公开(公告)号：US5084163A

公开(公告)日：1992-01-28

申请号：US612291

申请日：1990-11-13

申请人： Thomas L. Baumann ,  Ronald L. Edwards

发明人： Thomas L. Baumann ,  Ronald L. Edwards

IPC分类号： B01D24/22 ,  B01J8/00

CPC分类号： B01J8/003 ,  B01D24/22 ,  B01D2201/085 ,  B01J2208/00752 ,  B01J2208/00778

摘要： An improved apparatus and process for the operation of a down-flow granular medium bed filter is disclosed. A splash plate for dissipating the force of influent liquid is rotatably connected to support means, allowing the plate to rotate from a position parallel to the bed surface to a position perpendicular to the bed surface upon the liquid above the bed rising to a selected first level. The splash plate is maintained in the perpendicular position for the remainder of the filtration cycle, the backwash cycle and any chemical cleaning cycle, allowing unobstructed operation of the filter bed. The splash plate returns to the original position at the start of another filtration cycle.

摘要翻译： 公开了用于操作下流式颗粒状中床过滤器的改进的装置和方法。 用于消散流入液体的力的飞溅板可旋转地连接到支撑装置，允许板从与床表面平行的位置旋转到垂直于床表面的位置，床上方的液体升高到选定的第一水平 。 在过滤循环的剩余时间，反冲洗循环和任何化学清洗循环中，防溅板保持在垂直位置，允许过滤床无障碍地操作。 在另一个过滤循环开始时，飞溅板返回到原始位置。

公开(公告)号：US07161034B2

公开(公告)日：2007-01-09

申请号：US10828601

申请日：2004-04-20

申请人： Victor P. Chu ,  Zhu Teng ,  Sandra Lewisch ,  Ronald L. Edwards

发明人： Victor P. Chu ,  Zhu Teng ,  Sandra Lewisch ,  Ronald L. Edwards

IPC分类号： C07C233/05 ,  A61K31/165

CPC分类号： C07C237/04 ,  C07C275/40 ,  G01N33/54313 ,  Y02P20/55 ,  Y10S436/811 ,  Y10S436/815

摘要： Lidocaine analogs, latex particle-analog conjugates, and methods of making and using the same. The analogs have the formula: wherein Z comprises a nucleophilic group and optionally a protecting group; L is a linker; R1, R2, R3, R4, R5 are each independently H, a protecting group, or C1 to C6 alkyls, provided that R1 and R3 may form a six membered ring with the nitrogen and carbon atom to which R1 and R3 are attached; R6 and R7 are each independently H or C1 to C20 alkyls; and including salts thereof. The analogs are immobilized on latex particles and prepared for use in assays for lidocaine.

摘要翻译： 利多卡因类似物，胶乳颗粒 - 类似物共轭物，以及制备和使用它们的方法。 类似物具有下式：其中Z包括亲核基团和任选的保护基团; L是连接体; R 1，R 2，R 3，R 4，R 5，...， 各自独立地为H，保护基，或C 1至C 6烷基，条件是R 1和R 3 >可以与R 1和R 3连接的氮原子和碳原子形成六元环; R 6和R 7各自独立地为H或C 1至C 20烷基; 并包括其盐。 类似物固定在胶乳颗粒上并准备用于利多卡因的测定。

公开(公告)号：US5997691A

公开(公告)日：1999-12-07

申请号：US678529

申请日：1996-07-09

申请人： Navin Gautam ,  Harry V. Lanzillotti ,  Tyrone W. Murray ,  D. Anh Phan ,  Jon R. Butt, Sr. ,  H. Edmund Clark ,  Thomas E. Dougherty ,  Thomas L. Fillio ,  Vladimir Hampl, Jr. ,  Phillip L. Ursery ,  Edwin L. Cutright ,  Ronald L. Edwards

发明人： Navin Gautam ,  Harry V. Lanzillotti ,  Tyrone W. Murray ,  D. Anh Phan ,  Jon R. Butt, Sr. ,  H. Edmund Clark ,  Thomas E. Dougherty ,  Thomas L. Fillio ,  Vladimir Hampl, Jr. ,  Phillip L. Ursery ,  Edwin L. Cutright ,  Ronald L. Edwards

