公开(公告)号：US12109517B2

公开(公告)日：2024-10-08

申请号：US17196327

申请日：2021-03-09

申请人： SHIBUYA CORPORATION

发明人： Toshiaki Naka ,  Shigeki Koishi ,  Akira Hatanaka

IPC分类号： B01D29/56 ,  B01D29/62 ,  B01D61/14

CPC分类号： B01D29/56 ,  B01D29/62 ,  B01D61/145 ,  B01D2201/085 ,  B01D2201/088 ,  B01D2311/2649 ,  B01D2311/2692

摘要： A liquid containing exosomes is filtered through a first filter that has a hole diameter that passes the exosomes and blocks cells, and is then stored in a first storage unit (rough filtration step). Next, pressure is applied to the inside of the first storage unit to pump the liquid to a pre-filtration chamber in a second filter that blocks the exosomes so that water in the liquid is filtered out into a post-filtration chamber. The exosome-containing liquid that was not filtered out is returned to the first storage unit, thereby increasing the exosome concentration in the liquid for extraction (concentration step). The exosome-containing concentrate in the first storage unit is then filtered through a third filter having a hole diameter that passes the exosomes and blocks bacteria, and is sent to a recovery unit (sterilization filtration step).

公开(公告)号：US20230391823A1

公开(公告)日：2023-12-07

申请号：US18454131

申请日：2023-08-23

申请人： Hoffmann-La Roche Inc.

发明人： Roberto Falkenstein ,  Christoph Feistl ,  Thorsten Lemm ,  Marc Pompiati ,  Bernhard Spensberger

IPC分类号： C07K1/34 ,  B01D37/02 ,  B01D39/16 ,  B01D39/18 ,  B01D39/20

CPC分类号： C07K1/34 ,  B01D37/025 ,  B01D39/163 ,  B01D2239/0407 ,  B01D39/2079 ,  B01D2201/085 ,  B01D39/18

摘要： Herein is reported a method for the purification or production of a therapeutic polypeptide using the same depth filter multiple times, i.e. a depth filter which has been used before and has been regenerated.
Reported herein is a method for purifying or producing a therapeutic polypeptide, characterized in that the method comprises the following steps:



a) filtering an aqueous composition containing said therapeutic polypeptide and impurities through a depth filter, recovering the flow-through and thereby obtaining said purified therapeutic polypeptide,
b) contacting said depth filter with a regeneration solution and thereby regenerating the depth filter, and
c) repeating steps a) and b) one or more times.

公开(公告)号：US20140124461A1

公开(公告)日：2014-05-08

申请号：US13671068

申请日：2012-11-07

申请人： VEOLIA WATER SOLUTIONS & TECHNOLOGIE

发明人： Herve Buisson ,  Pille Kangsepp ,  Rune Strube ,  Janne Olavi Vaananen

IPC分类号： B01D33/50 ,  B01D33/21 ,  B01D33/72 ,  B01D33/80

CPC分类号： B01D33/50 ,  B01D33/15 ,  B01D33/21 ,  B01D33/804 ,  B01D2201/084 ,  B01D2201/085 ,  B01D2201/088 ,  C02F1/001 ,  C02F1/50 ,  C02F2209/005 ,  C02F2303/16 ,  C02F2303/20

摘要： A rotary disc filter is provided with a system for inhibiting biological fouling from biological growth on filters that form a part of the rotary disc filter. A biocide is pumped from a biocide supply tank to a manifold and mixed with a backwash to form a backwash-biocide solution. The backwash-biocide solution is sprayed onto filter media during a backwashing operation and the presence of the biocide inhibits and eliminates biological growth on the filter media.

