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公开(公告)号:US10551384B2
公开(公告)日:2020-02-04
申请号:US15482340
申请日:2017-04-07
发明人: Steven Zheng
IPC分类号: C12Q1/68 , G01N33/574 , A61K31/5377 , A61K31/495 , A61K31/519 , A61K31/4709 , A61K31/4745 , G01N33/50 , C12Q1/6886 , C12N9/12 , A61K31/53
摘要: Certain embodiments of the invention provide a method of detecting the presence of a biomarker associated with resistance to an mTOR kinase inhibitor in a subject, comprising determining the presence of the biomarker in a physiological sample from the subject, wherein the sample comprises a nucleic acid.
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公开(公告)号:US20180209836A1
公开(公告)日:2018-07-26
申请号:US15927710
申请日:2018-03-21
发明人: Yicheng Lu , Pavel I. Reyes , Steven Zheng , Andrew Zheng , Keyang Yang
IPC分类号: G01G3/16 , G01G3/13 , G01N33/483 , G01H11/08 , G01H13/00 , H01L41/113 , H01L41/29
CPC分类号: G01G3/165 , B82Y15/00 , C12M1/34 , C12Q1/025 , C12Q1/04 , G01G3/13 , G01H11/08 , G01H13/00 , G01N29/022 , G01N29/46 , G01N33/4833 , G01N33/5005 , G01N33/5008 , G01N2291/0256 , H01L41/1132 , H01L41/18 , H01L41/1871 , H01L41/29
摘要: A magnesium zinc oxide (MZO) nanostructure modified quartz crystal microbalance (MZOnano-QCM) takes advantage of the unique sensing ability and biocompatibility of MZO-based nanostructures, and combines them with the dynamic impedance spectrum capability of the bulk acoustic wave (BAW) devices including QCM, to form a real-time, noninvasive and label-free cell monitoring biosensor, specifically detecting the susceptibility and resistance of bacterial and fungal strains and cancer cells to various antibiotic and antifungal drugs and anticancer drugs, respectively.
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公开(公告)号:US10801879B2
公开(公告)日:2020-10-13
申请号:US15927710
申请日:2018-03-21
发明人: Yicheng Lu , Pavel I. Reyes , Steven Zheng , Andrew Zheng , Keyang Yang
IPC分类号: H01L41/113 , H01L41/187 , H01L41/18 , G01N29/02 , G01N29/46 , C12Q1/04 , C12Q1/02 , G01N33/50 , C12M1/34 , G01G3/13 , G01H11/08 , G01H13/00 , G01N33/483 , H01L41/29 , G01G3/16 , B82Y15/00
摘要: A magnesium zinc oxide (MZO) nanostructure modified quartz crystal microbalance (MZOnano-QCM) takes advantage of the unique sensing ability and biocompatibility of MZO-based nanostructures, and combines them with the dynamic impedance spectrum capability of the bulk acoustic wave (BAW) devices including QCM, to form a real-time, noninvasive and label-free cell monitoring biosensor, specifically detecting the susceptibility and resistance of bacterial and fungal strains and cancer cells to various antibiotic and antifungal drugs and anticancer drugs, respectively.
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公开(公告)号:US20170299596A1
公开(公告)日:2017-10-19
申请号:US15482340
申请日:2017-04-07
发明人: Steven Zheng
IPC分类号: G01N33/574 , A61K31/4745 , A61K31/519 , G01N33/50 , A61K31/4709 , A61K31/5377 , C12Q1/68 , A61K31/495
摘要: Certain embodiments of the invention provide a method of detecting the presence of a biomarker associated with resistance to an mTOR kinase inhibitor in a subject, comprising determining the presence of the biomarker in a physiological sample from the subject, wherein the sample comprises a nucleic acid.
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