摘要:
A compound represented by the following Formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom or a carboxyl-protecting group, R2 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or a hydroxyl group, R3 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a nitro group, a cyano group, a hydroxyl group or an amino group; R4 represents a hydrogen atom, an amino-protecting group, an alkyl group or a cycloalkyl group, and R5 represents a hydrogen atom, a halogen atom, an alkyl group, an alkenyl group, a cycloalkyl group, an aryl group, an alkoxy group, an alkylthio group, a hydroxyl group, an imino group or an amino group.
摘要:
The present invention provides a 4-oxoquinolizine antibacterial agent having a 2-pyridone skeleton as a partial structure and also having a strong antibacterial effect on gram-positive bacteria, gram-negative bacteria or anaerobic bacteria. The compound having the following formula (I) or a pharmaceutically acceptable salt thereof: wherein: R1 represents hydrogen atom or a carboxyl-protecting group, R2 represents hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxyl group or hydroxyl group, R3 represents phenyl group or an aromatic substituent selected from the group consisting of 5-membered and 6-membered heterocyclic groups and R3 has a substituent selected from the group consisting of a hydrogen atom, a lower alkyl group, a lower alkoxyl group, a nitro group, a cyano group, an amino group, an acyl group, a carbamoyl group and a ureido group, and R4 represents a hydrogen atom or a halogen atom.
摘要:
A step device for a vehicle including a movable step arranged in a doorway opened and closed by a door is disclosed. The step device includes a drive unit, an open/close mechanism, a projection/retraction mechanism, and a plate cam. The open/close mechanism opens or closes the slide door. The projection/retraction mechanism moves a movable step. The plate cam is rotated by the open/close mechanism and engaged with a bushing arranged on the projection/retraction mechanism to enable or disable power transmission between the open/close mechanism and the projection/retraction mechanism. The plate cam includes a first recess and a second recess. The first recess pushes the bushing during rotation of the plate cam when the slide door is in a range of a predetermined open/close position to enable or disable power transmission between the open/close mechanism and the projection/retraction mechanism. The second recess frees the bushing from the pushing during rotation of the plate cam and disables power transmission between the open/close mechanism and the projection/retraction mechanism when the slide door is outside the range of the predetermined open/close position.
摘要:
A rotary holder for a corrugated tube is structured such that an inner rotary body containing a corrugated tube is received in an inner portion of an outer fixing body, and an outer peripheral sliding surface of the inner rotary body slides along an inner sliding surface of the outer fixing body. The outer fixing body is formed by assembling a base member and a cover each having a recessed arch surface on an inner periphery thereof. The inner sliding surface is formed by connecting a recessed arch surface of the base member to a recessed arch surface of the cover. Further, outer retracting surfaces are respectively provided to both end portions of the recessed arch surface of the base member so as to be extended to a tangential direction thereat.
摘要:
A door for a motor vehicle includes an outer panel and an inner panel in which window portions are formed at their upper side region and which are connected at their peripheral portions, a space which is formed between the lower side region of the outer panel and the lower side region of the inner panel and in which a window glass for opening and closing the window portions is disposed so as to be able to move up and down, a module mounting opening formed on the lower side region of the inner panel and a module structure constituted by mounting a plural functional components to a module base, wherein the module base is fluid-tightly fixed to the module mounting opening at its peripheral portion and the module structure is mounted on the inner panel.
摘要:
A rotary holder for a corrugated tube is formed such that an inner rotary body containing a corrugated tube is received in an inner portion of an outer fixing body, and an outer peripheral sliding surface of the inner rotary body may rotate relative to the outer fixing body. The inner rotary body is formed by assembling two divided rotary members, each having a round arch surface on an outer periphery thereof. The outer peripheral sliding surface is formed by abutting a surface of each divided rotary member against each other. Further, a cut surface retracting inside from a rotation locus of the round arch surface in each divided rotary member is formed in each end portion of the round arch surface.
摘要:
In a power supply structure in a sliding structure, the one end of a wire harness 3 is secured to either one of a sliding structure 1 and a body 5. The other end of the wire harness 3 is hung over the other of them. An elastic member 4 is arranged along the wire harness in the longitudinal direction from the one end of the wire harness so that the wire harness is supported by the elastic member. The elastic member 4 may be a lengthy flat spring. The elastic member may be composed of a first spring segment along the outer face of the wire harness and a second spring segment having a small spring constant which protrudes toward a free end of the elastic member. The elastic member may be bent at an intermediate position in the longitudinal direction and arranged on the curved portion of the wire harness. The elastic member may be composed of a flat spring segment along the inner face of the curved portion and a spiral segment. The elastic member may be provided with a harness supporting member. The elastic member may be secured to a protector using a fixing jig. In such a configuration, the looseness of the wire harness when the sliding structure is opened or closed can be surely absorbed in a simple and small structure.
摘要:
A door speed is detected at every predetermined detecting time, and a door position is calculated at a timing detected the door speed. A target speed according to the door position is obtained by a map. A microcomputer calculates a speed difference &Dgr;VD between the target speed and the actual or present speed, and an acceleration/deceleration value &Dgr;VC such as the speed difference between the door speed at the last detecting time and the present detecting time. A duty increasing value and the decreasing value of a PWM duty command value for adjusting a torque of the motor are set based on the speed difference &Dgr;VD and the acceleration/deceleration value &Dgr;VC, the motor is driven by the PWM duty command value based on the duty increasing value and the decreasing value.
摘要:
A door closing apparatus that is adapted to be disposed on a vehicle door having a door inner panel and an indoor trim includes a door lock mechanism having a latch, a pawl and a latch lever fixedly secured to a rotary shaft of the latch, a bracket adapted to be supported in a fixed relationship with respect to the door panel, and a passive lever rotatably supported by the bracket and provided with a free end portion adapted to contact the latch lever, and a drive source which rotates the passive lever. A shaft portion rotatably supports the passive lever with respect to the bracket, and a nut threadedly engages the shaft portion and is removable from the shaft portion, with the nut being positioned at a side of the bracket facing the indoor trim. In the event the latch lever is unable to rotate (e.g., due to disconnection of an electrical wire or motor malfunction), the indoor trim of the vehicle door can be partially peeled off and the nut removed to manually move the passive lever.
摘要:
In a door closer device which requires at least three switches consisting of a half door detection switch, a full lock (completely closing) detection switch and a switch for detecting the return to the initial position, the number of switches can be reduced. Two cam switch operating portions are formed on a cam plate fixedly secured to an output shaft of a motor. The motor is stopped by making use of one operating portion and the motor is rotated in a reverse direction by making use of the other operating portion.