摘要翻译： 旋转盘式过滤器设置有用于在形成旋转盘式过滤器的一部分的过滤器上抑制来自生物生长的生物污染的系统。 将杀生物剂从杀菌剂供应罐泵送到歧管并与反冲洗混合以形成反冲洗杀菌剂溶液。 在反冲洗操作期间将反冲洗杀菌剂溶液喷洒到过滤介质上，并且杀生物剂的存在抑制和消除过滤介质上的生物生长。

公开(公告)号：US20120055887A1

公开(公告)日：2012-03-08

申请号：US12875519

申请日：2010-09-03

申请人： Johnny Leon LOVE

发明人： Johnny Leon LOVE

IPC分类号： B01D29/62

CPC分类号： B01D33/50 ,  B01D33/073 ,  B01D33/275 ,  B01D33/39 ,  B01D33/54 ,  B01D33/56 ,  B01D2201/085

摘要： A filter assembly and method of filtering a fluid containing particulates is provided having a filter element mounted on a horizontal mandrel, whereby the filter element and mandrel are rotatable within a housing during a self-cleaning step, wherein the filter element is immersed and agitated in a cleaning liquid followed by high speed rotation while a rinsing liquid is delivered to the core of the filter element. An ultrasonic transducer in the housing may be activated while the filter element is immersed in the cleaning liquid to assist in removing accumulated particulates from the filter element.

摘要翻译： 提供了一种过滤器组件和包含微粒的流体过滤方法，其具有安装在水平心轴上的过滤器元件，由此过滤器元件和心轴在自清洁步骤期间可在壳体内旋转，其中过滤元件浸入并搅拌 清洗液体，然后高速旋转，同时将冲洗液体输送到过滤元件的芯部。 当过滤元件浸入清洁液体中时，壳体中的超声波换能器可以被激活，以帮助从过滤元件去除积聚的微粒。

公开(公告)号：US20100237025A1

公开(公告)日：2010-09-23

申请号：US12406694

申请日：2009-03-18

申请人： John L. Geibel ,  Eugene M. Vegso ,  Christopher J. Ball ,  Robert L. Laird ,  Thomas M. Getting ,  Dean T. Berkebile

发明人： John L. Geibel ,  Eugene M. Vegso ,  Christopher J. Ball ,  Robert L. Laird ,  Thomas M. Getting ,  Dean T. Berkebile

IPC分类号： B01D35/16 ,  B08B3/04 ,  B01D29/66 ,  B08B9/00

CPC分类号： B01D24/24 ,  B01D24/46 ,  B01D2201/085

摘要： The present invention is related to a method and system for cleaning a media support structure in a filter cell in a liquid filter system, wherein a cleaning solution does not significantly enter a filter media zone. The method comprises supplying a cleaning solution to a filter cell to a level sufficient to submerge the media support structure, but not to significantly enter the filter media zone. Additionally, the cleaning solution level is monitored to ensure the cleaning solution does not significantly enter the filter media zone. Alternatively, the cleaning solution may be continuously recirculated and reintroduced to the filter cell during the cleaning operation.

摘要翻译： 本发明涉及用于清洗液体过滤系统中的过滤池中的介质支持结构的方法和系统，其中清洗溶液不会显着进入过滤介质区。 该方法包括将清洁溶液提供给过滤池至足以淹没介质支撑结构但不显着进入过滤介质区的水平。 此外，监控清洁液液位以确保清洁溶液不会显着进入过滤介质区域。 或者，清洁溶液可以在清洁操作期间被连续再循环并重新引入过滤池。

