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125 条记录 (耗时 0.03 秒)

    Method for inhibiting infection of human T-cells
    1.
    发明授权
    Method for inhibiting infection of human T-cells 失效
    抑制人类T细胞感染的方法

    公开(公告)号：US4840941A

    公开(公告)日：1989-06-20

    申请号：US144131

    申请日：1988-01-15

    申请人： Ryuzo Ueno ,  Ryuji Ueno ,  Sachiko Kuno ,  Akihiko Tabata

    发明人： Ryuzo Ueno ,  Ryuji Ueno ,  Sachiko Kuno ,  Akihiko Tabata

    IPC分类号： A61K31/715 ,  C07H11/00

    CPC分类号： C07H11/00 ,  A61K31/715

    摘要： Method of treatment of diseases caused by retroviruses which comprises administering therapeutically effective amount of a natural or synthetic oligo- or polysaccharide having at least one S-oxoacid group attached to the saccharic carbon atom through a linking group of lower molecular weight or a pharmaceutically acceptable salt thereof to a subject in need of such treatment.

    摘要翻译： 治疗由逆转录病毒引起的疾病的方法，该方法包括给予治疗有效量的具有至少一个S-糖酸基团的天然或合成的寡糖或多糖，其通过低分子量的连接基团或药学上可接受的盐连接到糖质碳原子上 对于需要这种治疗的对象。

    Prostaglandin cathartic
    3.
    发明授权
    Prostaglandin cathartic 失效
    前列腺素

    公开(公告)号：US5317032A

    公开(公告)日：1994-05-31

    申请号：US996495

    申请日：1992-12-30

    申请人： Ryuzo Ueno ,  Ryuji Ueno ,  Sachiko Kuno ,  Tomio Oda

    发明人： Ryuzo Ueno ,  Ryuji Ueno ,  Sachiko Kuno ,  Tomio Oda

    IPC分类号： A61K31/557

    CPC分类号： A61K31/557

    摘要： The present invention relates to cathartics comprising 15-keto-16-halogen-PGs as an essential ingredient without substantive side-effects; the catharic effect is thought mainly caused by an enteropooling effect.

    摘要翻译： 本发明涉及包含15-酮-16-卤素-PG作为必需成分而没有实质性副作用的泻药; 念aric效应主要是由于肠道毒作用引起的。

    Crystalline mixture solid containing maltitol and preparation therefor
    5.
    发明授权
    Crystalline mixture solid containing maltitol and preparation therefor 有权
    含有麦芽糖醇的结晶混合物固体及其制备方法

    公开(公告)号：US06863737B2

    公开(公告)日：2005-03-08

    申请号：US10048585

    申请日：2001-07-03

    申请人： Ryuzo Ueno ,  Akihiko Tabata ,  Junya Honda ,  Yojiro Furukawa

    发明人： Ryuzo Ueno ,  Akihiko Tabata ,  Junya Honda ,  Yojiro Furukawa

    IPC分类号： C07H3/04 ,  C07H15/04 ,  C13F1/02 ,  C07H1/00 ,  C07H1/06 ,  C08B30/00 ,  C13K5/00

    CPC分类号： C07H15/04 ,  C07H3/04

    摘要： A crystalline mixture solid containing maltitol having an oil absorptivity of 0.1 to 6.9 wt % and a bulk density of 0.60 to 0.75 g/cc when it is ground and classified to ensure that at least 70 wt % of the obtained particles should have a particle size of 16 to 50 mesh and a process for producing a crystalline mixture solid containing maltitol, comprising introducing air bubbles into a maltitol aqueous solution. According to this process, a crystalline mixture solid containing maltitol having high solubility and almost no moisture absorption is produced at a high work efficiency and a low cost in a short period of time.

    摘要翻译： 一种含有麦芽糖醇的结晶混合物固体，其研磨时的吸油率为0.1〜6.9重量％，体积密度为0.60〜0.75g / cc，并进行分级，以确保至少70重量％的所得颗粒具有粒径 16至50目的筛网和包含麦芽糖醇的结晶混合物固体的方法，包括将气泡引入到麦芽糖醇水溶液中。 根据该方法，以高工作效率和短时间内的低成本生产含有高溶解度且几乎不吸湿的麦芽糖醇的结晶混合物固体。

    Crystalline mixture solid composition and process for preparation thereof
    8.
    发明授权
    Crystalline mixture solid composition and process for preparation thereof 失效
    结晶混合物固体组合物及其制备方法

