808314B2

    公开(公告)日:2017-11-07

    申请号:US15337833

    申请日:2016-10-28

    申请人: Terry Ward

    发明人: Terry Ward

    摘要: A fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing red light at approximately 635 nm, and at approximately 40,000 Lux, measurable at the array. The method includes reducing the lipid content of subcutaneous adipocytes using the optical emitting device, by delivering red light at approximately 313.6 Lux at a wavelength of approximately 635 nm for between 1 and 8 minutes, resulting in a total delivery of 2.88 Joules to the subcutaneous adipocytes of the target area of the recipient.

    Screw compactor
    8.
    发明申请
    Screw compactor 审中-公开
    螺旋压实机

    公开(公告)号:US20140260102A1

    公开(公告)日:2014-09-18

    申请号:US13797952

    申请日:2013-03-12

    申请人: Nick Ball Terry Ward

    发明人: Nick Ball Terry Ward

    IPC分类号: B65B63/02 B30B9/30

    摘要: A system, apparatus, and method for managing recyclable materials are disclosed. In one embodiment, an apparatus is described, the apparatus comprising an inlet port for receiving the recyclable materials, a tube connected to the inlet port, an outlet port as part of the tube for expelling the recyclable materials, a screw blade mounted inside the tube and the inlet port along a tube longitudinal axis for moving the recyclable materials through the inlet port, the tube, and the outlet port, a motor coupled to the screw blade for rotating the screw blade, thereby moving the recyclable materials through the apparatus, and a receptacle installed onto the outlet port for receiving the recyclable materials.

    摘要翻译: 公开了一种用于管理可回收材料的系统,设备和方法。 在一个实施例中,描述了一种装置,该装置包括用于接收可回收材料的入口端口,连接到入口端口的管道,作为用于排出可再循环材料的管道的一部分的出口端口,安装在管子内部的螺旋叶片 以及沿着管纵向轴线的入口端口,用于使可再循环材料通过入口,管和出口移动;马达,其联接到螺旋叶片上,用于旋转螺旋叶片,从而使可再循环材料移动通过该装置;以及 安装在出口上用于接收可回收材料的插座。

    CELLULITE AND FAT REDUCING DEVICE AND METHOD UTILIZING OPTICAL EMITTERS

    公开(公告)号:US20210162231A1

    公开(公告)日:2021-06-03

    申请号:US17171784

    申请日:2021-02-09

    申请人: Terry Ward

    发明人: Terry Ward

    IPC分类号: A61N5/06

    摘要: A cellulite and fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing green light at approximately 529.6 nm, and at approximately 48,860 Lux, measurable at the array.

    Cellulite and fat reducing device and method utilizing optical emitters

    公开(公告)号:US10946210B2

    公开(公告)日:2021-03-16

    申请号:US14532583

    申请日:2014-11-04

    IPC分类号: A61N5/06

    摘要: A cellulite and fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing green light at approximately 529.6 nm, and at approximately 48,860 Lux, measurable at the array.