公开(公告)号：US20090166283A1

公开(公告)日：2009-07-02

申请号：US11720644

申请日：2005-11-16

申请人： Torsten Hackner

发明人： Torsten Hackner

IPC分类号： B01D33/21 ,  B01D33/68

CPC分类号： B01D33/68 ,  B01D33/21 ,  B01D2201/085 ,  B01D2201/087

摘要： The invention relates to a filter device (1) for purifying polluted liquids, especially waster water, said device consisting of a plurality of interspaced filter elements (4) which form filter modules (3) and are rotatably arranged, in a circular or polygonal manner, in a container (2) containing the untreated liquid. Said filter modules (3) arranged in a circular or polygonal manner form a cavity (14) which is connected to the container (2) by means of a suction opening (12). A cleaning device for cleaning the filter elements (4) by means of purging air is arranged on and/or in the cavity (14). The invention also relates to a method for cleaning filter elements (4) pertaining to a filter device (1). According to said method, rotating filter elements (4) are cleaned by means of purging air during the operation of the filter device. To this end, the filter elements (4) are rotatably arranged in an interspaced and circular or polygonal manner, forming a cavity (14), in a container (2) containing the untreated liquid.

摘要翻译： 本发明涉及一种用于净化污染液体，特别是废水的过滤装置（1），所述装置由多个间隔过滤元件（4）组成，形成过滤器模块（3），并且以圆形或多边形方式可旋转地布置 在含有未处理液体的容器（2）中。 以圆形或多边形布置的所述过滤器模块（3）形成通过抽吸开口（12）连接到容器（2）的空腔（14）。 用于通过吹扫空气清洁过滤器元件（4）的清洁装置设置在空腔（14）和/或中。 本发明还涉及一种用于清洁属于过滤器装置（1）的过滤元件（4）的方法。 根据所述方法，通过在过滤装置的操作期间吹扫空气来清洁旋转过滤元件（4）。 为此，在包含未处理液体的容器（2）中，过滤元件（4）可旋转地以间隔和圆形或多边形方式布置，形成空腔（14）。

公开(公告)号：US6117459A

公开(公告)日：2000-09-12

申请号：US952142

申请日：1998-01-12

申请人： Erik Van Den Eynde ,  Jacques Hermia ,  Georges Rahier

发明人： Erik Van Den Eynde ,  Jacques Hermia ,  Georges Rahier

IPC分类号： B01D37/02 ,  B01D39/04 ,  B01D39/06 ,  B01D41/02 ,  B01J20/26 ,  B01J20/34 ,  C12H1/04 ,  C12H1/06 ,  C12H1/07 ,  C12C11/00 ,  C12C7/00 ,  C12C7/28

CPC分类号： B01D39/04 ,  B01D37/02 ,  B01D39/06 ,  B01D41/02 ,  B01J20/26 ,  C12H1/04 ,  C12H1/063 ,  B01D2201/085

摘要： The invention relates to new regenerable filtration adjuvants which are usable for the filtration of liquids, particularly beer at the end of the secondary fermentation storage, characterized in that they comprise synthetic or natural incompressible polymer grains or natural incompressible grains grains having a sphericity coefficient varying between approximately 0.6 and 0.9. The invention also relates to a method for regenerating a filtration adjuvant.

摘要翻译： PCT No.PCT / IB96 / 00440 Sec。 371日期：1998年1月12日 102（e）日期1998年1月12日PCT提交1996年5月10日PCT公布。 公开号WO96 / 35497 日期1996年11月14日本发明涉及新的可再生过滤佐剂，其可用于在二次发酵储存结束时过滤液体，特别是啤酒，其特征在于它们包含合成或天然不可压缩的聚合物颗粒或具有 球形度系数在约0.6和0.9之间变化。 本发明还涉及一种再生过滤佐剂的方法。

公开(公告)号：US5374357A

公开(公告)日：1994-12-20

申请号：US33860

申请日：1993-03-19

申请人： Daniel L. Comstock ,  Lee A. Durham ,  Mark A. Warren ,  Bryce P. Anderson

发明人： Daniel L. Comstock ,  Lee A. Durham ,  Mark A. Warren ,  Bryce P. Anderson

IPC分类号： B01D24/10 ,  B01D37/03 ,  C02F1/28 ,  C02F1/54

CPC分类号： B01D37/03 ,  B01D24/105 ,  B01D2201/085

摘要： Colloidal matter is removed from a fluid flow by first adsorbing a coagulant onto the surface of a finely divided filter media, and thereafter passing a colloid-containing fluid through the filter media. The adsorbing of coagulant is accomplished with the filter off-line, and it is returned on-line for filtering of the fluid. After the coagulant is adsorbed onto the filter media, it is not necessary to continue feeding coagulant during on-line operation, as the adsorbed coagulant captures the colloidal matter in the fluid and retains it on the surface of the filter media. The captured colloidal matter is removed during back washing of the filter media.