    公开(公告)号：US06746541B2

    公开(公告)日：2004-06-08

    申请号：US09958666

    申请日：2001-10-12

    申请人： Ryuzo Ueno ,  Akihiko Tabata ,  Junya Honda ,  Yojiro Furukawa ,  Sho Arai

    发明人： Ryuzo Ueno ,  Akihiko Tabata ,  Junya Honda ,  Yojiro Furukawa ,  Sho Arai

    IPC分类号： C13F300

    CPC分类号： C07H1/08 ,  A23L27/34 ,  C40B40/00

    摘要： A crystalline mixture solid composition which has almost no hygroscopicity, is easy to handle and dissolve and hardly worn by abrasion, and comprises &agr;-D-glucopyranosyl-1,1-mannitol and &agr;-D-glucopyranosyl-1,6-sorbitol and may further comprise &agr;-D-glucopyranosyl-1,1-sorbitol in a certain case is obtained in an extremely short period of time by a power-saving and labor-saving process with a small-scale apparatus. A composition which comprises 20 to 75 wt % of &agr;-D-glucopyranosyl-1,1-mannitol, 23 to 70 wt % of &agr;-D-glucopyranosyl-1,6-sorbitol and 2 to 25 wt % of &agr;-D-glucopyranosyl-1,1-sorbitol and is in a crystalline mixture solid state or has a specific surface area of 0.07 to 0.1 m2/g, and a composition which comprises 30 to 75 wt % of &agr;-D-glucopyranosyl-l,1-mannitol, 25 to 70 wt % of &agr;-D-glucopyranosyl-1,6-sorbitol and has a specific surface area of 0.07 to 0.1 m2/g. The above compositions are produced by a process comprising supplying a raw material, which is obtained by optionally removing trehalulose from a mixture containing isomaltulose and trehalulose produced from cane sugar through an isomerization reaction and hydrogenating into a kneader having a thin and long cooling zone together with seed crystals and discharging the obtained composition from an outlet continuously.

    摘要翻译： 具有几乎没有吸湿性的结晶混合物固体组合物易于处理和溶解并且几乎不被磨损磨损，并且包括α-D-吡喃葡萄糖基-1,1-甘露醇和α-D-吡喃葡萄糖基-1,6-山梨糖醇，并且还可以包含α 通过小型装置的省电省力的方法，在极短的时间内可以获得一定的D-吡喃葡萄糖基-1,1-山梨醇.1。一种组合物，其含有20〜75重量％ α-D-吡喃葡萄糖基-1,1-甘露醇，23〜70重量％的α-D-吡喃葡萄糖基-1,6-山梨醇和2〜25重量％的α-D-吡喃葡萄糖基-1,1-山梨醇， 结晶混合物固态或比表面积为0.07〜0.1m 2 / g，组成为30〜75重量％的α-D-吡喃葡萄糖基-1,1-甘露糖醇，25〜70重量％ 的α-D-吡喃葡萄糖基-1,6-山梨糖醇，其比表面积为0.07〜0.1m 2 / g。上述组合物通过包括供给原料的方法制备， 通过任选地通过异构化反应从蔗糖产生的异麦芽酮糖和海藻糖醇的混合物中任选除去海藻糖糖，并将其与晶种一起氢化成具有薄而长的冷却区的捏合机，并连续从出口排出所得组合物。

    Method for manufacturing powdery crystalline maltitol
    10.
    发明授权
    Method for manufacturing powdery crystalline maltitol 失效
    粉状结晶麦芽糖醇的制造方法

    公开(公告)号：US5304388A

    公开(公告)日：1994-04-19

    申请号：US32785

    申请日：1993-03-17

    申请人： Ryuzo Ueno ,  Tomoe Kanno ,  Yuji Kunimi ,  Akihiko Tabata

    发明人： Ryuzo Ueno ,  Tomoe Kanno ,  Yuji Kunimi ,  Akihiko Tabata

    IPC分类号： C07H15/04 ,  A23L1/09 ,  A61K31/70

    CPC分类号： C07H15/04 ,  Y10S426/804

    摘要： Disclosure is a method for converting maltitol into crystalline powder by very simple procedures and in short time. To an aqueous solution of maltitol with 1-15% by weight of moisture content, seed crystals of maltitol are added and a shearing force is applied continuously at a temperature lower than the melting point of the seed crystals, thus obtaining a powdery crystalline maltitol.

    摘要翻译： 公开是通过非常简单的程序和短时间将麦芽糖醇转化成结晶粉末的方法。 向具有1-15重量％水分含量的麦芽糖醇的水溶液中加入麦芽糖醇的晶种，并且在低于晶种的熔点的温度下连续施加剪切力，从而获得粉末状的结晶麦芽糖醇。