IPC分类号： B05D1/30 ,  A24D1/02 ,  B05B13/04 ,  B05C5/00 ,  B05C5/02 ,  B32B29/02 ,  D21H19/52 ,  D21H19/66 ,  D21H19/68 ,  D21H27/38 ,  D21H11/00

CPC分类号： A24D1/025 ,  B05C5/027 ,  D21H19/66 ,  D21H19/68 ,  B05B13/04 ,  B05C5/025 ,  D21H19/52

摘要： A method and apparatus of manufacturing a web which is striped with add-on material, comprising: a first arrangement which establishes a sheet of base web from a first slurry and moves the established sheet along a first path; a second arrangement for preparing a second slurry; a moving orifice applicator operative so as to repetitively discharge the second slurry upon the moving sheet of base web, the moving orifice applicator comprising: a chamber box arranged to establish a reservoir of the second slurry across the first path; an endless belt having an orifice, the endless belt received through the chamber box; a drive arrangement operative upon the endless belt to continuously move the orifice along an endless path and repetitively through the chamber box, the orifice when communicated with the reservoir being operative to discharge the second slurry from the reservoir through the orifice; a flow distribution system for introducing the second slurry into the chamber box at spaced-apart feed locations along the chamber box; a flow monitoring system for reading fluid pressure at spaced-apart locations along the chamber box; and a controller arranged to identify which of the feed ports is operatively adjacent a monitored location of highest pressure variation, the controller selectively adjusting output of the flow distribution system at the identified feed location counteractively to the highest pressure variation, the controller adjusting output of a remainder of the feed locations counteractively to the output adjustment at the identified feed location.

摘要翻译： 一种用附加材料条纹化的织物的制造方法和装置，包括：第一布置，其从第一浆料建立基片的片材，并沿着第一路径移动所建立的片材; 用于制备第二浆料的第二布置; 移动孔口施加器，其操作以将第二浆料重复地排出到基底幅材的移动片材上，移动孔口施加器包括：腔室箱，布置成在第一路径上建立第二浆料的储存器; 具有孔的环形带，环形带通过室箱接收; 驱动装置，其操作在环形带上，以沿着环形路径连续地移动孔口并重复地穿过室箱，当与储存器连通时，孔口可操作以将第二浆料从储存器排出孔口; 流量分配系统，用于沿着室箱间隔开的进料位置将第二浆料引入室箱; 流量监测系统，用于沿着腔室间隔开的位置读取流体压力; 以及控制器，其布置成识别哪个供给端口可操作地邻近监测的最高压力变化的位置，所述控制器选择性地调节所分配的系统在所识别的进给位置处与最高压力变化相反的输出，所述控制器调整 进给位置的剩余部分与所识别的进给位置处的输出调整成反比。

公开(公告)号：US4475562A

公开(公告)日：1984-10-09

申请号：US312014

申请日：1981-10-16

申请人： Richard E. Thatcher ,  Horace L. Odom ,  Ronald L. Edwards

发明人： Richard E. Thatcher ,  Horace L. Odom ,  Ronald L. Edwards

IPC分类号： A24B5/10 ,  B07B4/02 ,  B07B7/01 ,  B07B9/02 ,  B07B11/06 ,  A24C1/02

CPC分类号： B07B4/02 ,  A24B5/10 ,  B07B11/06 ,  B07B7/01 ,  B07B9/02

摘要： A tobacco leaf mixture containing lighter and heavier fractions is fed into one side of a housing while an airstream flow is introduced at the other side of the housing and in an upwardly directed flow course so as to cause it to entrain the lighter fraction of the mixture therein, with the heavier fraction falling to the bottom of the housing. A suction lift is maintained at the top of the housing to increase the velocity of the lighter fraction containing air flow outwardly from the housing. The lighter fraction containing air flow is then delivered to a separator unit to recover the lighter fraction. The lighter fraction can, for example, be the laminae material from which shredded cigarette tobacco filler is made.

