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8 条记录 (耗时 0.02 秒)

    Diffusion cell with quick release clamp
    1.
    发明授权
    Diffusion cell with quick release clamp 有权
    具有快速释放夹的扩散槽

    公开(公告)号：US06821419B2

    公开(公告)日：2004-11-23

    申请号：US10056186

    申请日：2002-01-28

    申请人： Royal A. Hanson ,  Bruce E. Renslow ,  Steven W. Shaw ,  Jerome S. Elkins

    发明人： Royal A. Hanson ,  Bruce E. Renslow ,  Steven W. Shaw ,  Jerome S. Elkins

    IPC分类号： B01D6508

    CPC分类号： G01N13/00 ,  G01N2001/4016 ,  G01N2013/003

    摘要： A diffusion cell to facilitate the automatic or manual removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percantaneous absorption through a membrane of a substance from a donor chamber into a receptor chamber of the diffusion cell. There is utilized a capillary port through which the test aliquot is to be removed. A refilling tube connects also with the receptor chamber to add receptor liquid into the receptor chamber as the test aliquot is being removed. A quick release clamping apparatus secures the donor housing which contains the donor chamber tightly to the main housing of the diffusion cell.

    摘要翻译： 扩散池，用于自动或手动地从扩散池的受体室移除液体的试样等分试样，以便确定通过物质膜从供体室到扩散池的受体室的吸收。 使用毛细管端口，通过该毛细管孔将待除去的试样等分试样。 当试剂等分试样被去除时，再填充管还与受体室连接，以将受体液体加入到受体室中。 快速释放夹紧装置将包含供体室的供体壳固定到扩散池的主壳体上。

    Dissolution sampling apparatus
    2.
    发明授权
    Dissolution sampling apparatus 有权
    溶出采样仪

    公开(公告)号：US06422098B1

    公开(公告)日：2002-07-23

    申请号：US09407700

    申请日：1999-09-28

    申请人： Royal A. Hanson ,  Bruce E. Renslow ,  Guillermo E. Meneses ,  Steven W. Shaw ,  Robinson C. Russell

    发明人： Royal A. Hanson ,  Bruce E. Renslow ,  Guillermo E. Meneses ,  Steven W. Shaw ,  Robinson C. Russell

    IPC分类号： G06F1546

    CPC分类号： G01N13/00 ,  G01N2013/006

    摘要： A dissolution sampling apparatus which automatically extracts aliquots which contain a dissolved drug in solution from a plurality of dissolution containing flasks and tests each aliquot for the amount of drug dissolved within the aliquot. The sampling apparatus can resupply the removed aliquot. back to its source or the aliquot can be discarded as waste with new media being resupplied to the source. A syringe is used to remove the aliquots. A mechanically operated valve could be used with each syringe or a plurality of solenoids instead of the mechanically operated valve.

    摘要翻译： 一种溶出取样装置，其自动地从多个溶解容器中提取含有溶解的溶解药物的等分试样，并测试每个等分试样中溶解在等分试样中的药物的量。 采样设备可以重新供应取出的等分试样。 回到其来源或等分试样可以作为废物被丢弃，新的媒体被重新供应给源。 使用注射器去除等分试样。 每个注射器或多个螺线管可以使用机械操作的阀，而不是机械操作的阀。

    Diffusion cell
    5.
    发明授权
    Diffusion cell 失效
    扩散细胞

    公开(公告)号：US5198109A

    公开(公告)日：1993-03-30

    申请号：US856350

    申请日：1992-03-23

    申请人： William A. Hanson ,  Steven W. Shaw

    发明人： William A. Hanson ,  Steven W. Shaw

    IPC分类号： G01N1/20 ,  G01N1/34 ,  G01N13/00

    CPC分类号： G01N13/00 ,  G01N1/2035 ,  G01N2001/4016 ,  G01N2013/003

    摘要： A diffusion cell to facilitate the automated removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percutanous absorption through a membrane of a donor fluid from a donor chamber into the receptor chamber of the diffusion cell. There is utilized a sampling port through which the test aliquot is to be removed, the removal being achieved by means of a sample tube which is to be movable into and out of the receptor chamber. Within the receptor chamber is located a stirring device in the form of a helical coil which is to be rotated to achieve stirring and homogeneous mixing of the liquid within the receptor chamber. A refilling tube connects also with the receptor chamber to add liquid into the receptor chamber as the test aliquot has been removed. A leveling tube within the sampling port is to restore the initial preset receptor liquid volume between sampling intervals.

