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1.发明授权Assay method using polyhydroxybutyrate and polyphosphate membranes with channels 失效使用聚羟基丁酸酯和聚磷酸盐膜与通道的测定方法公开(公告)号：US06602398B1
公开(公告)日：2003-08-05
申请号：US08615713
申请日：1996-03-13
申请人： Rosetta N. Reusch
发明人： Rosetta N. Reusch
IPC分类号： G01N27327
CPC分类号： G01N33/6872 , A61K9/1271 , C12Q1/025 , G01N2500/00 , Y10T428/2984
摘要： Lipid bilayers which incorporate poly-3-hydroxybutyrate/polyphosphate ion channels. The ion channels are preferably purified polyhydroxybutyrate polyphosphate complexes extracted from organisms or prepared from the individual constituents which have been size selected. The bilayers are useful for testing the affect of various molecules and ions on the channel which correlates to the in vivo result. The bilayers are useful for transporting the channels into cells or other bilayers.
摘要翻译： 含有聚-3-羟基丁酸/多磷酸离子通道的脂质双层。 离子通道优选是从生物体中提取的纯化的聚羟基丁酸酯多磷酸盐复合物或由已经选择尺寸的各个成分制备。 双层可用于测试与体内结果相关的通道上各种分子和离子的影响。 双层对于将通道输送到细胞或其他双层中是有用的。
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2.发明授权Method of using polyhydroxybutyrate and polyphosphate membranes with channels 失效使用聚羟基丁酸酯和多磷酸盐膜与通道的方法
公开(公告)号：US5650330A
公开(公告)日：1997-07-22
申请号：US614690
申请日：1996-03-13
申请人： Rosetta N. Reusch
发明人： Rosetta N. Reusch
IPC分类号： A01N25/28 , A61K9/127 , B01D61/00 , B01D69/00 , B01D69/02 , B32B9/00 , C12Q1/02 , G01N27/26 , G01N27/333 , G01N33/68
CPC分类号： G01N33/6872 , A61K9/1271 , C12Q1/025 , G01N2500/00 , Y10T428/2984
摘要： Lipid bilayers which incorporate poly-3-hydroxybutyrate/polyphosphate ion channels. The ion channels are preferably purified polyhydroxybutyrate polyphosphate complexes extracted from organisms or prepared from the individual constituents which have been size selected. The bilayers are useful for testing the affect of various molecules and ions on the channel which correlates to the in vivo result. The bilayers are useful for transporting the channels into cells or other bilayers.
摘要翻译： 含有聚-3-羟基丁酸/多磷酸离子通道的脂质双层。 离子通道优选是从生物体中提取的纯化的聚羟基丁酸酯多磷酸盐复合物或由已经选择尺寸的各个成分制备。 双层可用于测试与体内结果相关的通道上各种分子和离子的影响。 双层对于将通道输送到细胞或其他双层中是有用的。
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公开(公告)号：US5891642A
公开(公告)日：1999-04-06
申请号：US940034
申请日：1997-09-29
申请人： Rosetta N. Reusch
发明人： Rosetta N. Reusch
IPC分类号： C07K16/12 , G01N33/53 , G01N33/536 , G01N33/537 , G01N33/541
CPC分类号： C07K16/1203 , C07K2317/54
摘要： An analytical method for detecting the presence poly-beta-hydroxybutyrate (PHB), which can be used as an indicator of atherosclerotic risk is disclosed. In the method, antibodies to PHB are used to detect the PHB.
摘要翻译： 公开了一种可用作动脉粥样硬化风险指标的检测多聚β-羟基丁酸酯（PHB）存在的分析方法。 在该方法中，使用针对PHB的抗体来检测PHB。
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公开(公告)号：US5880269A
公开(公告)日：1999-03-09
申请号：US888362
申请日：1992-05-26
申请人： Rosetta N. Reusch
发明人： Rosetta N. Reusch
CPC分类号： C07K16/1203 , C07K2317/54
摘要： An analytical method for detecting the presence poly-beta-hydroxybutyrate (PHB) which can be used as an indicator of atherosclerotic risk. A novel antibody to PHB for use in the preferred analytical method is described.