摘要翻译： 通过首先将凝结剂吸附在细碎的过滤介质的表面上，然后使含胶体的流体通过过滤介质，从流体流中除去胶体。 凝结剂的吸附是用离线过滤器完成的，并在线返回以过滤流体。 在凝结剂被吸附到过滤介质上之后，由于吸附的凝结剂捕获流体中的胶体物质并将其保留在过滤介质的表面上，所以在在线操作期间不需要继续供给凝结剂。 在过滤介质的背洗过程中去除捕获的胶体物质。

公开(公告)号：US5019276A

公开(公告)日：1991-05-28

申请号：US469423

申请日：1990-06-04

申请人： Bengt Kock ,  Klas Holm

发明人： Bengt Kock ,  Klas Holm

IPC分类号： B01D24/22 ,  B01D37/03

CPC分类号： B01D37/03 ,  B01D24/22 ,  B01D2201/085

摘要： The invention concerns a method of and a plant for purifying water in an open, solid filter bed (17) in which, after the addition of chemicals, the water to be purified is passed through a filter bed, said filter bed being regenerated by counter-flow flushing, wherein the water to be purified in the filter bed is caused by force to flow through the bed at a constant rate by means of a partial vacuum created by a pump means (20) arranged downstream the bed (17), the flow being kept constant with the aid of a control valve (23) arranged on the pressure side of the pump (20).

摘要翻译： PCT No.PCT / SE88 / 00514 Sec。 371日期1990年6月4日第 102（e）日期1990年6月4日PCT提交1988年10月6日PCT公布。 出版物WO89 / 03239 日本1989年4月20日。本发明涉及一种在开放固体过滤床（17）中净化水的方法和设备，其中在添加化学品之后，待净化的水通过过滤床， 所述过滤床通过逆流冲洗再生，其中在过滤床中待净化的水由力以恒定速率流动通过床，其由布置在下游的泵装置（20）产生的部分真空 借助于设置在泵（20）的压力侧上的控制阀（23）保持流量恒定的床（17）。

公开(公告)号：US4986913A

公开(公告)日：1991-01-22

申请号：US333796

申请日：1989-04-04

申请人： Helmut Schafft

发明人： Helmut Schafft

IPC分类号： B01D24/04 ,  B01D25/00 ,  B01D29/11 ,  B01D39/02

CPC分类号： B01D25/001 ,  B01D29/111 ,  B01D2101/005 ,  B01D2101/02 ,  B01D2201/085 ,  B01D2201/182 ,  B01D2201/34 ,  B01D2201/40 ,  Y10S264/48

摘要： Filter pads, which are made inherently stable by binders and by removal of the binders can be converted in packings to be maintained under substantially constant surface pressure between rigid filter brackets, are produced first as molded bodies from a suspension of filter aids in liquid by depositing granular, fibrous, or fiber-containing filter aids or mixtures of those filter aids in a casting mold, there being used high rates of flow while avoiding turbulences, and adding binders to the suspension so that the molded body can be stabilized by activation of the binder while drying. It is possible in this process also to manufacture multi-layered filter pads, it having been surprisingly found in those multi-layered filter pads that the layer assembly is kept intact during the filtration even in the filter packing that no longer contains binders. The filter pads or the filter packings produced therefrom according to the invention can, when used, and after reflushing and regeneration operations, finally be utilized, after being replaced, as filter aids in the deposit filtration process.