Imaging devices for molecule detection

    公开(公告)号:US09683937B2

    公开(公告)日:2017-06-20

    申请号:US14290615

    申请日:2014-05-29

    Inventor: Brian Vaartstra

    CPC classification number: G01N21/6454

    Abstract: An imager may include an array of pixels formed on a substrate. A chemisorption layer such as a planar chemisorption layer may be deposited over the array of pixels. The chemisorption layer may include active sites that bond with anchoring molecules. The anchoring molecules may be bonded to the planar chemisorption layer in only localized regions each covering a respective pixel of the array of pixels. The image sensor may include a photoresist layer that covers the chemisorption layer. Openings in the photoresist layer may define the boundaries of the localized regions. The anchoring molecules may be bonded only with the chemisorption layer without bonding to the photoresist layer. The anchoring molecules may serve to bond with analyte molecules. By forming the anchoring molecules within only localized regions centered over respective pixels, spatial resolution of the imager when imaging the analyte molecules may be improved.

    Image sensors with metallic nanoparticle optical filters
    2.
    发明授权
    Image sensors with metallic nanoparticle optical filters 有权
    具有金属纳米粒子光学滤光片的图像传感器

    公开(公告)号:US09338350B2

    公开(公告)日:2016-05-10

    申请号:US14291628

    申请日:2014-05-30

    Abstract: An imaging system may include one or more optical filters that include metallic nanoparticles in a matrix. The metallic nanoparticle optical filters may form a color filter array for an imager in the imaging system. Different metallic nanoparticle optical filters may be formed for each desired color. Properties of the metallic nanoparticles and matrices may be varied to achieve the desired optical filtering properties and pass the desired wavelength bands to the imager. As examples, the type of metal, the size of the nanoparticles, the shape of the nanoparticles, and the type of matrix in which the nanoparticles are formed may all influence the optical properties of the resulting metallic nanoparticle optical film.

    Abstract translation: 成像系统可以包括一个或多个包括矩阵中的金属纳米颗粒的滤光器。 金属纳米颗粒光学滤光器可以在成像系统中形成用于成像器的滤色器阵列。 可以为每种所需颜色形成不同的金属纳米颗粒光学滤光器。 可以改变金属纳米颗粒和基质的性质以实现所需的光学过滤性质并将期望的波长带传递到成像器。 作为实例,金属的类型,纳米颗粒的尺寸,纳米颗粒的形状以及其中形成纳米颗粒的基体的类型都可能影响所得金属纳米颗粒光学膜的光学性质。

    Imaging systems with plasmonic color filters
    3.
    发明授权
    Imaging systems with plasmonic color filters 有权
    具有等离子体激光彩色滤光片的成像系统

    公开(公告)号:US09258536B2

    公开(公告)日:2016-02-09

    申请号:US13874771

    申请日:2013-05-01

    Inventor: Brian Vaartstra

    CPC classification number: H04N9/045 G02B5/008

    Abstract: An image sensor integrated circuit may contain image sensor pixels. A channel for receiving a fluid with particles such as fluorescent biological samples may be formed on top of the image sensor. Light-control layers may be interposed between the fluid channel and the top of the image sensor. The light-control layers may include a color filter array, a microlens array over the color filter array, and a plasmonic color filter. The plasmonic color filter may be formed from a patterned metal layer on the color filter array or on the microlens array. The patterned metal layer may include openings that are configured to use plasmonic effects to control the colors of light that pass through the plasmonic color filter. The color filter array and the plasmonic color filter, in combination, may block light from a light source in the system while passing fluorescent light from the sample.

    Abstract translation: 图像传感器集成电路可以包含图像传感器像素。 用于接收具有诸如荧光生物样品的颗粒的流体的通道可以形成在图像传感器的顶部上。 光控制层可以介于流体通道和图像传感器的顶部之间。 光控制层可以包括滤色器阵列,滤色器阵列上的微透镜阵列和等离子体激元滤色器。 等离子体激元彩色滤光片可以由滤色器阵列上的图案化金属层或微透镜阵列形成。 图案化金属层可以包括被配置为使用等离子体激发效应来控制通过等离子体激元滤色器的光的颜色的开口。 组合的滤色器阵列和等离子体激元滤色器可以在从样品传出荧光的同时阻挡来自系统中的光源的光。

    IMAGE SENSORS WITH METALLIC NANOPARTICLE OPTICAL FILTERS
    5.
    发明申请
    IMAGE SENSORS WITH METALLIC NANOPARTICLE OPTICAL FILTERS 有权
    具有金属纳米光学滤光片的图像传感器

    公开(公告)号:US20150350540A1

    公开(公告)日:2015-12-03

    申请号:US14291628

    申请日:2014-05-30

    Abstract: An imaging system may include one or more optical filters that include metallic nanoparticles in a matrix. The metallic nanoparticle optical filters may form a color filter array for an imager in the imaging system. Different metallic nanoparticle optical filters may be formed for each desired color. Properties of the metallic nanoparticles and matrices may be varied to achieve the desired optical filtering properties and pass the desired wavelength bands to the imager. As examples, the type of metal, the size of the nanoparticles, the shape of the nanoparticles, and the type of matrix in which the nanoparticles are formed may all influence the optical properties of the resulting metallic nanoparticle optical film.

    Abstract translation: 成像系统可以包括一个或多个包括矩阵中的金属纳米颗粒的滤光器。 金属纳米颗粒光学滤光器可以在成像系统中形成用于成像器的滤色器阵列。 可以为每种所需颜色形成不同的金属纳米颗粒光学滤光器。 可以改变金属纳米颗粒和基质的性质以实现所需的光学过滤性质并将期望的波长带传递到成像器。 作为实例,金属的类型,纳米颗粒的尺寸,纳米颗粒的形状以及其中形成纳米颗粒的基体的类型都可能影响所得金属纳米颗粒光学膜的光学性质。

    Imaging systems with image pixels having adjustable spectral responses
    8.
    发明授权
    Imaging systems with image pixels having adjustable spectral responses 有权
    具有可调光谱响应的图像像素的成像系统

    公开(公告)号:US09338413B2

    公开(公告)日:2016-05-10

    申请号:US14090876

    申请日:2013-11-26

    Abstract: An imaging system may include an image sensor having an array of image pixels. Some image pixels in the array may be provided with spectral response adjustment structures. For example, a plurality of broadband pixels in the array may include spectral response adjustment structures. The spectral response adjustment structures may be configured to narrow the spectral response of the broadband pixels in high light conditions. For example, the spectral response of the broadband pixels may transition from clear to gray, from clear to green, or from yellow to green as the light level increases. The spectral response adjustment structures may, for example, be formed from photochromic materials or electrochromic elements. Processing circuitry in the imaging system may generate a color correction matrix for an image based at least partly on the state of the spectral response adjustment structures.

    Abstract translation: 成像系统可以包括具有图像像素阵列的图像传感器。 阵列中的一些图像像素可以被提供有光谱响应调整结构。 例如,阵列中的多个宽带像素​​可以包括光谱响应调整结构。 光谱响应调整结构可以被配置为在高光条件下使宽带像素的光谱响应变窄。 例如,随着光级增加,宽带像素的光谱响应可以从清晰转变为灰色,从清晰变为绿色,或从黄色转变为绿色。 光谱响应调节结构可以例如由光致变色材料或电致变色元件形成。 成像系统中的处理电路可以至少部分地基于光谱响应调整结构的状态来生成用于图像的颜色校正矩阵。

Patent Agency Ranking