摘要翻译： 一种检测多聚β-羟基丁酸酯（PHB）的分析方法，可用作动脉粥样硬化风险的指标。 描述了用于优选分析方法的PHB的新型抗体。
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5.发明授权Branched polyhydroxyalkanoate polymer salt electrolytic compositions and method of preparation 失效支链聚羟基链烷酸酯聚合物盐电解组合物及其制备方法
公开(公告)号：US5266422A
公开(公告)日：1993-11-30
申请号：US993701
申请日：1992-12-21
摘要： Compositions and method for providing a solid conductive electrolyte composition containing a polyhydroxyalkanoate (PHA) and a salt of a conductive metal are described. The PHA is biodegradable and biocompatible and provides a basis for batteries which are more environmentally degradable. Naturally occurring polymers including polyhydroxybutyrate (PHB) and polyhydroxyvalerate (PHV) can be used to prepare the compositions.
摘要翻译： 描述了提供含有聚羟基链烷酸酯（PHA）和导电金属的盐的固体导电电解质组合物的组合物和方法。 PHA是可生物降解和生物相容的，为更环境可降解的电池提供基础。 包括聚羟基丁酸酯（PHB）和聚羟基戊酸酯（PHV）的天然存在的聚合物可用于制备组合物。
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公开(公告)号：US5585249A
公开(公告)日：1996-12-17
申请号：US317204
申请日：1994-10-03
申请人： Rosetta N. Reusch
发明人： Rosetta N. Reusch
IPC分类号： A01N25/28 , A61K9/127 , B01D61/00 , B01D69/00 , B01D69/02 , B32B9/00 , C12Q1/02 , G01N27/26 , G01N27/333 , G01N33/68
CPC分类号： G01N33/6872 , A61K9/1271 , C12Q1/025 , G01N2500/00 , Y10T428/2984
摘要： Lipid bilayers which incorporate poly-3-hydroxybutyrate/polyphosphate ion channels. The ion channels are preferably purified polyhydroxybutyrate polyphosphate complexes extracted from organisms or prepared from the individual constituents which have been size selected. The bilayers are useful for testing the affect of various molecules and ions on the channel which correlates to the in vivo result. The bilayers are useful for transporting the channels into cells or other bilayers.
摘要翻译： 含有聚-3-羟基丁酸/多磷酸离子通道的脂质双层。 离子通道优选是从生物体中提取的纯化的聚羟基丁酸酯多磷酸盐复合物或由已经选择尺寸的各个成分制备。 双层可用于测试与体内结果相关的通道上各种分子和离子的影响。 双层对于将通道输送到细胞或其他双层中是有用的。
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7.再颁专利Branched poly(hydroxyalkanoate) polymer salt electrolytic compositions and method of preparation 失效支链聚（羟基链烷酸酯）聚合物盐电解组合物及其制备方法
公开(公告)号：USRE35257E
公开(公告)日：1996-05-28
申请号：US211000
申请日：1994-03-21
摘要： Compositions and method for providing a solid conductive electrolyte composition containing a .[.polyhydroxyalkanoate.]. .Iadd.poly(hydroxyalkanoate) .Iaddend.(PHA) and a salt of a conductive metal are described. The PHA is a biodegradable and biocompatible and provides a basis for batteries which are more environmentally degradable. Naturally occurring polymers including polyhydroxybutyrate (PHB) and polyhydroxyvalerate (PHV) can be used to prepare the compositions.
摘要翻译： 描述了提供含有[聚羟基链烷酸酯]聚（羟基链烷酸酯）（PHA）和导电金属的盐的固体导电电解质组合物的组合物和方法。 PHA是可生物降解和生物相容的，为更环境可降解的电池提供基础。 包括聚羟基丁酸酯（PHB）和聚羟基戊酸酯（PHV）的天然存在的聚合物可用于制备组合物。
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