摘要翻译： 将含有较轻和较重馏分的烟草叶混合物进料到壳体的一侧，同时在壳体的另一侧引入气流并且以向上的流动方向引入气流，从而使其夹带混合物的较轻部分 其中较重的部分落到壳体的底部。 在壳体的顶部保持抽吸提升以增加包含空气流的轻馏分从壳体向外的速度。 然后将含有空气流的轻馏分输送到分离器单元以回收较轻馏分。 较轻的部分可以是例如制成卷烟烟草填料的薄片材料。

公开(公告)号：US07279340B2

公开(公告)日：2007-10-09

申请号：US10819831

申请日：2004-04-07

申请人： Victor P. Chu ,  Zhu Teng ,  Steve P. A. Goss ,  Ronald L. Edwards ,  Kelle M. Garvey ,  Timothy J. Gorzynski ,  William D. Bedzyk

发明人： Victor P. Chu ,  Zhu Teng ,  Steve P. A. Goss ,  Ronald L. Edwards ,  Kelle M. Garvey ,  Timothy J. Gorzynski ,  William D. Bedzyk

IPC分类号： G01N33/546 ,  G01N33/543 ,  C07C237/28 ,  G01N37/00

CPC分类号： C07C237/34 ,  C07B2200/11 ,  C07C231/02 ,  Y10S436/815 ,  Y10T436/13

摘要： The present invention relates to immobilized procainamide analogs, as well as to a method of making immobilized procainamide analogs. These immobilized analogs are prepared by activating the carboxyl group on a substituted p-benzoic acid derivative toward nucleophilic attack; reacting the activated benzoic acid derivative with a polyamine to produce the benzoic acid derivative of Formula 3: and binding the benzoic acid derivative of Formula 3 to a latex polymer having functional groups that react with aliphatic amino groups. A method of conducting an immunoassay using the immobilized procainamide analog Formula 3 is described, comprising the steps of preparing a solution comprising said immobilized procainamide analog; adding a sample suspected of containing procainamide to said solution; adding an anti-procainamide antibody to said solution and observing the rate of increase in solution turbidity following antibody addition.

摘要翻译： 本发明涉及固定化的普鲁卡因酰胺类似物，以及制备固定的普鲁卡酰胺类似物的方法。 这些固定化的类似物通过将取代的对苯甲酸衍生物上的羧基活化成亲核攻击来制备; 使活化的苯甲酸衍生物与多胺反应以制备式3的苯甲酸衍生物：将式3的苯甲酸衍生物与具有与脂族氨基反应的官能团的胶乳聚合物结合。 描述了使用固定的普鲁卡酰胺类似物式3进行免疫测定的方法，包括以下步骤：制备包含所述固定的普鲁卡因酰胺类似物的溶液; 在所述溶液中加入怀疑含有普鲁卡因酰胺的样品; 向所述溶液中加入抗普鲁卡因酰胺抗体，并观察抗体加入后溶液浊度的增加速率。

公开(公告)号：US4983308A

公开(公告)日：1991-01-08

申请号：US452454

申请日：1989-12-18

申请人： Ronald L. Edwards

发明人： Ronald L. Edwards

IPC分类号： B01D24/22

CPC分类号： B01D24/22 ,  B01D2201/085

摘要： An improved method for maintaining a granular medium filter in a clean, operable condition is disclosed. The time interval required for the level of liquid above the filter bed to drain from a backwash outlet level to the upper bed surface level following a backwash cycle is monitored. Upon this measured draindown time exceeding a predetermined interval of time, a chemical cleaning cycle is initiated for the granular medium bed filter.

摘要翻译： 公开了一种用于将颗粒状介质过滤器维持在干净，可操作的状态的改进方法。 监测在反冲洗循环之后，过滤床上方的液体水平从反洗出口水平排出到上床表面水平所需的时间间隔。 在该测量的排水时间超过预定的时间间隔时，对颗粒状中床过滤器开始化学清洁循环。