Electrophoresis device
    1.
    发明申请
    Electrophoresis device 审中-公开
    电泳装置

    公开(公告)号:US20050067285A1

    公开(公告)日:2005-03-31

    申请号:US10913517

    申请日:2004-08-09

    CPC分类号: G01N27/44782 G01N27/44721

    摘要: The present invention is related to the decrease of crosstalk, in which part of light emission from a specific capillary is overlayed on the light emission position of its adjoining capillaries and is detected as signal from adjacent capillaries. Study conducted by the inventor has found that the crosstalk contains at least the following components. The signal light from a capillary may propagate through an adjoining capillary or a plurality of capillaries, the reflection at the inner surface of the outer diameter of quartz capillary makes plural signal paths to the photodetector. The crosstalk component may be focused at a point at a predetermined distance from the center axis of the capillary. The present invention is aimed at the control of the range of image to be detected as the capillary signal among the images focused on the photodetector from the capillaries. The present invention may decrease the crosstalk by controlling the detection of the light emission from the adjacent capillaries.

    摘要翻译: 本发明涉及串扰的减少,其中来自特定毛细管的光发射的一部分覆盖在其相邻的毛细管的发光位置上,并被检测为来自相邻毛细管的信号。 发明人进行的研究发现串扰至少包含以下组件。 来自毛细管的信号光可以通过邻接的毛细管或多个毛细管传播,石英毛细管的外径的内表面的反射使得到达光电检测器的多个信号路径。 串扰分量可以聚焦在距离毛细管的中心轴预定距离的点处。 本发明的目的在于控制从毛细管聚焦在光电检测器上的图像中的毛细管信号的被检测图像的范围。 本发明可以通过控制来自相邻毛细管的光发射的检测来减小串扰。

    Electrophoresis apparatus
    7.
    发明申请
    Electrophoresis apparatus 审中-公开
    电泳仪

    公开(公告)号:US20060076239A1

    公开(公告)日:2006-04-13

    申请号:US11245491

    申请日:2005-10-07

    IPC分类号: G01N27/447

    CPC分类号: G01N27/447

    摘要: In an electrophoresis apparatus comprising capillaries for containing therein fluorescence-labeled substances, and a sensor for irradiating the capillaries with exciting light and detecting fluorescences, the sensor has a substrate including a datum surface for holding thereon the capillaries, and a groove sinking from the datum surface, and the groove has a plurality of reflecting surfaces for reflecting thereon the fluorescences emitted from the capillaries by a plurality of times.

    摘要翻译: 在包括用于在其中含有荧光标记物质的毛细管的电泳装置和用于用激发光照射毛细管并检测荧光的传感器中,传感器具有包括用于保持毛细管的基准表面的基底和从基准面凹下的凹槽 表面,并且凹槽具有多个反射表面,用于在其上反射从毛细管发射的荧光多次。

    Capillary array and capillary electrophoresis apparatus
    10.
    发明授权
    Capillary array and capillary electrophoresis apparatus 有权
    毛细管阵列和毛细管电泳仪

    公开(公告)号:US07473342B2

    公开(公告)日:2009-01-06

    申请号:US11395158

    申请日:2006-04-03

    IPC分类号: G01N27/00

    CPC分类号: G01N27/44708

    摘要: In a case where the temperature of capillaries cannot be controlled rapidly in accordance with the change of the amount of heat generated from the capillaries, the phoretic speed of the sample is not controlled constant to lower the analyzing performance for the sample. This invention intends to stabilize the electrophoretic speed. The surface of a substrate on which a plurality of capillaries are arranged is in contact with a member capable of temperature control thereby controlling the temperature of the capillaries. Since a member capable of controlling the temperature and the capillaries are in direct contact with each other according to the invention, the temperature of the capillary can be controlled rapidly at a high accuracy, so that electrophoretic speed is stabilized.

    摘要翻译: 在毛细管的温度不能根据毛细管产生的热量的变化而不能快速控制的情况下,不将样品的凝胶速度控制在一定程度以降低样品的分析性能。 本发明旨在稳定电泳速度。 其上布置有多个毛细管的基板的表面与能够进行温度控制的构件接触,从而控制毛细管的温度。 由于根据本发明能够控制温度和毛细管的构件彼此直接接触,所以可以高精度地快速地控制毛细管的温度,使得电泳速度稳定。