    摘要翻译： 扩散池，用于促进从扩散池的受体室自动移除液体的试样等分试样，以便确定通过供体流体的膜从供体室进入扩散池的受体室的经皮吸收。 利用采样口，通过该采样口将待测试的等分试样去除，通过可移动进入和离开受体室的样品管来实现去除。 在受体室内设有螺旋线圈形式的搅拌装置，该搅拌装置将被旋转以实现液体在受体室内的搅拌和均匀混合。 当测试等分试样已被去除时，再填充管也与受体室连接以将液体添加到受体室中。 取样口内的调平管将在采样间隔之间恢复初始预设受体液体体积。

    Diffusion cell with filter screen
    7.
    发明授权
    Diffusion cell with filter screen 失效
    带滤网的扩散单元

    公开(公告)号：US5296139A

    公开(公告)日：1994-03-22

    申请号：US76965

    申请日：1993-06-16

    申请人： William A. Hanson ,  Steven W. Shaw

    发明人： William A. Hanson ,  Steven W. Shaw

    IPC分类号： B01D61/28 ,  B01D65/10 ,  G01N1/10 ,  G01N1/34 ,  G01N13/00 ,  G01N33/487 ,  B01D65/08

    CPC分类号： G01N13/00 ,  B01D61/28 ,  B01D65/10 ,  G01N1/10 ,  G01N2001/4016 ,  G01N2013/003 ,  G01N33/487

    摘要： A diffusion cell to facilitate the automated removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percutaneous absorption through a membrane of a donor media from a donor chamber into the receptor chamber of the diffusion cell. There is utilized a sampling port through which the test aliquot is to be removed, the removal being achieved by means of a sample tube. Within the receptor chamber is located a stirring device in the form of a helical coil which is to be rotated to achieve stirring and homogeneous mixing of the liquid within the receptor chamber. Mounted within the coil is a filter screen to prevent particulate matter over a certain size from entering the sample tube and clogging such.

    摘要翻译： 扩散池，用于促进从扩散池的受体室自动去除液体的试样等分试样，以便确定通过供体介质的膜从供体室到扩散池的受体室的经皮吸收。 利用采样口，通过该采样口将待测试的等分试样去除，通过样品管实现去除。 在受体室内设有螺旋线圈形式的搅拌装置，该搅拌装置将被旋转以实现液体在受体室内的搅拌和均匀混合。 安装在线圈内的是过滤网，以防止超过一定尺寸的颗粒物质进入样品管并堵塞。

    Half-order centrifugal pendulum vibration absorber system
    8.
    发明授权
    Half-order centrifugal pendulum vibration absorber system 失效
    半级离心摆式减震器系统

    公开(公告)号：US5495924A

    公开(公告)日：1996-03-05

    申请号：US274326

    申请日：1994-07-13

    申请人： Steven W. Shaw ,  Cheng-Tang Lee

    发明人： Steven W. Shaw ,  Cheng-Tang Lee

    IPC分类号： F16F15/14 ,  F16F7/10

    CPC分类号： F16F15/145 ,  Y10T464/50

    摘要： A dynamic vibration absorber for a rotating machinery element preferably of the bifilar pendulum vibration absorber type wherein the absorber system includes one or more pair(s) of masses having identical paths of movement relative to the axis of the rotating element whose vibrations are being absorbed, the individual absorber masses of a given pair moving out-of-phase with respect to one another relative to the rotating element wherein a disturbance torque with a frequency that is a multiple of the rotation rate of the rotating element is absorbed by a one-half relative frequency motion of the corresponding half-order absorber pair. The half-order absorber pairs are driven primarily by centrifugal forces, move with a frequency one-half that of the disturbance torque and use non-linear Coriolis forces as the source of the counteracting torque.

    摘要翻译： 一种用于旋转机械元件的动态振动吸收器，优选地是双轴摆振动吸收器型，其中吸收器系统包括一对或多个质量块，其具有相对于被振动被吸收的旋转元件的轴线具有相同的运动路径， 给定对的相对于旋转元件相对于彼此移动异相的各个吸收体质量，其中具有作为旋转元件的旋转速度的倍数的频率的扰动转矩被一半 相应的半级吸收器对的相对频率运动。 半级吸收器对主要由离心力驱动，以扰动扭矩的一半的频率移动，并使用非线性科里奥利力作为反作用力矩的来源。